Journal of Ayurveda and Holistic Medicine (JAHM)
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A CASE STUDY ON THE MANAGEMENT OF TAMAKA SHWASA IN CHILDREN WITH POLYHERBAL FORMULATION
Asthma is a non-communicable chronic lung disease, characterized by airway inflammation, airway obstruction mainly due to muscle spasm, associated with edema and stagnation of the mucus, Airway hyper-reactivity to aerobiological and irritants, airway remodeling in uncontrolled asthma. Ayurveda texts have described five types of Shwasa Roga and among them five, Tamaka Shwasa (Bronchial Asthma) is one which is a “Swatantra Vyadhi (independent disease) having its own etiological factor, patho-physiology and management. It is mentioned as Yapya Vyadhi (palliative disease) in Charaka Samhita, while Sushruta considered it as Krichchra Sadhya Vyadhi (difficult to cure disease).Tamaka Shwasa is basically a disorder of Praanavaha Srotasa while other Srotasa are also vitiated. The present effort is intended to study the efficacy of such formulations in reducing the sign and symptoms of childhood asthma. A case of 12 year old male patient who presented features of Tamaka Shwasa was treated by internal Ayurvedic Medicine; Shwasahara Dashemani Churna showed marked improvement in cardinal feature such as breathlessness, cough, awakening in night etc. and some hematological Parameters, discussed here. After 8 weeks of Follow up no episodes of above complaints have been reported
A Comparative Clinical Study of Madhoodak & Gomutra-Arka as Pathya in Atisthaulya w.s.r. to Obesity: Role of Madhoodak & Gomutra Ark in Sthaulya or obesity
Overweight and obesity are the fifth leading risk for global death. It is a major risk factor for serious non-communicable diseases, such as CVD, hypertension, stroke, DM etc. Various medicines are available for the management but results are unsatisfactory and prevention is the only alternative. It is told that there is no other medicine as diet. So there is a need to find a suitable measure for this purpose. To assess the efficacy of Madhoodak & Gomutra Arka in the management of Sthaulya & compare their effect. In present clinical trial 40 patient aged between 20 to 45 years, reporting BMI in between 25 to 40 kg/m2, having clinical signs and symptoms of Sthaulya were selected from O.P.D. & I.P.D. & Yoga Unit of NIA Hospital, Jaipur, Rajasthan, and registered following written consent. Registered patients were randomly divided into two groups. Group A has been administered with Gomutra Arka & Group M has been administered with Madhoodak , once in a day. Follow up has been recorded after every fortnight for the duration of 3 month. The efficacy of therapy was assessed on the basis of various subjective & objective criterion such as Chala Sphika-Udara-Stana, Alasya, Kshudrashwasa, Daurbalya,Weight, BMI & circumference measurements,S. Cholesterol, S. Triglyceride, HDL, LDL and VLDL etc. Both the groups showed statistically highly significant (p<0.001) results in all the Subjective, Objective, Anthropometric & Laboratorial parameters except in Alpa vyavaya & Gatra sada. Group A showed better percentage of relief in maximum parameters except in Daurbalya, Atipipasa, Atikshudha, & Alpavyavaya. These are the only symptoms in which Madhoodak Group showed maximum percentage relief.The Gomutra Arka & Madhoodak both are safe, cost effective and free from side effects & can be used for effective management of Sthaulya and in comparison Gomutra Arka is better
CLASSICAL ASHTAVAIDYAN AYURVEDIC THERAPY IN THE FUNCTIONAL IMPROVEMENT OF PATIENTS WITH ANKYLOSING SPONDYLITIS: AN OPEN LABEL, SINGLE ARM CLINICAL STUDY
