Jurnal Info Kesehatan
Not a member yet
478 research outputs found
Sort by
Celery (Apium graviolens L.) Herba Extract Capsule Formulation as Anti-Ulcer
No full textThe use of medicinal plants for medicine has been prevalent since ancient times and various plants are used for public health. One of the plants that is often used in herbal medicine is celery, either directly in the form of vegetables or as an extract from the Apium graveolens L plant. Celery extract has previously been given to white mice, and can significantly protect the gastric mucosa and suppress gastric acid secretion. Traditional medicine derived from plant extracts is generally more desirable in tablet or capsule dosage forms. The objective of this study is to determine the best filler in the celery herb extract capsule formulation. This study used a pure experimental method using celery herb extracts which were formulated in capsule dosage forms. The powder fillers used in this formulation are Avicel 101, Avicel 102, and Amylum maydis. The extract capsules were then evaluated for uniformity of weight and disintegration time. Based on the evaluation results, the capsules formulated with Avicel 102 filler gave the best results with an average weight uniformity of 380.98 ± 4.41 mg and disintegration time of 2.64 ± 0.31 minutes. It is advisable to continue the evaluation of the dissolution test for the capsule preparation which gives the best result.The use of medicinal plants for medicine has been prevalent since ancient times and various plants are used for public health. One of the plants that is often used in herbal medicine is celery, either directly in the form of vegetables or as an extract from the Apium graveolens L plant. Celery extract has previously been given to white mice, and can significantly protect the gastric mucosa and suppress gastric acid secretion. Traditional medicine derived from plant extracts is generally more desirable in tablet or capsule dosage forms. The objective of this study is to determine the best filler in the celery herb extract capsule formulation. This study used a pure experimental method using celery herb extracts which were formulated in capsule dosage forms. The powder fillers used in this formulation are Avicel 101, Avicel 102, and Amylum maydis. The extract capsules were then evaluated for uniformity of weight and disintegration time. Based on the evaluation results, the capsules formulated with Avicel 102 filler gave the best results with an average weight uniformity of 380.98 ± 4.41 mg and disintegration time of 2.64 ± 0.31 minutes. It is advisable to continue the evaluation of the dissolution test for the capsule preparation which gives the best result
Relationship between Alcohol Consumption and Impaired Liver Function
No full textEast Nusa Tenggara is a province of high alcohol abuse in Indonesia. Ngada Regency has a prevalence of 38.8%. The high prevalence is inseparable from traditional factors and socio-cultural norms which strongly influence the habit of consuming alcohol, the cold temperature in this area further strengthens this habit. The impact of alcohol consumption is the emergence of various types of diseases, one of which is impaired liver function such as alcoholic liver disease. The objective of this study is to determine the relationship between alcohol consumption and impaired liver function in communities in Bajawa and Golewa Districts, Ngada Regency. This research method is an observational analytic with cross-sectional design. The research subjects were 55 people who consumed alcohol in Golewa and Bajawa Districts, who had met the inclusion criteria. Alcohol consumption was measured by the AUDIT (The Alcohol Use Disorders Identification Test) questionnaire, while the parameter for liver disorders was the level of Gamma Glutamyl Transferase (GGT). The prevalence of liver dysfunction based on GGT examination was 15%. Meanwhile, the relationship between alcohol consumption and impaired liver function was tested with the Spearman correlation with α 0.05, the correlation value was p = 0.413, which means it has a moderate or significant, not too strong relationship. It is recommended that the people of Ngada Regency reduce alcohol consumption so that it can reduce the risk of impaired liver function
The Sunrise Model Approach to the Nutritional Status of Toddlers at the Kupang District Primary Health Center
