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Time-averaging and stratigraphic resolution in death assemblages and Holocene deposits: Sydney harbour’s molluscan record
No full textTime-averaging has evolved from an unrecognized variable in paleoecological analyses to a key concept in understanding the dynamics of sedimentary systems and the formation of fossil deposits. Here we used radiocarbon-calibrated amino acid racemization ages from 173 Fulvia tenuicostata shells collected from Sydney Harbour (NSW, Australia) to quantify time-averaging in surficial and excavated death assemblages. A novel approach to estimating the total age-estimate variability of a collection of specimens is presented that integrates the age-estimation error associated with the AAR calibration model and the effect of time-averaging variability on the age distribution. Fulvia collected from a single 1.6-m deep excavation were used to quantify changes in time-averaging with burial depth. Fulvia collected from surficial death assemblages at six sites were used to quantify spatial variation in time-averaging. The median shell age increased from ∼ 150 yr to ∼ 4230 yr and time-averaging from ∼ 40 yr to ∼ 960 yr with increased burial depth. While four sites contained surface shell assemblages with median ages of ∼ 150 yr and time-averaging of ∼ 40 yr, two sites had death assemblages with older median ages and time-averaging > 1900 yr. A decline in the abundance of Fulvia in the post-colonial period is likely responsible for the rarity of very young shells in the surface death assemblages, while local factors such as dredging and other human activities are likely responsible for the total age-estimate variability in the two highly time-averaged surface collections. These analyses provide a geochronological context for assessing ecological changes in the harbor's benthic communities since colonization and offer an important perspective on the formation of Holocene fossil deposits
The new AMS Centre for Accelerator Science at ANSTO – a vision to the future
No full textIn 2009, the Australian Federal Government approved funding for the construction of a state-of-the-art AMS and
IBA centre for applied accelerator science at ANSTO. The final design includes a 1 MV dedicated AMS system (14C,
26Al, 10Be, 129I, Pu, U), a 6MV shared IBA and AMS system (10Be, 26Al, 36Cl, 129I), a gas-filled-magnet beam line,
and a dedicated AMS sample preparation building. The NEC accelerators are housed in a new 1500 m2 building
interconnected with the existing ANTARES AMS Facility. The 1200 m2 chemistry building was designed as a multipurpose
laboratory which provides dedicated and separated lab space for sample preparation for cosmogenic 10Be,
26Al and 36Cl, meteoric 10Be, low-level actinides (Pu,U) and an ice-core freezer storage facility for 14CH4 and 10Be
work. An independent Uranium series laboratory (for carbonates, water, quartz) is available with allocated labs for an
ICP-MC and IRMS units. The 1MV AMS accelerator was delivered in October 2013. Large beam-optical acceptance
and high-mass resolution analysers, coupled to a novel fast coupled HE and LE isotope switching system, enables
high quality radiocarbon and actinide analyses. The 6MV AMS System has 3 ion-sources (alphatross, duoplasmatron,
MC-SNICS), a high-mass resolution injector, and 3 AMS beam lines. Construction of all facilities has been completed,
and delivery of the NEC 6MV accelerator is scheduled for mid-2014. The 1 MV AMS is operational and first results
are presented in a companion conference paper. The gas-filled magnet beam line has been assembled and tested with
stable beams. The AMS sample chemistry building is operational and commissioned. The cosmogenic lab covers an
area of 250 m2, and allows parallel sample processing
Neutron Diffraction Measurements of Residual Stress and Mechanical Testing of Pressure Sintered Metal-Ceramic Composite Systems.
