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AphaDIGITAL – Digital Speech Therapy Solution for Aphasia Patients with Automatic Feedback Provided by a Virtual Assistant
This paper introduces aphaDIGITAL – a mobile application for speech and language therapy (SLT) support of German-speaking people with aphasia. The app includes automatic speech recognition and text analysis components, which allows giving detailed feedback to the users on different types of errors. Furthermore, the exercises are accompanied by an avatar-based SLT assistant, which is created for this specific purpose. The user performs the exercises, individually configured for her by the SLT practitioner, on a mobile device. Data collection and processing are carried out on the server
Gewerblicher Einsatz von Lastenrädern – Vielfalt der Nutzungsmöglichkeiten
Dieser Beitrag beleuchtet die Vielfalt der Nutzungsmöglichkeiten von Lastenrädern im gewerblichen Einsatz, welche sich am stetig wachsenden Interesse von privatwirtschaftlichen und öffentlichen Organisationen an der Lastenradnutzung zeigt. Am Beispiel der rund 750 Teilnehmenden an einem deutschlandweiten Lastenrad-Testprogramm werden gewerbliche Nutzer charakterisiert. Des Weiteren bietet der Beitrag einen Vorschlag zur Segmentierung der äußerst heterogenen Anwendungsfelder, die sich nicht nur auf Logistik- und Dienstleistungsbranchen beschränken
Aroma component analysis by HS-SPME/GC–MS to characterize Lager, Ale, and sour beer styles
The world of beer is a rich tapestry woven with diverse styles, each with its unique character. Lager, known for its crispness, ferments at lower temperatures, while ale, at warmer ones, boasts a wide spectrum of aromas. Belgian beers dazzle with their complexity, from fruity Trappist ales to sour lambics. German wheat beers, like hefeweizens, charm with their effervescence and fruity undertones. India Pale Ales (IPAs) showcase a hoppy burst, while sour ales tantalize with their tanginess. Craftsmanship, history, and regional ingredients intertwine in this world of brewing, offering aficionados an array of delightful experiences. Research on craft beer aromas is limited, and molecular fingerprint could be crucial. To date, there have been no studies focused on characterizing compound profiles to differentiate beer styles. The Headspace Solid Phase Microextraction (HS-SPME) method provides a rapid and solvent-free approach to volatile compound. The present study aims to characterize the aroma profile of a wide range of beers by using HS-SPME/GC–MS technique combined with multivariate data processing. A total of 120 beer samples were collected and divided into five categories: Pilsen (n = 28); Lager (n = 23); Ale (n = 32); Sour (n = 24); and Belgian Ales (n = 13). Among the Pilsen beers, 18 unique compounds were found for beers with hop extract and hops, and 2 for beers with hop extract (Octyl acetate; and alpha-Terpineol). When comparing the remaining groups to each other, Belgian beers exhibited 5 unique compounds, and Lagers had one (nonanal). Sours and Ales did not have unique compounds but shared 2 distinct compounds with the Belgian group each. We concluded that Belgian beers are the most complex in terms of various aroma-related compounds, and that it is possible to distinguish beers that use pure hops from hop extract
Entwicklung und Evaluierung eines adaptiven Bildverarbeitungssystems für industrielle Qualitätskontrollen unter Berücksichtigung einer hohen Produkt- und Prüfvarianz
Die Bachelorarbeit behandelt die Entwicklung eines eigenen Bildverarbeitungssystems für die MP GmbH Montage- und Prüfsysteme (MP GmbH). Ziel ist es, den Einsatz solcher Systeme in den eigens konstruierten und automatisierten Anlagen zu verbessern und die Abhängigkeit von externen Lösungen zu verringern. Hierfür wurden die Hardware- und Softwarekomponenten eines Bildverarbeitungssystems theoretisch untersucht und hinsichtlich ihrer Eigenschaften sowie Kombinationsmöglichkeiten analysiert. Das System wurde gezielt auf die Anforderungen der MP GmbH ausgelegt, um eine flexible Anpassung an verschiedene Prüfaufgaben und Produktvarianten der Kunden zu ermöglichen. Ein praxisnahes Projekt diente der exemplarischen Implementierung und Validierung des Systems, wobei der Schwerpunkt auf der Auswahl geeigneter Bauteile und der Entwicklung einer maßgeschneiderten Softwarelösung lag. Abschließend wurde das System hinsichtlich Wirtschaftlichkeit und Einsatzfähigkeit geprüft und Herausforderungen sowie Verbesserungspotenziale für zukünftige Projekte aufgezeigt
Overview of FLASHlab@PITZ: the new R&D platform for FLASH radiation therapy and radiation biology
An R&D platform for electron FLASH radiation therapy and radiation biology is being prepared at the Photo Injector Test facility at DESY in Zeuthen (FLASHlab@PITZ). This platform is based on the unique beam parameters available at PITZ: ps scale electron bunches of up to 22 MeV with up to 5 nC bunch charge at MHz bunch repetition rate in bunch trains of up to 1 ms in length repeating at 1 to 10 Hz. It works together with the Technical University of Applied Sciences Wildau (TH Wildau) as partner in close vicinity for the biological resources.
