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RNA-seq data analysis : a practical approach / Eija Korpelainen, Jarno Tuimala, Panu Somervuo, Mikael Huss, Garry Wong.
No full text"A Chapman & Hall book."pharmacy bookfair2015Includes bibliographical references and index.xxiv, 298 pages :"RNA-seq offers unprecedented information about transcriptome, but harnessing this information with bioinformatics tools is typically a bottleneck. This self-contained guide enables researchers to examine differential expression at gene, exon, and transcript level and to discover novel genes, transcripts, and whole transcriptomes. Each chapter starts with theoretical background, followed by descriptions of relevant analysis tools. The book also provides examples using command line tools and the R statistical environment. For non-programming scientists, the same examples are covered using open source software with a graphical user interface"-- Provided by publisher
STRAIN INDUCED WITHIN ANTERIOR ZIRCONIA CANTILEVER BRIDGES WITH DIFFERENT RETAINER DESIGNS
No full textStatement of problem. Zirconia cantilever bridge may be a restorative treatment alternative for the replacement of missing maxillary lateral incisor. Different preparation designs have been recommended, but still the effect of these preparation designs on the amount and location of strain induced within these restorations need to be investigated.
.Purpose. The purpose of this study was to investigate the strain induced within zirconia all ceramic cantilever anterior bridges as influenced by the effect of retainer designs and direction of loading.
Material and methods. A total of 60 all-ceramic zirconia cantilever bridges were constructed and divided according to retainer design into three main groups (n=20), Group I: Full coverage retainer, Group II: Three-Quarter retainer, Group III: Three-Quarter retainer with labial extension. Each group was further subdivided according to the direction of loading into two subgroups (n=10). Subgroup (V): Vertical loading (Parallel to tooth long axis), Subgroup (L): Lateral loading (45 degree from tooth long axis). Two KYOWA strain gauges were bonded, one at the lingual surface of the connector and the other at the cervical third of the distal surface of the bridge retainer using strain gauge cement. The samples were subjected to vertical and lateral loading (150 N) using universal testing machine. The strain induced in the samples was measured by a KYOWA strain meter
Reliability of linear and angular dental measurements with the OrthoMechanics Sequential Analyzer
No full textThe aim of this study was to evaluate the reliability of newly developed software in the assessment of orthodontic tooth movement 3 dimensionally. Methods: The sample consisted of pretreatment and posttreat- ment computed tomography scans and plaster dental models of 20 orthodontic patients treated with a hyrax palatal expander as a part of their comprehensive orthodontic treatment. Dental-arch measurements, including arch widths, tooth inclinations, and angulation parameters, were measured on the scans using InvivoDental 3D imaging software (version 5.1; Motionview, Hixson, Tenn). The plaster dental models were laser scanned and superimposed, and measurements were obtained digitally using the new software. Agreement between the digital models and the computed tomography measurements was evaluated with intraclass correlation coefficients, paired t tests, and Bland-Altman plots. A P value of #0.05 was considered statistically significant. Results: High agreement, a nonsignificant paired t test, and no indication of agreement discrepancies were observed for most of the measured parameters. Conclusions: The results confirmed that the new software program offers a reliable tool for dental-arch measurements obtained from 3-dimensional laser-scanned models
Dental anatomy, physiology, and occlusion
No full textdental bookfair2016Includes bibliographical references and index.x, 350 pages :Now in full color, this essential text features a visually oriented presentation of dental anatomy, physiology, and occlusion ― the foundation for all of the dental sciences. Coverage includes discussions of clinical considerations, dentitions, pulp formation, and the sequence of eruptions. In addition to detailed content on dental macromorphology and evidence-based chronologies of the human dentitions, this edition also includes flash cards, an updated Companion CD-ROM, and Evolve resources that make this text a comprehensive resource for dental anatomy.
• Understand the standards of tooth formation and apply them to clinical presentations with the Development and Eruption of the Teeth chapter.
• Focus on the functions and esthetics of disorders you’ll encounter in daily practice with content on TMJ and muscle disorders.
• Get a concise review of dentition development from in-utero to adolescence to adulthood with the appendix of tooth morphology.
• All line drawings and essential photos have been replaced with full-color pieces.
• Sharpen your knowledge with interactive learning tools and expanded content on the Companion CD-ROM including study questions, 360-degree rotational tooth viewing, and animations.
• Test your knowledge on labeling, tooth numbering, and tooth type traits and prepare for Board exams with flash cards.
• Find even more study opportunities on the Evolve website with a PowerPoint presentation, flash cards, a test bank, and labeling exercises
Design, Optimization, and Validation of Thin-Layer Chromatography– Densitometry and Chemometry-Assisted Spectrophotometry: A Comparative Study Applied on Quaternary Mixture
No full textThis work presents a comparative study on the development and validation of two analytical techniques applied for the simultaneous determination of hydrocortisone acetate (HCA), fusidic acid (FSA), methyl paraben (MPB), and propyl paraben (PPB) formulated as a topical cream. The first technique was thin-layer chromatography (TLC)-densitometric method, which was developed by separating the four components on silica gel 60 F254 using methylene chloride-methanol-benzene in the ratio of 10:2:5, v/v, as the developing system, followed by densitometric measurement of the bands at 240 nm. The second technique was the chemometric method using two models: principle component regression model (PCR) and partial least squares (PLS). The suggested techniques were validated in compliance with the International Conference on Harmonization (ICH) guidelines and were successfully applied for the determination of the quaternary mixtures as prepared synthetically in laboratory and in the commercial topical pharmaceutical formulation.
