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Perceived Stress During COVID-19 Pandemic: The Malaysian Nurses Experience
Research shows that nurses are one of the most vulnerable categories of professionals to develop stress and other problems due to the nature of their job. Thus the objective of this study is to describe the perceived stress experienced during the COVID-19 pandemic among Malaysian nurses. A cross-sectional study was conducted through an online form involving 319 randomly selected nurses from a teaching hospital on the east coast of Pahang, Malaysia, between January to December 2022. The perceived stress was measured using the Malay version 10-item Perceived Stress Scale, PSS-10 questionnaire. Descriptive and linear regression analysis was applied to measure the mean score of perceived stress and the association between perceived stress scores and other factors in this population. The study found that the total mean score of PSS-10 among the respondents was 19.1 ± 5.8. The three items with the highest mean scores were under the subscales “lack of self-efficiency” of the questionnaire (item-4, item-7, and item 5), while the item with the lowest mean scores belonged to subscales “perceived helplessness” (item-10). However, further analysis performed shows no significant association between perceived stress towards COVID-19 with sociodemographic and work-related factors among respondents. This study concluded that lack of self-efficiency was perceived as the main stress experienced by Malaysian nurses during the COVID-19 pandemic. Thus, it is pivotal that the nurse’s manager and higher authority of the organization focus on improving the efficiency of these nurses through targeted programs focusing on problem-solving, emotional and on-the -job management plan, along with accessibility to resources, a positive work environment and support
The Effect of Dayak Onion Extract (Eleutherine palmifolia (L.) Merr) on Swimming Time and Oxidative Stress Levels in Mice with the Forced Swimming Test Model
Excessive physical exercise can increase the occurrence of oxidative stress, which is characterized by cell damage caused by free radicals. Antioxidants found in Dayak Onion such as flavonoids, saponins, tannins, and vitamin C can be used as alternative ingredients to neutralize free radicals. The purpose of this study was to determine the effect of dose and duration of administration of Dayak onion extract on malondialdehyde (MDA) levels in a rat model of the forced gum test, extraction of Dayak onions using 96% ethanol. The type if research is Randomized Pre and Post Test Control Group Design. Male Sprague Dawley rats aged 2 months (weighing 150-200g) were divided into 5 groups: K- (control group, rats not given Dayak Onion extract but underwent forced swimming test), K+ (rats given xanthine and forced swimming test), P1 (rats given Dayak Onion extract at a dose of 50 mg/200 rats body weight/day), P2 (rats given Dayak Onion extract at a dose of 100 mg/200 rats body weight/day), P3 (rats given Dayak Onion extract at a dose of 200 mg/200 rats body weight/day). Dayak Onion extract was administered for 21 days with for 21 days with forced swimming test treatment, and changes in MDA levels were observed. The results showed that the administration of Dayak onion extract at a dose of 50 mg/200 rats/day, 100 mg/200 rats/day, and 200 mg/200 rats/day had an effect on preventing the increase in MDA, but at a dose of 200 mg/200 rats mice/day is the optimal dose. The conclusion is administration of Dayak Onion (Eleutherine palmifolia (L.) Merr) significantly decreased MDA levels in male Sprague Dawley rats with forced swimming test model
Difference of Cycle Threshold Value, Oxygen Saturation and D-dimer to COVID-19 Vaccination
Many factors can affect the prognosis of COVID-19 patients, and Cycle Threshold value can be used to estimate the amount of virus in the body. Oxygen saturation and D-dimer are important components in determining the severity. This study aims to analyze the difference of CT value, oxygen saturation, D-dimer, and degree of severity on vaccination state. This study is the observational analytic study of patients admitted to the isolation ward of a referral hospital in Surakarta, Indonesia. The analysis covered assessing the normality of the data, the Kruskal-Wallis correlation test, and ANOVA to assess the differences between variables. A total of 154 patients with, 65.6% of them did not participate in the full vaccination program. The results of the analysis showed a significant difference between the D-dimer and the degree of severity with a p-value of < 0.05, while the CT value and oxygen saturation had no significant difference with the vaccination state. Vaccination showed a significant difference with D-dimer and the degree of severity of COVID-19 infection, so giving a complete vaccine can reduce the severity of COVID-19 patients, and we recommended to be able to complete the vaccine for the whole community
Characteristics and Lifestyle Related to Blood Sugar Levels in Type 2 Diabetes Mellitus Patients
Type 2 diabetes mellitus has been a prominent public health issue today. Globally, an estimated 462 million people are affected by type 2 diabetes, equivalent to 6.28% of the world\u27s population. Globally, an estimated 462 million people are affected by type 2 diabetes, equivalent to 6.28% of the world\u27s population. In Asia, especially Indonesia, the number of cases is expected to increase to 21.3 by 2030 in Indonesia. Type 2 diabetes is determined by blood sugar level, which affected by many factors including patients’ characteristics and lifestyle habits such as physical activity and diet. The Purpose of this research is to find the association between age, sex, education level, employment status, duration of disease, obesity, hypertension, diet, and physical activity with the blood glucose level of type 2 diabetic patients. This research used cross-sectional study design. The population is type 2 diabetes mellitus patients