No full textAbstract. Functionally graded materials (FGMs) are composite materials which vary in phase composition, microstructure and properties over one or more dimensions. They are a good potential choice for nuclear reactor components as they can be engineered to effectively resist corrosion and radiation damage. In the case of a metal-ceramic FGM, they can mate the strength and ductility of a metal with the hardness and toughness of a ceramic. A series of composite samples of variable metal-ceramic ratios was manufactured by hot uniaxial pressing in cylinders. Bulk uniform samples of a certain composition were manufactured as a more efficient way of studying FGMs without the extreme gradient required in practical applications. Thermally and mechanically generated stresses, inherent in composites, frequently create conditions for micro-cracking development, depending on the material’s micro-structural characteristics and the thermo-mechanical processing route. Bulk stress measurements in the prepared samples were carried out on the Kowari diffractometer on the OPAL reactor at ANSTO. Both phases – metal matrix and ceramic inclusions – were measured in both axial and lateral directions for full characterisation of the composite stress state. When compared against analytical evaluation, experimental results, for some samples, demonstrated significant stress relaxation with micro-cracking being the main suspect. Copyright © 2016 by the author(s
Response of thin-skinned sandwich panels to contact loading with flat-ended cylindrical punches: Experiments, numerical simulations and neutron diffraction measurements.
No full textThe response of aluminium foam-cored sandwich panels to localised contact loading was investigated experimentally and numerically using flat-ended cylindrical punch of four varying sizes. ALPORAS and ALULIGHT closed-cell foams of 15 mm thickness with 0.3 mm thick aluminium face sheets (of 236 MPa yield strength) were used to manufacture the sandwich panels. Face sheet fracturing at the perimeter of the indenter, in addition to foam cells collapse beneath the indenter and tearing of the cell walls at the perimeter of the indenter were the major failure mechanisms of the sandwich panels, irrespective of the strength and density of the underlying foam core. The authors employed a 3D model in ABAQUS/Explicit to evaluate the indentation event, the skin failure of the face sheets and carry out a sensitivity study of the panel's response. Using the foam model of Deshpande and Fleck combined with the forming limit diagram (FLD) of the aluminium face sheet, good quantitative and qualitative correlations between experiments and simulations were achieved. The higher plastic compliance of the ALPORAS led to increased bending of the sheet metal and delayed the onset of sheet necking and failure. ALULIGHT-cored panels exhibited higher load bearing and energy absorption capacity, compared with ALPORAS cores, due to their higher foam and cell densities and higher yield strength of the cell walls. Additionally, they exhibited greater propensity for strain hardening as evidenced by mechanical testing and the neutron diffraction measurements, which demonstrated the development of macroscopically measurable stresses at higher strains. At these conditions the ALULIGHT response upon compaction becomes akin to the response of bulk material with measurable elastic modulus and evident Poisson effect. Copyright © 2017 Elsevier B.V
Lower Hunter particle characterisation study 1st progress report
Get PDFThe Lower Hunter Particle Characterisation Study was commissioned by the NSW Environment Protection Authority in 2013 to investigate the composition and major sources of particle pollution in the Lower Hunter. The study was conducted by scientists from the former Office of Environment and Heritage (OEH), CSIRO and the Australian Nuclear Science and Technology Organisation (ANSTO), with oversight from the NSW Ministry of Health, and completed in 2016. Focusing on very small particles, invisible to the human eye, which can be inhaled and can pass through the throat and nose and into the lungs, the study aimed to determine the composition and major sources of fine particles (PM2.5) and coarse particles (PM2.5-10). Fine particles were monitored at four sites, including two sites representative of regional population exposures (Newcastle, Beresfield) and two sites near the Port of Newcastle (Mayfield and Stockton). Coarse particles were monitored at Mayfield and Stockton, the two sites near the Port of Newcastle
When is a Tsunami a Mega-Tsunami?
