Journal of Ayurveda and Holistic Medicine (JAHM)
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Pharmaceutical Study on Brihat Madhusnuhi Rasayana and Its Organoleptic Evaluation
No full textBrihat Madhusnuhi Rasayana is a classical formulation mentioned in Sahasrayoga under Lehya kalpana.Madhusnuhi is the prime drug in this recipe followed by other important ingredients like Shuddha gandhaka-Shuddha guggulu etc which are known for their good kushtaghna-twachya-rasayana and shoolahara effects. Due to its dosage form of Lehya, it further adds up the rasayana properties due to significant amount of ghee and sugar candy; thus the formulation becomes most apt top administer in chronic diseased conditions of various conditions like chronic wounds and ulcers, degenerative arthritis, steroid dependent skin diseases, non healing ulcers, fistula and sinus conditions etc. The formulation was prepared to evaluate its pharmaceutical feasibility, organo-leptic evaluation and hence to find out the possibilities to large scale manufacturing and hence marketing
STUDY OF JATHARAGNI (DIGESTIVE FIRE) COMPUTED THROUGH NADI PARIKSHAN USING NADI TARANGINI AS PER RUTUS (SEASONS) QUOTED IN THE AYURVEDA TEXTS.: AN OBSERVATIONAL STUDY
No full textBackground: The world is one holistic entity where everyone is viewed in relation to the surrounding environment. The direction of the sun’s movement makes the season-wise different periods and has effects on our body, mind and circadian rhythms in terms of our daily work, food habits, digestion, and metabolism. Ayurveda, the ancient science of wisdom, provides answers for these effects and influence on our health through rutucharya (seasonal regimen). Objectives: to study the correlations between jatharagni, ahar (food) and rutucharya for different prakrutis (body constitution). Materials and methods: We used nadi parikshan (pulse based examination), one of the most popular methods of ashtavidha pariksha (eight fold clinical examination). We observed jatharagni (digestive fire) computed through Nadi Tarangini[1,2] (a commercial wrist nadi recording system) throughout the year and further studied it as per the rutus described in Ayurveda. Results: For 25437 subjects, we found the digestive jatharagni to be low in the monsoon, high in the winter, and also have dominance with vishamagni (irregular fire), tikshnagni (strong/sharp fire) and mandagni (weak/less fire) for vata, pitta and kapha prakrutis respectively. Conclusion: We emphasised the evidence and importance of jatharagni in rutucharya to avoid lifestyle oriented disorders
ALCOHOL: A POTENT ANCIENT ANESTHETIC
No full textSurgery was a painful and dangerous business at the start of the 19th century. There were no anesthetics so few operations were carried out. In surgical operations, pain would be intolerable if not controlled. Throughout history, there have been numerous attempts at controlling and eliminating pain. The Chinese developed acupuncture. The Greeks and Romans used alcohol to not only cleanse the body; they also encouraged the patient to drink the alcohol to the point of oblivion. To alleviation of the pain the stage of analgesia was achieved by the administration of Tikshna Madhya [Alcoholic preparation] only as Sushruta has advised. For overcome the overdose of the Alcohol preparation and other complications like blood loss, electrolyte imbalance etc. Sushruta had advised preoperative food administration. Basically Sushruta is the pioneer of surgery he taken care of all the aspects of surgery, one of them preoperative Alcohol, more or less anesthetic, administration is the important principle and is adequately mentioned. According to the study of its properties, absorption, metabolism, elimination and effect, alcohol is found to be a potent anesthetic of those days
HARATALA (AS2S3): AN IMPORTANT ARSENIC COMPOUND USED IN AYURVEDA
No full textAyurveda, the science of life is being practiced by Aryans from Vedic period. Arsenic compounds are popularly used in Ayurveda therapeutics since centuries. Haratala, Manahshila and Somala are important arsenic compounds used in Ayurveda. Haratala being important among them is commonly used in treating the diseases like Sleshmaroga, Raktapitta, Vatarakta, Kustha etc. Haratala is called orpiment of yellow arsenic with two molecules of Arsenic and three molecules of Sulphur (AS2S3). Haratala (Arsenic) is a poison which vary with the type and concentration of the poison. Haratala consumed without proper Shodhana shortens the life span, causes diseases of Kapha and Vata, Prameha, Santapa, Spotha, Snayu Sankocha. Hence Shodhana of Haratala is essential. Shodhana is the process of removal of physical, chemical impurities and potentiating of the drugs. Generally Shuddha Haratala is not given alone. It is administered along with herbal drugs or in the form of Rasamanikya or also as a main ingredient in most of the popular formulations like Samirapannaga Rasa, Vatagajankusha Rasa etc. There are different medias explained in literature for Shodhana of Haratala. According to the media of purification the quality and pharmacological properties of Haratala will vary. Depending on the change in properties the therapeutic effect may also vary. The present study includes the introduction of Haratala, origin of Haratala, types, properties, uses, Ashudha Haratala Guna, its management, modern review of Haratal and different Shodana Dravyas is explained
Study of pharmacological effect of ethanolic extract of Trikatu (EET) on learning and memory in rats.
