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Overexpressed HspB6 Underlines a Novel Inhibitory Role in KainicAcid-Induced Epileptic Seizure in Rats by Activating the cAMP-PKAPathway
Using Action Research to Implement an Operating Efficiency Initiative in a Local Government
Abstract Maximizing available resources is essential to maintain the economic viability of public institutions. In order to enhance the operational efficiency of the Economic Activities Department of the Madrid City Council (Spain), we have applied an Action Research (AR) initiative. A multidisciplinary collaborative team was created and three AR learning cycles were planned and implemented across the entire management process. Key performance metrics to quantify the improvements were defined, collected and measured. Implementation of the AR initiative, and a multiple case study, led to significant improvements in the processing time of administrative proceedings, as well as the total number of inspections and resolutions. In addition, learning proposals for governments and academy were launched in order to generate and document knowledge which could be applied to other public services. This research work extends the use of AR to public institutions. The application of AR in the selected procedure developed in this city council allowed to generate knowledge in relation to how this methodology must be used to improve other administrative procedures, operational efficiency and, as result, citizen satisfaction.Keywords Actionresearch.Localgovernment.Operationalefficiency.MadridCityCounci
Comparison between Vitek MS, Bruker Biotyper, Vitek2, and API20Efor differentiation of species of the genus Raoultell
AbstractRapid and reliable identification of microorganisms in the clinical laboratory is essential for an early and accurate diagnosisguiding timely therapy. However, conventional methods are sometimes unreliable and show controversial outcomes. Matrixassistedlaser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) has been reported as a rapid and reliablemethod for identification of bacteria and fungi isolated from clinical samples. Members of the genus Raoultella are increasinglyrecognized as clinically relevant. There are difficulties in their identification at the species level since sequencing the 16S rRNAor the rpoB genes does not show conclusive results. The aim of this study has been to compare two MALDI-TOF MS systems(Vitek MS and Bruker Biotyper) with Vitek2 and API20E systems for differentiation of Raoultella species. A collection of 97clinical isolates of Raoultella species was identified with Vitek MS, in parallel with Vitek2 and API, and finally with BrukerBiotyper.Among the twomost widely usedMALDI-TOFMSplatforms, results obtained withVitekMSwere slightly superior tothose obtained with the Bruker Biotyper system, with sensitivities and specificities of 98.9/57.9% and 98.8/37.0%, respectively.The current commercial phenotypic identification systems are not optimized for the identification of Raoultella species. Ourresults indicate that MALDI-TOF-based identification is more accurate and sensitive than that provided by phenotypic methods.Keywords MALDI-TOFMS . Raoultella . VitekMS . Bruker Biotype
Kurt Lewin: Organizational Change
I cover the life, career, and contributions of the German-born and trained psychologistKurt Lewin, whose primary contribution to management thought wasdescribing the process of organizational change. I argue that Lewin, despite thetime in which he lived, was a deeply committed idealist and democrat. I argue thatthese values permeated his work. The merits and weaknesses of his work arediscusse
Perencanaan jembatan beton prategang Way Pengubuan Lampung Tengah (Ruas Gunung Sugih-Terbanggi Subing) [Skripsi]
Bibliografi halaman 156-157xxiii, 155 halaman : ilustrasi ; 28 cm
Perancangan Perpustakaan Umum Dengan Konsep Learning Commons Di Bandar Lampung [CD-Skripsi] / Dhea Anggraini Mangunang
Kewenangan pemerintah Kota Bandar Lampung dalam pembangunan jembatan layang di atas jalan nasional [Skripsi]
Bibliografi halaman 72-73xiv, 71 halaman : ilustrasi ; 28 cm