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Using Riveter to Map Gendered Power Dynamics in Hades/Persephone Fanfiction
No full textItem does not contain fulltext14 september 202
Temporal trends in the treatment of relapsing minimal change podocytopathy-a binational cohort study
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324694.pdf (Publisher’s version ) (Open Access)BACKGROUND AND HYPOTHESIS: While the primary treatment for minimal change disease (MCD) is prednisolone, the immunosuppressive treatment at relapse is less well defined. More treatment options for MCD have become available and concerns about the adverse effects of prednisolone have been raised. It is unclear to what extent this has influenced the treatment of relapsing disease. Thus, the objective of this study is to characterize the changes in the immunosuppressive treatment of relapse in MCD over the past 35 years. METHODS: A multicentre, retrospective cohort including adult patients with biopsy-proven MCD from 13 hospitals in Denmark and the Netherlands between 1985 and 2022. Patients were identified from pathology registers. Information on treatment and clinical outcomes was retrieved from health records. Treatment before and after 2010 was compared. RESULTS: The study included 239 patients with a median age of 46 years, 55% female and 64% being diagnosed before 2010. A first relapse was identified in 50% and a second relapse in 28%. The most frequently prescribed treatment at first relapse was prednisolone monotherapy before and after 2010 (67% and 44% of patients, respectively), while the use of calcineurin inhibitors (CNI) increased 3-fold after 2010 compared with before 2010. At second relapse CNI was the most frequently prescribed treatment after 2010, while the use of both cyclophosphamide and prednisolone decreased when compared with before 2010. A similar trend was observed at the 3rd to 14th relapse with CNI (44% of patients) and rituximab (35% of patients) being the most frequently prescribed treatments after 2010 while the use of cyclophosphamide and prednisolone decreased (0% and 21% of patients, respectively). Regardless of treatment, remission rates remained high. CONCLUSION: The treatment of relapses in MCD has changed since 2010 with reduced use of prednisolone monotherapy and cyclophosphamide, and increased use of CNI and rituximab
Extreme mass-ratio inspiral within an ultralight scalar cloud: Scalar radiation
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326001.pdf (Publisher’s version ) (Closed access)
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326001pre.pdf (Author’s version preprint ) (Open Access
Bothnian Sea US5B sediment incubations metagenome krona plots by SingleM
No full textItem does not contain fulltextSediment used for incubations is from 35 - 40 cmbsf (MC) and 134 - 137 cmbsf (GC).
Different substrates were added to the treatments: NO2- only, NH4+ and NO2-, NH4+ and O
Fully Automated Tooth Segmentation and Labeling for Both Full- and Partial-Arch Intraoral Scans Using Deep Learning
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322393.pdf (Publisher’s version ) (Open Access)13 p
First observation of quantum oscillations by transport measurements in semi-destructive pulsed magnetic fields up to 125 T
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326451.pdf (Publisher’s version ) (Closed access
Noot bij: EHRM 29 augustus 2024, AB, 2025, 241 (Onpartijdigheid griffier en artikel 6 EVRM (Tsulukidze en Rusulashvili t. Georgie))
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324026.pdf (Publisher’s version ) (Closed access)29 augustus 202
Longitudinal study on teaching reduction to second language learners
No full textItem does not contain fulltextWe tested four groups of intermediate Dutch learners of French. The participants of three experimental groups followed 10 lessons of 30 minutes each. Two experimental groups received the same explicit instruction about reduced forms after which one group only practiced the comprehension of reduced forms (the Explicit Instruction Comprehension group; hereafter EIComp), while the other group practiced the production of reduced forms (the Explicit Instruction Production group; hereafter EIProd). The third experimental group was also exposed to reduced forms but only received grammar instruction (the Grammatical Instruction group; hereafter GramI). The last group, the control group (hereafter Control), did not follow any lessons. The participants’ ability to comprehend reduced forms in context was tested at four different moments with four different cloze tests (hereafter, T0, T1, T2, T3): before, during, and after the lessons, as well as three months after the lessons had ended. At the end of the last test (T3), we verified whether the participants knew the words they had heard during all four tests (test labelled Expressions in the folders and documents). At the start of the study, we first assessed the participants with a pre-test. The pre-test consisted of a verbal working memory test in Dutch, followed by a self-paced reading task, two grammar exercises, and one audio and one audio-visual comprehension tasks in French. The word document Files description.docx presents a timeline of the unfolding of the experiment, and details the content of each folder and file.The consent forms templates, and the audio files for the cloze tests and pre-test, as well as their content are to be found under MATERIALS. RAW DATA contains the raw output files.DATA is the data we used for our statistical analyses.All data files are accompanied by a word document named 'variables' which explains the names of the variables and their type
Dietary impact on the gut resistome: western diet independently increases the prevalence of antibiotic resistance genes within the gut microbiota
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322947.pdf (Publisher’s version ) (Open Access)28 juli 202512 p
Development of an Evidence-Based and Theory-Informed Self-Management Intervention for People with Lipoedema: An Intervention Mapping Study.
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324327.pdf (Publisher’s version ) (Open Access)BACKGROUND: The etiology of lipoedema remains unclear, making diagnosis and treatment challenging. Current treatment primarily consists of general lifestyle recommendations, with effective self-management being essential for integrating these recommendations into daily life. However, no self-management interventions currently address the unique needs of people with lipoedema. This study aimed to develop an evidence-based, theory-informed intervention to enhance self-management in people with lipoedema using the Intervention Mapping (IM) approach. METHODS: Following the first four steps of the IM approach, this study used a participatory methodology involving stakeholders, empirical data, and theory. Steps included: 1) needs assessment; 2) identification of outcomes, performance objectives, and change objectives; 3) selection of behavioural change methods; and 4) development of program components. RESULTS: The resulting intervention includes a program for people with lipoedema and a training program for healthcare professionals (HCPs). The intervention aims to empower patients to engage in self-management and equip HCPs to provide effective support. Key determinants targeted include self-efficacy, self-regulation skills, knowledge, attitudes, and social facilitation. The program for people with lipoedema consists of seven themes aligned with self-management behaviours and is delivered through 19 sessions: seven one-on-one sessions, one session involving supportive individuals, and 11 group sessions. The program for HCPs is delivered through six group sessions, each focusing on the core skills HCPs need to effectively deliver self-management support to their patients. CONCLUSION: The IM approach effectively guided a systematic, transparent, and reproducible development process. Grounded in established theories and behavioural change methods, the intervention provides a strong foundation for implementation and evaluation among people with lipoedema. The fifth and sixth steps of IM are considered future priorities