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The dawning of the age of the litigation entrepreneur
No full textIn the United States, claims aggregators have appeared as a new form of litigation entrepreneur. Claims aggregators collect claims from nominal claim holders then prosecute the claims in a single action. As such they constitute a potential form of competition for class action attorneys and litigation financiers as providers of access to justice. This article examines claims aggregation in three common law jurisdictions--England, Australia and the United States--and compares claims aggregation with another well established form of entrepreneurial litigation, the class action. Legal and financial impediments to the growth in claims aggregation are also considered.
Inhibition of atherosclerotic lesion development in the ApoE-/- mouse by a novel ß-oxa polyunsaturated fatty acid
No full textRecent findings that a novel polyunsaturated fatty acid, β-oxa 23:4n-6, inhibits adhesion molecule expression on vascular endothelial cells and leukocyte adhesion led us to examine its ability to inhibit the development of atherosclerosis in the apoE-deficient (apoE-/-) mouse. The mice were kept on normal chow or a high-fat/high-cholesterol diet for various periods and treated with either vehicle or β-oxa 23:4n-6 by the intraperitoneal route. The hearts and aortae were isolated and lesion development at the aortic root was determined. Morphometric assessment revealed that lesion development was a function of compensatory aortic enlargement, suggesting that measurement of plaque size per se is the appropriate assessment of lesion size. Using this criterion, we found that atherosclerosis development was reduced in response to β-oxa 23:4n-6, plaque size by 74% and aortic cross-sectional area by 62%, under an optimized regime. The number of foam cells per unit tissue area in the lesions of β-oxa 23:4n-6-treated mice was significantly reduced by 37.5%. The blood levels of β-oxa23:4n-6 in these mice exceeded the concentrations previously found to inhibit adhesion molecule expression in cultured endothelial cells. These data show that β-oxa23:4n-6 protects against experimental atherosclerosis, most likely by reducing the number of infiltrating monocytes.
Private irrigators in southern Alberta: a survey of their adoption of improved irrigation technologies and management practices
No full textOn optimal sensor placement for time-difference-of-arrival localization utilizing uncertainty minimization
No full textA holistic client-centred program for vulnerable frequent hospital attenders: cost efficiencies and changed practices
No full textInvestigating the performance of food supply chains through IT integration: A proposed model
No full textEvolution of ECG changes in tako tsubo cardiomyopathy: arrhythmias first, QT prolongation later?
No full textA framework for the flexible instantiation of large scale software process tailoring
No full textDue to the variety of concerns affecting software development in large organizations, generic software processes have to be adapted to project specific needs to be effectively applicable in individual projects. We describe the architecture of a tool aiming to provide support for tailoring and instantiation of reference processes. The goal is to minimize the effort for the individualisation of generic software processes to project specific needs. In contrast to existing approaches, our prototype provides flexible support for adaptation decisions made by project managers while adhering to modelling constraints stated by the used modelling language, enterprise policies or business process regulations.