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Effectiveness of Therapeutic Interventions in the Treatment of Internet Gaming Disorder: A Systematic Review
Internet Gaming Disorder (IGD) has been recognized by the World Health Organization (WHO) in the International Classification of Diseases (ICD-11) and as an emerging condition in the DSM-5. IGD is increasingly prevalent, with various negative effects on individuals’ development and adaptation. To address this issue, different therapeutic interventions, like CBT, virtual reality, mindfulness, or family therapy, have been explored. This systematic review aimed to answer the following research question: What is the effectiveness of therapeutic interventions in reducing IGD symptoms in adolescents and young adults diagnosed with this disorder? Following PRISMA guidelines, 22 studies published between 2014 and 2025 were included. Results show that cognitive behavioral therapy (CBT) is the most effective intervention, significantly reducing IGD severity, anxiety, and depression. Combining CBT with physical exercise or mindfulness further enhanced outcomes. Other promising approaches include virtual reality (VR), transcranial direct current stimulation (tDCS), and family-based interventions. Additionally, treatments involving mindfulness and animal-assisted therapy showed potential in improving emotional regulation and interpersonal relationships. However, further research is needed to evaluate long-term efficacy and explore emerging therapies
Predicting rheological properties of HAMA/GelMA hybrid hydrogels via machine learning
- Rheological properties are pivotal in determining the printability of biomaterials, directly impacting the success of 3D bioprinted constructs. Understanding the intricate relationship between biomaterial formulations, rheological behavior and printability can facilitate the advancement and rapid development of biomaterials. Herein, we critically measured the rheological properties of hyaluronic acid methacrylate (HAMA)/gelatin methacrylate (GelMA) hybrid hydrogels with varied formulations and generated a dataset to train a machine learning (ML) model. By utilizing four well-known algorithms, we developed the ML model for the viscosity and shear stress of HAMA/GelMA hydrogel mixtures. To improve model interpretability, we further created a multilayer perceptron framed model, known as HydroThermoMLP, by incorporating the Redlich-Kister polynomial as the thermodynamic representation of viscosity of mixtures. To accomplish the MLP learning on limited data, the shared loss function was formulated on the basis of the R-K presentation to guide the joint training process. The established HydroThermoMLP model, while maintaining the same accuracy as Random Forest, produces outputs that adhere to thermodynamic constraints and instill confidence in generalization applications with a simple algorithm informed by the R-K polynomial. It presents a robust predictive ML tool to forecast the viscosity of hybrid hydrogels and direct the design of biomaterials while appropriately abiding by thermodynamic constraints as essential guidelines
Intervención protésica de terapia ocupacional en personas con amputación transradial: una revisión de alcance
Esta revisión consiste en identificar las intervenciones mayormente llevadas a cabo por la terapia ocupacional en personas con amputación transradial, el impacto de dichas intervenciones sobre la persona amputada, las principales prótesis utilizadas por personas con amputación transradial y explorar la evolución de la tecnología protésica moderna durante los últimos 10 años.<br /
Evaluación y tratamiento funcional tras fracturas complejas y artrodesis: a propósito de un caso
Introducción: Este estudio analiza el caso de un paciente de 35 años con artrodesis de tobillo previa y fracturas complejas recientes en ambas piernas. Se plantea que un programa de ejercicios de fuerza y funcionales puede mejorar su marcha, calidad de vida y funcionalidad general.Metodología: Se realizó un estudio de caso único (n=1) con diseño longitudinal pre-post intervención. Durante 5 semanas, el paciente siguió un programa individualizado de ejercicios de fuerza y funcionales, con análisis antes y después del tratamiento. Para analizarlo, se utilizaron cuestionarios (SF-36, FAAM), pruebas funcionales (TUG, 10MWT, test de Flamenco, Sit to Stand), análisis de marcha en 3D con ModelHealth® y pruebas de fuerza máxima.Resultados: Se observaron mejoras en todos los parámetros: reducción en los tiempos del TUG y 10MWT, aumento de repeticiones en pruebas funcionales, mayor fuerza en extremidades inferiores y una marcha más simétrica y eficiente, además de mejorar en las puntuaciones en SF-36 y FAAM.Discusión: Un tratamiento fisioterapéutico personalizado y progresivo basado en ejercicio de fuerza puede acelerar la recuperación incluso en casos complejos. Se observó una mejoría tanto objetiva (fuerza, movilidad) como subjetiva (percepción de funcionalidad). ModelHealth® demostró ser una herramienta útil para el análisis biomecánico, aunque con limitaciones en ciertas mediciones angulares.Conclusión: El ejercicio terapéutico individualizado generó mejoras funcionales significativas. Herramientas tecnológicas accesibles como ModelHealth® pueden complementar eficazmente la fisioterapia tradicional, facilitando el seguimiento del paciente.<br /