No full textNutritional problems in toddlers are still a major problem in East Nusa Tenggara Province. The 2018 Basic Health Research results show the percentage of malnourished babies aged 0-23 months in Indonesia was 3.8%, and malnutrition was 11.4%. East Nusa Tenggara is the province with the highest percentage of malnutrition among children aged 0-23 months in 2018. Nutritional problems have broad dimensions, such as socio-economic, cultural, educational, and environmental issues. The research objective is to determine the correlation between the sunrise model\u27s factors and the toddler\u27s nutritional status in the Kupang district. This study is a quantitative observational study with a cross-sectional design. The sampling technique in this study used accidental sampling. The research sample consisted of 169 people at 26 health centers. The results showed that there was a relationship between the use of health technology with the nutritional status of children under five (p=0.023), religious beliefs with family philosophy (p=0.024), family closeness (p=0.005), cultural and lifestyle factors (p=0.007), family economy (p=0.015), parental education (p=0.026), all variables have a significant relationship with the nutritional status of infants/toddlers (p=<0.05). It is concluded that there is a significant relationship between the factors in the sunrise model and the nutritional status of children under five in Kupang district. It is suggested that the sunrise model approach can be used to fix nutritional problems in children under five in Kupang Regency.Nutritional problems in toddlers are still a major problem in East Nusa Tenggara Province. The 2018 Basic Health Research results show the percentage of malnourished babies aged 0-23 months in Indonesia was 3.8%, and malnutrition was 11.4%. East Nusa Tenggara is the province with the highest percentage of malnutrition among children aged 0-23 months in 2018. Nutritional problems have broad dimensions, such as socio-economic, cultural, educational, and environmental issues. The research objective is to determine the correlation between the sunrise model\u27s factors and the toddler\u27s nutritional status in the Kupang district. This study is a quantitative observational study with a cross-sectional design. The sampling technique in this study used accidental sampling. The research sample consisted of 169 people at 26 health centers. The results showed that there was a relationship between the use of health technology with the nutritional status of children under five (p=0.023), religious beliefs with family philosophy (p=0.024), family closeness (p=0.005), cultural and lifestyle factors (p=0.007), family economy (p=0.015), parental education (p=0.026), all variables have a significant relationship with the nutritional status of infants/toddlers (p=<0.05). It is concluded that there is a significant relationship between the factors in the sunrise model and the nutritional status of children under five in Kupang district. It is suggested that the sunrise model approach can be used to fix nutritional problems in children under five in Kupang Regency
The Effect of Prognostıc Factors and Potentıal Treatment Regımens on Fatality Covid-19 Patıents
No full textThe ongoing outbreak of the coronavirus disease 2019 (COVID-19), as named by the World Health Organization, has millions of confirmed cases worldwide and has claimed hundreds of thousands of lives. The virus was named SARS-CoV-2 in February by the International Committee on Taxonomy of Viruses. COVID-19 presents as fever, dry cough, dyspnea, headache, and pneumonia. In a small subset of severe cases, the disease quickly progresses to respiratory failure and even death. This study aimed to know the effects of clinical and laboratory features on investigated death. The diagnosis was based on typical findings in thoracic computed tomography (CT) and positive results of the Real-Time Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) SARS-CoV-2. The demographic characteristics of COVID-19 patients treated, accompanying comorbid conditions and laboratory criteria (blood lymphocyte counts, C Reactive Protein (CRP), D-dimer, Interleukin 6 (IL-6), blood neutrophil count/lymphocyte counts) were collected retrospectively. The results show that 121 cases, 66 (54.54%) were male, 55 (45.46%) were female, and the mean age was ± Std (Min-Max), 59.63 ± 17.4 (22-91). Neutrophil percentage (p = 0.027), neutrophil / lymphocyte ratio (NE / LE) (p = 0.028), CRP (p = <0.001), PCT (p = 0.004), D dimer (p = 0.021) and IL 6 (p = 0.047) in patients with a fatal course, higher values were found than those recovered. Blood lymphocyte count (p = 0.001) and percent (p <0.001) were lower. Number of blood white spheres (p = 0.010), blood neutrophil counts (p = 0.001) and percentage (p <0.001), NE / LE (p0.001), CRP (p <0.001), PCT (p = 0.003) and IL -6 (p <0.001) levels were higher in patients with severe clinical findings than in mild cases. The case death rate was observed as 9%. Covid-19 patients should consider blood neutrophil percentage, blood lymphocyte count, blood lymphocyte percentage, NE / LE, CRP, D dimer, and IL 6 values as an early warning in terms of prognosis. More experience was needed to assess the benefits of immune plasma, tocilizumab, IVIG treatments, and remdesivir