The population is type 2 diabetes mellitus patients who are spread over three areas of the city of Makassar, at the city center, suburban health center and coastal health center, total sample size of 273 patients The research was conducted sampling for 2 months via interview. The research instruments used were IPAQ and FFQ. The data analysis technique used is univariate and bivariate analysis, using chi-square. The results of this study indicate that found correlation between the variables. Lifestyle were found associated most with blood sugar level. Findings of the research found association between duration (p=0.003), obesity (p=0.000), hypertension (p=0.048), diet (p=0.000), and physical activity (p=0.000) with blood sugar levels. Meanwhile, age (p=0.461), gender (p=0.431), education level (p=0.357), working status (p=0.522), found not associated with blood sugar levels in patients with type 2 diabetes. The conclusion is duration Obesity, hypertension, diet, and physical activity were found associated with blood glucose level in type 2 diabetic patients. Patients with type 2 diabetes are expected to maintain blood sugar level by implementing healthy lifestyle. This includes regular physical activity and balanced diet
Individual Health History, Body Mass Index, and Behavior as Causative Factors of Non-Communicable Diseases
Microorganisms do not cause non-communicable diseases (NCDs) but tend to change in modern lifestyles that do not apply CERDIK. In past research, the risk of suffering from non-communicable diseases was influenced by behavior, which consisted of three domains, namely knowledge, attitudes, and actions, without considering other individual factors. This study aims to assess the influence of individual health history factors, BMI, and behavior. The design used is cross-sectional. A sample of 302 people aged 15-59 are at risk of NCD and often visit fast food restaurants. Sampling using cluster random sampling. The variables collected are individual health history, BMI, and behavior. Data collection was carried out from April to June 2023. The analysis carried out was descriptive and structural equation modeling using PLS (Partial Least Square) software. The influence of the individual health history factor is 0.116, the BMI factor is 0.277, and the behavioral factor is -0.107. The resulting formula is . This formula can be used as a method to calculate the individual risk of suffering from NCDs
Factors Affecting Willingness to Pay for National Health Insurance Program among Informal Workers in Indonesia
The effort to achieve universal health coverage for all people under a single-payer national health insurance in Indonesia still experiences a substantial challenge particularly related to informal workers. This population faces a number of challenges, including income irregularity, a lack of educational variety, the fact that the majority of workers live in rural areas, and a lack of health insurance literacy. The objective of this study was to examine the factors that influence informal workers\u27 willingness to pay for a national health insurance program in Indonesia. This cross-sectional study was conducted in the Banyumas district of Central Java, Indonesia. Employing a multistage random sampling technique, 316 workers in the informal sector were recruited as study participants. Logistic regression was employed to investigate the factors that influence willingness to pay for national health insurance premiums. According to the study findings, urban, national health insurance information, and uneducated factors were related to informal workers\u27 willingness to pay for national health insurance. Workers who lived in urban area (p < 0.05, OR = 3.922) were more willing to pay for insurance premium. Workers who received better exposure of national health insurance information (p < 0.05, OR = 2.330) were more willing to pay for premium. Furthermore, workers who uneducated (p < 0.05, OR = 14.847) were more willing to pay for premium. The national health insurance campaign serves as a catalyst for increasing public awareness of this program. Adequate and widespread national health insurance program information dissemination would aid in the effectiveness of Indonesia\u27s efforts to achieve the goal of universal health insurance coverage
In Silico Analysis of the NPC1L1 Inhibitor of Catechins from Green Tea
The main contributor to cardiovascular disease is atherosclerosis. The Liver X Receptor is one of the unexplored signaling pathways in atherosclerosis that contributes to cholesterol efflux and inhibitory inflammation (LXR). Catechin, as an LXR agonist, influences the expression of the NPC1L1 protein transporter, which inhibits cholesterol absorption. The objective of this study is to predict the NPC1L1 inhibitor of Catechins from Green Tea. The role of NPC1L1 inhibitors is to prevent atherogenesis. Molecular docking is the research method used. Pyrx\u27s Open Babel was used for analysis. Autodock vina in Pyrx was employed for docking, and Chimera v1.8 was administered for visualization. The result of molecular interaction was assigned. Pose view was used in this study. Catechins have the potential to be an NPC1L1 inhibitor, according to the findings. The main parameters used to predict the biological effect were energy bonds, hydrogen bonds, and hydrophobic interactions of molecules with NPC1L1. All Catechins isolates had low affinity energy and a strong affinity for NPC1L1. Epigallocatechin gallate (EGCG) is the most effective inhibitor because it has the lowest binding energy and the most active sites, including Gln 200, Tyr 192, Trp 202, Cys 189, Gly 207, Asp 217, Gly 190, Phe 205, Asp 208. There are hydrogen bonds at Thr 219, Ile 218, Asn 204, Asn 211, Arg 201, and Asn 204. The interaction energy between NPC1L1 and EGCG is -7.5 kCal/mol. Based on the results of the in-silico analysis, the researchers concluded that Catechins have the potential to be an NPC1L1 inhibitor. Further research into molecular dynamic simulation and in vivo analysis is required to demonstrate the synergistic effect of Catechins as an inhibitor of atherogenesis
