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On the soil-structure interaction in the seismic response of a monitored masonry school building struck by the 2016-2017 Central Italy earthquake
No full textThe paper discusses the effects of Soil-Foundation-Structure (SFS) interaction on the seismic response of the “Pietro Capuzi” school in Visso, a village located in the Marche region (Italy) that was severely damaged by the 2016-2017 Central Italy seismic sequence. The school is a two-story masonry structure founded on simple enlargements of its loadbearing walls, which are only partially embedded in the alluvial loose soil of the Nera river. The structure was moni-tored as a strategic building by the Italian Seismic Observatory of Structures. The dynamic be-havior of the school under both ambient noise and the recently occurred seismic events was interpreted and compared with numerical simulations. A 3D structural model of the school was realized according to the equivalent frame approach with addition of springs that simulate a compliant base. The spring stiffness, representing the real part of soil-foundation dynamic im-pedance, was calibrated on the soil shear modulus mobilized during the seismic excitation, in-ferred from the deconvolution up to the bedrock of the accelerogram recorded at the under-ground floor of the school. The amplitude of the acceleration and the evolution with time of the frequency resulted from the analyses of the compliant-base and fixed-base models under the three main events of the Central Italy earthquake were compared to the actual records
Denitrification rate and its potential to predict biogenic N2O field emissions in a Mediterranean maize-cropped soil in Southern Italy
No full text24S-hydroxycholesterol affects redox homeostasis in human glial U-87 MG cells.
No full textThe cholesterol metabolite 24(S)-hydroxycholesterol (24S-OHC) allows cholesterol excretion from the brain and was suggested to be critically involved in physiological as well as neurodegenerative processes. It induces on human neuronal cell cultures a dose dependent toxicity associated with increased reactive oxygen species production. Since glial cells play a key role in assisting neuronal function, here we investigated the effects of increased concentrations of 24S-OHC on a glial cell model (human glioblastoma U-87 MG cells). We determined the content of PGC-1α and TFAM, involved in the biogenesis of mitochondria, both mitochondrial complexes activity and protein amount, lipid and protein oxidative damage, cellular reactive oxygen species (ROS) release and both the activities and amount of the antioxidant enzymes glutathione peroxidase and catalase. Low concentration of 24S-OHC increased cellular content of PGC-1α and TFAM and the activities of mitochondrial complexes I and II, with no marked changes in their protein amount. Interestingly, 24S-OHC at lower concentrations reduced while at higher concentration increased lipid and protein oxidative damage. Conversely, the content of nitro-tyrosine increased only with the highest 24S-OHC concentration. Also, cell H2O2 release was reduced by lower and increased by higher 24S-OHC used concentrations. The cell activity of glutathione peroxidase was reduced by 24S-OHC at higher concentration while that of catalase was reduced by all the assayed concentrations. Further, a dose dependent decrease of both enzymes levels was observed. In conclusion, we demonstrated that 24S-OHC exerts different effects on U-87 MG cells depending on its level. At lower concentrations it stimulates cellular processes critical to maintain redox homeostasis, while at higher dose its effect on the glial cell here used resemble its action on neurons
TecnoAgrico: a new approach for crop scale agricultural DSSs.
No full textIn this work is described the approach used, in the frame of a Rural Development Programme project named TecnoAgrico, to develop the modelling core of a crop-scale multi purposes and multi species agricultural DSS. An innovative mixed System Dynamics/data science methodology and a modular architecture are propose
The encyclopedia of volcanoes (second edition), by Haraldur Sigurdsson, Bruce Houghton, Steve McNutt, Hazel Rymer and John Stix (Eds.), 2015. Academic Press, USA. 1,456 pages. Hardback: price $133,00, ISBN 978-0123859389.
No full textRegeneration and resilience: strategies to close the loop for the future of the built environment
No full textConsidering the issue of resilience in the definition of regeneration and maintenance strategies for the built environment requires rethinking the boundaries
and properties that characterize the traditional fields of investigation and intervention related to settlement systems. At the same time there is the need to
identify innovative paradigms to manage the relations between artefacts, contexts, events - predictable and non-predictable - that can modify the expected
functionality in a progressive or disruptive way, with the aim of ensuring the
identity of the settlement systems and enhancing their resilience.