therapy recently introduced to the treatment protocol.The ongoing outbreak of the coronavirus disease 2019 (COVID-19), as named by the World Health Organization, has millions of confirmed cases worldwide and has claimed hundreds of thousands of lives. The virus was named SARS-CoV-2 in February by the International Committee on Taxonomy of Viruses. COVID-19 presents as fever, dry cough, dyspnea, headache, and pneumonia. In a small subset of severe cases, the disease quickly progresses to respiratory failure and even death. This study aimed to know the effects of clinical and laboratory features on investigated death. The diagnosis was based on typical findings in thoracic computed tomography (CT) and positive results of the Real-Time Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) SARS-CoV-2. The demographic characteristics of COVID-19 patients treated, accompanying comorbid conditions and laboratory criteria (blood lymphocyte counts, C Reactive Protein (CRP), D-dimer, Interleukin 6 (IL-6), blood neutrophil count/lymphocyte counts) were collected retrospectively. The results show that 121 cases, 66 (54.54%) were male, 55 (45.46%) were female, and the mean age was ± Std (Min-Max), 59.63 ± 17.4 (22-91). Neutrophil percentage (p = 0.027), neutrophil / lymphocyte ratio (NE / LE) (p = 0.028), CRP (p = <0.001), PCT (p = 0.004), D dimer (p = 0.021) and IL 6 (p = 0.047) in patients with a fatal course, higher values were found than those recovered. Blood lymphocyte count (p = 0.001) and percent (p <0.001) were lower. Number of blood white spheres (p = 0.010), blood neutrophil counts (p = 0.001) and percentage (p <0.001), NE / LE (p0.001), CRP (p <0.001), PCT (p = 0.003) and IL -6 (p <0.001) levels were higher in patients with severe clinical findings than in mild cases. The case death rate was observed as 9%. Covid-19 patients should consider blood neutrophil percentage, blood lymphocyte count, blood lymphocyte percentage, NE / LE, CRP, D dimer, and IL 6 values as an early warning in terms of prognosis. More experience was needed to assess the benefits of immune plasma, tocilizumab, IVIG treatments, and remdesivir therapy recently introduced to the treatment protocol
Giving Exclusive Breastfeeding and Maternal Gestational Age Affects the Developmental Delay of Children Aged 3-36 Months
No full textDevelopmental disorders can affect one or more areas of development such as gross motor, fine motor, speaking/using language, and social personality/independence. Factors that influence the development in children can come from internal factors (exclusive breastfeeding, and maternal gestational age) and external factors (maternal age and number of children under five in the family). Early detection of development is very important using the Developmental Pre-Screening Questionnaire or DENVER II. The objective of the study is to identify risk factors that influence delays in the development of children aged 3-36 months. This research is an analytic observational with case control approach. The research location was at Integrated Healthcare Unit, Primary Health Center of Rowosari, Semarang. The total sample of this study was 62 in children aged 3-36 months whose development was analyzed using the Developmental Pre-Screening Questionnaire instrument. The sampling technique used purposive sampling. The variables of this study were exclusive breastfeeding, gestational age, maternal age and the number of children under five in the family. Statistical tests used Chi-Square to analyze the relationship between internal and external factors with the delay in child development. The results show that exclusive breastfeeding (p=0.042) and gestational age (p=0.042) have a significant relationship with the development of children aged 3-36 months, while maternal age factors during pregnancy (p=0.425) and number of children under five (p=0,353) have no significant relationship. Thus, internal factors such as exclusive breastfeeding and maternal gestational age affect the developmental delay of children aged 3-36 months
Antenatal Education with Booklet Media on Knowledge and Readiness of Pregnant Women under the Age of 20 Years