No full textAbstract:
The current study was conducted to evaluate the effect of ethanolic extract of trikatu (EET) on learning and memory in rats. This effect was assessed using Elevated Plus maze, Y Maze and Novel Object Recognition. The phytochemical constituents present in ethanolic extract were also evaluated.
Three models each were used to ascertain the effects on learning and memory and two test groups, with a dose of 500mg/kg and 1000 mg/kg respectively were selected. Piracetam was used as a standard drug for learning and memory which was administered intraperitoneally. However, only the group showing more significant effect was subjected to the remaining two tests, in both cases.
The ethanolic extract, at doses of 500 mg/kg and 1000 mg/kg, was administered to rats by oral route. Piracetam was used as a standard for evaluation of learning and memory. The test doses were administered continuously for a period of seven days. The animals were subjected to the above mentioned tests and the observations were recorded at different time intervals on the first, fourth and seventh day. The results were statistically analyzed using one way ANOVA by Dunnett’s test.
From the results it was concluded that EET at both doses, 500mg/kg and 1000mg/kg were found to have significant learning and memory enhancing activity. Further in vitro analysis is required to understand exact mechanism of improved learning and memory.
Key words: learning, memory, trikatu.
 
A CASE STUDY TO EVALUATE THE EFFICACY OF SHATAVARI (ASPARAGUS RECEMOSUS LINN.) IN KRISHA MADHUMEHI (TYPE 2 DIABETES MELLITUS)
No full textDiabetes mellitus is a major problem now a days throughout the World. The incidence of the both types ofDiabetes are rising, it is estimated that in 2000, 171 million people had Diabetes and this is expected to doubleby 2030 by worldwide. It is explained in Ayurveda as Madhumeha. Acharya Charak described themanagement of Madhumeha considering the body constitution &strength of the patient. There are twotypes madhumehi, one is having stout body structure with good strength (sthula&valasali) & another is havinglean & thin body structure without strength (krisha&durbal). AcharyaCharakhas mentioned to give brimhan orsantarpan therapy in Krishamadhumehi. Shatavari (Asperagus racemosus) is such a drug whichhas brimhaneeya property as well as it is also found to be effective in the treatment and control of madhumeha.In the present study Shatavari (Asparagus recemosus Linn.) is selected for clinical trial to the patienthaving Madhumeha with Krishata. The assessment was done on the basis of subjective parameters andobjective parameters like BMI, blood sugar and urine sugar level of patient who was selected from OPD ofGaur Brahaman Ayurvedic College, Haryana. Shatavari moola churan was given at the dose of 6 gm twicedaily for consecutive 2 months. BMI,Fasting and PP blood sugar and urine sugar level were computed beforeand after treatment. Result showed marked improvement in sign and symptoms of the patient along withimprovement in BMI and lowering of blood and urine sugar level.After evaluating the total effect of therapiesit was revealed that Shatavari is very much beneficial to increase the body weight of the patient along withgood control of blood sugar level
UTILITY OF RASADRAVYAS IN PANCHAKARMA
No full textAyurveda is an ancient and traditional system of medicine dealing with various aspects of Ayu i.e life. The Astanga Ayurveda or the 8 important branches of the science emphasize the prevention of diseases and cure of existing ailments. Panchakarma is one of the part of Ayurveda which focuses on using five important therapies in curing the diseases. They include Vamana (emesis), Virechana (purgation), Basti(enema), Nasya (errhines) and Raktamokshana (bloodletting. Rasadravyas are drugs of mineral and metallic origin which are mainly dealt in another branch called Rasashastra which focuses on usage of such metals/minerals therapeutically. Though Panchakarma as well as Rasashastra are not included in Astanga Ayurveda, the utility of both the sciences are found in all the eight branches. The present article aims to establish the utility of drugs of metal/mineral origin in the field of Panchakarma