No full textThe 2004 Indian Ocean Tsunami is commonly called a mega-tsunami, and this attribute has also been linked to the 2011 Tohoku-oki tsunami. However, since this term was first coined in the early 1990's there have been very few attempts to define it. As such it has been applied in a rather arbitrary fashion to a number of tsunami characteristics, such as wave height or amplitude at both the source and at distant locations, run-up height, geographical extent and impact. The first use of the term is related to a tsunami generated by a large bolide impact and indeed it seems entirely appropriate that the term should be used for such rare events on geological timescales. However, probably as a result of media-driven hyperbole, scientists have used this term at least twice in the last decade, which is hardly a significant portion of the geological timescale. It therefore seems reasonable to suggest that these recent unexpectedly large events do not fall in the category of mega-tsunami but into a category of exceptional events within historical experience and local perspective. The use of the term mega-tsunami over the past 14 years is discussed and a definition is provided that marks the relative uniqueness of these events and a new term, appropriately Japanese in origin, namely that of souteigai-tsunami, is proposed. Examples of these tsunamis will be provided
Photocatalytic Properties of TiO2: Evidence of the key role of surface active sites in water oxidation.
No full textPhotocatalytic activity of oxide semiconductors is commonly considered in terms of the effect of the band gap on the light-induced performance. The present work considers a combined effect of several key performance-related properties (KPPs) on photocatalytic activity of TiO2 (rutile), including the chemical potential of electrons (Fermi level), the concentration of surface active sites, and charge transport, in addition to the band gap. The KPPs have been modified using defect engineering. This approach led to imposition of different defect disorders and the associated KPPs, which are defect-related. This work shows, for the first time, a competitive influence of different KPPs on photocatalytic activity that was tested using oxidation of methylene blue (MB). It is shown that the increase of oxygen activity in the TiO2 lattice from 10–12 Pa to 105 Pa results in (i) increase in the band gap from 2.42 to 2.91 eV (direct transitions) or 2.88 to 3 eV (indirect transitions), (ii) increase in the population of surface active sites, (iii) decrease of the Fermi level, and (iv) decrease of the charge transport. It is shown that the observed changes in the photocatalytic activity are determined by two dominant KPPs: the concentration of active surface sites and the Fermi level, while the band gap and charge transport have a minor effect on the photocatalytic performance. The effect of the defect-related properties on photoreactivity of TiO2 with water is considered in terms of a theoretical model offering molecular-level insight into the process. Copyright © 2017 American Chemical Societ
Optimal target region for subject classification on the basis of amyloid PET images
No full textClassification of subjects on the basis of amyloid PET scans is increasingly being used in research studies and clinical practice. Although qualitative, visual assessment is currently the gold standard approach, automated classification techniques are inherently more reproducible and efficient. The objective of this work was to develop a statistical approach for the automated classification of subjects with different levels of cognitive impairment into a group with low amyloid levels (AβL) and a group with high amyloid levels (AβH) through the use of amyloid PET data from the Alzheimer Disease Neuroimaging Initiative study. Methods: In our framework, an iterative, voxelwise, regularized discriminant analysis is combined with a receiver operating characteristic approach that optimizes the selection of a region of interest (ROI) and a cutoff value for the automated classification of subjects into the AβL and AβH groups. The robustness, spatial stability, and generalization of the resulting target ROIs were evaluated by use of the standardized uptake value ratio for 18F-florbetapir PET images from subjects who served as healthy controls, subjects who had mild cognitive impairment, and subjects who had Alzheimer disease and were participating in the Alzheimer Disease Neuroimaging Initiative study. Results: We determined that several iterations of the discriminant analysis improved the classification of subjects into the AβL and AβH groups. We found that an ROI consisting of the posterior cingulate cortex/precuneus and the medial frontal cortex yielded optimal group separation and showed good stability across different reference regions and cognitive cohorts. A key step in this process was the automated determination of the cutoff value for group separation, which was dependent on the reference region used for the standardized uptake value ratio calculation and which was shown to have a relatively narrow range across subject groups. Conclusion: We developed a data-driven approach for the determination of an optimal target ROI and an associated cutoff value for the separation of subjects into the AβL and AβH groups. Future work should include the application of this process to other datasets to facilitate the determination of the translatability of the optimal ROI obtained in this study to other populations. Ideally, the accuracy of our target ROI and cutoff value could be further validated with PET-autopsy data from large-scale studies. It is anticipated that this approach will be extremely useful for the enrichment of study populations in clinical trials involving putative disease-modifying therapeutic agents for Alzheimer disease. © 2015, by the Society of Nuclear Medicine and Molecular Imaging, Inc
Evolution of chemical and isotopic composition of inorganic carbon in a complex semi-arid zone environment: consequences for groundwater dating using radiocarbon.
