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Hepatoprotection and Antioxidant Activity of Gazania Longiscapa and G. Rigens with the Isolation and Quantitative Analysis of Bioactive Metabolites
No full textGazania longiscapa and G. rigens are two species belonging to family Asteraceae. The present study aimed the isolation
of the main active constituents from the methanol extracts using different chromatographic methods and their identification
using different spectroscopic techniques, beside the quantitation of some biologically important active constituent as rutin
using HPLC technique, together with estimation of total polyphenolic content calculated as gallic acid and estimation of
total flavonoid content calculated as rutin using UV technique. Concomitantly the determination of the antioxidant and
hepatoprotective activity of the total methanol extracts of the aerial parts of G. longiscapa and G. rigens. This work resulted
in the isolation of 4 flavonoids (Apigenin, Luteolin, Luteolin 7-O-β-D-glucopyranosid, Apigenin 7-O-β-Dglucopyranosid),
3 phenolic acids (Caffeic acid, Chlorogenic acid and 3,5- di- O-caffeoylquinic acid) from G. longiscapa
for the first time; these 3 phenolic acids were also isolated from G. rigens, together with one flavonoid (rutin), The
quantitative determination of the methanol extracts showed that G. longiscapa is a richer source of phenolic acids than G.
rigens and both Gazania species are valuable sources of rutin beside having hepatoprotective and antioxidant activity
Future Dental Journal Volume 2, Issue 2
No full textArticles : Zirconia based ceramics, some clinical and biological aspects: Review -- Effect of accelerated aging on translucency of monolithic zirconia -- Patient satisfaction of tooth supported overdentures utilizing ball attachments -- Crestal bone loss of standard implant versus platform switch implant design using minimal invasive technique -- Temporomandibular joint chronic closed lock: Spontaneous resolution following surgical arthroscopy -- Clinical assessment of intra-articular fentanyl injection following arthrocentesis for management of temporomandibular joint internal derangement -- Adenoid variant of peripheral ameloblastoma with cellular atypia in the retromolar pad area: A case report -- Sjögren's syndrome in a 25-year-old female: A case study -- Palatal caliber persistent artery in a diabetic patient -- Intraparotid facial nerve schwannoma: A case reportFuture Dental Journal (FDJ) publishes scientific articles, case reports and comparison studies evaluating materials and methods of dental treatment and also articles concerned with dental education.
Dentists can learn about new concepts, clinical developments, clinical opinions, treatments and the latest advances in techniques and instrumentation that helps them keep pace with rapid changes in this field and provide them with a knowledge transfer platform for rapid publication of reports and articles through an international journal.
This journal encourages researches concerning improvement of dental health through the latest technologies as tissue engineering, nanotechnology, laser application and implantology.
The journal is interested in inter- disciplinary articles within the dental field, and group work with other disciplines as medicine, physics and chemistry. The journal also aims to provide clinicians, scientists and students of dentistry with a knowledge transfer platform for rapid publication of reports and articles through an international journal.Subject areas include, but are not limited to the following fields: •
Periodontics
Orthodontics
Endodontics
Oral medicine
Dental Radiology
Oral surgery
Dental materials
Oral sciences
Pedodontics
Oral biology
Prosthodontics
Dental implants
Crown and Bridge
Oral Pathology and Microbiology
Community dental health
Oral hygiene
Cosmetic dentistry
Dental educationFuture University In Egyp
Nameless Field (bahariya formation) Western Desert of egypt
No full textTarget:Apply the ideal ways to evaluate and development of a field area BAH formation And ideal way to design a well in order to achieve all of the required technical data during by meaning of minimizing reservoir impairments and damaging. Given Data:* Regarding offset Data
Requirements:*Volumetric Estimation *Formation Evaluation *Drilling Prognosis *Tubing Size Selection *Suitable Artificial Lift SystemThis field is faulted anticline structure located in the Western Desert. The field produces from different layers mainly shaly sand and sand with different thickness. The main producing formation is Baharyia which will present the main target formation. This report is talking about evaluation and development of an x-field area on Baharyia formation western desert in Egypt with several drilled wells, The development will occur according to the study of geology and the volumetric estimate, offset data of drilled well in the field to design a well in order to achieve all of the required technical data during and post drilling operations as well as been reservoir friendly by meaning of minimizing reservoir impairments and damaging , formation evaluation, reservoir engineering, and production engineering. The study and the evaluation on the x-field will give a view of next step of reserve calculation and development plans to start water flooding development based on the interpretation of the given items
