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    The Activity of Older People Determining Their Functional Abilities During Old Age: A Cross-Sectional Study in Two Major Cities In Indonesia

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    Amidst Indonesia\u27s aging population, this study explores key determinants influencing productivity, the indicators of functional abilities, among older adults in diverse urban/rural settings of East Java and Yogyakarta. The study design used a cross-sectional study surveyed 220 adults (≥60 years; mean age 65.3) via stratified probability sampling. Structured questionnaires assessed holistic health (biological, psychological, social, spiritual, cultural), active ageing determinants (social, habitual, physical, personal, economic, service access), and elderly capability improvement (physical, mental, social, spiritual, cultural health). Binary logistic regression identified predictors of productivity status. The study results showed that holistic health conditions (Exp(B) = 0.983, p = 0.050), active ageing determinants (Exp(B) = 1.16, p =0.000), and improvements in elderly capabilities (Exp(B) = 1.090, p = 0.005) were significant positive predictors of productivity. This Indonesian study demonstrates that specific active ageing determinants and enhanced capabilities are more critical to elderly productivity than general holistic health in a multivariate context. It highlights the need for targeted, regionally adaptable community interventions and age-friendly policies to support productive aging.            

    Effectiveness of Javanese Turmeric (Curcuma Xanthorrhiza Roxb) to Improve Eating Behavior Among Anorexia Children in Bogor

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    Anorexia or lack of desire to eat and loss of appetite is a common issue among children. Some herbs were successfully tested to increase eating behavior, including Javanese turmeric or temulawak. This study aimed to examine the effectiveness of Javanese turmeric on eating behavior scores among children with anorexia. The study was done in Bogor Regency in January 2024. There were 30 children aged 4 to 6 years included in this study who were selected by the non-probability sampling method. Among them, 15 children were categorized into intervention or case group, and the rest as control group. The intervention is giving Javanese turmeric pudding. Before and after giving the intervention, the parents were asked to answer the children\u27s eating behavior questionnaire (CEBQ). The finding by using paired and independent t-tests in this study revealed that Javanese turmeric is significantly effective in improving eating behavior (p-value <0.05) comparing pre and post-tests. This study can encourage the policymakers to do more education and promote of effectiveness of Javanese turmeric for health at the village and school levels. Future studies can improve the food variety made from Javanese turmeric to be more interesting for children

    Effect of The Temperature on The Size of Inhibition Zone of the Clindamycin, Levofloxacin, Tetracycline, and Trimethoprim Activity Against Staphylococcus aureus ATCC 25923

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    Antibiotic sensitivity testing is essential for determining bacterial susceptibility to antibiotics. In disc diffusion testing, several technical factors influence the diameter of the inhibition zone, including incubation temperature, which must be carefully controlled to ensure the validity of test results. This study aims to determine the mean, difference, and analyze the diameter of the inhibition zone of the antibiotics, namely Clindamycin, Levofloxacin, Tetracycline, and Trimethoprim against Staphylococcus aureus on Mueller-Hinton agar media with incubation temperatures of 33°C, 34°C, 35°C, 36°C and 37°C for 18 hours. This research is observational, with a cross-sectional design. The primary data is 100 data on the diameter of the antibiotic inhibition zone, obtained by measuring the diameter of the inhibition zone with different incubation temperatures. The selection of antibiotics is based on the mechanism of action of antibiotics inhibiting bacteria, namely the cell wall or cell membrane that surrounds the bacterial cell; the pieces of machinery that make the nucleic acids DNA and RNA, and the machinery that produces proteins (the ribosome and associated proteins) with a range of inhibition zones based on Internal Quality Control CLSI. The data and the repeated measure statistical test will be processed univariately to determine the significance of the difference in the diameter of the formed inhibition zone using the ANOVA test. The measurement of the inhibition zone diameter on the incubation temperature variation showed a significant difference with a p-value of 0.000 for Levofloxacin, Tetracycline, and Trimethoprim, while the p-value of Clindamycin is 0.010. For the other antibiotics, Levofloxacin, Tetracycline, and Trimethoprim antibiotics, the higher the incubation temperature, the average diameter of the inhibition zone is condensed, while for Clindamycin the higher the incubation temperature, the higher the average diameter of the inhibition zone is the same. Incubation temperature and volume affect the diameter of the antibiotic inhibition zone in the disc diffusion method for the antibiotic sensitivity test. It can be concluded that incubation temperature affects the diameter of the antibiotic inhibition zone in disc diffusion tests. It is recommended for future standardized and precise testing conditions to ensure accurate and reliable antibiotic sensitivity results.             

