University of Navarra

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    Cassandra and A Room of One's Own: A common cry of frustration

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    In this manuscript, we explore the connections between Florence Nightingale's Cassandra and Virginia Woolf's A Room of One's Own while taking the authors' personal and social contexts into account. We conduct a detailed textual analysis from a feminist perspective. Cassandra and A Room of One's Own exhibit singular textual commonalities, such as evidence of trauma, the integration of myth and fiction as literary devices aimed at facilitating the author's access to various social spheres, the use of interpellations to impact the audience, and an argument for education as a path by which privileged women can enter the public realm. Both authors' personal wounds and intellectual frustrations influenced their work, thus making their writing very powerfu

    The role of experience and diversity on research consortia’ performance: an exploratory approach

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    In the realm of academic engagement, this study directs its focus toward a policy instrument that has received surprisingly scant attention within the literature, despite its substantial investment: European Union-funded research projects. These projects are designed to foster collaboration and establish a framework that supports and fortifies the creation and dissemination of exceptional knowledge and cutting-edge technologies. These endeavors are anticipated to fuel economic growth, spur social development, and address global challenges. Within this study, we delve into the impact of team experience and diversity on the research performance of consortia — groups of organizations — that have been successfully awarded funding within the FP7 and H2020 funding schemes. In order to dissect the influence of learning, our analysis is confined to consortia that have collaborated on multiple occasions. Drawing from data sourced from Community Research and Development Information Service, our findings unveil that beyond the monetary allocation, an array of team attributes and environmental factors play a role in augmenting team performance

    Changes in urinary metabolomic profile show the effectiveness of a nutritional intervention in children 6–12 years old: The ALINFA study

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    Diet plays an essential role in health and disease. Therefore, its determination is an important component of many investigations. The aim of the study was to evaluate the effect of a nutritional intervention on the urinary metabolome in children aged 6–12 years. Also, it was intended to identify biomarkers of diet quality and dietary intake. A 2-month, randomized, controlled, parallel trial was conducted in Spanish children. The analyses focused on the ALINFA group, which followed a full-fixed meal plan including healthy products, ready-to-eat meals, and healthy recipes. Diet quality was assessed by the KIDMED index and dietary intake by a food frequency questionnaire. Untargeted metabolomic analysis on urine samples was carried out, and multivariate analyses were performed for pattern recognition and characteristic metabolite identification. PLS-DA and Volcano plot analyses were performed to identify the discriminating metabolites of this group. 12 putative metabolites were found to be the most relevant to this intervention. Most of them were products derived from protein and amino acid metabolism (N-Ribosylhistidine, indolacrylic acid, and peptides) and lipid metabolism (3-oxo-2-pentylcyclopentane-1-hexanoic acid methyl, SuberoylL-carnitine, and 7-Dehydrodichapetalin E). All these metabolites decreased after the intervention, which was mainly associated with a decrease in the consumption of fatty meat and total fat, especially saturated fat. In turn, N-Ribosylhistidine and SuberoylL-carnitine were negatively associated with diet quality, as well as able to predict the change in KIDMED index. In conclusion, the changes observed in urinary metabolome demonstrate the effectiveness of the ALINFA nutritional intervention

    Hydrolysis of riboflavins in root exudates under iron deficiency and alkaline stress

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    Riboflavins are secreted under iron deficiency as a part of the iron acquisition Strategy I, mainly when the external pH is acidic. In plants growing under Fe-deficiency and alkaline conditions, riboflavins have been reported to accumulate inside the roots, with very low or negligible secretion. However, the fact that riboflavins may undergo hydrolysis under alkaline conditions has been so far disregarded. In this paper, we report the presence of riboflavin derivatives and products of their alkaline hydrolysis (lumichrome, lumiflavin and carboxymethylflavin) in nutrient solutions of Cucumis sativus plants grown under different iron regimes (soluble Fe-EDDHA in the nutrient solution, total absence of iron in the nutrient solution, or two different doses of FeSO4 supplied as a foliar spray), either cultivated in slightly acidic (pH 6) or alkaline (pH 8.8, 10 mM bicarbonate) nutrient solutions. The results show that root synthesis and exudation of riboflavins is controlled by shoot iron status, and that exuded riboflavins undergo hydrolysis, especially at alkaline pH, with lumichrome being the main product of hydrolysis

    Parentalidad, diferenciación del self y agresión entre iguales en adolescentes de países hispanohablantes.

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    Introducción: La agresión entre iguales durante la adolescencia es un problema que cada vez preocupa más. Para prevenirla, es importante conocer los factores que influyen sobre ella. El objetivo de este trabajo fue evaluar la asociación que la parentalidad positiva y la diferenciación del self tienen con la agresión entre pares durante la adolescencia, en países hispanohablantes. Específicamente, se quería averiguar si la diferenciación del self tiene un papel moderador y/o mediador en la asociación entre parentalidad positiva y agresión entre pares. Métodos: Se pasó un cuestionario online a 7170 adolescentes (12-17 años) de Argentina, Chile, Ecuador, España, México y Perú. El cuestionario evaluaba la parentalidad, la diferenciación y la presencia de agresión sufrida o ejercida. A través de regresiones logísticas univariantes y multivariantes, y de modelos de ecuaciones estructurales (SEM), se evaluó la asociación entre estas variables. Resultados: El afecto parental y las dimensiones de la diferenciación del self (reactividad emocional y la distancia emocional) se asociaron con menor frecuencia de agresión sufrida y ejercida, tanto entre chicos como entre chicas. No se apreció papel de la exigencia parental. No se apreció papel moderador de reactividad o distancia emocional en la asociación entre afecto parental y agresión sufrida o ejercida. En la asociación entre afecto parental y agresión sufrida o ejercida se encontró un efecto directo y un efecto indirecto, mediado por la reactividad emocional y por la distancia emocional. Conclusiones: Los resultados sugieren que el afecto parental se asocia con una menor frecuencia de agresión, y que la diferenciación del self media parcialmente dicha asociación