Phenotypic and genotypic characterization of Pseudomonas aeruginosa isolates from Egyptian hospitals
No full textseudomonas aeruginosa (P. aeruginosa) is an opportunistic pathogen and a leading cause of hospital-
acquired infections. Characterization of the isolates from different infection sites might help to control
infections caused by the pathogen. The aim of the present work is to characterize P. aeruginosa
isolates recovered from different clinical specimens at two hospitals in Cairo with regard to their
antibiogram, genotypes and virulence factors. The highest antimicrobial resistance pattern was
exhibited by isolates from sputum. Resistance rate recorded for sputum samples to different in- use
antibiotics was 80, 80-100, 36, 54 and 54% for Penicillins, Cephems, Carbapenems, Aminoglycosides
and Fluoroquinolones, respectively. Phenotypic detection of virulence factors in P. aeruginosa isolates
included detection of protease, lecithinase, DNase, hemolysin and pyocyanin revealed that, each isolate
had at least one virulence factor. Protease and lecithinase were the most commonly detected, where 68
and 66% of the isolates showed positive protease and lecithinase activities respectively. Random
amplified polymorphic DNA (RAPD) genotyping using 2 random primers revealed 22 and 14 different
genetic profiles. Phylogenetic trees based on genetic distances showed 3 clusters with obvious
similarity between some isolates, indicating common sources of infection. No association could be
found between clustering pattern of the isolates, their antibiogram and virulence
A Cloud Interoperability Broker (CIB) for Data Migration in SaaS
No full textsolutions. However, there is isolation in the cloud implementations provided by the cloud vendors. Limited interoperability can cause one user to adhere to a single cloud provider; thus, a required migration of an application or data from one cloud provider to another may necessitate a significant effort and/or full-cycle redevelopment to fit the new provider's standards and implementation. The ability to move from one cloud vendor to another would be a step toward advancing cloud computing interoperability and increasing customer trust. This study proposes a cloud broker solution to fill the interoperability gap between different software-as-a service providers. The proposed cloud broker was implemented and tested on a real enterprise application dataset. The migration process was completed and it worked correctly, according to a specified mapping model
Development and Validation of Stability Indicating Spectrophotometric Methods for Determination of Sulbutiamine in Tablet Dosage Form
No full textFive sensitive, selective and precise stability-indicating spectrophotometric methods for the
determination of Sulbutiamine (SUL) in the presence of its alkali-induced degradation product (DEG) were
developed and validated. Method A is differential dual wavelength (D1
DWL) applied in the analysis of SUL in
binary mixture via its first derivative spectra using the difference between two points with equal amplitudes in
the alkali-induced degradation product, thus DEG acts as zero contribution. Method B is second derivative
spectrophotometry (D2
), which allowed the determination of SUL at 300.0 nm. Method C is second derivative
of the ratio spectra (DD2
) in which SUL was determined by measuring the peak amplitude at 301.0 nm.
Method D is the ratio difference spectrophotometry (RD), where the difference between amplitudes of the
absorbance ratio spectra at 237.2 and 274.0 nm were recorded and Method E; Ratio subtraction (RSM) where
the zero order spectra of pure SUL were extracted from their laboratory prepared mixtures, and consequently
SUL can be analyzed at its maxima. The linearity for SUL was obtained within concentrations ranging from
5.00 - 50.00 μg/mL with percentage recovery of 100.58 + 0.98, 99.62 ± 1.16, 100.70 ± 1.38, 100.06 + 1.00
and 99.56 + 1.00 for the five methods, respectivel
Egypt’s north sinai post 2011 revolution: the nexus between ungovernability dimensions and terrorism
No full textUnlike other Egypt’s provinces, terrorism in the Egypt’s North Sinai seems as sustained terror with a wide base of extremist militant groups. The main objective of this study is to answer the question of “why has terrorism escalated dramatically in Egypt’s North Sinai province post 2011 and 2013?” After analyzing the literature on different causal explanation of terrorism, it is found a shortage in terms of analyzing the nexus of ungovernability and terrorism. Therefore, this study uses different concepts of ungovernability dimensions, relative deprivation theory, and state repression concept to analyze them in relation to terrorism escalation in the case study of Egypt’s North Sinai. The methodology of this study depends on qualitative tools of analysis as well as statistical methods to analyze the terrorism phenomena in North Sinai. Essentially, this study used empirical research methods through conducting twenty in-depth interviews with various samples. Through analyzing this case study, it is found that the ungovernability increases the opportunity of terror, especially in the case of selective state penetration. For the sake of enriching the literature, this study provides an analytical explanatory framework of the nexus between ungovernability dimensions and terrorism. Finally, this study proposes four policy recommendations to reinforce the level of governability in North Sinai province