    Does siPantau Bumil GIS-Based Able to Increase K6 Visits and Reduce Complication for High-Risk Pregnant Women?

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    K6 visits and obstetric complications scope is one indicator of maternal health program services. Scarcely have these indicator’s achievements met the expected targets so innovation is needed to improve them. The method that can be used to increase the accomplishment is digitalization, through the use of applications to provide and improve the health services quality in monitoring pregnant women. The objective is to design and investigate the GIS (Geographical Information System) influence on pregnancy monitoring practice, especially on K6 visits and pregnant women’s high-risk obstetric complications in Pekalongan City. This research uses the Research and Development (R&D) method with a quasi-experimental research design and posttest control group design. The population is pregnant women with high-risk factors at 32 weeks gestation in Pekalongan City. The total sample is 60 people, who were divided into two groups, namely 30 respondents in the intervention group and 30 respondents in the control group. In the intervention group, pregnant women were given monitoring through the Sipantau Bumil application and K6 visit notifications, while in the control group, the K6 visit schedule was written in the KIA book. Moreover, the data analysis used the Chi-Square test. The result is the siPantau Bumil application has increased K6 visits with a significance value of p-value=0.012 (p<0.005). In addition, it also reduces obstetric complications with a significance value of p-value=0.002 (p<0.005). The conclusion is the GIS-based pregnancy monitoring application can increase K6 visits and reduce obstetric complications

    The Role of Hemoglobin in Maintaining Health: A Literature Review

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    The role of hemoglobin in maintaining health is still not fully understood Thoroughly. Therefore, this literature review aims to uncover comprehensively the role of hemoglobin in maintaining health. Objective: The purpose of this literature review is to investigate the role of hemoglobin in maintaining health by collecting and analyzing current findings in the scientific literature. The methodology used is a systematic search through academic databases such as PubMed, Google Scholar, and Scopus using relevant keywords such as "hemoglobin", "health maintenance", and "literature review". Articles that meet the inclusion criteria are selected for analysis. The samples in this review literature are scientific articles published within a certain time frame and focus on the role of hemoglobin in maintaining health. The population studied includes humans of various age groups and health conditions. The results of the analysis stated that hemoglobin plays an important role in maintaining oxygen balance in the body, supporting the function of vital organs, and preventing diseases related to hemoglobin disorders. Factors such as nutrition, environment, and health conditions can affect a person\u27s hemoglobin levels. In conclusion, this literature review confirms that a deep understanding of hemoglobin\u27s role in maintaining health is important for the development of prevention and management strategies for diseases associated with hemoglobin disorders. Thus, further research in this area is needed to improve general well-being

    Barrier from the Side of Stunting Management Policy in Rural Areas of Indonesia: A Qualitative Study