A CASE STUDY ON PAIN MANAGEMENT IN KADAR THROUGH AGNIKARMA
No full textThe description of Kadar is given in kshudra roga by Acharya Sushruta in Sushruta Samhita. Acharya Bhoj described it as Manskeel. According to Acharya Sushruta, Kadar has very simple pathology but is very difficult to cure. There is involvement of meda and rakta with dosha. Initially this disease is painless but later on it becomes very painful. In modern sciences it can be compared with corn. In modern surgery the only form of treatment of a corn that affords any reliable prospect of cure is excision. In this study corn is treated by Agnikarma using Ashtadhatu shalaka in a systematic manner for a duration of 12 days with intervals of 6 days in 3 sittings
PCOS; AN APPROACH TO ITS ETIO-PATHOGENESIS IN AYURVEDIC PARLANCE
No full textBackground: Polycystic ovarian syndrome is increasing in Gyanecological disease proportions globally. PCOS is a syndrome that includes clinical conditions involved oligo-anovulation, hyperandrogenism and polycystic ovarian morphology. Materials and methods: In this a critical review of Ayurvedic and Modern literature regarding the problem that is Polycystic ovarian syndrome was carried out. It covered all the relevant information from ancient classics to latest treatises which was searched, compiled & analyzed systematically. Results: PCOS is to be under stood on the basis of Dosha dushti, involvement of Dushya, Srotas, Ama, Agni, Adhistana and Vyadhi Lakshana. As it seems that whole metabolic process is disturbed in PCOS which is considered as dhatwagni vikar in ayurveda and no any diseases in classics indicate whole specturum of PCOS. So, we can say it “Dhatwagni mandya janya beejagranthi vikar.” Conclusion: Various dietary, lifestyle, and psychologic factors are involved in the etiology of PCOS, particularly in relation to metabolism. The ancient Ayurvedic knowledge can be utilized to expand the current understanding of pcos features like Menstrual irregularity, anovulation, hyperandrogesim, obesity, metabolic syndrome
LITERARY STUDY OF THE HOLISTIC HEALTH EFFECTS OF VIRECHANA KARMA IN EKA-KUSHTHA
No full textEka-kushtha (Psoriasis) is mainly vata kapha dominating disease. It not only affects the sharir (Body)but also affects the mana (Mind). Though modern medicine has solution but Ayurveda therapy notonly concern about the purification of the body but also focus on the well being of the mansik bhava(Psychological factors) its main aim is to maintain the swastha indriya, (Healthy sensory perception)swastha mana (Healthy Mind), as mansik hetu (Psychological Etiology) plays important role in thedisease Eka-kushtha (Psoriasis). Among the panchakarm, virechan karma (Purgative therapy) is selectedbecause it has a good result in the mana ( Mind) and sharir (Body) as it is given in the benefits ofthe virechan karm (Purgation Therapy) and also it is used for the treatment of vata and kapha.. So,here main Aim is to study the Holistic Health effects of virechan karm (Purgation Therapy) in Eka-Kushtha (Psoriasis). Objectives are to do literary study on the mansik bhavas (Psychological factors) byvalidated questionnaires in Eka-Kuhstha (Psoriasis) . Virechan (Purgation) is given by Abhyadimodak asthe ingredients like trivrut, amalaki, pippali danti etc. have vata-kapha alleviating properties. On thebasis of mentioned discussion it is concluded that Eka-kushtha (Psoriasis) could be treated throughvirechan (Purgation)