    Interactions between struvite and humic acid and consequences on fertilizer efficiency in a nonacidic soil

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    The effect of humic acid extracted from peat (AHt) on improving the struvite (STR) fertilizing efficiency is explored. To this end, a soil incubation study is correlated to plant assays comparing STR, STR-AHt, and superphosphate (SSP). Characterization techniques confirm the incorporation of the AHt into the STR. The P-pool distribution of STR and SSP is similar in the soil incubation, with STR-AHt presenting a higher labile P at 90 days passing from 10 to 15% P from SSP and STR to 25% P with STR-AHt. However, when applied to barley and tomato, STR yields more shoot P content, aboveground biomass, and residual P in soil than SSP. STR-AHt does not improve the STR results. The poor correlation observed between soil incubation and plant trials highlights the role of the rhizosphere in testing the fertilizer efficiency of STR. Mechanistic assays indicate the key role of rhizosphere pH. Finally, molecular modeling reveals a higher stabilization of STR with AHt, which could reduce P release decreasing the fertilizing potential of STR-AHt, as observed in the pot trials

    Memoria de actividades 2021

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    En el trasfondo de un año que continuó desafiándonos con las secuelas de la pandemia global, la Biblioteca mantuvo su compromiso de servicio, adaptación y transformación. El 2021 fue un capítulo en nuestra historia que marcó la continuidad de medidas cautelares en respuesta al Covid- 19, pero también se convirtió en el testimonio de un avance significativo en diversos aspectos que han fortalecido nuestra presencia y servicio en la comunidad universitaria. Las secuelas del Covid-19 no solo persistieron sino que moldearon aún nuestras acciones. La prioridad fue mantener un ambiente seguro para usuarios y personal. Continuamos implementando estrictos protocolos de higiene y seguridad, adaptándonos a las fluctuaciones de normativas y restricciones para garantizar el acceso continuo a recursos y servicios esenciales, aún en tiempos desafiantes. Un punto destacado en el transcurso del año fue la firma de acuerdos transformativos con editoriales clave, una gesta que fortaleció nuestra capacidad para ofrecer recursos académicos y científicos de vanguardia a nuestra comunidad. Estos acuerdos no solo ampliaron nuestro acervo, sino que sentaron las bases para una colaboración más estrecha y sostenible en el ámbito editorial, enfocada en la democratización del conocimiento. Asimismo, es en este año en el que se ha materializado la integración de la Biblioteca de Tecnun en San Sebastián dentro del Servicio de Bibliotecas de la Universidad de Navarra. Esta integración no solo consolidó nuestra presencia a nivel regional, sino que también enriqueció nuestra oferta y acceso a recursos especializados, fomentando la sinergia entre ambos campus y potenciando la colaboración interdisciplinaria. El dinamismo de nuestro equipo humano también ha sido un aspecto relevante. A lo largo del año, experimentamos cambios significativos con bajas y nuevas incorporaciones de personal. Estos movimientos no solo representan una evolución natural en la vida institucional, sino que también subrayan el compromiso continuo de la Biblioteca con la excelencia, la diversidad de perspectivas y el constante crecimiento profesional. El año 2021 se ha caracterizado por la capacidad de la Biblioteca de adaptación, la búsqueda de nuevas formas de trabajo y el firme compromiso con nuestra comunidad universitaria. En este informe anual, se detallan los retos superados, los logros alcanzados y cada paso dado hacia el desarrollo continuo

    Development and validation of a realistic type III esophageal atresia simulator for the training of pediatric surgeons

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    Background The technical complexity and limited casuistry of neonatal surgical pathology limit the possibilities of developing the necessary technical competencies by specialists in training. Esophageal atresia constitutes the paradigm of this problem. The use of synthetic 3D models for training is a promising line of research, although the literature is limited. Methods We conceptualized, designed, and produced an anatomically realistic model for the open correction of type III oesophageal atresia. We validated it with two groups of participants (experts and non-experts) through face, construct, and content-validity questionnaires. Results The model was validated by nine experts and nine non-experts. The mean procedure time for the experts and non-experts groups was 34.0 and 38.4 min, respectively. Two non-experts did not complete the procedure at the designed time (45 min). Regarding the face validity questionnaire, the mean rating of the model was 3.2 out of 4. Regarding the construct validity, we found statistically signifcant diferences between groups for the equidistance between sutures, 100% correct in the expert group vs. 42.9% correct in the non-expert group (p=0.02), and for the item “Confrms that tracheoesophageal fstula closure is watertight before continuing the procedure”, correctly assessed by 66.7% of the experts vs. by 11.1% of non-experts (p=0.05). Concerning content validity, the mean score was 3.3 out of 4 for the experts and 3.4 out of 4 for the non-experts. Conclusions The present model is a cost-efective, simple-to-produce, and validated option for training open correction of type III esophageal atresia. However, future studies with larger sample sizes and blinded validators are needed before drawing defnitive conclusions

    Evaluation of a Novel Automated Allergy Intradermal Skin Test Reader: A Diagnostic Accuracy Study

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    Automated Nexkin and manual intradermal wheal size and area measurement were evaluated in a company-sponsored study. Nexkin sensitivity and specificity were 99% and 97% but need confirmation in a second cohort

    Las recreaciones de Don Quijote de George Almar y George MacFarren

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