No full textEstimating groundwater age is important for any groundwater resource assessment and radiocarbon (14C) dating of dissolved inorganic carbon (DIC) can provide this information. In semi-arid zone (i.e. water-limited environments), there are a multitude of reasons why 14C dating of groundwater and traditional correction models may not be directly transferable. Some include; (1) the complex hydrological responses of these systems that lead to a mixture of different ages in the aquifer(s), (2) the varied sources, origins and ages of organic matter in the unsaturated zone and (3) high evaporation rates. These all influence the evolution of DIC and are not easily accounted for in traditional correction models. In this study, we determined carbon isotope data for; DIC in water, carbonate minerals in the sediments, sediment organic matter, soil gas CO2 from the unsaturated zone, and vegetation samples. The samples were collected after an extended drought, and again after a flood event, to capture the evolution of DIC after varying hydrological regimes. A graphical method (Han et al., 2012) was applied for interpretation of the carbon geochemical and isotopic data. Simple forward mass-balance modelling was carried out on key geochemical processes involving carbon and agreed well with observed data. High values of DIC and δ13CDIC, and low 14CDIC could not be explained by a simple carbonate mineral–CO2 gas dissolution process. Instead it is suggested that during extended drought, water–sediment interaction leads to ion exchange processes within the top ∼10–20 m of the aquifer which promotes greater calcite dissolution in saline groundwater. This process was found to contribute more than half of the DIC, which is from a mostly ‘dead’ carbon source. DIC is also influenced by carbon exchange between DIC in water and carbonate minerals found in the top 2 m of the unsaturated zone. This process occurs because of repeated dissolution/precipitation of carbonate that is dependent on the water salinity driven by drought and periodic flooding conditions. This study shows that although 14C cannot be directly applied as a dating tool in some circumstances, carbon geochemical/isotopic data can be useful in hydrological investigations related to identifying groundwater sources, mixing relations, recharge processes, geochemical evolution, and interaction with surface water.© 2016, Elsevier Ltd
Epigenetic silencing of the human 18 kDa translocator protein in a T cell leukemia cell line
No full textThe mitochondrial membrane 18 kDa translocator protein (TSPO), previously known as the peripheral benzodiazepine receptor, is constitutively expressed in most organs, most abundantly in hormonal tissue and cells of mononuclear phagocyte lineage, while in the brain, TSPO expression is induced in the wake of injury, inflammation, and neurodegeneration. Increased TSPO expression is also prominent in several cancerous tissues where it appears to correlate with the degree of malignancy. Currently, TSPO is thus actively investigated as a generic biomarker for disease activity and a therapeutic target for a wide range of diseases. In this study, we report a Jurkat human T cell leukemia cell line that has only trace expression of TSPO mRNA. Through the use of bisulphite genomic sequencing, we show that the Jurkat TSPO promoter is highly methylated except for CpG sites that are adjacent to the transcription start site. Control measurements in HEK-293, HeLa, and U87-MG cells with high TSPO mRNA expression showed low levels of TSPO promoter methylation. Demethylation with 5-aza-2'-deoxycytidine (5-aza-dC) caused a dose-dependent increase in TSPO mRNA with a corresponding demethylation of the TSPO promoter in Jurkat cells. Treating HeLa and U87-MG cells with 5-aza-dC caused no change in the level of TSPO mRNA. These observations confirm the epigenetic regulation of TSPO and suggest it to be a more common mechanism by which the differential expression of TSPO in various cell types and in health and disease may be explained. ©2017 Mary Ann Liebert, Inc