UPLC–MS-MS Method for the Determination of Vilazodone in Human Plasma: Application to a Pharmacokinetic Study
No full textA sensitive, rapid and simple liquid chromatographic-electrospray ionization tandem mass spectrometric (LC-ESI-MS-MS) method was developed for the quantitative determination of vilazodone in human plasma and for the study of the pharmacokinetic behavior of vilazodone in healthy Egyptian volunteers. With escitalopram as internal standard (IS), liquid-liquid extraction was used for the purification and preconcentration of analytes from human plasma matrix using diethyl ether. The separation was performed on an Acquity UPLC BEH shield RP C18 column (1.7 µm, 2.1 × 150 mm). Isocratic elution was applied using methanol-0.2% formic acid (90:10, v/v). Detection was performed on a triple-quadrupole tandem mass spectrometer with multiple reaction monitoring mode via an electrospray ionization source at m/z 442.21 → 155.23 for vilazodone and m/z 325.14 → 109.2 for escitalopram. Linear calibration curves were obtained over the range of 1-200 ng/mL with the lower limit of quantification at 1 ng/mL. The intra- and inter-day precision showed relative standard deviation ≤3.3%. The total run time was 1.5 min. This method was successfully applied for clinical pharmacokinetic investigation, and a preliminary metabolic study was also carried out
Nano Spray Drying Technique as a Novel Approach To Formulate Stable Econazole Nitrate Nanosuspension Formulations for Ocular Use
No full textThe effect of using methyl-β-cyclodextrin and hydroxypropyl-β-cyclodextrin as carriers for econazole nitrate nanoparticles prepared by nano spray dryer was explored in this work. Stabilizers, namely, poly(ethylene oxide), polyvinylpyrrolidone k30, poloxamer 407, Tween 80, and Cremophor EL, were used. The nano spray dried formulations revealed almost spherical particles with an average particle size values ranging from 121 to 1565 nm and zeta potential values ranging from −0.8 to −2.5 mV. The yield values for the obtained formulations reached 80%. The presence of the drug in the amorphous state within the nanosuspension matrix system significantly improved drug release compared to that for pure drug. Combination of hydroxypropyl-β-cyclodextrin with Tween 80 achieved an important role for preserving the econazole nanosuspension from aggregation during storage for one year at room temperature as well as improving drug release from the nanosuspension. This selected formulation was suspended in chitosan HCl to increase drug release and bioavailability. The in vivo evaluation on albino rabbit’s eyes demonstrated distinctly superior bioavailability of the selected formulation suspended in chitosan compared to its counterpart formulation suspended in buffer and crude drug suspension due to its mucoadhesive properties and nanosize. The nano spray dryer could serve as a one step technique toward formulating stable and effective nanosuspensions
A Complete Study on Nameless field Bahryia formation
No full textTarget : Apply the ideal ways to evaluate and development of a field BAH formation and ideal way to design a well in order to achieve all of the required technical data during by meaning of minimizing reservoir impairments and damaging * Given Data: Regarding offset Data * Requirements:* Volumetric Estimation *Formation Evaluation *Drilling Prognosis *Tubing Size Selection *Suitable Artificial Lift SystemPetroleum Engineering is an engineering discipline concerned with the activities related to the production of hydrocarbons, which can be either crude oil, or natural gas. Exploration, production, refinement, and distribution to a market are the industries related to this highly technical engineering profession. Petroleum Engineering requires a good knowledge of many other related disciplines, such as geophysics, petroleum geology, formation evaluation (well logging), drilling, economics, reservoir simulation, well engineering, artificial lift systems, and oil and gas facilities engineering.
This report is talking about evaluation and development of a nameless field on Baharyia formation western desert in Egypt with several drilled wells, The development will occur according to the study of geology and the volumetric estimate, offset data of drilled well in the field, formation evaluation, reservoir engineering, and production engineering. The study and the evaluation on the x-field will give a view of next step of reserve calculation and development plans to start water flooding development based on the interpretation of the given items