Hochschulschriftenserver der TH Wildau
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Gründungsausbildung an Hochschulen in Deutschland
No full textDie ersten Entrepreneurship-Kurse an Hochschulen wurden bereits in den 30er Jahren in den USA angeboten. Führende Hochschulen in diesem Bereich sind die Harvard Business School, das Babson College und das MIT, die alle in der Region Boston angesiedelt sind. Entrepreneurship ist eine zentrale Säule im Curriculum vieler amerikanischer Universitäten und Business Schools. Seit in Deutschland in den 90er Jahren die ersten Kurse für Entrepreneurship angeboten wurden, sind eine Reihe von Lehrstühlen für Entrepreneurship und verwandte Themengebiete entstanden. In der vorliegenden Studie wird aufgezeigt, dass eine Vielzahl unterschiedlicher Kurskonzepte in Deutschland existiert und in jüngster Zeit der Anteil der Kurse zu theoretischen Ansätzen des Entrepreneurships zu Lasten praxisorientierter Lehrformate angestiegen ist. Dieser Trend ist insofern alarmierend, da insbesondere praxisorientierte Formate Studierende in die Lage versetzen, unternehmerisch zu handeln
Building Sound Foundations for Smart City Government: The Case of Munich, Germany
Get PDFCity governments around the world have increasingly engaged in “smart city” initiatives. Information and communication technologies (ICTs) are at the core of these initiatives. City governments appear to play impor-tant roles in making the urban spaces, in which they are embedded, more attractive, more competitive, more livable, and smarter. The authors interviewed City officials in Munich, Germany, and asked for the definitions of “smart city,” which they then compared to Munich’s smart city-related program. While the practitioners’ definitions differed in part from those in the academic literature, the smart city overhaul program at Munich city government had a direct relationship to the practitioners’ understanding of smartness. The authors por-tray and discuss the City of Munich institutional architecture overhaul and its expected and realized benefits, and compare the results to those of an earlier study on the City of Seattle. Both city governments evidently pursue different approaches, the effectiveness of which can more readily be assessed only at a future point of the smart city evolution
Leishmania donovani populations in Eastern Sudan: temporal structuring and a link between human and canine transmission
No full textVisceral leishmaniasis (VL), caused by the members of the Leishmania donovani complex, has been responsible for devastating VL epidemics in the Sudan. Multilocus microsatellite and sequence typing studies can provide valuable insights into the molecular epidemiology of leishmaniasis, when applied at local scales. Here we present population genetic data for a large panel of strains and clones collected in endemic Sudan between 1993 and 2001
User Experience as a Personalized Evaluation of an Online Information System
No full textWhile online information systems and platforms are being increasingly used, user expectations or the specific demands that come out of the usage context have received scant attention in previous developments. Therefore a finely structured, analytical instrument for evaluating information artefacts with specific emphasis on actors and usage was implemented in the Moodle learning platform for Moodle course room evaluation and tested with different student groups. Some surprising results came out of the discussion between the instructor and students. Moreover, this instrument, TEDS*MOODLE, can be scaled and flexibly customized and thus also integrated into existing e-government services and administrative networks
Screening and genetic characterization of thermo-tolerant Synechocystis sp. PCC6803 strains created by adaptive evolution
No full textTemperature tolerance is an important aspect for commercial scale outdoor cultivation of microalgae and cyanobacteria. While various genes are known to be related to Synechocystis sp. PCC6803's heat shock response, there is very limited published data concerning the specific genes involved in long term thermal tolerance. We have previously used random mutagenesis and adaptive evolution to generate a mixture of strains of Synechocystis sp. PCC6803 with significantly increased thermal tolerance. The genetic modifications leading to the phenotypes of the newly generated strains are the focus of this work
Light-addressable amperometric electrodes for enzyme sensors based on direct quantum dot-electrode contacts
