Institute of Tropical Medicine Antwerp

Tropmed Central Antwerp
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    6320 research outputs found

    Defending the right to health for all; a vision of social protection

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    Bovine fasciolosis in the human fasciolosis hyperendemic Binh Dinh province in Central Vietnam

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    A cross-sectional survey on bovine fasciolosis was conducted in the Binh Dinh province of Central Vietnam that was previously identified as hyperendemic for human fasciolosis. In Vietnam, both pure Fasciola gigantica and hybrid and/or introgressed populations of liverflukes bearing genetic material from both Fasciola hepatica and F. gigantica infect humans and animals. In this study, 825 cattle were randomly selected from 8 of the 11 provincial districts for faecal collection; blood samples were taken from 400 of these animals. Fasciola eggs and antibodies against Fasciola were detected by a quantitative sedimentation method and an enzyme linked immunosorbent assay, respectively. Overall, 54.9% of the animals were shedding Fasciola eggs while 72.2% were Fasciola seropositive. Animals under two years showed lower Fasciola infection rates than older animals. There were no differences in infection rates between districts. These results indicate a very high prevalence of Fasciola infections in cattle in Binh Dinh province. It is concluded that a fasciolosis control programme should be designed in this region aiming at reducing infection in both cattle and humans

    Functional analysis of the Twin-Arginine Translocation Pathway in Sodalis glossinidius, a bacterial symbiont of the tsetse fly

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    This study demonstrates a functional twin-arginine (TAT) translocation pathway present in the tsetse fly symbiont Sodalis glossinidius and its potential to export active heterologous proteins to the periplasm. Functionality was demonstrated using green fluorescent protein (GFP) fused to the Tat signal peptide of E. coli trimethylamine N-oxide reductase (TorA)

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