Plan de intervención de ejercicio terapéutico en paciente oncológico post-intervención de oligodendroglioma. A propósito de un caso
Introducción: Los oligodendrogliomas son tumores cerebrales de infiltración difusa y originados por una interacción multifactorial, de crecimiento lento y buen pronóstico, pero su tratamiento puede generar secuelas. El objetivo de este estudio fue aplicar un plan de entrenamiento basado en el ejercicio terapéutico en un paciente oncológico que ha recibido un tratamiento multifactorial. Metodología: Se diseñó un estudio de caso único, descriptivo y longitudinal, aplicado a un paciente varón de 63 años. Se diseñó un programa de 12 semanas con evaluación funcional pre y post intervención. El plan incluyó entrenamiento de fuerza, ejercicio aeróbico, técnicas respiratorias y ejercicios de equilibrio. Resultados: La evaluación final mostró el descenso de la tensión arterial y frecuencia cardíaca en reposo, aumento del FEV1/FVC, ligera ganancia de masa muscular y fuerza y mejora en el equilibrio. También se observaron mejoras claras en percepción de salud, energía, dolor y calidad de vida. Discusión y conclusión: Tras la aplicación de un programa de ejercicio físico combinado, se observaron mejoras en variables fisiológicas y psicosociales. Se destacó especialmente la desaparición del patrón obstructivo respiratorio y el aumento de la fuerza dentro de valores normativos. No obstante, al tratarse de un caso único y de corta duración, los resultados no son generalizables ni permiten evaluar efectos a largo plazo. <br /
Plan de intervención en síndrome del desfiladero torácico: a propósito de un caso
Introducción:El síndrome del desfiladero torácico (SDT) es una patología caracterizada por la compresión del plexo braquial, arteria y vena subclavias en el espacio torácico. Es un síndrome de etiología multifactorial, con factores tanto estructurales como dinámicos, y con sintomatología variable en función del tipo de SDT que presente el paciente.Objetivo del estudio:Diseñar y realizar un plan de intervención de fisioterapia para un caso clínico de un paciente que presenta SDT de tipo neurogénico, con el objetivo principal de disminuir la mecanosensibilidad del plexo braquial, realizando una evaluación completa mediante inspección estática y dinámica, evaluación neurológica y muscular, evaluación de la mecanosensibilidad mediante test neurodinámicos de nervios periféricos, test ortopédicos específicos para el SDT (Adson, Wright y Roos), palpación y cuestionarios de función.Metodología:El plan de intervención dura seis semanas y se basa en la realización de movilizaciones neurales, terapia manual, ejercicios de estiramiento y fortalecimiento de la cintura escapular, incidiendo en la educación acerca de la correcta postura y ergonomía en actividades laborales, de ocio y deportivas.Resultados:Tras las seis semanas de intervención se refiere una notable mejoría en la sintomatología del paciente, control escapular y calidad de vida.Conclusión:El plan de intervención planteado consigue disminuir la mecanosensibilidad neural que padece el paciente, mejorando también la tensión muscular, el control escapular y la postura y ergonomía durante las actividades cotidianas.<br /
A Circular Economy Balance Scorecard Framework for Agrifood Companies in Emerging Economies
The agrifood sector provides several opportunities to promote circular economy (CE) mitigating and preventing its adverse environmental impacts. To evaluate the effects of CE in practices and to ensure consistency with business strategies, the implementation of circularity principles requires the adaptation of current performance management systems. The objective of this research is to contribute to the successful implementation of corporate strategies for circularity through the development of a circular balanced scorecard (CBSC) including the construction of data set of specific CE strategies and indicators for agrifood companies in emerging economies. To this end, a systematic review of the literature was carried out to construct the data set and develop the CBSC. The framework offers a theoretical and practical PMS that could help agrifood companies in emerging economies start their circular journey, providing guidance for the definition of CE strategies and the selection of proper indicators to monitor success
What role do orthorectic beliefs play in orthorexia nervosa and healthy orthorexia? Development and validation of the Orthorexia Beliefs Scale (OBS)