No full textWest Nusa Tenggara Province is one of the areas with high early marriage cases in Indonesia. Pregnancy of women aged 10-19 years who had been pregnant reached 58.8% and currently pregnant 25.2%. The objective of this study is to determine the effect of antenatal education with the booklet media on the knowledge and readiness of pregnant women under the age of 20 in dealing with pregnancy. This research is a quasi-experiment with one group pretest-posttest. This research was conducted in May-June 2019. The population in this study was pregnant women under the age of 20 years. The sampling technique in this study was total sampling with a sample of 30 pregnant women. The analysis used the Wilcoxon Sign Rank Test and Paired Sample T-Test. The results showed that respondents in this study were 16-19 years old with the majority of secondary education and all working as housewives. There was an increase in the value of the level of knowledge and readiness from before and after the intervention was given. Statistical test results on the level of knowledge and readiness obtained p-value = 0.000 before and after given the intervention, showing the influence of antenatal education on the knowledge and readiness of pregnant women under 20 years of age in dealing with pregnancy. Future studies are expected to add to larger sample size and add other relevant variables related to pregnancies under the age of 20 years.West Nusa Tenggara Province is one of the areas with high early marriage cases in Indonesia. Pregnancy of women aged 10-19 years who had been pregnant reached 58.8% and currently pregnant 25.2%. The objective of this study is to determine the effect of antenatal education with the booklet media on the knowledge and readiness of pregnant women under the age of 20 in dealing with pregnancy. This research is a quasi-experiment with one group pretest-posttest. This research was conducted in May-June 2019. The population in this study was pregnant women under the age of 20 years. The sampling technique in this study was total sampling with a sample of 30 pregnant women. The analysis used the Wilcoxon Sign Rank Test and Paired Sample T-Test. The results showed that respondents in this study were 16-19 years old with the majority of secondary education and all working as housewives. There was an increase in the value of the level of knowledge and readiness from before and after the intervention was given. Statistical test results on the level of knowledge and readiness obtained p-value = 0.000 before and after given the intervention, showing the influence of antenatal education on the knowledge and readiness of pregnant women under 20 years of age in dealing with pregnancy. Future studies are expected to add to larger sample size and add other relevant variables related to pregnancies under the age of 20 years
Effectiveness of Breadfruit Leaf Extract (Artocarpus Altilis) as a Mouthwash to Reduce Saliva Viscosity
No full textSaliva is a complex liquid in the mouth that has an important role as self-cleansing. If the viscosity of saliva is getting lower, the possibility of caries will decrease. The use of mouth rinses is one way to maintain oral hygiene. One of the herbs that can be used as medicine is breadfruit leaf (Artocarpus Altilis). The objective of this study is to determine the effect of breadfruit leaf extract (Artocarpus Altilis) as a mouthwash on saliva viscosity in boarding students of the Dental Nursing Department. This type of research is a pre-experiment with the design of One Group Pretest Posttest which was conducted in October-November 2019. The population of this research study was the boarding students of the Dental Nursing Department of the Yogyakarta Health Polytechnic Ministry of Health with a sample size of 40 respondents taken by purposive sampling technique. Data analysis used Paired Sample T-Test and Simple Linear Regression. 62.5% of respondents aged 18 years with female sex were more than men that were 97.5%. The parametric test results using the Paired Sample T-Test showed a significant difference with a value of p=0.000. Simple Linear Regression analysis test results showed that there was a significant influence between the accumulation of salivary viscosity before and after gargling the breadfruit leaf extract (Artocarpus Altilis) concentration of 20%, with a decrease in the means before gargling the breadfruit leaf extract 3.5810 to 2.6025 with a significance value 0.004 (P<0.05). The conclusion of this study is that there is an influence of breadfruit leaf extract (Artocarpus Altilis) as a mouthwash on saliva viscosity in boarding students of the Dental Nursing Department. It is recommended for further research on the use of breadfruit leaf extract (Artocarpus Altilis) as a mouthwash with different concentrations and solvents so as to increase knowledge of the effectiveness of breadfruit leaves as a mouthwash ingredient.Saliva is a complex liquid in the mouth that has an important role as self-cleansing. If the viscosity of saliva is getting lower, the possibility of caries will decrease. The use of mouth rinses is one way to maintain oral hygiene. One of the herbs that can be used as medicine is breadfruit leaf (Artocarpus Altilis). The objective of this study is to determine the effect of breadfruit leaf extract (Artocarpus Altilis) as a mouthwash on saliva viscosity in boarding students of the Dental Nursing Department. This type of research is a pre-experiment with the design of One Group Pretest Posttest which was conducted in October-November 2019. The population of this research study was the boarding students of the Dental Nursing Department of the Yogyakarta Health Polytechnic Ministry of Health with a sample size of 40 respondents taken by purposive sampling technique. Data analysis used Paired Sample T-Test and Simple Linear Regression. 