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RECENT DEVELOPMENT IN ULTRAVIOLET SPECTROPHOTOMETRY THROUGH THE LAST DECADE (2006–2016): A REVIEW
No full textVol 8, Issue 10Several techniques have been proposed for treatment of spectrophotometric data, with the objective of extracting the largest amount of analytical
information from spectra composed of unresolved bands. The instrumental development and analytical applications of UV regions absorption
spectrophotometry produced in the last 10 y (since 2006) are reviewed. The methods were classified according to the spectra data used, including
zero order absorption, derivative and ratio amplitudes. The proposed methods wer
THE EFFECT OF DIFFERENT FLAP TECHNIQUES ON BONE CHANGES IN SPLIT CREST RIDGES WITH SIMULTANEOUS IMPLANT PLACEMENT.
No full textStatement of problem:-The maxillary ridge split treatment options, which include different flap techniques with simultaneous implant placement, may help eliminate the current undetermined best choice of treatment plan. Purpose: - The aim of this systematic review was to evaluate outcome of simultaneous implants placement in alveolar ridge split carried out by different flap approaches on marginal bone changes and survival rate. Materials and Methods: - English publications on the subject were searched to select articles up to December 2015. Articles in peer- reviewed journals were searched in an electronic database (MEDLINE, Pub- Med and Cochran). Also, a manual search studies on humans was carried out. Two independent reviewers screened 855 papers. Result: - 843 articles were excluded on the basis of the title and abstract. Full-text articles were obtained for the 12 selected publications. The 12 full texts were assessed by the two reviewers and 3studies were found fitting for inclusion. Conclusion: - The limited data indicates that the flap design does not affect bone changes and survival rate in ridge split procedure with simultaneous implant placement
Elswedy for cement (second production line)
No full textConstructing the second production line of Elsweedy company for Cemen
Development and optimization of self-assembling nanosystem for intra-articular delivery of indomethacin
No full textOsteoarthritis is a propagated debilitating condition affecting patients' quality of
life. Intra-articular injection approach was investigated as a localized treatment
strategy providing: site-specific delivery, decreased side effects and, increased
patient compliance. A 32
full factorial experimental design was employed to
prepare the indomethacin-loaded self-assembling nanosystems (SANS). The
surfactant (Poloxamer 407/Tetronic 90R4) ratio and the poly(lactic-co-glycolic acid) (PLGA) concentration significantly affected encapsulation efficiency and
drug release (p<0.05). The optimized formula was subjected to modification by
addition of different proteoglycans, as a compensatory treatment, to improve its
pharmacological properties. The modified SANS, containing glucosamine (150
mg), was selected for in-vivo studies as it had a sustained drug release profile and a
small particle size (173.90 nm). The effect of the optimized SANS, with or without
PLGA, was compared with the modified formula containing glucosamine and, with
the drug suspension on the arthritic knee joints of rats. It was found that the
formulation containing PLGA and glucosamine showed significantly higher
reduction in both, knee diameter and TNF-α levels, compared to other groups.
