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Diagnostic Accuracy of 4D-MRA for the Detection and Localization of Spinal Dural Arteriovenous Fistulas: A Systematic Review and Meta-Analysis.
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316837.pdf (Publisher’s version ) (Open Access)BACKGROUND: The gold standard for the diagnosis and detailed evaluation of spinal dural arteriovenous fistula (SDAVF) is a digital subtraction angiography (DSA). However, this procedure is time-consuming and effortful. A time-resolved contrast enhanced 4D magnetic resonance angiography (4D-MRA) can be used to increase the diagnostic accuracy of spinal magnetic resonance imaging for the detection and localization of a SDAVF. The goal of this study is to assess the diagnostic accuracy of 4D-MRA for the detection and localization of a SDAVF in comparison to DSA based on a systematic review of the literature. METHODS: We performed a systematic review and meta-analysis on the diagnostic accuracy of 4D-MRA compared to DSA. Literature was reviewed from the PubMed, Cochrane, and EMBASE databases. RESULTS: In comparison with DSA, the pooled sensitivity of MRA was 98.2% (95% confidence interval [CI] 91.5%-99.6%), with a pooled specificity of 88.2% (95% CI 57.5%-97.6%) for the diagnosis of SDAVFs. The side and level of the SDAVFs were correct in 91% (95% CI: 86%-94%) and 76% (95% CI: 71%-80%), respectively. CONCLUSIONS: Current literature indicates that 4D-MRA has a high sensitivity and specificity for the detection and localization of a SDAVF. It can serve to guide DSA to shorten the procedural time, reduce the risk of complications, and decrease patient discomfort.01 januari 202
BCG-Induced DNA Methylation Changes Improve Coronavirus Disease 2019 Vaccine Immunity Without Decreasing the Risk for Severe Acute Respiratory Syndrome Coronavirus 2 Infection
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316205.pdf (Publisher’s version ) (Open Access
The Southern Twenty-centimetre All-sky Polarization Survey (STAPS): Survey description and maps (2025)
No full textItem does not contain fulltextWe present data processing and verification of the Southern Twenty-centimetre All-sky Polarization Survey (STAPS) conducted with Murriyang, the Parkes 64-m telescope. The survey covers the sky area of -89{deg}<Dec<0{deg} and the frequency range of 1.3-1.8GHz split into 1-MHz channels. STAPS was observed commensally with the S-band Polarization All-Sky Survey (S-PASS). The survey is composed of long azimuth scans, which allows us to absolutely calibrate Stokes Q and U with the data processing procedure developed for S-PASS. We obtained I, Q, and U maps on both the flux density scale (Jy/beam) and the main beam brightness temperature scale (K), for the 301 frequency channels with sufficiently good data. The temperature scale is tied to the Global Magneto-ionic Medium Survey (GMIMS) high-band north sky survey conducted with the Dominion Radio Astrophysical Observatory 26-m telescope. All the STAPS maps are smoothed to a common resolution of 20'. The root mean square (rms) noise per channel ranges from about 16mK to 8mK for I, and from about 8mK to 5mK for Q and U, at frequencies from 1.3 to 1.8GHz. The rms noise in Q and U varies with declination and reaches minimum at declination of -89{deg}. We also ran rotation measure (RM) synthesis and RM clean to obtain peak polarized intensity and Faraday depth maps. The whole STAPS data processing was validated by comparing flux densities of compact sources, pixel flux density versus pixel flux density for Cen A, pixel temperature versus pixel temperature for the entire survey area, and the RMs of extragalactic sources between STAPS and other measurements. The uncertainty of the flux density scale is less than 10%. STAPS delivers an L-band ({lambda}20cm) multifrequency polarization view of the Galaxy, and will help advance our understanding of the Galactic magnetic field and magnetized interstellar medium
Auditory working memory in noise in cochlear implant users: Insights from behavioural and neuronal measures.
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315961.pdf (Publisher’s version ) (Open Access)OBJECTIVE: We investigated auditory working-memory using behavioural measures and electroencephalography (EEG) in adult Cochlear Implant (CI) users with varying degrees of CI performance. METHODS: 24 adult CI listeners (age: M = 61.38, SD = 12.45) performed the Sternberg auditory-digit-in-working-memory task during which EEG, accuracy, and promptness were captured. Participants were presented with 2, 4, or 6 digits at Signal-to-Noise Ratios (SNR) of 0, +5 and +10dB. They had to identify a probe stimulus as present in the preceding sequence. ANOVA models were used to compare conditions. RESULTS: ANOVA revealed that increasing memory load (ML) led to decreased task performance and CI performance interacted with ML and SNR. Centro-parietal alpha power increased during memory encoding but did not differ between conditions. Frontal alpha power was positively correlated with accuracy in conditions most affected by SNR (r = 0.57, r = 0.52) and theta power in conditions most affected by ML (r = 0.55, r = 0.57). CONCLUSIONS: While parietal alpha power is modulated by the task, it is frontal alpha that relates quantitatively to sensory aspects of processing (noise) and frontal theta to memory load in this group of CI listeners. SIGNIFICANCE: These results suggest that alpha and theta show distinct relationships to behaviour, providing additional insight into neurocognitive (auditory working-memory) processes in CI users.01 februari 202
Understanding patterns of engagement in the citizen humanities. The civil records of Suriname
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312105.pdf (Publisher’s version ) (Open Access)16 p
Incidence of Newly Diagnosed Cancer After Cerebral Venous Thrombosis.