62.5% of respondents aged 18 years with female sex were more than men that were 97.5%. The parametric test results using the Paired Sample T-Test showed a significant difference with a value of p=0.000. Simple Linear Regression analysis test results showed that there was a significant influence between the accumulation of salivary viscosity before and after gargling the breadfruit leaf extract (Artocarpus Altilis) concentration of 20%, with a decrease in the means before gargling the breadfruit leaf extract 3.5810 to 2.6025 with a significance value 0.004 (P<0.05). The conclusion of this study is that there is an influence of breadfruit leaf extract (Artocarpus Altilis) as a mouthwash on saliva viscosity in boarding students of the Dental Nursing Department. It is recommended for further research on the use of breadfruit leaf extract (Artocarpus Altilis) as a mouthwash with different concentrations and solvents so as to increase knowledge of the effectiveness of breadfruit leaves as a mouthwash ingredient
Investigation of Women Employees in Family Health Centers of Eskişehir Province about Normal Birth and Caesarean Birth
No full textUnnecessary caesarean delivery continues to be an increasingly important problem in the world. Thanks to the information and training provided with the right resources, it is possible to reduce the caesarean rates and increase the normal birth rates with the right choices. This study aimed to learn the opinions of female employees in Eskişehir family health centers about normal and caesarean births, to determine important points and develop suggestions for these methods. The population of the study was 170 working women. Factor analysis, 16 items normal birth, and caesarean delivery scale were gathered under one factor, and this single factor explained 36.775% of the total variance. Results showed that when item-total correlation values of normal birth and caesarean section were examined, it was found that item-total correlation values of 16 items in the scale were between 0.407 and 0.759. When item scores were examined, it was determined that there was consistency between the items. This research has shown that the majority of female workers prefer to giving births by caesarean section, while there is no clinical indication and they are suggested to normal delivery. As a result of the established DFA model, the fit indexes of the model were found to be among the perfect fit values (x2/df=65.26/25≤3).Unnecessary caesarean delivery continues to be an increasingly important problem in the world. Thanks to the information and training provided with the right resources, it is possible to reduce the caesarean rates and increase the normal birth rates with the right choices. This study aimed to learn the opinions of female employees in Eskişehir family health centers about normal and caesarean births, to determine important points and develop suggestions for these methods. The population of the study was 170 working women. Factor analysis, 16 items normal birth, and caesarean delivery scale were gathered under one factor, and this single factor explained 36.775% of the total variance. Results showed that when item-total correlation values of normal birth and caesarean section were examined, it was found that item-total correlation values of 16 items in the scale were between 0.407 and 0.759. When item scores were examined, it was determined that there was consistency between the items. This research has shown that the majority of female workers prefer to giving births by caesarean section, while there is no clinical indication and they are suggested to normal delivery. As a result of the established DFA model, the fit indexes of the model were found to be among the perfect fit values (x2/df=65.26/25≤3)
The Effect of Effleurage Massage on Primary Dysmenorrhea in Female Adolescent Students
