209 research outputs found
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Interview with Steven C. Frautschi
Full text linkAn interview in two sessions with Steven C. Frautschi, professor of theoretical physics in the Division of Physics, Mathematics, and Astronomy. Dr. Frautschi discusses his family background and his early years in Madison, Wisconsin. He recalls matriculating, age 16, at Harvard, where his advisor was J. H. van Vleck; graduating in 1954 with an AB in physics, entering Stanford after a year spent bicycling around Europe on a Harvard traveling fellowship. At Stanford, under Sidney Drell, he and James Bjorken worked out the theory for an experiment being conducted by Nobel laureate Burton Richter. After receiving his PhD in 1958 he spent a postdoctoral year at Hideki Yukawa's Institute for Theoretical Physics in Kyoto, followed by a two-year postdoctoral stint at UC Berkeley, where he worked with Geoffrey Chew on Chew's "bootstrap" theory of strongly interacting particles and with Stanley Mandelstam on Regge poles. To Cornell in 1961. Invited to Caltech by Murray Gell-Mann; 1962 paper with Gell-Mann and Fred Zachariasen on Regge poles. Joins Caltech faculty as an assistant professor in the fall of 1962. Comments on the teaching of physics at Caltech in the early sixties; Gell-Mann and Richard P. Feynman; Gell-Mann's interest in linguistics.
Discusses his "statistical bootstrap" theory of the early 1970s for newly discovered strongly interacting particles. Discusses his 1982 paper in Science on the entropy of the observable universe. Discusses his work for The Mechanical Universe television project. Nine years as executive officer for physics, beginning in 1988; comments on the physics core curriculum and "take-home" labs. Comments on his work as master of student houses beginning in 1997, on the gradual "professionalization" of student affairs, and on his encouragement of the performing arts at Caltech
Interview with Ray David Owen
Full text linkInterview with Ray Owen, Professor of Biology at Caltech, conducted by Rachel Prud'homme in 1983. The interview covers Owen's early life growing up in Wisconsin, where he attended the University of Wisconsin, studying cattle genetics with C. Stormont; his early research on chimerism in twin calves and on immunological tolerance. In 1946 he joins the biology division faculty at Caltech in genetics as a Gosney Fellow. Recollections of genetics at Caltech following World War II: concurrent arrivals include G. W. Beadle, N. Horowitz, H. Mitchell, and L. DuBridge. Recalls T. H. Morgan's reputation and his colleagues A. H. Sturtevant and S. Emerson. Other members of the biology division at this time include C. Bridges, H. J. Muller, H. Borsook, A. Haagen-Smit, C. Wiersma, A. van Harrevelt, and F. Went. Recollections of L. Pauling. His book, General Genetics, with A. Srb published in 1952. His work with D. Lindsley on bone marrow transplantation. At Caltech, involvement with freshman admissions. In 1961 becomes biology division chair. Discusses teaching and further work in student affairs, including admission and recruitment of women, the Committee on the Freshman Year, and pass/fail grading. Appointment in 1975 to dean of students and vice-president for student affairs. Involvement with National Cancer Program (1972-1975) and continuing research on immunological tolerance. Concludes with observations on genetic engineering and safety of genetics research
Interview with Paul B. MacCready
Full text linkAn interview in three sessions with Paul B. MacCready, Caltech graduate (MS physics, 1948; PhD aeronautics, 1952) and inventor and entrepreneur who became internationally known in 1977 as the "father of human-powered flight." Conducted by Sara Lippincott, the oral history covers MacCready's scientific and entrepreneurial career, including biographical details. MacCready discusses his family life, early education and aeronautical interests in New Haven, CT. During his youth he progressed from the construction of model airplanes to the flying of motor-propelled aircraft and gliders. MacCready recounts his soaring competitions along with his education at Yale in the 1940s; he continues by describing his graduate work at Caltech from 1947 to 1952 and his high altitude soaring in the Sierras and Europe; he relates this to his interest in weather modification and his entrepreneurial work in cloud seeding.
In 1971 MacCready founded AeroVironment with his associates Peter Lissaman and Ivar Tombach; he discusses his early clients and research. Beginning in the mid-1970s MacCready began work on the celebrated Gossamer aircraft series; the interview includes discussion concerning the advent of the Gossamer Condor in 1976-1977 and the flight of the Gossamer Albatross across the English Channel in 1979. The interview also includes his continued interest in human-powered flight and environmental issues, as well as unmanned solar-powered flight
Interview with Edward B. Lewis
Full text linkA 1984 interview in two sessions with Edward B. Lewis, then the Thomas Hunt Morgan Professor of Biology at Caltech. Dr. Lewis would be awarded the 1995 Nobel Prize in physiology or medicine, along with Christiane Nüsslein-Vollhard and Eric F. Wieschaus, for discoveries concerning "the genetic control of early embryonic development." In this interview, he recalls how he and a colleague, Edward Novitski (who would also receive a Caltech PhD), acquired stocks of Drosophila melanogaster while they were still high school students in Wilkes-Barre, Pennsylvania. In 1939, after a year at Bucknell on a music scholarship and only two years at the University of Minnesota, Lewis received his bachelor's degree (in biostatistics), whereupon he entered Caltech as a graduate student. Working under A. H. Sturtevant, he continued his Drosophila studies, receiving his PhD in genetics in 1942. After a wartime stint as a meteorologist in the Army Air Forces, Dr. Lewis returned to Caltech as an instructor in the Division of Biology in 1946. He became a full professor in 1956 and the Morgan Professor in 1966.
