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Química Farmacéutica I. Tema 8. Farmacología de procesos infecciosos
No full textTemas de la Asignatura Química Farmacéutica I de 3º de Farmacia
On “innovation and institutional ownership”
No full textIn their article “Innovation and Institutional Ownership”, Aghion, Van Reenen and Zingales (2013) find that the rise in institutional stock ownership in the U.S. during the 1990s led to an increase in corporate innovation, as measured by patent and patent citation counts. Their article concludes that “contrary to the view that institutional ownership induces a short-term focus in managers, we find that their presence boosts innovation” (p. 302). Subsequent research has generally accepted this finding at face value. However, we uncover several critical issues with their data. Addressing these issues renders the results economically and statistically insignificant and, in some instances, even suggests a negative relationship between institutional ownership and U.S. innovation
Building energy performance metamodels for district energy management optimisation platforms
No full textReactive control strategies lack the flexibility necessary to optimize the operational costs of buildings and district systems. To overcome this limitation and to enable the transition to model predictive control strategies (MPC), the development of dedicated control platforms and models is required. Predictive models for district systems management should provide supply and demand side integrated modelling, high accuracy, generalization capacity and reduced computational times. However, traditionally available MPC solutions do not meet these requirements as simplified models offer short computational times but lack the required accuracy; detailed physics-based models provide satisfactory generalization but at the expense of high computational costs; and the generalization capacity of data models is constrained by the quality and availability of data. In contrast, metamodels developed through the combined use of physics-based models and machine learning techniques offer a powerful alternative at reduced computational cost. This paper describes an upgraded Integrated District Model concept developed through co-simulation coupling metamodels of buildings with a district heating infrastructure Modelica model. Furthermore, the process to produce the metamodels and optimization engine required to generate demand flexibility optimization functionalities for the buildings of the Stepa Stepanovic subnetwork (Belgrade) is depicted. Starting from the development of metamodels of instances of specific buildings (residential and educational use) the process was expanded to provide additional generalization to define, (1) a generic metamodel with the capacity to reproduce the behaviour of any instance of building of the residential typology, and (2) metamodels with generalization capacity in relation to operational settings. As part of this process the potential of several machine learning algorithms (e.g Support Vector Machines, etc) was evaluated including the latest ensemble boosting methods (e.g. Adaboost, Gradient Boosting and Extreme Gradient Boosting) with comparatively low use in the building simulation community. Finally, a virtual test bed consisting in metamodels coupled to an optimization engine based on genetic algorithms, was implemented, and compared to a traditional Physics-based model MPC solution (EnergyPlus-GENOPT), to evaluate the potential of the developed building level optimization functionalities. The metamodels and optimization engine were able to reproduce the optimized settings identified by the EnergyPlus-GENOPT MPC solution with cost savings potentials of 5-10%
Valorization of cheese whey: closing the loop from protein extraction to whey protein film composting.
No full textWhey protein extracted from cheese-making by-products was analysed as a potential alternative for both food waste valorisation and food packaging waste reduction. Whey protein was ultrafiltered from local cheese whey and used for film manufacture via compression moulding. The physicochemical characterization of the extracted protein showed that the purity of the extracted protein was 91.6% wt. FTIR and XRD analyses, as well as SEM images, revealed the presence of lactose in the extracted protein. The solubility of the films made in water indicated that whey protein films would be suitable for packaging fatty foods, e.g. cheese, thus following the circular economy strategy. Furthermore, since the biodegradability of the f ilms was higher than 70% after 48 h under composting conditions, it can be concluded that whey protein f ilms are rapidly compostable in any industrial composting facility, highlighting the more sustainable character of these films. Finally, the environmental assessment confirmed that the film manufacturing process was the stage contributing the most to the environmental impact and, thus, this step should be optimised to reduce the environmental footprint of the films developed