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    This study examines the factors hindering effective stunting management in rural Indonesia, with a particular focus on government policy. Despite ongoing efforts, inadequate attention has been given to key policy-related challenges, including cross-sectoral coordination, merit-based recruitment, budget allocation, and community-based education. This study aims to identify policy barriers that hinder the implementation of stunting mitigation efforts in rural Indonesia. The method used A qualitative approach with a phenomenological design was employed. Data were collected through semi-structured interviews with 32 purposively selected participants, including regional and sub-district heads, village chiefs, health department leaders, and community health center directors, from January to August 2023. The results show that the analysis identified five primary barriers to stunting management: (1) Regulatory inconsistencies, including overlapping inter-agency guidelines that create ambiguity in implementation; (2) Human resource limitations, characterized by a shortage of skilled personnel and nepotistic recruitment practices; (3) Structural and institutional barriers, such as bureaucratic inefficiencies and inter-agency conflicts of interest; (4) Misallocated funding, driven by corruption and weak oversight, leading to ineffective budget distribution; and (5) Community-related factors, including poverty, low nutritional awareness, and unsupportive cultural practices. The conclusion is The conclusion is to addressing these barriers is essential for improving stunting management in rural Indonesia. Enhancing policy consistency, strengthening institutional frameworks, and improving resource allocation are key to overcoming existing challenges. The study recommends periodic regulatory evaluations, enhanced cross-sectoral coordination, and alignment of national policies with local needs. Establishing community-based recruitment and training systems through strategic partnerships could mitigate human resource constraints. Strengthening anti-corruption measures through independent oversight and digital reporting systems. Finally, fostering sustained community education through sociocultural approaches and local leader involvement is critical to increasing awareness and participation in stunting prevention efforts

    The Effect of Edamame Jelly on Lowering Blood Pressure in Primary Hypertension Patients

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    Hypertension is the cause of death in Indonesia, with 23.8% of the 1.7 million population. Management of primary hypertension is non-pharmacological therapy carried out by modifying lifestyle, namely increasing consumption of nuts that contain bioactive components that are beneficial for sufferers of primary hypertension, such as edamame (Glycine max (L.) Merrill). This study aims to determine how giving edamame jelly reduces blood pressure in primary hypertension patients. This research was quasi-experimental and used a pre-post-test control group design. The study population consisted of outpatients at the Sumbersari Jember Community Health Center who met the inclusion and exclusion criteria, totaling 42 subjects. Subjects were randomly divided into treatment and control groups. The intervention group was given amlodipine 5 mg/day and edamame jelly 150 grams/day. The control group was only assigned 5 mg of amlodipine. Statistical tests use the Paired t-test, Wilcoxon signed-rank test, and Mann-Whitney U-tests. The test results showed a significant difference in systolic and diastolic blood pressure between the control and treatment groups with a p-value <0.001. The median systolic blood pressure of the control group was 147.5 mmHg, and that of the treatment group was 130 mmHg. The median diastolic blood pressure in the control group was 90 mmHg, and the treatment group\u27s was 80 mmHg. The reduction in systolic blood pressure in the treatment group was 17.5 mmHg greater than in the control group. The decrease in diastolic blood pressure in the treatment group was 10 mmHg greater than in the control group. Giving 150 grams of edamame jelly/day for 30 days effectively reduces blood pressure in sufferers of primary hypertension.              

    The Ability of The Adaptation Process According to Callista Roy\u27s Theory is Related to Work Stress in Nurses in The Operating Room

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    Nurses in the operating room feel that they lack concentration in carrying out surgery because fatigue during emergency operations can result in increased work stress. The process of adaptation is a way that affects behavior in managing stress. The purpose of the study was to prove that there is a relationship between the ability of the adaptation process according to Callista Roy\u27s theory in nurses with work stress in the operating room of Mardi Waluyo Hospital Blitar. This research method is quantitative using a cross-sectional design. The study sample was 28 nurses in the operating room with the total sampling technique. The independent variable of adaptability of the adaptation process was measured with the questionnaire sheet and the dependent variable of work stress was measured with the DASS 42 questionnaire sheet. Data analysis using Spearman test. The research results show that the ability of the adaptation process was mostly moderate in 17 people (60.7%) and work stress was almost half that of normal stress in 12 people (42.9%). The conclusion is there is a significant relationship between the ability of the adaptation process and nurses\u27 work stress with a p-value of 0.001≤0.05 meaning that there is a significant relationship between the ability of the adaptation process with work stress in nurses in the operating room, the direction of the relationship from r count -0.577* is strongly correlated with the direction of negative relationships, meaning that the increasing adaptability the lower the level of work stress

