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اطلاعات کتابشناختی مقالات منتشرشده دانشگاه علوم پزشکی بوشهر در پایگاه Scopus
No full textفایل اکسل حاوی اطلاعات کتابشناختی مقاله های منتشرشده با وابستگی سازمانی دانشگاه علوم پزشکی بوشهر در پایگاه استنادی اسکوپوس
مشتمل بر 670 عنوا
Assessment of health risk and burden of disease induced by exposure to benzene, toluene, ethylbenzene, and xylene in the outdoor air in Tehran, Iran
No full textThe health risk and burden of disease induced by exposure to benzene, toluene, ethylbenzene, and xylene (BTEX) in the outdoor air in Tehran, 2019 were assessed based on the data of five fixed stations with weekly BTEX measurements. The non-carcinogenic risk, carcinogenic risk, and disease burden from exposure to BTEX compounds were determined by hazard index (HI), incremental lifetime cancer risk (ILCR), and disability-adjusted life year (DALY), respectively. The average annual concentrations of benzene, toluene, ethylbenzene, and xylene in the outdoor air in Tehran were 6.59, 21.62, 4.68, and 20.88 μg/m3, respectively. The lowest seasonal BTEX concentrations were observed in spring and the highest ones occurred in summer. The HI values of BTEX in the outdoor air in Tehran by district ranged from 0.34 to 0.58 (less than one). The average ILCR values of benzene and ethylbenzene were 5.37 × 10-5 and 1.23 × 10-5, respectively (in the range of probable increased cancer risk). The DALYs, death, DALY rate (per 100,000 people) and death rate (per 100,000 people) induced by BTEX exposure in the outdoor air in Tehran were determined to be 180.21, 3.51, 2.07, and 0.04, respectively. The five highest attributable DALY rates in Tehran by district were observed in the districts 10 (2.60), 11 (2.43), 17 (2.41), 20 (2.32), and 9 (2.32), respectively. The corrective measures such as controlling road traffic and improving the quality of vehicles and gasoline in Tehran could reduce the burden of disease from BTEX along with the health effects of other outdoor air pollutants
Design and psychometric analysis of the safety harness usability and comfort assessment tool (SH UCAT)
Full text linkwhether deferoxamine (DFO) can prevent acute cardiotoxicity in children with cancer who were treated with DOX as part of their chemotherapy. Results: Sixty-two newly-diagnosed pediatric cancer patients aged 2–18 years with DOX as part of their treatment regimens were assigned to three groups: group 1 (no intervention, n = 21), group II (Deferoxamine (DFO) 10 times DOX dose, n = 20), and group III (DFO 50 mg/kg, n = 21). Patients in the intervention groups were pretreated with DFO 8-h intravenous infusion in each chemotherapy course during and after completion of DOX infusion. Conventional and tissue Doppler echocardiography, serum concentrations of human brain natriuretic peptide (BNP), and cardiac troponin I (cTnI) were checked after the last course of chemotherapy. Sixty patients were analyzed. The level of cTnI was < 0.01 in all patients. Serum BNP was significantly lower in group 3 compared to control subjects (P = 0.036). No significant differences were observed in the parameters of Doppler echocardiography. Significant lower values of tissue Doppler late diastolic velocity at the lateral annulus of the tricuspid valve were noticed in group 3 in comparison with controls. By using Pearson analysis, tissue Doppler systolic velocity of the septum showed a marginally significant negative correlation with DOX dose (P = 0.05, r = − 0.308). No adverse effect was reported in the intervention groups. Conclusions: High-dose DFO (50 mg/kg) may serve as a promising cardioprotective agent at least at the molecular level in cancer patients treated with DOX. Further multicenter trials with longer follow-ups are needed to investigate its protective role in delayed DOX-induced cardiac damage. Trial registration IRCT, IRCT2016080615666N5. Registered 6 September 2016
Photodegradation of ibuprofen laden-wastewater using sea-mud catalyst/H2O2 system: evaluation of sonication modes and energy consumption