Background:Ankylosing spondylitis is a chronic, systemic, inflammatory disease that affects primarily the sacroiliac joints and spine with the symptoms of muscular spasm, stiffness and limitation of movement of spine. Traditional practice of Ashtavaidyan Ayurveda line of management has been tried to evaluate the efficacy in ankylosing spondylitis. A combined treatment with internal medication and external therapeutic procedures has been taken up to assess the evaluate the effect on the functional improvement and safety in ankylosing spondylitis. Methodology: Diagnosed cases of ankylosing spondylitis (n=30) (20-60 yrs) have undergone the prescribed classical AshtavaidyanAyurvedictherapy; the total study period was 57 days which included 21 days each at inpatient and outpatient basis and 15 days of follow up. Initially Pizhichil with KetakeemooladiTaila with PanchatiktakaGhrita was performed along with internal medications for first 7 days later same internal medication is continued with SathailaTilaPindaSweda and followed by PanchatikthakaKsheeraBasti for last 7 days. Same internal medicines and oil application were continued for next 21 days on outpatient basis and BalaguluchyadiTaila was applied regularly on scalp for all these days. Result: The response of treatment was assessed periodically with respective parameters and was showed significant improvement. The functional improvement was evaluated by using the BASDAI score, DAS-28 score, disability index, SF-36 and global assessment of disease activity scale and there were significant changes in all the above scales. The laboratory parameters used to evaluate the liver and kidney functions did not show any significant change that indicates the prescribed treatment is safe. Conclusion: Traditional Ashtavaidyan Ayurveda therapy iss effective in improving functional ability in Vatarakta vis-à-vis ankylosing spondylitis over a period of 42 days. Moreover, there was no adverse drug reaction recorded during as well there was no significant change observed in liver and renal function tests.
Keywords: Ayurveda, ankylosing spondylitis, Vatarakta, Pizhichil, GandarvasthadiKashaya, KethakeemooladiTaila, KsheeraBasthi, HLA-B2
CONCEPT OF DOSHA DUSHYA SANGRAHA AND DHATU SHAITHILYA (FLACCIDITY OF BODY CONSTITUENTS): THEIR IMPORTANCE IN DIAGNOSIS, TREATMENT AND PROGNOSIS OF PRAMEHA
Background: Pathology of Prameha mentioned in classics is succinct and needs reading between the lines to appreciate its explicit and indubitable details. Bahu Drava Shleshma (Kapha in more liquid state) causes Prameha, but it is also caused due to other Dosha. Bahu Abadhda Meda and Mamsa (increased Meda and Mamsa with flaccidity) are undoubtedly principal Dushya, but role of other Dushya in pathology is unclear. General symptom of Prameha is Prabhuta Avila Mutrata (excess urine with turbidity), but in practice symptoms seen in patients are diverse and alter from time to time. Twenty types of Prameha are mentioned according to different characteristics of urine, but other symptoms according to specific types are not described. To address the issue elaboration of available information about Prameha is necessary. Methods: Literary review of Prameha mentioned in Bruhattrayi, Laghutrayi and Shabdakosha (dictionaries/word repositories) was taken. References were hand searched. Key words related to pathology of Prameha were used.Results: Pathology of Prameha can be elaborated in better way if the two concepts namely – ‘Dosha Dushya Sangraha’ and ‘Dhatu Shaithilya (flaccidity of body constituents)’ are explained. Together, they highlight Anusangitva (recurring nature) of the disease. Conclusion: Application of these concepts in practices can help in understanding prognosis, treatment plans and absolute cure if possible. It also unveils the road ahead in research in Prameha
FORMULATION OF SWARNAMRITAPRASHANA - A NOVEL AYURVEDA ELECTUARY
Swarnamritaprashana, is a modified form of lehana (traditional gold licking) namely Swarnaprashana. Children aredelicate by nature and have immature immune mechanisms. Swarnprashana practiced in yester years was specific to boostoverall health, activate immunity and with a specific goal to achieve any of memory, intellect, voice, complexion, betterdigestive capacity etc. Thus, the selection of herbal medicine in Lehana was condition specific. Traditionally,swarnaprashana is administered by rubbing gold on stone with little water and mixing with ghee and honey.Swarnamritaprashana is a lickable poly herbal formulation in the base of ghee and honey with Gold in the form of bhasma(calcined