He recalls the early days of genetics at Caltech and offers his recollections of Thomas Hunt Morgan, chair of the division from 1928 to 1942, and of Sturtevant and Theodosius Dobzhansky. He comments on the state of the Biology Division after Morgan's retirement and on the arrival of George W. Beadle as division chairman in 1946. He describes his work on the Drosophila bithorax complex of genes and also on the somatic effects of radiation on human beings and his part in the controversy over nuclear testing in the late 1950s and early 1960s. He recalls the visit of four geneticists from the Soviet Union in 1967. He concludes by commenting briefly on the changes in the field of genetics since the discovery of the genetic material and on his current work on the phenomenon of transvection.
Dr. Lewis became emeritus in 1988 and died on July 21, 2004
Interview with William J. Dreyer
Full text linkAn interview in five sessions in 1999 with William J. Dreyer, molecular immunologist and Caltech professor of biology (1963-2004). He begins with a discussion of how some people think visually, himself included--a theme to which he returns repeatedly in the interview. He speaks of his family history: childhood in Michigan and Wisconsin; his Norwegian father and possible inherited family traits including dyslexia and mental imaging. Recalls his education at Reed College in Oregon (BA chemistry, 1952) and graduate study at University of Washington (PhD in biochemistry, 1956); works under H. Neurath at UW. First occurrence of cancer while in graduate school. He goes to National Institutes of Health (NIH) as a National Polio Foundation postdoc, where he works on proteins with C. Anfinsen; becomes research scientist at NIH; assists M. Nirenberg in work on genetic code. Meets and works with G. Streisinger on genetic mapping with phage. Still at NIH begins inventing machinery for automating biochemical analyses.
Recruited to Caltech and accepts appointment in biology division in 1963. Together with J. Claude Bennett writes major papers on genetic coding for protein structure, gene splicing and monoclonal antibodies. Recalls Leroy Hood's arrival at Caltech in 1963 as grad student. Dreyer's consulting work for Spinco division of Beckman Instruments; helps in the design of an automated protein sequencer; his continuing interest in new technologies. Work in 1960s with W. Gray on sequencing protein in a mass spectrometer for JPL; collaborates with Gray and Hood on 1967 Cold Spring Harbor symposium paper on antibody formation. Roger Sperry at Caltech; his influence on Dreyer. Work on the protein rhodopsin. Robert Sinsheimer as biology division chairman. During 1970s and 80s Caltech develops series of more and more sensitive instruments to synthesize and analyze genes and proteins. 1982 recurrence of Dreyer's cancer. Creation of company Applied Biosystems with Hood and M. Hunkapiller; issues arise over patents and royalties. Dreyer's work with Milton Wexler's Hereditary Disease Foundation. Caltech's Beckman Institute; recruitment of Scott Fraser and creation of Biology Imaging Center at Caltech. Study of olfactory receptors; "area code" hypothesis in embryogenesis. Capillary electrophoresis; the Human Genome Project. Recent experiments involving gene deletion and DNA alteration
Interview with Melvin I. Simon
Full text linkInterview in two sessions, May 24 and June 5, 2005, with Melvin I. Simon, Anne P. and Benjamin F. Biaggini Professor of Biological Sciences, emeritus, in the Division of Biology.
Dr. Simon received his BS from City College of New York in 1959 and his PhD in biochemistry from Brandeis in 1963. After receiving his degree, he was a postdoctoral fellow with Arthur Pardee at Princeton for a year and a half and then joined the faculty of the University of California at San Diego. In 1978, Dr. Simon and his UCSD colleague John Abelson established the Agouron Institute in San Diego, focusing on problems in molecular biology. He (along with Abelson) joined the faculty of Caltech as a full professor in 1982, and he served as chair of the Biology Division from 1995 to 2000.
