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Health care providers' perceptions of family participation in essential care in the intensive care unit: A qualitative study.
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319833.pdf (Publisher’s version ) (Open Access)BACKGROUND: Family participation in essential care may benefit patients and relatives. AIM: To examine the needs, perceptions and preferences of health care providers about family participation in essential care in the adult intensive care unit. STUDY DESIGN: A qualitative descriptive study using inductive thematic analysis. Three focus group interviews with a total of 30 intensive care unit health care providers, consisting of 20 critical care nurses, one nursing assistant, five physicians, three physical therapists and one speech therapist working in three Dutch intensive care units. RESULTS: One overarching theme, balancing interests, and four main themes emerged: looking after the patient's interests, taking the relatives' perspective into account, looking after interests of intensive care unit health care providers and conditions for family participation. The first theme, looking after the patient's interests, included three sub-themes: insecurity about patient's wishes and needs, patient safety concerns and potential benefits for the patient. The second theme, taking the relatives' perspective into account, was also characterized by three sub-themes: concerns about the relatives' possible burden, potential benefits for the relative and the relationship between patient and relative. The third theme, looking after interests of intensive care unit health care providers, included three sub-themes: attitude towards family participation in essential care, differing perceptions of essential care and concerns about intensive care unit health care provider's burden. The last theme, conditions for family participation, included two sub-themes: establishing a relationship and considering family participation in essential care as a process. CONCLUSIONS: Health care providers' perceptions and preferences regarding family participation in essential care in the intensive care unit are summarized in the overarching theme balancing interests. This overarching theme also reflects the needs and perceptions of patients and relatives. RELEVANCE TO CLINICAL PRACTICE: These findings may support critical care nurses and other health care providers when encouraging family participation in essential care
Ethical and Useful Machine Learning for Psychiatry
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319733.pdf (Publisher’s version ) (Open Access)This thesis contributes to computational psychiatry, demonstrating the potential of machine learning to address fundamental challenges of diagnostic subjectivity and biological heterogeneity in mental health research. By advancing normative modeling, a framework for understanding individual deviations from population norms, this work establishes accessible tools to analyze brain health across the human lifespan. The intersection of machine learning methods applied to research questions in psychiatry is viewed from the lens of fairness and accountability, arguing for a paradigm shift in how algorithms are developed and deployed. By advancing the scale, accessibility, validation, and fairness of normative modeling, this work provides a roadmap for ethical and impactful innovation in the field. Ultimately, the work reflects a commitment to interdisciplinary collaboration and social responsibility. Its contributions pave the way for personalized, equitable mental health care that embraces the complexity of human biology and behavior.Radboud University, 17 juni 2025Promotores : Marquand, A.F., Beckmann, C.F., Ruhé, H.G.245 p
A cost-effectiveness study of PSMA-PET/CT for the detection of clinically significant prostate cancer
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320819.pdf (Publisher’s version ) (Open Access)12 maart 202511 p
Schep ruimte voor ingroei van nieuwe waarden in langlopende projecten: Leren van de Oosterscheldekering
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Complete Test Suites for Automata in Monoidal Closed Categories
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319705.pdf (Publisher’s version ) (Open Access)FoSSaCS 2025; ETAPS 202
Learning Latent Profiles via Cognitive Growth Charting in Psychosis: Design and Rationale for the PRECOGNITION Project.
