BIOLINK : Jurnal Biologi Lingkungan, Industri dan Kesehatan
Not a member yet
260 research outputs found
Sort by
ISOLATION AND SELECTION OF ENDOPHYTE FUNGI FROM THE ANDALIMAN PLANT (Zanthoxylum acanthopodium DC) AS ANTIFUNGAL
No full textDermatophytosis (Ringworm) is a disease caused by dermatophyte fungal infection that attacks the epidermis (keratin) tissue such as skin, nails and hair in humans. Antibiotics as a drug for fungal infections that are often used by the public are known to have side effects, so that alternative drugs are needed that are relatively safe to use. Endophytic microbes found in plants are known to be an alternative natural medicine that does not have side effects, because they contain bioactive compounds. This study aims to isolate, select and identify endophytic fungi in andaliman plants (Zanthoxylum acanthopodium DC) and determine their potential as antifungals against dermatophytosis fungi. Exploration methods were used, molecular analysis using marker genes Internal Transcribed Spacer (ITS) and antifungal activity tests (Dual culture) against Tricophyton rubrum and Tricophyton mentagrophytes as pathogenic test fungi. The results showed that endophytic fungus from the species Diaporthe phaseolorum (Isolate EF128). has very strong antifungal activity against the test fungus Tricophyton rubrum and is strong against Tricophyton mentagrophytes (isolate IJE D3). so it has the potential as an antifungal
STUDY OF PHYSICAL AND CHEMICAL CONTENT OF TEMPEH FACTORY LIQUID WASTE IN BEKASI DISTRICT
No full textThe tempeh industry in Indonesia is a traditional household industry. The production waste is generally discharged directly into water bodies without prior treatment. This study aims to identify the level of pollution caused by tempeh liquid waste physically and chemically. Analysis was carried out with laboratory tests to determine the levels of pH, TSS, BOD, COD, colour, and odour produced. This study was conducted at 3 large tempeh industries in Bekasi from January to April 2025. The results of laboratory tests showed that the chemical and physical parameters did not meet the quality standards of the Minister of Environment Regulation No. 5 of 2014. COD measurements found 1 point that did not meet the quality standards of 629.47 mg / l, TSS inlet 221 mg / l and TSS outlet 65 mg / l, the highest BOD 22.50 mg / l due to the addition of chemicals to tempeh to accelerate fermentation. This study uses inferential statistical analysis. The pH parameters for both the inlet and outlet are <6.5. Discharge of waste directly into rivers results in an unpleasant odour from fermented soybeans and organic matter. Tempeh wastewater is recommended for processing organic fertiliser or biogas from anaerobic fermentation
A STUDY ON THE QUALITY AND CHARACTERISTICS OF CPO FROM MIXED OUTSPEC SOURCES
No full textOutspec CPO is Crude Palm Oil (CPO) that does not meet standard CPO quality specifications. Outspec CPO can still be blended with standard CPO, provided that the resulting mixture continues to meet acceptable quality criteria. This study aimed to evaluate the effects of different blending levels of outspec CPO (0%, 1%, 3%, and 5%) and storage durations (0, 4, 8, and 12 days) on the quality of blended CPO. The research was conducted using an experimental method arranged in a factorial completely randomized design. The parameters measured to assess the quality of the blended CPO were: FFA (Free Fatty Acid), PV (Peroxide Value) and DOBI (Deterioration of Bleachability Index). The results showed that the highest quality was achieved with a 0% outspec CPO blend and 0 days of storage, yielding: FFA: 3.10%, PV: 0.10 meq/kg and DOBI: 2.97. Conversely, the lowest quality was observed with a 5% outspec CPO blend and 12 days of storage, resulting in: FFA: 5.31%, PV: 25.45 meq/kg and DOBI: 1.28. These findings indicate that a higher percentage of outspec CPO and longer storage durations lead to increased FFA and PV values, while the DOBI value decreases
ECO-FRIENDLY INNOVATION: POTENTIAL OF RED DRAGON FRUIT PEEL EXTRACT IN SILVER NANOPARTICLE BIOSYNTHESIS