In this interview, he discusses his education in Manhattan’s Yeshiva High School (where science courses were taught by teachers from the Bronx High School of Science), at CCNY, and as a Brandeis graduate student working working with Helen Van Vunakis on bacteriophage. Recalls his unsatisfactory postdoc experience at Princeton and his delight at arriving at UC San Diego, where molecular biology was just getting started. Discusses his work on bacterial organelles; recalls his and Abelson’s vain efforts to get UCSD to back a full-scale initiative in molecular biology and their subsequent founding of their own institute. Recalls his early years at Caltech and the domination of the Biology Division by Leroy E. Hood, who was developing molecular sequencing machines. Recalls the establishment of the Beckman Institute. Discusses his growing interest in genomics and his involvement with the Human Genome Project. Discusses the departure of division chairman Lee Hood, the subsequent chairmanship of Abelson, and his own stint as chairman. Recalls the recruiting and arrival of David Baltimore as Caltech’s president (1997-2007) and assesses his presidency
Interview with Victor Wouk
Full text linkThis wide-ranging interview in May 2004 with the engineer and hybrid-automobile pioneer Victor Wouk begins with his recollections of his graduate work in electrical engineering at Caltech (1939-1942), after receiving his bachelor's degree from Columbia. Includes recollections of Robert A. Millikan, Royal Sorensen, William H. Pickering, William R. Smythe, Frederick C. Lindvall, and others. He recalls his wartime work at the Westinghouse Research Laboratories in Pittsburgh on the ignitron and the separation of uranium isotopes. Also recalls his early interest in television and work for North American Philips in Tarrytown, NY. Forms the Electronic Energy Conversion Corp. in 1959 to manufacture DC power units. Recalls work for Motorola founder Russell Feldman, who in the early 1960s asked him to design a practical electrically powered car; eventually, in consultation with Lee A. DuBridge and others at Caltech, Wouk determined that a hybrid vehicle, using both electric power and traditional combustion, was a better alternative. Studies were revealing the detrimental effects of smog in the nation's cities, and in 1970 the Clean Air Act passed. Wouk had meanwhile sold the Electronic Energy Conversion Corp. to Gulton Industries and gone to work for them; he left, along with Gulton's Charles Rosen, to form a new company, Petro-Electric Motors, to develop a hybrid vehicle for the Federal Clean Car Incentive Program in the early 1970s. He recalls in detail their travails and eventual success, and comments on the opposition of Eric Stork at the Environmental Protection Agency to the hybrid idea, which finally resulted in rejection of his model. He concludes the interview by commenting on the recent history, current popularity, and future of hybrid cars, and on his ideas about regenerative braking
Interview with William B. Bridges
Full text linkAn interview in three sessions, in May and June 2001, and an Addendum, March 2004, with William B. Bridges, Carl F. Braun Professor of Engineering in the Division of Engineering and Applied Science. Dr. Bridges received his undergraduate and graduate education at the University of California at Berkeley (BS in electrical engineering, 1956; MS, 1957; PhD, 1962). At Berkeley in graduate school, he worked with John Whinnery and Charles K. (Ned) Birdsall on microwave vacuum tubes. He recalls that work and comments on its military applications. He then went to Hughes Research Laboratories (now HRL Laboratories LLC), for which he still is a consultant. Recalls gas laser work in the early 1960s at HRL and Bell Laboratories and the development of the argon-ion laser. In 1977 he joined the Caltech faculty with a joint appointment in electrical engineering and applied physics, while continuing to consult at Hughes. At Caltech he began working on laser isotope separation and later on far-infrared lasers. He discusses his various graduate students in electrical engineering; his colleagues John Pierce, Hardy Martel, Robert Cannon, Roy Gould, and Sverre Eng; his part in developing an undergraduate option in electrical engineering and in building up that department; his work as executive officer for electrical engineering (1978-1981). Recalls his visiting professorship at the University of Göteborg, Sweden, summer 1989; technical advisor and board member of Uniphase Corporation, a fiber-optic-communications company (now JDS Uniphase) in the 1980s and 1990s. Comments on the difficulties faced by women in engineering and his establishment of a chapter of the Society of Women Engineers at Caltech. Discusses his involvement with Caltech's Program in Advanced Technologies in partnership with TRW, Aerojet, General Motors, and GTE. Concludes the interview with his recollections of Caltech President Marvin L. (Murph) Goldberger's attempt to set up a study center at the Jet Propulsion Laboratory for the U.S. Army (the Arroyo Center) and his recollections of Goldberger's successor as president, Thomas E. Everhart, whom Bridges knew from Hughes and Berkeley.
The Addendum to the interview concerns Bridges's marriage to Linda J. McManus
Interview with Donald E. Osterbrock
Full text linkIn this brief interview, the American astronomer Donald Osterbrock, who died on January 11, 2007, offers recollections of Enrico Fermi and Subrahmanyan Chandrasekhar in the early 1950s at the University of Chicago. He recalls the atmosphere at Yerkes Observatory, where he got his PhD (1952); his postdoctoral fellowship at Princeton (1952-1953); and the five years he spent at Caltech, first as an instructor (1953-1955) and then as an assistant professor (1955-1958). At Caltech, he worked on gaseous nebulae. He recalls that work and comments on Jesse Greenstein's style as head of the astronomy department. He discusses his various colleagues affiliated with the Carnegie Observatories on Santa Barbara Street in Pasadena, including Walter Baade, Rudolph Minkowski, Armin Deutsch and Maarten Schmidt; his Caltech colleagues Guido Münch, Art Code, and Fritz Zwicky; his two graduate students, George Abell and John Mathis; his decision to leave Caltech in 1958 and help Art Code develop a graduate program in astronomy at the University of Wisconsin