No full textThe main goal of the current investigation was to decontaminate ibuprofen (IBP) from hospital wastewater using sea mud as an H2O2 activator. Sea sludge was converted into catalysts at different temperatures and residence times in furnaces, and then tested in the removal of IBP, and the most efficient ones were reported for the production of catalysts. The catalyst was optimized at 400 °C and 3 h. SEM-mapping, FTIR, EDX, BET, and BJH experiments were used to characterize the catalyst. Experiments were done at two pulsed and continuous ultrasonication modes in a photoreactor, and their efficiencies were statistically compared. The designed variables included IBP concentration (10–100 mg/L), the catalyst concentration (0–3 g/L), pH (4–9), and time (10–90 min). The oxidation process had the maximum efficiency at pH 4, treatment time of 60 min, catalyst quantity of 5 g/L, and IBP content of 50 mg/L. The catalyst was recycled, and in the fifth stage, the removal efficiency of IBP was reduced to 50%. The amount of energy consumed for treating IBP laden-wastewater using the evaluated catalyst in two modes of continuous and pulsed ultrasonic was calculated as 102 kW h/m3 and 10 kW h/m3, respectively. IBP oxidation process was fitted with the first-order kinetic model. The system can be proposed for purifying hospital and pharmaceutical wastewaters. © 2022, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature
A comparative monitoring of maternal and cord serum polychlorinated biphenyls levels from Iranian pregnant women between industrial and urban areas
No full textThe aim of this study was to compare maternal and fetal exposure to PCBs in pregnant women from a petrochemical and gas area (PGA) and an urban area (UA), by the analyses of serum samples from mother (MS) and cord (CS). After liquid-liquid extracting, samples were analyzed for 12 PCBs congeners by gas chromatography mass spectrometer. Adjusted multiple linear regression models showed the mean levels (μg/L) of total PCBs in the MS and CS samples from the PGA (1.70 ± 0.81 and 1.19 ± 0.43) were significantly higher than those from UA (1.64 ± 0.75 and 1.07 ± 0.38). PCB 44 was predominant in both MS and CS serum samples, and in both PGA (0.80 ± 0.70 and 0.76 ± 0.67) and UA (0.79 ± 0.39 and 0.67 ± 0.34). A negative correlation was found for PCB 52 as one-unit increase in the cord serum levels was associated with 0.024 g decrease in newborn weight. Similarly, one-unit increase in the maternal serum PCB 18 concentrations were associated with 0.09 and 0.086 cm decrease in newborn height and head circumference. The serum levels of PCB 18 and 52 in the mothers who consumed meat and milk at least 1 meal/week were higher than these who consumed meat and milk never or less than 1 meal/month. The findings in this study indicated that higher maternal exposure to PCBs, as result of living in an industrialized area, leads to higher PCBs accumulation in cord blood, which consequently passes to the developing fetus. These events may cause harmful effects on both them in-utero and afterbirth growth and development. © 2022 Elsevier Lt
Opium use and risk of lung cancer: A multicenter case-control study in Iran
No full text(7.4, 95% CI: 3.8, 14.5) than in males (3.3, 95% CI: 2.6, 4.2). The OR for users of both opium and tobacco was 13.4 (95% CI: 10.2, 17.7) compared to nonusers of anything. The risk of developing lung cancer is higher in regular opium users, and these results strengthen the conclusions on the carcinogenicity of opium. The association is stronger for small cell carcinoma cases than in other histology. © 2022 UICC
بررسی سلامت عمومی پزشکان و اعضاء هییت علمی دانشگاه علوم پزشکی بوشهر و ارتباط آن باعوامل مختلف(میزان کار-میزان تفریحات)بروش انالیز رگرسیون لجستیک، در سال 92
No full textمقايسه اثر فراگمين با هپارين بر روی ليپيدهای سرم در طی 9 ماه در بيماران همودياليزی بيمارستان پانزده خرداد تهران