No full textEast Kalimantan is one of the regions that cultivates red dragon fruit (Hylocereus polyrhizus) in large quantities due to its promising health benefits. The peel of red dragon fruit has antioxidant activity comparable to its flesh, yet it is rarely utilized and often discarded as organic waste. This study aims to explore the potential of water and ethanol extracts from red dragon fruit peel as antioxidant sources that can serve as natural reducing and stabilizing agents in the biosynthesis of silver nanoparticles (AgNPs). Extraction using water and ethanol solvents was conducted to analyze the antioxidant compounds in the peel. The extract with the strongest antioxidant activity was used for AgNP biosynthesis, and the absorption peak was observed using UV-Vis spectrophotometry at a specific wavelength of 400–450 nm, which is characteristic of AgNP surface plasmon resonance. The results showed that the ethanol extract exhibited stronger antioxidant potential based on its lower IC₅₀ value and functioned effectively as a reducing and stabilizing agent at synthesis temperatures of 40–50°C, without degrading the extract's secondary metabolites. These findings support the utilization of red dragon fruit peel as a sustainable and eco-friendly raw material for the development of health-related products
ANTIDIABETES TEST OF ETANOL EXTRACT OF ARA SUNGSANG LEAVES (Asystasia gangetica L.) ON ALOKSAN INDUCED WHITE MICE
Get PDFType 2 diabetes mellitus is caused by progressive impairment of insulin secretion leading to insulin resistance. Long-term use of antidiabetic drugs has gastrointestinal side effects as well as an increased risk of hypoglycemia. Therefore, a safer herbal treatment was developed. The purpose of the study was to determine the antidiabetic activity of ethanol extract of ara sungsang leaves on the reduction of glucose levels. The research is experimental, with the stages of making and standardizing simplisia, phytochemical screening, extraction, testing antidiabetic activity in vivo with 25 male mice. Blood glucose levels were determined at the beginning of fasting, after alloxan induction dose of 150 mg/kgbw, day 3, 6, 9, 12, 15. Blood glucose levels were analyzed statistically using the oneway ANOVA method. The results of the examination of simplisia standardization showed that the standardization of simplisia met the requirements. Phytochemical screening results showed that ara sungsang contains alkaloids, flavonoids, saponins, tannins, glycosides, and steroids/triterpenoids. The antidiabetic activity test in mice showed that the ethanol extract of ara sungsang at a dose of 225 mg/kgbw had a greater effect on reducing blood glucose levels than doses of 75 and 150 mg/kgbw
THE IMPROVEMENT OF CPO QUALITY USING PHYSICAL PURIFICATION MATERIAL OF SHELL POWDER FOR RED COOKING OIL PRODUCTION
No full textThe production of CPO (Crude Palm Oil) generated and utilized by the industry must consider market demand, prioritizing the quality of the final CPO product that complies with the SNI 01-2901-2021 standard. It includes free fatty acid (FFA) content, water, and impurities, with maximum limits of 5%, 0.25%, and 0.25%, respectively. Another parameter affecting CPO quality is the Deterioration of Bleachability Index (DOBI) value. This study investigates the potential use of calcium oxide (CaO) derived from seashells to improve CPO quality in the production of Red Cooking Oil (M3). The study design employed a Completely Randomized Design (CRD) with a non-factorial method. The treatment factor in this study was seashell powder heated at 600°C with varying concentrations: 0%, 1%, 2%, 3%, and 4%, as well as 1% Bleaching Earth commonly used at neutral pH (6-7 ). The treatments applied included K0 (no treatment), K1 (1% Bleaching Earth), K2 (1% Seashell Powder), K3 (2% Seashell Powder), K4 (3% Seashell Powder), and K5 (4% Seashell Powder) . The results showed that seashell powder significantly reduced free fatty acid content in K5 by 13.51%, decreased water content in K4 and K5 by 47.05%, and increased the DOBI value by 47.05%
SENSITIVITY OF BIOFILM-PRODUCING BACTERIA FROM NASOGASTRIC TUBES TO ANTIBIOTICS CEFTRIAXONE & CEFOBACTAM
Get PDFNasogastric Tube (NGT) is a common practice in medical care, especially for the administration of nutrients or drugs directly into the digestive tract. The surface of the NGT is in direct contact with the respiratory tract and digestive tract providing ideal conditions for bacteria to form biofilms. Biofilms have the ability to provide a high level of resistance to antimicrobial action and body defenses. Biofilms provide a microenvironment that protects bacteria from direct exposure to antimicrobial agents, such as antibiotics. This study aims to determine the sensitivity of biofilm-producing bacteria from NGT to antibiotics. This study used an experimental method conducted in the Pharmaceutical Microbiology Laboratory using purposive sampling techniques, biofilm detection using the Congo Red Agar and tube methods, Ceftriaxone and Cefobactam antibiotic sensitivity tests using the disc diffusion method. The results obtained that the positive Nasogastric Tube device can produce biofilm bacteria and can affect bacteria to become more resistant to antibiotics for long-term use of the Nasogastric Tube device. It can be seen that the measurement of the inhibition zone shows that the Ceftriaxone antibiotic has an average inhibition zone of 2.32 mm and Cefobactam 7.42 mm