    Evaluation of Hematotoxicity in Female Wistar Rats Following Sub-Acute Inhalation Exposure to Polyethylene Microplastic

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    Polyethylene (PE) becomes a source of microplastics that can be widely distributed through the digestive and respiratory systems. However, its effects on blood cells are still being investigated. This study aims to analyze the impact of Polyethylene Microplastic (PE-MPs) exposure on the blood of female rats, including erythrocytes, leukocytes, and platelets. This study used female Wistar rats, which were divided into control and PE-MP groups. PE-MP was administered via whole-body inhalation at a concentration of 15 mg/m³ for 4 hours daily for 28 days. The absorption of plastic particles detected in the human bloodstream is likely to occur through mucosal contact (either through ingestion or inhalation). After the exposure period, the rats were euthanized to collect blood samples through the heart. A complete blood count was performed using an automatic hematology analyzer, and blood morphology was analyzed using thin blood smears. This study used the Mann-Whitney test. PE-MP exposure increased erythrocyte and platelet counts without a corresponding rise in leukocytes. Erythrocytes showed abnormal morphology (12.73% with ovalocytes and tear-shaped cells). Erythrocyte indices (MCV, MCH, MCHC) showed no significant differences. Platelet count rose by 1.7% (p-value= 0.017). Leukocyte and neutrophil counts were lower (0.84 and 0.94 times lower, respectively), while lymphocytes and monocytes were higher (1.03 and 1.61 times higher, respectively) in the PE-MP group compared to controls. The neutrophil-to-lymphocyte ratio did not differ significantly. PE-MP exposure in rats disrupts blood parameters, altering erythrocyte morphology and increasing platelet counts. Potential causes include oxidative stress, immune responses, and compensatory mechanisms. Study limitations include a small sample size and exclusive focus on inhalation exposure. Integrating multiple exposure routes (inhalation, ingestion, dermal) could offer a broader view of microplastic impacts. Future research with larger samples, diverse doses and durations, and exploration of additional markers or organ-specific effects is crucial for understanding PE-MP toxicity in real-world scenarios.              

    Risk Factors for Under-Five Children Severe Acute Malnutrition (SAM) in Grobogan Regency

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    Severe Acute Malnutrition (SAM) is a major health risk for children under five. Various factors, such as poor food intake, infections, family size, healthcare participation, maternal nutrition knowledge, and parenting practices, contribute to SAM. However, no studies have specifically examined these factors in under-five children in Grobogan Regency. This study aims to analyze the risk factors associated with severe acute malnutrition among children under five years old in Grobogan Regency. The study employed a quantitative case-control design involving children aged 0-59 months in Grobogan Regency, with 11 children with Severe Acute Malnutrition (SAM) as the case group obtained through total sampling, and 11 well-nourished children as the control group selected via matching. Key variables examined included energy, protein, fat, and carbohydrate intake, as well as infectious diseases, family size, participation in posyandu, maternal nutrition knowledge, and parenting practices. Descriptive analysis outlined the subjects and variables, with bivariate analysis using the Chi-Square test at a 95% confidence level (α=0.05). The results study show that the statistical analysis indicated that inadequate energy intake was significantly associated with SAM (p=0.008, OR=26.667), suggesting that children under five with insufficient energy intake are 26.667 times more likely to experience severe acute malnutrition compared to those with adequate energy intake. In contrast, adequate intake of protein, fat, and carbohydrates, as well as factors such as infectious diseases, family size (p=0.080), participation in posyandu (p=1.000), maternal nutrition knowledge (p=0.476), and parenting practices (p=0.198), did not demonstrate significant associations with SAM among these children. The conclusion is adequate energy intake has been identified as a significant risk factor for SAM among under-five children in Grobogan Regency. Conversely, factors such as adequate intake of protein, fat, and carbohydrates, infectious diseases, family size, participation in posyandu, maternal nutrition knowledge, and parenting practices were not recognized as significant risk factors

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