No full textPrimary dysmenorrhea is a painful condition during menstruation. It is characterized as cramping and is centered on the lower abdomen. The state may be accompanied by headaches, nausea, vomiting, diarrhea, and mild to severe trembling as it affects daily activities. The dysmenorrhea condition would affect the quality of life of most women. This study aimed to determine the effect of effleurage massage on primary dysmenorrhea of female adolescents in student’s dormitory of General Achmad Yani University, Yogyakarta. Method This research used a quasi-experimental approach with pre and post-test for two-group design. A total sample of 58 respondents was divided into the intervention and control groups. The sample determination used simple random sampling. Furthermore, the data is analyzed using the Wilcoxon test. Results this research showed a significant difference between the intervention groups and the control group was found after the intervention group was given the effleurage massage treatment (p <0.05). The conclusion of this research is effleurage massage has a significant effect on reducing pain in the lower abdomen during menstruation (dysmenorrhea). It is recommended to promote effleurage massage as an alternative to non-pharmacological treatment for female adolescents to reduce pain due to their dysmenorrhea.Primary dysmenorrhea is a painful condition during menstruation. It is characterized as cramping and is centered on the lower abdomen. The state may be accompanied by headaches, nausea, vomiting, diarrhea, and mild to severe trembling as it affects daily activities. The dysmenorrhea condition would affect the quality of life of most women. This study aimed to determine the effect of effleurage massage on primary dysmenorrhea of female adolescents in student’s dormitory of General Achmad Yani University, Yogyakarta. Method This research used a quasi-experimental approach with pre and post-test for two-group design. A total sample of 58 respondents was divided into the intervention and control groups. The sample determination used simple random sampling. Furthermore, the data is analyzed using the Wilcoxon test. Results this research showed a significant difference between the intervention groups and the control group was found after the intervention group was given the effleurage massage treatment (p <0.05). The conclusion of this research is effleurage massage has a significant effect on reducing pain in the lower abdomen during menstruation (dysmenorrhea). It is recommended to promote effleurage massage as an alternative to non-pharmacological treatment for female adolescents to reduce pain due to their dysmenorrhea
Characteristics and Antioxidant Activity of Sweet Potato Syrup (Ipomea Batatas (L) with Propylene Glycol Variation
No full textSweet Potato Leaf (Ipomea Batatas (L) contains flavonoids and polyphenols which play a role in antioxidant activity. Sweet Potato leaf extract is formulated into syrup because it is faster to be absorption compared to solid preparations and more easily to swallow. Sweet potato extract is formulated with variations in the amount of propylene glycol which is 11% (F1), 12% (F2), 13% (F3) and 0% (control). The characteristics of syrup include organoleptic tests, viscosity tests and time of flow were determine and syrup antioxidant activity testing using method 2 , 2-diphenyl-1-picrylhydrazyl (DPPH). Test results showed that all formulas have the same organoleptic properties, which are brown, sweet and slightly bitter. Weak antioxidant activity showed by IC50 and AAI values. IC50 and AAI syrup were 134 ± 19.28, 128 ± 4.04, 115 ± 13.07, and 142 ± 1.5 mg / mL and the AAI values were 0.074, 0.078, 0.087 and 0.070, respectively for F1, F2, F3 and control. Statistical analysis with the Kruskal-Wallis test (p> 0.05) showed no significant IC50 differences for the three formulas and control. The increase in propylene glycol affects the viscosity and ease of pouring but not the organoleptic properties while the antioxidant activity is not significantly different from the increase in propylene glycol. It is recommended to do a hedonic test for all three formulas in further research.Sweet Potato Leaf (Ipomea Batatas (L) contains flavonoids and polyphenols which play a role in antioxidant activity. Sweet Potato leaf extract is formulated into syrup because it is faster to be absorption compared to solid preparations and more easily to swallow. Sweet potato extract is formulated with variations in the amount of propylene glycol which is 11% (F1), 12% (F2), 13% (F3) and 0% (control). The characteristics of syrup include organoleptic tests, viscosity tests and time of flow were determine and syrup antioxidant activity testing using method 2 , 2-diphenyl-1-picrylhydrazyl (DPPH). Test results showed that all formulas have the same organoleptic properties, which are brown, sweet and slightly bitter. Weak antioxidant activity showed by IC50 and AAI values. IC50 and AAI syrup were 134 ± 19.28, 128 ± 4.04, 115 ± 13.07, and 142 ± 1.5 mg / mL and the AAI values were 0.074, 0.078, 0.087 and 0.070, respectively for F1, F2, F3 and control. Statistical analysis with the Kruskal-Wallis test (p> 0.05) showed no significant IC50 differences for the three formulas and control. The increase in propylene glycol affects the viscosity and ease of pouring but not the organoleptic properties while the antioxidant activity is not significantly different from the increase in propylene glycol. It is recommended to do a hedonic test for all three formulas in further research