12244 research outputs found
Sort by
A cross-sectional examination of the mental wellbeing, coping and quality of working life in health and social care workers in the UK at two time points of the COVID-19 pandemic
Get PDFAs the COVID-19 pandemic continues to evolve around the world, it is important to examine its effect on societies and individuals, including health and social care (HSC) professionals. The aim of this study was to compare cross-sectional data collected from HSC staff in the UK at two time points during the COVID-19 pandemic: Phase 1 (May–July 2020) and Phase 2 (November 2020–January 2021). The HSC staff surveyed consisted of nurses, midwives, allied health professionals, social care workers and social workers from across the UK (England, Wales, Scotland, Northern Ireland). Multiple regressions were used to examine the effects of different coping strategies and demographic and work-related variables on participants’ wellbeing and quality of working life to see how and if the predictors changed over time. An additional multiple regression was used to directly examine the effects of time (Phase 1 vs. Phase 2) on the outcome variables. Findings suggested that both wellbeing and quality of working life deteriorated from Phase 1 to Phase 2. The results have the potential to inform interventions for HSC staff during future waves of the COVID-19 pandemic, other infectious outbreaks or even other circumstances putting long-term pressures on HSC systems
How shall we address the Learning Sciences in ITE?
Get PDFThis document is an outcome of the project 'The Learning Sciences in Initial Teacher Education' based at Bath Spa University (2019-2020) and funded by the Wellcome Trust.
Cognitive psychology and neuroscience don’t provide definitive answers to complex educational questions. We see them as offering new information, frameworks and perspectives that should be examined in relation to other educational ideas and aims. We take a positive view of the new possibilities for understanding learning: research from the learning sciences could extend existing ideas or offer different kinds of explanations. If in this process contradictions appear we can and should use that as a provocation for debate. Initial Teacher Education (ITE) could play a key role in this through the ways in which we position research, literature and theory in the curriculum and discuss it with trainee teachers. In this document we share our experience of curriculum development within a Primary PGCE course
"Straight away I was aware that I was black": narratives from black mothers in and after prison
No full text
Appropriations of Rāvaṇa in political activism and reinventing mythic history: Indian cultural and religious ideas influencing contemporary Sri Lanka
No full textRemarkably capable, creative children [blog post]
No full textDr Karen McInnes talks about the value of play and playfulness and its role in communicating and learning creatively
Kauri tree‐ring stable isotopes reveal a centennial climate downturn following the Antarctic Cold Reversal in New Zealand
Get PDFThe dynamics of the Late Glacial (LG) have been demonstrated by numerous records from the Northern Hemisphere (NH) and far fewer from the Southern Hemisphere (SH). SH paleoclimate records reveal a general warming trend, interrupted by a deglaciation pause (ACR: Antarctic Cold Reversal, ∼14,700 – 13,000 cal BP). Here we present decadal tree‐ring stable isotope chronologies (δ18O, δ13C) from New Zealand (NZ) subfossil kauri trees (n=6) covering the post‐ACR millennium from 13 020 – 11 850 cal BP. We find a distinct, simultaneous downturn (∼12 625 – 12 375 cal BP) in all tree‐ring proxies paralleling regional tree growth declines, suggesting a widespread climate deterioration. This downturn was characterised by sustained high precipitation, low temperatures and high relative humidity in NZ with incoming weather fronts from the South Ocean. Despite these promising results, questions remain about what drove the Kauri Downturn and how the hydroclimatic conditions were altered during this time period
In utero exposure to dexamethasone causes a persistent and age-dependent exacerbation of the neurotoxic effects and glia activation induced by MDMA in dopaminergic brain regions of C57BL/6J mice
No full textClinical and preclinical evidence indicates that prenatal exposure to glucocorticoids may induce detrimental effects in the offspring, including reduction in fetal growth and alterations in the CNS. On this basis, the present study investigated whether in utero exposure to high levels of glucocorticoids is a risk factor that may lead to an exacerbation of the central noxious effects induced by psychoactive drugs consumed later in life. To this end, pregnant C57BL6/J dams were treated with dexamethasone (DEX, 0.05 mg/kg per day) from gestational day 14 until delivery. Thereafter, the male offspring were evaluated to ascertain the magnitude of dopaminergic damage, astrogliosis and microgliosis elicited in the nigrostriatal tract by the amphetamine-related drug 3,4-methylenedioxymethamphetamine (MDMA, 4 × 20 mg/kg, 2 h apart, sacrificed 48 h later) administered at either adolescence or adulthood. Immunohistochemistry was performed in the substantia nigra pars compacta (SNc) and striatum, to evaluate dopaminergic degeneration by measuring tyrosine hydroxylase (TH), as well as astrogliosis and microgliosis by measuring glial fibrillary acidic protein (GFAP) and ionized calcium-binding adapter molecule 1 (IBA-1), respectively. Moreover, immunohistochemistry was used to ascertain the co-localization of IBA-1 with either the pro-inflammatory interleukin (IL) IL-1β or the anti-inflammatory IL IL-10, in order to determine the microglial phenotype. In utero administration of DEX induced dopaminergic damage by decreasing the density of TH-positive fibers in the striatum, although only in adult mice. MDMA administration induced dopaminergic damage and glia activation in the nigrostriatal tract of adolescent and adult mice. Mice exposed to DEX in utero and treated with MDMA later in life showed a more pronounced loss of dopaminergic neurons (adolescent mice) and astrogliosis (adolescent and adult mice) in the SNc, compared with control mice. These results suggest that prenatal exposure to glucocorticoids may induce an age-dependent and persistent increase in the susceptibility to central toxicity of amphetamine-related drugs used later in life