Cognitive models of obsessive-compulsive disorder (OCD) postulate that dysfunctional beliefs and appraisals are key elements in the development and maintenance of obsessions. Given the relationship between the orthorexia nervosa (OrNe), OCD, and eating disorders, it is not surprising that some dysfunctional beliefs are present in OrNe. The aim of this research was to determine the relevance of dysfunctional beliefs in OrNe. To do so, we developed and validated an instrument that assesses these beliefs –the Orthorexia Beliefs Scale (OBS)– and, subsequently, analyzed the association between orthorexia, food restriction, obsessive-compulsive symptoms, and negative/positive affect, along with the beliefs evaluated with the OBS. Participants (n = 418) were given a set of questionnaires. We expected the obtained instrument to be able to assess dysfunctional beliefs related to orthorexia and establish positive associations between pathological dimensions and OrNe. The results revealed that the scale evaluated three factors: Overvaluation of Healthy Eating, Moral Meaning, and Need to Control. OrNe was significantly associated with all three of these factors and the most relevant association was with the Need to Control factor. An association between the non-pathological variable of orthorexia (HeOr) and the Overvaluation of Healthy Eating factor was also found. The results seem to indicate that the dysfunctionality of orthorexia is highly marked by the need to control, as also occurs in eating disorders
The hydrophilic nature trade-off of supported ionic liquid membranes on CO2/CH4 separation performance
Biomethane has been highlighted as an energy transition carrier in the quest for a resilient bioeconomy. Advances in its production process are accompanied by the need for new efficient separation methods for purification and carbon capture. However, biogas is fully saturated with water, jeopardising the expected performance of proposed novel materials. In this work, imidazolium-based Supported Liquid Membranes (SLM) with different hydrophilicity levels were proven to separate mixed CO2/CH4 successfully. IL-based SLMs were assessed in terms of stability, transport kinetics, and phase equilibria. Gas diffusion in dry and humid environments was estimated using the time-resolved FTIR-ATR spectroscopy technique. Henry's law constants of CO2 and CH4 and molecular interactions were estimated using the quantum chemical COnductor like Screening MOdel for Real Solvents (COSMO-RS) method. The SLM stability diagram is proposed to represent the effect of the gas water content on the total filled pores as a function of the components' physicochemical properties, support morphology, and operational pressure gradient. Diffusion coefficients of CO2 in the hydrophilic SLMs are substantially altered under wet environments. However, it has been shown that gas solubility mainly dominates the gas separation. The SLM's water sorption increases this effect by further rejecting methane. While the membrane hydrophilicity improves the gas selectivity, its stability diminishes in humid gas processing. The trade-off between the separation performance using highly hydrophilic solvents and the SLM module stability under real and variable conditions of pressure and humidity constrains the technology feasibility. Therefore, its study must be considered in the development and application of SLMs in sustainable biofuel production routes
Gigantomastia: Advancing a Preference Score System to Enhance Care Quality and Life Standards
This study introduces a new Gigantomastia Preference Score (GPS) to prioritize surgical candidates based on clinical severity and quality of life impact.Methods.This retrospective study applied the newly developed GPS to the existing surgery waiting list of 213 patients at our center. The GPS was developed from evidence-based clinical practice indicators and a thorough literature review, selecting nine variables. The GPS was then used to reorder the waiting list, and comparisons were made between the original and reordered lists.
Results. Implementation of the GPS significantly reordered the waiting list. The Spearman's Rank Correlation coefficient between the original and new rankings was 0.5679 (p-value = 1.38e-19), indicating a moderate to strong positive correlation. The Wilcoxon Signed-Rank Test yielded a statistic of 3485.0 (p-value = 8.44e-21), showing significant changes in patient positions. ANOVA results highlighted significant differences in BMI and largest breast weight across priority levels. Chi-Square tests revealed significant associations between priority levels and Trauma and Psychiatry reports.
Conclusions. The GPS significantly improved the prioritization of patients with gigantomastia by incorporating multiple clinically relevant factors. This led to a more equitable and informed ordering of the surgical waiting list, potentially improving patient outcomes and optimizing healthcare resource allocation.Level of Evidence IV. This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.