Linking institutional context to the community and career embeddedness of skilled migrants: The role of destination- and origin-country identifications
No full textMigration is one of the most pressing global issues of our time. However, relatively little is known about the factors and mechanisms that govern the post-migration experiences of skilled migrants. We adopt an acculturation- and social identity-based approach to examine how differences between institutional characteristics in the destination and origin country, as well as migrants’ experiences with formal and informal institutions shape their identification with the destination and origin country and contribute to their community and career embeddedness. Our study of 1709 highly skilled migrants from 48 origin countries in 12 destination countries reveals that the institutional environment migrants encounter provides both sources of opportunity (potential for human development and value-congruent societal practices) and sources of disadvantage (experienced ethnocentrism and downgrading). These contrasting dynamics affect migrants’ destination-country identification, their origin-country identification and, ultimately, their embeddedness in the destination country. Our results have important implications for multinational enterprises and policy makers that can contribute to enhancing skilled migrants’ community and career embeddedness. For example, these actors may nurture a work environment and provide supportive policies that buffer against the institutional sources of disadvantage we identified in this study, while helping migrants to leverage the opportunities available in the destination country
Reflexiones a propósito de una nueva inscripción romana en territorio vascón (Santa Criz de Eslava, Navarra)
No full textLa presente nota aporta la editio prínceps de un nuevo titulus sepulchralis que viene a incrementar el ya extenso repertorio epigráfico de la ciudad vascónica, y romana, de Santa Criz de Eslava (Eslava, Navarra). Al hilo del lugar de su procedencia y de otros materiales con ella localizados se introducen algunas reflexiones sobre la economía de las ciudades vasconas en época alto-imperial romana que abundan en nuestro conocimiento de las fuentes de riqueza de la elite local de la zona
Pensamiento y filosofía en las obras de Fiódor Dostoyevski: “Crimen y castigo” y “Los hermanos Karamazov”
No full textLa obra de Fiódor Dostoyevski ha sido ampliamente estudiada a lo largo de los tiempos. El
escritor ruso ha influido en multitud de autores posteriores a él. En este TFG, estableceré
las conexiones y semejanzas entre Dostoyevski y las corrientes nihilistas y existencialistas.
En particular, los autores en los que se centra este trabajo son Albert Camus, Jean-Paul
Sarte y Friedrich Nietzsche. En primer lugar, estudiaré el contexto histórico en el
que vive Fiódor. También destacaré la personalidad de cada personaje principal de su obra,
proponiéndolo como propulsor de las corrientes filosóficas estudiadas. Por último, después
de estudiar a Sarte, Camus y Nietzsche, acabaré el TFG con una serie de conclusiones que
incitan a pensar en que Dostoyevski fue el padre "literario" y "filósofico" de estos escritores
Química Farmacéutica I. Antibióticos. Parte 1, reacción 1: Síntesis del derivado enamina. Seguimiento mediante CCF
No full textTemas de la Asignatura Química Farmacéutica I de 3º de Farmacia
Fichas de buenas prácticas para la atención a problemas de salud mental en Educación Primaria. Una herramienta de ayuda para los centros educativos. Ficha individual: Ansiedad
No full textMaterial elaborado en el marco del proyecto de investigación orientado a la transferencia del conocimiento,
"Revisión y valoración de políticas de prevención e intervención en salud mental infanto-juvenil
en centros educativos” (IP, Martiño Rodríguez-González, ICS-UNAV) desarrollado por la Universidad
de Navarra en colaboración con la Universidad Internacional de La Rioja UNIR- ITEI. Esta guía pretende proporcionar al profesorado un marco de comprensión sencillo acerca de los problemas de salud mental en la etapa de primaria, así como identificar señales de alarma y ofrecer pautas para un primer abordaje con los estudiantes que puedan estar experimentando tales problemas. La guía busca promover y prevenir la salud mental, pero en ningún diagnosticar u orientar sobre la forma de intervenir. El objetivo de este documento es prevenir y detectar los problemas de salud mental, además de planificar el acompañamiento, cuidado y, en caso necesario, derivación a los servicios especializados de salud mental. Ayudar al alumno es, en gran medida, conseguir coordinarse y colaborar con las familias y otros profesionales externos al centro educativo. Para cada una de las fichas incluidas en este documento, se sigue la misma estructura: primero, una introducción sobre el problema de salud mental o el trastorno en cuestión; segundo, se detallan las principales señales de alarma que pueden ser observadas por el docente en diferentes espacios y situaciones escolares; finalmente, se proporcionan sugerencias sobre su abordaje, ¿qué puede hacer el maestro o profesor ante esto
