Offenburg University of Applied Sciences
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A new approach for state of charge and state of health diagnosis of batteries using voltage-controlled models
Facile Purification and Use of Tobamoviral Nanocarriers for Antibody-Mediated Display of a Two-Enzyme System
Immunosorbent turnip vein clearing virus (TVCV) particles displaying the IgG-binding domains D and E of Staphylococcus aureus protein A (PA) on every coat protein (CP) subunit (TVCVPA) were purified from plants via optimized and new protocols. The latter used polyethylene glycol (PEG) raw precipitates, from which virions were selectively re-solubilized in reverse PEG concentration gradients. This procedure improved the integrity of both TVCVPA and the wild-type subgroup 3 tobamovirus. TVCVPA could be loaded with more than 500 IgGs per virion, which mediated the immunocapture of fluorescent dyes, GFP, and active enzymes. Bi-enzyme ensembles of cooperating glucose oxidase and horseradish peroxidase were tethered together on the TVCVPA carriers via a single antibody type, with one enzyme conjugated chemically to its Fc region, and the other one bound as a target, yielding synthetic multi-enzyme complexes. In microtiter plates, the TVCVPA-displayed sugar-sensing system possessed a considerably increased reusability upon repeated testing, compared to the IgG-bound enzyme pair in the absence of the virus. A high coverage of the viral adapters was also achieved on Ta2O5 sensor chip surfaces coated with a polyelectrolyte interlayer, as a prerequisite for durable TVCVPA-assisted electrochemical biosensing via modularly IgG-assembled sensor enzymes
Rechtskraft bei unberücksichtigter Aufrechnung
Urteilsanmerkung zu BGH v. 14.12.2022 - IV ZB 1/2
Comparative Studies of Anti-Windup Schemes in the Current Control Loop of PMSM Drives at Higher Stator Frequencies
The paper compares different anti-windup strategies for the current control of inverter-fed permanent magnet synchronous machines (PMSM) controlled by pulse-width modulation. In this respect, the focus is on the drive behavior with a relatively large product of stator frequency and sampling time. A requirement for dynamically high-quality anti-windup measures is, among other things, a sufficiently accurate decoupling of the stator current direct axis and quadrature axis components even at high stator frequencies. Discrete-time models of the electrical subsystem of the PMSM are well suited for this purpose, of which the method found to be the most accurate in a preliminary investigation is used as the basis for all anti-windup methods examined. Simulation studies and measurement results document the performance of the compared methods
Towards functionally individualised designed footwear recommendation for overuse injury prevention: a scoping review
Injury prevention is essential in running due to the risk of overuse injury development. Tailoring running shoes to individual needs may be a promising strategy to reduce this risk. Novel manufacturing processes allow the production of individualised running shoes that incorporate features that meet individual biomechanical and experiential needs. However, specific ways to individualise footwear to reduce injury risk are poorly understood. Therefore, this scoping review provides an overview of (1) footwear design features that have the potential for individualisation; and (2) the literature on the differential responses to footwear design features between selected groups of individuals. These purposes focus exclusively on reducing the risk of overuse injuries. We included studies in the English language on adults that analysed: (1) potential interaction effects between footwear design features and subgroups of runners or covariates (e.g., age, sex) for running-related biomechanical risk factors or injury incidences; (2) footwear comfort perception for a systematically modified footwear design feature. Most of the included articles (n = 107) analysed male runners. Female runners may be more susceptible to footwear-induced changes and overuse injury development; future research should target more heterogonous sampling. Several footwear design features (e.g., midsole characteristics, upper, outsole profile) show potential for individualisation. However, the literature addressing individualised footwear solutions and the potential to reduce biomechanical risk factors is limited. Future studies should leverage more extensive data collections considering relevant covariates and subgroups while systematically modifying isolated footwear design features to inform footwear individualisation
RooTri: A Simple and Robust Function to Approximate the Intersection Points of a 3D Scalar Field with an Arbitrarily Oriented Plane in MATLAB
With the function RooTri(), we present a simple and robust calculation method for the approximation of the intersection points of a scalar field given as an unstructured point cloud with a plane oriented arbitrarily in space. The point cloud is approximated to a surface consisting of triangles whose edges are used for computing the intersection points. The function contourc() of Matlab is taken as a reference. Our experiments show that the function contourc() produces outliers that deviate significantly from the defined nominal value, while the quality of the results produced by the function RooTri() increases with finer resolution of the examined grid
Evaluation of precision, accuracy and threshold for the design of vibrotactile feedback in eye tracking applications
Novel approaches for the design of assistive technology controls propose the usage of eye tracking devices such as for smart wheelchairs and robotic arms. The advantages of artificial feedback, especially vibrotactile feedback, as opposed to their use in prostheses, have not been sufficiently explored. Vibrotactile feedback reduces the cognitive load on the visual and auditory channel. It provides tactile sensation, resulting in better use of assistive technologies. In this study the impact of vibration on the precision and accuracy of a head-worn eye tracking device is investigated. The presented system is suitable for further research in the field of artificial feedback. Vibration was perceivable for all participants, yet it does not produce any significant deviations in precision and accuracy
Predictive modeling of lower extremity injury risk in male elite youth soccer players using least absolute shrinkage and selection operator regression
Purpose
To (1) identify neuromuscular and biomechanical injury risk factors in elite youth soccer players and (2) assess the predictive ability of a machine learning approach.
Material and Methods
Fifty-six elite male youth soccer players (age: 17.2 ± 1.1 years; height: 179 ± 8 cm; mass: 70.4 ± 9.2 kg) performed a 3D motion analysis, postural control testing, and strength testing. Non-contact lower extremities injuries were documented throughout 10 months. A least absolute shrinkage and selection operator (LASSO) regression model was used to identify the most important injury predictors. Predictive performance of the LASSO model was determined in a leave-one-out (LOO) prediction competition.
Results
Twenty-three non-contact injuries were registered. The LASSO model identified concentric knee extensor peak torque, hip transversal plane moment in the single-leg drop landing task and center of pressure sway in the single-leg stance test as the three most important predictors for injury in that order. The LASSO model was able to predict injury outcomes with a likelihood of 58% and an area under the ROC curve of 0.63 (sensitivity = 35%; specificity = 79%).
Conclusion
The three most important variables for predicting the injury outcome suggest the importance of neuromuscular and biomechanical performance measures in elite youth soccer. These preliminary results may have practical implications for future directions in injury risk screening and planning, as well as for the development of customized training programs to counteract intrinsic injury risk factors. However, the poor predictive performance of the final model confirms the challenge of predicting sports injuries, and the model must therefore be evaluated in larger samples
Improving Native CNN Robustness with Filter Frequency Regularization
Neural networks tend to overfit the training distribution and perform poorly on out-ofdistribution data. A conceptually simple solution lies in adversarial training, which introduces worst-case perturbations into the training data and thus improves model generalization to some extent. However, it is only one ingredient towards generally more robust models and requires knowledge about the potential attacks or inference time data corruptions during model training. This paper focuses on the native robustness of models that can learn robust behavior directly from conventional training data without out-of-distribution examples. To this end, we study the frequencies in learned convolution filters. Clean-trained models often prioritize high-frequency information, whereas adversarial training enforces models to shift the focus to low-frequency details during training. By mimicking this behavior through frequency regularization in learned convolution weights, we achieve improved native robustness to adversarial attacks, common corruptions, and other out-of-distribution tests. Additionally, this method leads to more favorable shifts in decision-making towards low-frequency information, such as shapes, which inherently aligns more closely with human vision