No full textزمينه و هدف: لخته شدن خون در طی همودياليز، عامل از دست رفتن خون و تداخل با کليرنس محلول دياليز است، از اين رو معمولاً در طول همودياليز، برای جلوگيری از لخته شدن خون، از هپارين استفاده میشود. هدف از اين مطالعه، بررسی اثرات هپارين و مقايسه آن با نوعی هپارين با وزن مولکولی پايين به نام فراگمين بر روی ليپيدهای سرم است. روش بررسی: مطالعه حاضر يک مطالعه تحقيقی ـ تجربی است که بر روی 2 گروه از بيماران همودياليزی انجام گرفته است. گروه اول شامل 11 بيمار(5 مرد و 6 زن) با ميانگين سنی 5/62 سال بود که به طور متوسط 8/76 ماه در مرکز دياليز بيمارستان پانزده خرداد دياليز شدند. همه بيماران مورد مطالعه، هپارين را با دوز يکسان دريافت کردند. گروه دوم نيز شامل 11 بيمار(5 مرد و 6 زن) با ميانگين سنی 6/55 سال بود که به طور متوسط 8/80 ماه در همان مرکز تحت همودياليز قرار داشتند و حدود 9 ماه، به طور مستمر فراگمين را با دوز يکسان دريافت کردند. هيچ يک از بيماران دو گروه، هرگز داروی کاهش دهنده چربی خون مصرف نکرده بودند. در زمانهای صفر، 3، 6 و 9 ماه، برای تمام بيماران آزمايشات کلسترول، تریگليسريد، HDL(High density lipoprotein) و LDL(Low density lipoprotein) درخواست شد. با فرض بر اينکه فراگمين عوارض هيپرليپيدمی ناشی از هپارين را ندارد، بيماران مصرف کننده هپارين، به عنوان گروه شاهد و بيماران مصرف کننده فراگمين، به عنوان گروه آزمايشی مورد بررسی قرار گرفتند. در آناليز نهايی از آزمون T Test استفاده شد. يافتهها: يافتهها نشان دادند که تفاوت معنیداری در ميزان کلسترول سرم بين دو گروه دريافت کننده هپارين و فراگمين وجود ندارد(59/0=p)، در خصوص تریگليسريد نيز تفاوت معنیداری بين دو گروه مذکور ديده نشد(18/0=p)، يافتههای اخير در مورد سطوح LDL و HDL نيز صادق بوده است(به ترتيب 74/0=p و 09/0=p). نتيجهگيری: نتايج بدست آمده حاکی از يکسان بودن اثر داروهای هپارين و فراگمين بر روی ليپيدهای سرم میباشد
External validation of the DHAKA score and comparison with the current IMCI algorithm for the assessment of dehydration in children with diarrhoea: a prospective cohort study
No full textBackground Dehydration due to diarrhoea is a leading cause of child death worldwide, yet no clinical tools for
assessing dehydration have been validated in resource-limited settings. The Dehydration: Assessing Kids Accurately
(DHAKA) score was derived for assessing dehydration in children with diarrhoea in a low-income country setting. In
this study, we aimed to externally validate the DHAKA score in a new population of children and compare its accuracy
and reliability to the current Integrated Management of Childhood Illness (IMCI) algorithm.
Methods DHAKA was a prospective cohort study done in children younger than 60 months presenting to the
International Centre for Diarrhoeal Disease Research, Bangladesh, with acute diarrhoea (defi ned by WHO as three or
more loose stools per day for less than 14 days). Local nurses assessed children and classifi ed their dehydration status
using both the DHAKA score and the IMCI algorithm. Serial weights were obtained and dehydration status was
established by percentage weight change with rehydration. We did regression analyses to validate the DHAKA score
and compared the accuracy and reliability of the DHAKA score and IMCI algorithm with receiver operator
characteristic (ROC) curves and the weighted κ statistic. This study was registered with ClinicalTrials.gov, number
NCT02007733.
Findings Between March 22, 2015, and May 15, 2015, 496 patients were included in our primary analyses. On the basis
of our criterion standard, 242 (49%) of 496 children had no dehydration, 184 (37%) of 496 had some dehydration, and
70 (14%) of 496 had severe dehydration. In multivariable regression analyses, each 1-point increase in the DHAKA
score predicted an increase of 0·6% in the percentage dehydration of the child and increased the odds of both some
and severe dehydration by a factor of 1·4. Both the accuracy and reliability of the DHAKA score were signifi cantly
greater than those of the IMCI algorithm.
Interpretation The DHAKA score is the fi rst clinical tool for assessing dehydration in children with acute diarrhoea to
be externally validated in a low-income country. Further validation studies in a diverse range of settings and paediatric
populations are warranted