2172 research outputs found
Sort by
Synthesis, Crystallization, and Hydrolytic Degradation of Stereo Multiblock Poly(lactic acid)s
豊橋技術科学大学博士(工学)thesi
Retention Behavior of Pyrazines in Reversed-Phase High Performance Liquid Chromatography
豊橋技術科学大学博士(工学)doctoral thesi
Modeling of Brick Masonry Infill for Seismic Performance Evaluation of RC Frame Buildings
豊橋技術科学大学博士(工学)doctoral thesi
Validity for Measuring Blood CO Concentration by Head Space Method
P(論文)Carbon monoxide (CO) concentration in the blood is measured by a headspace
method with a gas-chromatography (HS-GC) and/or a CO-oximeter. However, the
deficiencies of using HS-GC, especially on blood CO analysis, are not well
documented. In the present study the effect of these deficiencies and the agreement
of the results between the HS-GC and CO-oximeter methods were examined. Results
indicated, in the application of HS-GC for blood CO analysis, that the TRIlyzer, a
simplified gas chromatograph used in this study, showed a high linearity and
reproducibility. The use of a surfactant such as Triton enhanced destruction of the
plasma membrane of the erythrocytes and thereby increased blood CO values.
Furthermore, an alkaline buffer solution provided higher blood CO values compared
with those of an acid buffer solution. Correlation analysis between the results obtained
by HS-GC and CO-oximeter on four subjects, including smokers and non-smokers,
also revealed a significant relationship (r= 0.954) between them. However, the
correlation coefficient (r) between CO concentrations during and after exercise
measured by HS-GC and CO-oximeter on each subject showed a negative correlation
for three of the four subjects. It is suggested that, in the application of HS-GC, a
surfactant and an alkaline buffer solution should be used in the blood CO analysis, but
discrepancies still remain between the values obtained by HS-GC and CO-oximeter.
Therefore, further studies will be required to obtain clear agreement between the
methods.departmental bulletin pape