ash). It is developed to avoid the exercise of daily rubbing, mixing and most importantly to suit the healthconcerns of children. Broad spectrum actions of Swarnamritaprashana may be attributed to its constituent’s namelyMandukaparni (Centella asiatica), Shankhapushpi (Convolvulus pluricaulis), Yashtimadhu (Glycyrrhiza glabra), Amrita(Tinospora cordifolia), Vacha (Acorus calamus), Jatamansi (Nardostachys jatamansi) along with Ashvagandha (Withaniasomnifera), Pippali (Piper longum) and Swarna Bhasma (incinerated gold), ghee and honey. This can be readilyadministered to child in the required dose. This article highlights the ingredients, method of preparation, and probablemechanism of action along with pilot researches that upheld nootropic, growth and development promoting, immunepromoting, recurrent respiratory illness prevention activity of Swarnamritaprashana
A COMPARATIVE STUDY ON THE EFFICIENCY OF PATOLADI GHRITA PANA AND PUNARNAVADHI ANJANA IN TIMIRA
Background: Senile cataract is an age related vision threatening disease. It affects 12 to 15 million persons worldwide. In India approximately 3.38 million persons become blind from cataract every year. Senile immature cataract closely resembles the symptoms of Timira involving Prathama and Dwithiya patala. At present there is no time tested and proven medical treatment to delay, prevent or reverse the development of senile cataract. The present research work is aimed to evaluate easy, cost effective and prevent the deterioration of sight. Aims: To evaluate the efficacy of Patoladi ghrita pana and Punarnavadi anjana in the management of Timira. Methods and Material: It isarandomized non-controlled parallel arm clinical study. A total of 40 patients who are fulfilling the diagnostic and inclusion criteria were selected randomly and allotted in to 20 patients in each group. Group ‘A’ patients weretreated with Patoladi gritha internally and Group ‘B’patients were treated with Punarnavadi Anjana external application. Statistical analysis used: The data were graded based on standard methods and analyzed statistically using Paired’t’and Unpaired’t’tests. Results: Both the groups have shown statistically significant results. Group B patients showed better response when compared to group A. Conclusion: Both medicines were found to be effective in reducing the severity of the symptoms but were not sufficient enough to improve the visual acuity to higher extent and density of opacity. Patients with immature cataract with short duration showed better response when compared to that of longer duration
PHARMACOLOGICAL ACTION OF VISHAGHNA DRAVYAS FROM CHARAKOKTA MAHAKASHAYA IN DRUG INDUCED HEPATOTOXICITY W.S.R. TO GARAVISHJANYA SHOTHA – A REVIEW
Most of the metabolic processes including detoxification of various drugs and xenobiotics occur in the liver. During the detoxification process the reactive chemical intermediates damage the liver. Drug induced hepatotoxicity causes liver damage due to oxidative stress. Hepatotoxicity is an injury to the liver that is associated with impaired liver functions and is a major concern at present. In this modern era, herbal antioxidants have attracted the researches due to its potential and efficacy against drug induced liver injury. Ayurveda describe Vishaghna dravyas as they possess the property to pacify the visha (Toxin) and prevent the reoccurrence of toxic manifestations. Hepatoprotective and Antioxidant activity of Vishaghna Dravyas in Charakokta Mahakashaya has been reported. Most of the Vishaghna dravyas shows pharmacological actions like Shothaghna, Raktashodhaka, Tridoshashamaka, Pittashamaka etc. Drug induced hepatotoxicity can be correlated with the concept of Garavisha in ayurveda. Shotha is one of the manifestations found in Garavisha as well as DIH. Hence Vishaghna dravyas in Charakokta Mahakashaya can be useful in Garavishajanya Shotha and DIH. This review article is an attempt to discuss role of Vishaghna dravyas from Charakokta Mahakashaya as Antioxidant and Garavishaghna in oxidative stress induced hepatotoxicity with special reference to Garavishjanya Shotha