Furthermore, all SANS showed histological improvement in the cellularity of the
synovial membranes and joints. Our results indicate that SANS containing PLGA
and glucosamine is capable of treating arthritic joints
Remote Patient Monitoring
No full text• Every hospital needs an online system whereby it can accommodate the patients comfortably and avoid any confusion to the doctors regarding their work. There should be a system where the patients are categorized under insurance policy and non-policy holders and the system helps the hospital management to claim the bills from concerned insurance companies. All these needs and much more are fulfille
A Proposed Approach for Emotion Lexicon Enrichment
No full textDocument analysis is an important research field that aims to gather the information by analyzing the data in documents. As one of the important targets for many fields is to understand what people actually want, sentimental analysis field has been one of the vital fields that are tightly related to the document analysis. This research focuses on analyzing text documents to classify each document according to its opinion. The aim of this research is to detect the emotions from text documents based on enriching the lexicon with adapting their content based on semantic patterns extraction. The proposed approach has been presented, and different experiments are applied by different perspectives to reveal the positive impact of the proposed approach on the classification results
Synthesis, biological evaluation and molecular modeling study of thiadiazolo[3,2-a][1,3]diazepine analogues of HIE-124 as a new class of short acting hypnotics*
No full textA new series of 6,7-dihydro-[1,3,4]thiadiazolo[3,2-a][1,3]diazepine analogues were synthesized, and
biological evaluated. Compound GS-62 (33) exhibited potent in vivo short acting hypnotic activity with
onset time, duration of sleep and therapeutic index of 6.4 ± 0.2, 94.8 ± 5.3 min, 6.62, respectively), in
comparison to thiopental sodium (6). Compounds 33 did not show any sign of acute tolerance reported
with the maintenance dose of 6. Meanwhile 33 potentiated the in vivo hypnotic effect of 6 in an equimolar
amounts (0.06 mmol) combination showing an onset and duration of 7.5 ± 1.3, 62.5 ± 5.9 min,
respectively. This combination allowed the use of lower doses of both drugs to avoid the undesirable side
effects. Docking studies revealed favorable interactions and binding to BDZ binding site of the GABAA
receptor especially with Arg87, Arg149, and Thr151 amino acid residues
Future Journal of Pharmaceutical Sciences
No full textFuture Journal of Pharmaceutical Sciences issued under the auspicious of Future University in Egypt. The Journal publishes communications, original research articles, review articles and case studies on all aspects of the pharmaceutical sciences and related clinical subjects that are of interest to all health professionals with strong emphasis on originality and scientific quality. Specifically, the journal publishes original researches in all fields that interest Pharmacists as drug absorption & metabolism, pharmacokinetics & dynamics, drug delivery including gene delivery, drug targeting and nano-technology, Pharmacotherapeutics, community and hospital pharmacy as well as Pharmaceutical and hospital management. The scope will also cover researches in toxicology, cell and molecular biology, biomedical research, basic & clinical and pharmaceutical microbiology, Pharmaceutical biotechnology, medicinal chemistry, Phytochemistry and nutraceuticals.Proceedings of scientific meetings may be published as special issues or supplements to the Journal. Manuscripts submitted to the Journal are only accepted on the understanding that: they are subject to editorial review (generally by two independent referees); they have not been, and will not be, published in whole or in part in any other journal
An empirical study for integrating XP with VTSP to improve business process
No full textActual problems that threaten organizations are the excessive unnecessary organizational processes. The Business Process Reengineering (BPR) methodology is developed to improve the return of investment rates within organization. BPR guides to rearranging processes and removing unnecessary ones and consolidating the remaining processes into linear open syste
Development and validation of sensitive and rapid UPLC–MS/MS method for quantitative determination of daclatasvir in human plasma: Application to a bioequivalence study
No full textA rapid and sensitive UPLC–MS/MS method was developed and validated for determination of daclatasvir (DAC) in human plasma using sofosbuvir (SOF) as an internal standard (IS). The Xevo TQD LC–MS/MS was operated under the multiple-reaction monitoring mode using electrospray ionization. Precipitation with acetonitrile was used in sample preparation. The prepared samples were chromatographed on Acquity UPLC HSS C18 (50 × 2.1 mm, 1.8 μm) column by pumping 10 mM ammonium formate (pH 3.5) and acetonitrile in an isocratic mode at a flow rate of 0.30 ml/min. Method validation was performed as per the FDA guidelines and the standard curves were found to be linear in the range of 5–4000 ng/ml for DAC. The intra-day and inter-day precision and accuracy results were within the acceptable limits. A very short run time of 1.2 min made it possible to analyze more than 500 human plasma samples per day. The wider range of quantification of DAC allowed the applicability of the developed method for its determination in a bioequivalence study in human volunteers