A startup beamline has been installed to allow dosimetry studies and irradiation experiments on chemical, biochemical and biological samples after a 60-degree dispersive arm. The measured dose and dose rates under different beam conditions and first experimental results will be reported in this paper. In addition, a dedicated beamline for FLASHlab@PITZhas been designed for better control of the high brightness electron beams. This includes a dogleg to translate the beam and a 2D kicker system to scan the tiny beam focused by quadrupoles across the samples within less than 1 ms. Simulation studies will be presented to demonstrate the extremely flexible dose parameters with various irradiation options for electron FLASH radiation therapy and radiation biology studies
Effect of the loop forming process on the lifetime of aluminum heavy wire bonds under accelerated mechanical testing
Heavy wire bonding is one of the most common interconnection technologies in manufacturing of high-power electronics. For industrial applications, the long-term reliability of these connections is crucial. Besides the selection of the wire material and the loop geometry itself, the loop forming process parameters also have an influence on the reliability of the wire bond. In this work, the influence of the backward bond head movement during wire bonding process on the quality of wire bond connections was systematically investigated and qualified by cyclic mechanical lifetime tests, surface roughness measurements of the heel area by laser confocal microscopy and static pull tests. The wire bond loops were fabricated with 300 μm aluminum H11 and H14CR wires with different hardness values. The lifetime at low frequency cycle and high frequency cycle regime was determined by means of two different mechanical cyclic test methods operating at 5 Hz and at 60 kHz respectively. The results have shown, that the surface topology of the heel region caused by the initial plastic deformation during the loop forming process has a significant effect on the wire bond failure due to heel cracking. The number of loading cycles to failure shows an inverse correlation with the degree of surface roughness in a so called wrinkling analysis in the low and high frequency cycle regime. The soft wire exhibits different lifetimes compared to the hard ones depending on the testing conditions, while a significant decrease of the lifetime is observed with >30 % reverse movement during bonding in all cases
Patterns of Competitiveness in Russian Gubernatorial Elections
Competitiveness in electoral authoritarian regimes is compromised by management of the electoral arena through various kinds of manipulation. This study links two dimensions of competitiveness, namely fairness and contestation. We analyze the regional heterogeneity of both dimensions for Russian gubernatorial elections held between 2012 and 2019. To assess competitiveness, we use crowd-sourced electoral observation reports and data from the Central Election Commission. Our analysis reveals significant regional variation in both dimensions. Nevertheless, opposition victories are rare and only occur in exceptional cases. Low levels of electoral malpractices seem to be a necessary but not sufficient condition for close election results. Windows of opportunity for the opposition arise only if the regime misperceives the closeness of the race and if the opposition nominates prominent candidates. Overall, these findings shed light on the complex factors influencing the competitiveness of elections in electoral authoritarian regimes like Russia
Evaluation of Bone Radiodensity in Smokers
One of the most prevalent harmful habits that affect people daily is smoking. The aim of our study was to investigate changes in the bone density of the human paranasal sinuses under the influence of smoking using uncertainty calculation.
