17837 research outputs found
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Applying ADDIE model to develop multimedia lessons for adolescent reproductive health education in Uganda
Get PDFImplementing precision methods in personalizing psychological therapies:Barriers and possible ways forward
Get PDFDetector Development for Particle Physics and Applications to Environmental Monitoring
Get PDFThis thesis reports on the development of a novel device, called PlomBOX, employing a CMOSsensor and lead-sensing bacteria to assay lead in drinking water, up to the World Health Organisation (WHO)’s upper limit of 10 ppb. As a first step, a scientific CMOS was used to demonstrate the capability of detecting gamma energies in an Si detector from a lead-210 (210Pb) sample through calorimetry methods. While this technique is promising for dosimetry applications, it is not able to reach the WHO level in sensitivity. A second step was to explore how the sensitivity range of any device could be improved by increasing the concentration of the substance of interest in a sample. Lead doped water samples were boiled to explore if an increase in heavy metal concentration was observed. This technique was able to retain 99 ± 9% of 210Pb, allowing for an increase of its concentration. The third step involved the development of the PlomBOX. The project followed three development paths: a) Certain bacteria can change colour when in the presence of lead. A genetically modified strain of Escherichia coli sensitive to lead concentrations up to 10 ppb was developed together with a team of biologists. This constitutes the biosensor that emits colour in proportion to the presence of lead. b) Bacteria response is imaged using a microprocessor (ESP32) with a camera module. This constitutes the optical metrology component of the PlomBOX. c) Data acquisition and control of the PlomBOX is achieved through a Bluetooth connection with thePlomApp, a custom-developed mobile phone application. Data are sent from the PlomApp to a database where a bespoke automated analysis software provides a result of the lead concentration in a sample of water. A full description of the experimental set up and analysis software is provided and results of the first in situ assay are discussed
Sustainable aquatic resource management and inland fisheries in tropical Asia:Interdisciplinary and transdisciplinary approaches
Get PDFThe intensive utilization of tropical inland water bodies for multiple and sometimes competing activities underlines the necessity for their integrated and holistic co-management. This paper presents our synthesis on lake and reservoir fisheries in South and Southeast Asia as social–ecological systems, based on a synopsis of our research findings from a previous EU- funded research programme in Sri Lanka, Thailand and the Philippines (FISHSTRAT project). The paper attempts to merge our results with recent developments in research, policy and practice. We explore the effects of the main external and internal control mechanisms of the trophic state and pinpoint to the high production potential of traditionally unexploited small indigenous fish species. The limitations of conventional centralized management systems highlight the importance of introducing transdisciplinary approaches which integrate limnology, fish ecology and fisheries with the interests of other resource using stakeholders and decision makers in order to develop locally appropriate co-management strategies for sustainable aquatic resource use
Dementia Education Opportunities for Pre-Registration Occupational Therapy and Physiotherapy Students- A Scoping Review
Get PDFDesign-led solutions for reducing airline food waste:A participatory approach to develop behaviour change interventions
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HPTPC - A High-Pressure Time Projection Chamber for Neutrino Physics
Get PDFThe precise characterisation of neutrino-nuclei interactions is vital for future long baseline neutrino experiments to meet their sensitivity goals. A time projection chamber (TPC) filled with a high-pressure gas is an ideal detector for making these measurements. Such a detector could achieve a lower energy threshold than a liquid or solid detector, while also allowing more neutrino events to be recorded than would be in a gas TPC operated at atmospheric pressure. High-pressure gas TPCs are also promising detectors for characterising neutrino beams in long baseline neutrino experiments. For this reason, the 2021 Deep Underground Neutrino Experiment (DUNE) near detector (ND) conceptual design report (CDR) includes a design for a high-pressure gas TPC as part of the DUNE ND complex. This thesis covers two high-pressure TPC set-ups which were operated at Royal Holloway, University of London between 2018 and 2022. The first half of the thesis covers the commissioning of a transparent TPC with hybrid optical and charge gain readout, based on the DMTPC (Dark Matter Time Projection Chamber) experiment. The second half investigates the suitability of multiwire proportional chambers (MWPCs) taken from the ALICE TPC for use as the readout chambers of a high-pressure gas TPC in the DUNEND. It reports the successful operation of an ALICE TPC outer readout chamber (OROC) at pressures so far up to 4 bar absolute with Ar-CH4 and Ar-CO2 gas mixtures. From these results, a study into the expected ability of the high-pressure TPC design from the DUNE ND CDR concludes that, given some further study, the TPC may be capable of reconstructing and separating final states by pion multiplicity with an efficiency of at least 70 %. This is a significant improvement to the reconstruction capabilities of the ND; without a high-pressure TPC, final states containing multiple pions would be expected to be correctly reconstructed only 50 % of the ti
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