In the paper, the resilience approach is developed according to two complementary perspectives:
- on the one hand, the framing of cultural synergies between the concepts of
fragility, vulnerability, robustness, reliability and adaptability and the issues
of maintenance and regeneration, focusing on the specificities of the information management process;
- on the other hand, the identification of projects and tools for the development and implementation of pilot experiments developed in the territories
New Eye Lens Dose Limit: Status of Knowledge in Campania Hospitals
No full textThe International Commission on Radiation Protection (ICRP) in 2011 recommended the lowering of the annual eye lens dose limit from 150 mSv/year to 20 mSv/year in order to reduce the risk of X-ray-induced lens opacity in medical staff. The purpose of this study was to assess the status of knowledge of the new eye lens dose limit and of the radioprotection culture among operators. To this end, a questionnaire was administered to physicians, X-ray technicians, and nurses working in five hospitals of the Campania region, Italy. A total of 64 questionnaires were collected in the hospital departments in which procedures involving ionizing radiation were routinely performed. The data analyzed yielded the following results: 12 operators affirmed to know the new eye lens dose limit, 53 operators routinely wore lead aprons, and 23 operators used lead glasses. Four workers performed eye lens dosimetry through specific dosimeters. A significant lack of knowledge of the reduced eye lens dose limit suggests the need to implement radioprotection-training programs aimed at raising awareness about the importance of health care in the workplace and at reducing the risk of radio-induced effects to the eye lens
Equivalenza e Idiosincrasia
No full textLa questione della metafora viene dapprima presentata nel confronto Derrida/Ricoeur, poi posta a tema attraverso un’indagine intorno agli estremi dello spettro teorico in cui non si dà più possibilità di metafora: nella pura e semplice equivalenza linguistica e nella più singolare idiosincrasia. Il fenomeno della traduzione consente – di cui si ricapitola il senso filosofico con l’aiuto di un’importante osservazione di Wittgenstein – di portarsi nei pressi del punto idiosincratico che appartiene a ogni lingua in quanto lingua
Visible light-activatable multicargo microemulsions with bimodal photobactericidal action and dual colour fluorescence
No full textIn this contribution we report the design, preparation, and physico-chemical, photophysical and photochemical characterization of photoactivatable microemulsions (MEs) based on Labrasol®, isopropanol and Lauroglycol® FCC as a surfactant, co-surfactant and oily phase, respectively. The MEs co-incorporate, in their oil phase, two lipophilic guests such as a red emitting singlet oxygen (1O2) photosensitizer (PS) and a tailored green emitting nitric oxide (NO) photodonor (NOPD). These two chromofluorogenic units absorb in different spectral windows of the visible range, and their individual photophysical and photochemical properties are well-conserved when co-entrapped in the microemulsions. These features permit the PS and NOPD to operate either individually or in tandem resulting in (i) red, green or both fluorescence emission, (ii) photogeneration of cytotoxic 1O2, NO or both and (iii) amplified photobactericidal action against Staphylococcus aureus due to the combined effect of these two antibacterial agents
A Single-Channel SSVEP-Based Instrument with Off-The-Shelf Components for Trainingless Brain-Computer Interfaces
No full textA high wearable instrument for brain-computer interface (BCI), based on steady-state visual evoked potentials, and conceived with low-cost, off-The-shelf components, is proposed. Peculiar features are: 1) a single-channel differential acquisition; 2) active transducers using dry electrodes with metallic pins; 3) real-Time computation based on Goertzel algorithm, lighter than fast Fourier transform; and 4) absence of training need before the first use. In this way, the proposed instrument overcomes the state-of-The art issues of comfort, wearability, signal quality, and feasibility on limited resources devices (e.g., tablets or smartphones) of BCI applications. The accuracy results of the instrument prototype, assessed in an experimental campaign on human subjects in laboratory, foster its application in wearable biomedical devices