Material and Methods. The study involved 150 male and female individuals aged 20-40 years, which helps to exclude other factors that could influence the reduction in bone radiodensity (e.g., menopause in women, age-related changes, etc.). The participants were divided into three groups based on the duration of their smoking habits.
Results. Smoking has almost no effect on the maximum bone density. All groups show nearly identical values. In the first group, consisting of individuals who smoked for up to 5 years, the maximum density is 75.22 ± 37.61 Hu. In the second group, those who smoked for up to 10 years have a density of 84.22 ± 42.11 Hu, while in the third control group, the density is 74.29 ± 37.15 Hu. On the other hand, smoking has a greater impact on the minimum radiological bone density of the upper wall of the maxillary sinus. The lowest values are found in the group of individuals who smoked for 10 or more years, with a minimum density of 23.86 ± 11.93 Hu. For those who smoked for up to 5 years, the radiological bone density was 52.65 ± 26.32 Hu. In the control group, the density values were slightly higher than those of individuals who smoked for up to 5 years, with the highest values being 58.12 ± 29.06 Hu.
Conclusion. The study investigated changes in the bone density of the human paranasal sinuses under the influence of smoking, utilizing uncertainty calculation. It was found that the most sensitive indicator to nicotine exposure is the minimum radiological density, which can significantly increase the risk of developing complications. Specifically, the lowest radiological density was observed in the group of individuals who smoked for 10 years or more, with a value of 23.86 ± 11.93 Hu
Uncertainty Estimation Method for Determining Bone Density in Patients with Infiltrating Intraductal Carcinoma Undergoing Anti-Cancer Therapy
Identification of a bone density is crucial in all branches of medicine. Assessing bone density is a labor-intensive process. Bone density is quite unstable and depends on many factors, both physiological (aging, hormonal balance) and pathological (medication use, various underlying conditions).
The aim of our study is to determine bone density in patients with malignant breast tumors undergoing anti-cancer therapy.
Material and Methods. The study included 50 women aged 60-70 years who were diagnosed with infiltrating intraductal carcinoma. According to established protocols, MSCT is recommended for this category of women at intervals of once every six months. The first MSCT scan was performed immediately after the diagnosis was made, before the start of treatment, and the second scan was conducted six months later.
Results. The maximum radiological density was 75.8954±37.9477 Hu in the group of women who had been receiving treatment for six months, compared to 93.9388±46.9694 Hu in the group of patients who did not take the drug. Meanwhile, the minimum density showed a slight increase from 29.7295±14.8647 Hu to 38.6919±19.3460 Hu, which can be attributed to the compensatory mechanisms of the body.
Conclusions. In the course of this study, bone density in patients with infiltrating intraductal carcinoma undergoing anti-cancer therapy was determined using uncertainty estimation. It was found that after six months, the first to respond to changes in density was the maximum bone density
Personalgewinnung und Personalbindung in der Pflege. Einladung zur Qualifizierung von Menschen mit Grundbildungsbedarf
Die aktuelle Situation auf dem Arbeitsmarkt ermöglicht nur marginal die Rekrutierung ausgebildeter Pflegekräfte, um den aktuellen Pflegenotstand zu beheben. Vielerorts ist der Markt quasi „leergefegt“. Daher wird u.a. versucht, nicht oder fachfremd ausgebildete Pflegekräfte mit Grundbildungsbedarf für eine Tätigkeit in der Pflege zu gewinnen, keinesfalls jedoch ohne passgenaue Qualifizierung.
Das durch das Bundesministerium für Bildung und Forschung (BMBF) geförderte Projekt INA-Pflege PLUS zielt auf der Basis eines Wissenschafts-Praxis-Dialogs mittels kooperativer und partizipativer Formate auf die Sensibilisierung und Professionalisierung des Bildungspersonals in der Pflegehilfe/Pflege(fach)assistenzausbildung. Ziel ist, den Diskurs zu den Rahmenbedingungen und den Perspektiven von arbeitsorientierter Grundbildung in der Pflege weiter zu erhellen