(PDF) Design, Optimization, and Validation of Thin-Layer Chromatography–Densitometry and Chemometry-Assisted Spectrophotometry: A Comparative Study Applied on Quaternary Mixture. Available from: https://www.researchgate.net/publication/284172660_Design_Optimization_and_Validation_of_Thin-Layer_Chromatography-Densitometry_and_Chemometry-Assisted_Spectrophotometry_A_Comparative_Study_Applied_on_Quaternary_Mixture [accessed Nov 22 2018]
EFFECT OF LOW THERMAL DEGRADATION AND VENEERING TECHNIQUES ON COLOR AND TRANSLUCENCY OF ZIRCONIA RESTORATIONS
No full textPurpose: This study evaluated the effect of veneering techniques and aging on the color reproduction, stability and translucency of zirconia (Y-TZP) all-ceramic restorations. Materials and Methods: Thirty all ceramic crowns were constructed and divided according to their veneering technique into three groups (n = 10/group).Group 1: Translucent Zirconia milled by (fully anatomical technique), Group 2: Zirconia coping was veneered by condensing and sintering VM9 low-fusing veneering porcelain (layering technique), Group 3: Zirconia coping was veneered by heat-pressing IPS e.max ZirPress fluorapatite glass-ceramic ingots (press-on technique). Low thermal degradation (LTD) using autoclaving for 8 hours was performed. Color parameters (L*, a*, b*) of zirconia crowns were measured with Vita Easyshade Compact (VITA, Zahnfabrich H. Rauter GmbH and Co. KG). Color reproduction, color stability, contrast ratio and translucency parameter were calculated before and after aging. Two-way analysis of variance (ANOVA), followed by Tukey’s post hoc test at a significance level of p≤0.05 was performed
Molecular, cellular, and tissue engineering / edited by Joseph D. Bronzino and Donald R. Peterson.
No full textIncludes bibliographical references and index.various page .:Known as the bible of biomedical engineering, The Biomedical Engineering Handbook, Fourth Edition, sets the standard against which all other references of this nature are measured. As such, it has served as a major resource for both skilled professionals and novices to biomedical engineering.
Molecular, Cellular, and Tissue Engineering, the fourth volume of the handbook, presents material from respected scientists with diverse backgrounds in molecular biology, transport phenomena, physiological modeling, tissue engineering, stem cells, drug delivery systems, artificial organs, and personalized medicine.
More than three dozen specific topics are examined, including DNA vaccines, biomimetic systems, cardiovascular dynamics, biomaterial scaffolds, cell mechanobiology, synthetic biomaterials, pluripotent stem cells, hematopoietic stem cells, mesenchymal stem cells, nanobiomaterials for tissue engineering, biomedical imaging of engineered tissues, gene therapy, noninvasive targeted protein and peptide drug delivery, cardiac valve prostheses, blood substitutes, artificial skin, molecular diagnostics in personalized medicine, and bioethics
Metagenomics for microbiology / edited by Jacques Izard, Maria C. Rivera.
No full textIncludes bibliographical references and index.xii, 175 pages ;Concisely discussing the application of high throughput analysis to move forward our understanding of microbial principles, Metagenomics for Microbiology provides a solid base for the design and analysis of omics studies for the characterization of microbial consortia. The intended audience includes clinical and environmental microbiologists, molecular biologists, infectious disease experts, statisticians, biostatisticians, and public health scientists. This book focuses on the technological underpinnings of metagenomic approaches and their conceptual and practical applications.
With the next-generation genomic sequencing revolution increasingly permitting researchers to decipher the coding information of the microbes living with us, we now have a unique capacity to compare multiple sites within individuals and at higher resolution and greater throughput than hitherto possible. The recent articulation of this paradigm points to unique possibilities for investigation of our dynamic relationship with these cellular communities, and excitingly the probing of their therapeutic potential in disease prevention or treatment of the future
Python projects / Laura Cassell, Alan Gauld.
No full text"Wrox programmer to programmer"--Cover.computer bookfair2016Includes bibliographical references (pages 327-331) and index.xxx, 350 p. :Provides information on real-world Python programming, including a review of Python data types, using control structures, managing data, creating modules and packages, and debugging code
Information security analytics : finding security insights, patterns, and anomalies in big data / Mark Ryan M. Talabis, Robert McPherson, I. Miyamoto, Jason L. Martin ; D. Kaye, technical editor.
No full textcomputer bookfair2016Includes bibliographical references and index.xv, 166 pages :Information Security Analytics gives you insights into the practice of analytics and more importantly analytic techniques to identify trends and outliers, which may not be possible using traditional security analysis techniques. Information Security Analytics dispels the myth that analytics within the information security domain is limited to just security incident and event management systems and basic network analysis. Analytic techniques can help you to mine data and to identify patterns and relationships in security data. Using the techniques covered in this book, you will be able to gain security insight into unstructured data of any type. The authors of Information Security Analytics bring a wealth of analytics experience to demonstrate practical, hands-on techniques using case studies. They demonstrate how you can use freely available tools to find anomalies and outliers by combining disparate data sets. They also teach you everything you need to know about threat simulation techniques and how to use analytics as a powerful decision-making tool to assess security control and process requirements within your organization. Ultimately, you will learn how to use these simulation techniques to help predict and profile potential risks in your organization. Written by security practitioners, for security practitioners, Learn about open-source analytics and statistical packages, tools and applications, Real-world case studies and scenarios are provided for each analytics technique, Step-by-step guidance on how to use analytics tools and how they map to the techniques and scenarios provided, Learn how to design and utilize simulations for "what-if" scenarios to simulate security events and processes, Learn how to utilize big data techniques to assist in incident response and intrusion analysis Book jacket