No full textQuantum dots allow the generation of charge carriers upon illumination. When these particles are attached to an electrode a photocurrent can be generated. This allows their use as a light-switchable layer on the surface. The QDs can not only exchange electronics with the electrode, but can also interact with donor or acceptor compounds in solution providing access to the construction of signal chains starting from an analytic molecule. The magnitude and the direction of the photocurrent depend on several factors such as electrode polarization, solution pH and composition. These defined dependencies have been evaluated with respect to the combination of QD-electrodes with enzyme reactions for sensorial purpose. CdSe/ZnS-QD-modified electrodes can be used to follow enzymatic reactions in solution based on the oxygen sensitivity. In order to develop a photoelectrochemical biosensor, e.g. glucose oxidase is immobilized on the CdSe/ZnS-electrode. One immobilization strategy applies the layer-by-layer-technique of GOD and a polyelectrolyte. Photocurrent measurements of such a sensor show a clear concentration dependent behavior. The principle of combing QD oxidase. The sensitivity of quantum dot electrodes can be influenced by additional nanoparticles, but also by multiple layers of the QDs. In another direction of research it can be influenced by additional nanoparticles, but also by multiple layers of the QDs. In another direction of research it can be demonstrated that direct electron transfer from excited quantum dots can be achieved with the redox protein cytochrome c. This allows the detection of the protein, but also interaction partners such as a enzymes or superoxide
The role of helium implantation induced vacancy defect on hardening of tungsten
No full textVacancy-type defects created by helium implantation in tungsten and their impact on the nano-hardness characteristics were investigated by correlating the results from the positron annihilation spectroscopy and the nano-indentation technique. Helium implantation was performed at room temperature (RT) and at an elevated temperate of 600 °C. Also, the effect of post-annealing of the RT implanted sample was studied. The S parameter characterizing the open volume in the material was found to increase after helium irradiation and is significantly enhanced for the samples thermally treated at 600 °C either by irradiation at high temperature or by post-annealing. Two types of helium-vacancy defects were detected after helium irradiation; small defects with high helium-to-vacancy ratio (low S parameter) for RT irradiation and large defects with low helium-to-vacancy ratio (high S parameter) for thermally treated tungsten. The hardness of the heat treated tungsten coincides with the S parameter, and hence is controlled by the large helium-vacancy defects. The hardness of tungsten irradiated at RT without thermal treatment is dominated by manufacturing related defects such as dislocation loops and impurity clusters and additionally by trapped He atoms from irradiation effects, which enhance hardness. He-stabilized dislocation loops mainly cause the very high hardness values in RT irradiated samples without post-annealing
Ein Schmökerabend als neues Format für die Lange Nacht einer wissenschaftlichen Bibliothek
No full textMit dem Schmökerabend soll ein neues Veranstaltungsformat speziell für wissenschaftliche Bibliotheken, wie der Hochschulbibliothek der TH Wildau, geschaffen werden. Diese Art des Zusammenkommens von Jung und Alt und des gemeinschaftlichen Lesens findet in der Regel in öffentlichen Bibliotheken statt. Im Fokus soll die Hochschulbibliothek mit diesem Event als frei zugängliche und öffentliche Bildungseinrichtung stehen. Mit einem gutem Konzept unter einem vorgeschlagenen Motto kann diese Veranstaltung für jede Bibliothek ein Mehrwert sein
High-throughput cultivation and screening platform for unicellular phototrophs
No full textIn this work we describe and test high-throughput methods with the model organism Synechocystis sp. PCC6803. The required technical automation for these processes was achieved with a Tecan Freedom Evo 200 pipetting robot. The cultivation was performed in 2.2 ml deepwell microtiter plates within a cultivation chamber outfitted with programmable shaking conditions, variable illumination, variable temperature, and an adjustable CO2 atmosphere. Each microtiter-well within the chamber functions as a separate cultivation vessel with reproducible conditions. The automated measurement of various parameters such as growth, full absorption spectrum, chlorophyll concentration, MALDI-TOF-MS, as well as a novel vitality measurement protocol, have already been established and can be monitored during cultivation. Measurement of growth parameters can be used as inputs for the system to allow for periodic automatic dilutions and therefore a semi-continuous cultivation of hundreds of cultures in parallel. The system also allows the automatic generation of mid and long term backups of cultures to repeat experiments or to retrieve strains of interest
Towards Decrypting Cryptobiosis—Analyzing Anhydrobiosis in the Tardigrade Milnesium tardigradum Using Transcriptome Sequencing
No full textMany tardigrade species are capable of anhydrobiosis; however, mechanisms underlying their extreme desiccation resistance remain elusive. This study attempts to quantify the anhydrobiotic transcriptome of the limno-terrestrial tardigrade Milnesium tardigradum