The Role of the Family in Preventing the Transmission of COVID-19 in Children
COVID-19 is a disease that is highly communicable from infected individuals to others who are susceptible to infection. The family is the first line of defense against the spread of the COVID-19 epidemic among youngsters. There is transmission of the COVID-19 virus to children notwithstanding the inadequacy of parental efforts to prevent such transmission. The effect of COVID-19 infection on unfit parents will result in the transmission of the virus to offspring. The incidence of COVID-19 in children is influenced by the level of parental knowledge and conduct to avoid the transfer of the virus. The purpose of this study is to examine the relationship between parents\u27 activities and attitudes regarding COVID-19 prevention, the detection of COVID-19 symptoms in children, and the level of information regarding the prevalence of COVID-19 in children. The research design employs a cross-sectional observational analysis. This study\u27s demographic and sample consisted of proportional samples from 12 Community Health Centers, with 550 family respondents in total. The results of this study indicate that delivering the COVID-19 vaccination to the family considerably reduces the risk of COVID-19 transmission to children. The level of family knowledge correlates strongly with the transmission of COVID-19 to children (a symp=0.001, with a correlation p-value of 0.669). There is a correlation between the administration of the COVID-19 vaccine to parents and the transmission of the virus to children (symp=0.001, p=0.660). Based on the results of the study, there was a significant influence between the level of parental knowledge on the behavior of preventing COVID-19 in children in Kupang City. In addition, there is a significant relationship between the behavior and attitudes of parents who are disobedient in preventing COVID-19 in children and the incidence of COVID-19 in children. Families or parents who carry out the COVID-19 vaccination in the family also have a significant relationship with the transmission of the COVID-19 virus to children. To reduce the transmission of COVID-19 to children, efforts from the family are needed, such as implementing health protocols and carrying out vaccinations.
The Effectiveness of Web-Based E-WoHealth on Compliance with Consumption of Iron Tablets in Young Women
Utilization of technological media in the field of education and health can increase public knowledge in efforts to prevent anemia, especially in young women. One of the efforts to prevent anemia and increase adherence to taking iron tablets is by using Web-based educational media (E-WoHealth) about iron tablets supplemented with a tablet supplement consumption control card. This research aims to develop Web-based E-WoHealth media and its effect on the level of adherence to the consumption of blood supplement tablets. This study used the Research and development (R&D) method with the Borg & Gall development model and the Pre-experimental Design quantitative method using the One Group Pretest-Postest approach. The sample in this study was 80 girls in grades VII and VIII of SMP Negeri 11 Gorontalo City, determined by purposive sampling technique. Statistical tests used the McNemar test and the Chi-Square test. The results of the McNemar test showed differences in the measurement results before and after being given the Web-based E-WoHealth media with a p-value of 0.000 <0.05 meaning that the Web-based E-WoHealth media was effective in increasing adherence to consumption of iron supplement tablets (TTD) in class VII and class VIII girls and the results of the Chi-Square P-Value test were 0.822 > 0.05 meaning that there was no difference in adherence between class VII and VII girls. This study recommends the application of WEB-based E-WoHealth media equipped with an iron supplement control card to increase adherence and monitor iron supplement consumption
Risk Factors Related to Stunting
Childhood stunting, or low height for age, continues to be a concern for world health since it raises the possibility of both mortality and growth and development disorders. West Kalimantan province ranks seventh with the highest prevalence of 29.8% by 2021. But little is known about Pontianak\u27s children\u27s stunting risk factors, especially in the UPT Puskesmas Pal Lima (one of the community health centers with a high prevalence of stunting). The study aimed to determine risk factors associated with stunting in the UPT Puskesmas Pal Lima, such as high-risk pregnant women, pregnant women with chronic energy deficiency, communication of educational information about stunting, occupancy density, and age of pregnant women in the UPT Puskesmas Pal Lima. Cross-sectional study design was used. The research was conducted in February-March 2023. The population in this study were all stunted toddlers in the UPT work area of the Pal Lima Health Center. Sampling used quota sampling with all 75 stunted toddlers. Data analysis used univariate and bivariate analysis (chi square test with 95% CI). This research found that 61,3% with high risk pregnant women, 21,3% with chronic energy deficiency, 52% not exposed to information communication and education about stunting, 32% occupancy density were not qualified, 48% risk at age of pregnant mothers, 32% severe stunting and 68% stunting. There was a significant relationship between high-risk pregnant women (p-value = 0,015), pregnant women with chronic energy deficiency (p-value = 0,001), the information communication and education about stunting (p-value = 0,046), occupancy density (p-value = 0,043), and the age of pregnant women (p-value = 0,049), and the incidence of stunting in toddlers in the working area of UPT Puskesmas Pal Lima, West Pontianak District. Based on the results of this study can be used as a basis for the primary prevention of stunting in pregnant women.