THE EFFECT OF THE COMBINATION OF BAY LEAVES (Syzygium polyanthum) AND BREADFRUIT LEAVES (Artocarpus altilis) ON CHOLESTEROL LEVELS IN HYPERCHOLESTEROLEMIC MICE
Get PDFCentral Kalimantan has enormous natural resource potential, particularly in the area of medicinal plants such as bay leaves and breadfruit. Although, people in Central Kalimantan have utilized herbs as medicine, there has not been any scientific study done. This study aims to determine the effect of giving a combination of bay leaf and breadfruit leaf extracts in reducing cholesterol levels in Balb/c Hypercholesterolaemia mice. This study was conducted using the Mixed Method method, namely exploratory research and experimental research. The research subjects used were 28 female Balb/c mice in Hypercholesterolaemia conditions. In this study there were 7 treatments including positive control, negative control, P1 (20)%, P2 (30)%, P3 (40)%, P4 (50)%, P5 (60)% with 4 replications. The data analysis technique used in this study was One Way ANOVA. The finding of the study indicate that the combination of Bay Leaves and Breadfruit Leaves has an effect on reducing cholesterol levels in hypercholesterolemic mice, which can be seen from the p-value α (α 0.05) which is 0.000. Additionally, the most effective concentration in reducing cholesterol levels in hypercholesterolemic mice resulting in the concentration of P6 (50%) with a decrease of 60.25 Mg/dL
BIODIVERSITY OF ARACEAE IN MALABAR CITY FOREST, MALANG CITY, EAST JAVA
No full textIndonesia, located on the equator with over 17,000 islands, is among the world's most biodiverse countries. Malabar City Forest in Malang serves as both a green space and a habitat for various plant species, including members of the Araceae family. Despite their roles in microclimate regulation, air purification, and soil stabilization, Araceae diversity in urban areas remains underexplored. This study aimed to identify and document Araceae species in Malabar City Forest and assess their ecological roles. Using an exploratory survey and cruise sampling, species were recorded based on their morphology. Field data were collected through direct observation aided by smartphone-based identification tools and validated with online taxonomic resources and literatures. Seven species were identified: Dieffenbachia seguine (Jacq.) Schott, Epipremnum aureum (Linden & André) G.S Bunting, Alocasia plumbea Van Houtte, Syngonium angustatum Schott, Syngonium podophyllum Schott, Epipremnum pinnatum (L.) Engl., and Typhonium trilobatum Schott, representing six genera. Their presence highlights adaptability to urban environments and potential as bioindicators. Future research should assess their ecological resilience and interactions. Local conservation through education, labeling, and habitat preservation can support biodiversity awareness and sustainable urban planning
DIVERSITY OF MOSS PLANTS (BRYOPHYTA) IN COBAN TALUN, BATU CITY
Get PDFMosses (Bryophyta) are lower plants that lack the vascular tissue, roots, stems and true leaves of higher plants. Lichens can grow in a variety of habitats, including in extreme environments. This study aims to identify the diversity of moss plants in Coban Talun, Batu City, East Java. The sampling technique applied in this study involved dividing the area into 10 plots, with each plot having a size of 3m x 3m. The results obtained from ten plots in the Coban Talun waterfall area showed the presence of 9 species of lichens growing in the location, namely Anoectangium aestivum, Anomodon attenuatus, Campylopus introflexus, Marchantia polymorpha, L. cruciata, Pogonatum inflexum, Andreaea sp., Leucobryum glaucum, and Conocephalum conicum. Moss diversity is strongly influenced by environmental conditions such as temperature, air humidity, and light intensity. At low temperatures (around 25°C) moss diversity is higher than at higher temperatures (around 29°C). At humidity close to 72%, liverwort diversity is more dominant, while at humidity around 62%, leafwort diversity is more dominant