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319650.pdf (Publisher’s version ) (Open Access)BACKGROUND AND HYPOTHESIS: Cognitive impairments are a core feature of psychosis that are often evident before illness onset and have substantial impact on both clinical and real-world functional outcomes. Therefore, these are an excellent target for stratification and early detection in order to facilitate early intervention. While many studies have aimed to characterize the effects of cognition at the group level and others have aimed to detect individual differences by referencing subjects against existing norms, these studies have limited generalizability across clinical populations, demographic backgrounds, and instruments and do not fully account for the interindividual heterogeneity inherent in psychosis. STUDY DESIGN: Here, we outline the rationale, design, and analysis plan for the PRECOGNITION project, which aims to address these challenges. STUDY RESULTS: This project is a collaboration between partners in 5 European countries. The project will not generate any primary data, but by leveraging existing datasets and combining these with novel analytic methods, it will produce multiple contributions including: (i) translating normative modeling approaches pioneered in brain imaging to psychosis data, to yield "cognitive growth charts" for longitudinal tracking and individual prediction; (ii) developing machine learning models for harmonizing and stratifying cohorts on the basis of these models; and (iii) providing integrated next-generation norms, having broad sociodemographic coverage including different languages and distinct norms for individuals with psychosis and unaffected individuals. CONCLUSIONS: This study will enable precision stratification of psychosis cohorts and furnish predictions for a broad range of functional outcome measures. It will be guided throughout by lived experience experts.01 januari 202
Parental numeracy expectations, home numeracy activities, and children's early numeracy skills in mainland China across urban and rural areas
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320385.pdf (Publisher’s version ) (Closed access)Research Findings: This study aimed to examine the relationships between HNE (parental numeracy expectations and home numeracy activities) and children's early numeracy skills, as well as the moderating effect of area level in the relationship between home numeracy activities and early numeracy, were explored. One hundred and eighty-two kindergarten children (Mage = 55.17 months) were assessed on early numeracy skills, and their parents completed a survey on HNE. Results showed that traditional and digital home numeracy activities were significantly associated with children's early numeracy skills. Finally, although no direct or indirect effects from parental numeracy expectations (via home numeracy activities) were found in predicting children's numeracy skills for both area levels, the predictive powers of traditional and digital home numeracy activities on early numeracy were different. Overall, these results suggest that regarding basic numeracy, Chinese parents may attach similar importance to home activities regardless of area, and children could reach a certain level at a young age. Practice or Policy: The digital aspect of home numeracy activities should be included in the home numeracy environment, and exploring the effects of traditional and digital home numeracy activities on the other early mathematic skills, such as arithmetic, spatial skills, and geometry is needed.18 juni 202521 p
From policy to practice: progress towards data- and code-sharing in ecology and evolution
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324127.pdf (Publisher’s version ) (Open Access
A Coach-Supported mHealth Lifestyle Intervention to Reduce Dementia Risk in Persons With Low Socioeconomic Status or a Migration Background: Qualitative Co-Design Study.
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325388.pdf (Publisher’s version ) (Closed access)BACKGROUND: The prevalence and incidence of dementia are higher in migrants and those with low socioeconomic status (SES). Mobile health (mHealth) interventions offer a potentially scalable way to reduce dementia risk via risk factor modification. OBJECTIVE: We co-designed the MIND-PRO app-an mHealth intervention targeting dementia risk factors through self-managed lifestyle changes and remote coaching-specifically designed for Dutch individuals with low SES and those with Turkish or South Asian Surinamese migration backgrounds. We focused on these migrant populations as they are the largest in the Netherlands and have the highest risk of developing dementia. METHODS: In this qualitative study, we explored the needs and preferences of our target populations aged 50-75 years old at increased dementia risk by conducting semistructured interviews and focus groups. Participant feedback was used to iteratively refine and adapt a prototype intervention based on insights from prior mHealth trials. RESULTS: We interviewed 23 participants (median age 59, IQR 55-63 y; n=15, 65% female) and conducted two focus groups with 7 Turkish women and 13 Dutch participants with low SES. The target populations emphasized personalization features such as goal setting, self-tracking, educational material, and remote coaching. Participants highlighted the importance of social interaction and autonomy in achieving sustainable lifestyle changes. Tailoring coaching and lifestyle advice to cultural practices was deemed beneficial. CONCLUSIONS: Optimal mHealth interventions targeting dementia risk factors in migrants and individuals with low SES should be personalized and interactive, respect autonomy, and integrate cultural needs and preferences
Macro-economic inequality and national stereotypes in 45 non-Western countries
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324238.pdf (Publisher’s version ) (Closed access)The assumption that people favor ingroups and disfavor outgroups is based largely on theory and research from Western countries. However, groups subjected to economic exploitation and inequality might come to favor more advantaged outgroups. The present large-scale study (N = 12,339) involving 45 non-Western countries explored ingroup stereotypes and stereotypes of relatively advantaged and disadvantaged outgroups (Western Europeans and Western Africans, respectively) and their relation to macroeconomic conditions. Compared with their national ingroup, participants stereotyped advantaged outgroups as more competent (exhibiting outgroup favoritism) but less warm; they stereotyped disadvantaged outgroups as less competent but neither more nor less warm. Nationals of poorer and more exploited countries exhibited stronger outgroup favoritism on competence and stronger ingroup favoritism on warmth. This work provides preliminary evidence for the structural origins of national stereotypes: macroeconomic inequalities can override habitual ingroup favoritism and lead national groups to exhibit outgroup favoritism.11 september 202518 p