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316635.pdf (Publisher’s version ) (Open Access)IMPORTANCE: Active cancer is a risk factor for cerebral venous thrombosis (CVT), but whether CVT is associated with occult cancer is unknown. OBJECTIVE: To evaluate the incidence of newly diagnosed cancer after CVT. DESIGN, SETTING, AND PARTICIPANTS: This population-based cohort study used data from the Dutch Hospital Discharge Registry from January 1, 1997, to July 1, 2020. Analyses were conducted between June 2023 and April 2024. Patients admitted with a first-ever CVT were included. Patients with a history of cancer or diagnosed with cancer during hospitalization for CVT were excluded. EXPOSURE: CVT was identified using International Classification of Diseases, Ninth Revision (ICD-9) and International Statistical Classification of Diseases and Related Health Problems, Tenth Revision (ICD-10) codes. MAIN OUTCOMES AND MEASURES: The main outcome was cumulative incidence of cancer after CVT. Standardized incidence ratios (SIRs) were calculated relative to a matched cohort from the general population using the Netherlands Cancer Registry. RESULTS: A total of 2649 patients with CVT (median [IQR] age, 44.5 [30.7-56.4] years; 1856 [70.1%] female) were included. Cancer was diagnosed in 119 patients during a median (IQR) follow-up of 4.7 (1.9-8.9) years, of whom 29 (24.4%) had hematologic cancer. The cumulative incidence of cancer was 5.9% (95% CI, 4.8%-7.2%) after 10 years and was highest in men aged 50 years or older (13.5%; 95% CI, 9.1%-18.7%). Patients with CVT had an increased rate of cancer compared with the reference cohort during the entire follow-up, but the difference narrowed over time (SIRs of 3.35 [95% CI, 2.41-4.55] and 1.40 [95% CI, 1.14-1.69] at 1 and 10 years, respectively). The rate was increased both in patients younger than 50 years (SIRs of 6.70 [95% CI, 3.97-10.59] and 1.72 [95% CI, 1.24-2.34] at 1 and 10 years, respectively) and those 50 years or older (SIRs of 2.41 [95% CI, 1.53-3.62] and 1.25 [95% CI, 0.96-1.60] at 1 and 10 years, respectively), as well as in male patients (SIRs of 3.59 [95% CI, 2.16-5.61] and 1.69 [95% CI, 1.25-2.23] at 1 and 10 years, respectively) and female patients (SIRs, 3.17 [95% CI, 1.99-4.80] and 1.22 [95% CI, 0.92-1.58] at 1 and 10 years, respectively). CONCLUSIONS AND RELEVANCE: This cohort study of patients with CVT found an increased risk of cancer during follow-up regardless of age or sex. Men 50 years or older had the highest absolute risk, whereas younger patients had the highest relative risk. Physicians should be vigilant for signs of cancer after CVT, and further research on screening for cancer after CVT is warranted
Cost-effectiveness of low-dose colchicine in patients with chronic coronary disease in The Netherlands
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315621.pdf (Publisher’s version ) (Open Access
Highlights of the Cardiovascular Magnetic Resonance 2024 Conference: the first joint European Association of Cardiovascular Imaging, European Society of Cardiovascular Radiology, and Society for Cardiovascular Magnetic Resonance conference.
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318068.pdf (Publisher’s version ) (Open Access)Cardiovascular Magnetic Resonance 2024 Conference (CMR2024) convened in London, UK, from 24 to 26 January 2024 and brought together 2705 learners and renowned cardiac imaging professionals to discuss and learn about the latest advancements. Organized by the Society for Cardiovascular Magnetic Resonance (SCMR) and the European Association of Cardiovascular Imaging (EACVI), in collaboration with the European Society of Cardiovascular Radiology (ESCR), CMR2024 was the largest international cardiac magnetic resonance conference to date. This conference underscored the collaboration between cardiologists, radiologists, scientists, and technologists by bringing together three major societies-SCMR, EACVI, and ESCR. Innovative session formats like 'Shark Tank' and 'Workflow, Innovations & Patients' facilitated expert opinion and practical experiences sharing in a 'TED-talk style'. With over 1168 abstract submissions and 75% acceptance rate, the programme featured multiple Early Career Award sessions, oral scientific sessions, oral case sessions, and rapid-fire sessions, all categorized by topic. Highlights included patient- and physician-centred imaging sessions, sharing referring physicians' and patients' insights of incremental value of cardiovascular magnetic resonance (CMR) in patient's management. The programme offered invited lectures in eight parallel tracks with three plenary and two keynote speakers. In addition, the interactive workshops and panel discussions provided a platform for knowledge exchange, support, and collaboration. A great emphasis was placed on collaboration between radiologists, cardiologists, scientists, and technologists, showcasing an ideal cardiac imaging marriage as a model for enhanced patient care around the globe. The event also featured exhibitions of the latest CMR technology and software, offering attendees a glimpse into the future cardiac imaging. CMR2024 emerged as a remarkable scientific, educational, and networking event, inspiring attendees to learn and collaborate within the global CMR community