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Prosthesis Repurposed in Flannery O’Connor’s “Good Country People” and “The Lame Shall Enter First”
No full textLab in Chemical Structure and Reactivity
No full textAn introduction to the methods of research in chemistry. Inorganic, organic, physical chemistry, computational chemistry, and biochemical concepts are integrated in a broad laboratory study of structure and its relationship to chemical reactivity. Physical methods are used in studies of organic, inorganic, and biochemical reactions. Chemical synthesis and the modern methods of computation and instrumental analytical chemistry are particularly stressed
Evaluating Health Expenditure Effectiveness: Does Political Structure Play a Role?
No full textImproving health outcomes is a top priority for governments across the world. This thesis evaluates the question what effects do health expenditures, public versus private, have on the health outcome of a country’s population? Additionally, does a country’s political structure have an effect on health outcomes? A comprehensive measure of health outcomes, the Disability-Adjusted Life Year (DALY), is used to assess the importance of different types of health expenditures on health outcomes. Effects vary by country income groups. Higher health expenditures are negatively correlated with health outcomes in high-income countries, while positively affecting health outcomes in lower middle and low-income countries. In particular, government expenditures in preventative health care are the most effective forms of health expenditures for lower middle and low-income countries. Higher levels of democracy are correlated with better health outcomes in upper middle-income countries. Policy implications include more resources devoted to government health spending in lower middle and low-income countries, while measures to improve effectiveness of health expenditures in high-income countries may be needed
Differential Equations
No full textThe study of differential equations can be conducted quantitatively, by studying various methods for finding explicit solutions, or qualitatively, by determining whether solutions exist and discussing their asymptotic behavior. We will take both approaches, beginning by finding solutions to single differential equations of first and second order, and then continuing to systems of differential equations. We will study the fundamental existence and uniqueness theorem for systems of differential equations, linearization, and theorems concerning periodic orbits. Throughout we will emphasize the connection of differential equations to physics; in a very real sense the study of differential equations is the study of physical reality.\ud
You will be called upon to apply the skills you learned in calculus and linear algebra to succeed in this course. Both computation and proof-writing will be required; you will practice reasoning\ud
and communicating in a mathematical fashion
The Determinants of Forced Manager Turnovers in Major League Soccer
No full textThis study seeks to identify the determinants of forced manager turnovers in Major League Soccer (MLS), specifically exploring the impact of the relationship between short and long-term performance, the variation from expected performance, and the relationship between various factors and forced turnovers over time. The data is comprised of over three thousand MLS fixtures played between 2004 and 2015. Using three different empirical models, this study finds no significant impact of past performance on the probability of being fired
The Effect of the UEFA Champions League Financial Payout System on Competitive Balance in European Soccer Leagues
No full textThe paper examines the effect of UEFA Champions League payouts on competitive balance across European leagues. A league-level specification identifies the magnitude of the effect of the UEFA payouts on three measures of competitive balance. The results confirm that the UEFA payouts have a statistically significant effect at the league-level depending on which competitive balance measure and league sample is used. However, the UEFA payouts had no statistically significant effect on individual clubs’ average annual payroll or the clubs’ qualification for the Champions League in the following season
Introduction to Literary Analysis
No full textFrom the humbling of Creon in Sophocles’ Antigone to the fall of Hester in Suzan-Lori Parks' In The Blood, this course examines the literature of transformation. Working with classical and modern texts in a variety of literary genres, this course will ask: How do characters transform in the face of desire, longing, violence, trauma, and loss? How do social structures transform (or fail to transform) through individual and collective action? We will look closely at contemporary adaptations of classical works, asking how the meanings of these works are transformed over time and across various media—including film, theater, dance, and performance art. Finally, we will also track our own transformations over the course of the semester, asking how the practice of reading and writing literature and criticism transforms our senses of self and other. Particular attention will be paid to the politics of identity in the work of transformation, including gender, sexuality, race, and class
Ecological Imaginaries
No full textThis course interrogates how representations and imaginings of the environment are inseparable from issues of social justice. It will turn to those people arguably most severely affected by global climate change: the poor whose jobs are often based on weather, who are usually hit the worst by “natural” disasters such as hurricanes, and who are almost always displaced by the forces of global capital flows. Considering how literature, film, and art imagine and engage the environment in an effort to address questions of social equality, cultural and geographical displacement, and human rights, we will explore and investigate a range of topics that arise from the intersection of racism, sexism, imperialism, globalization, and the environment. We will \ud
examine issues such as the idea of “wilderness”; environmental racism; the politics of water; the anthropocene; poetry, ecology, and cultural belonging; eco-poetics; queer ecologies; globalization and border ecologies; food justice; neocolonialism and tourism; ecomedia; and environmental art.\ud
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This seminar carries credit toward the concentrations in Environmental Studies and Gender and Sexuality Studies, and it corresponds with an artist residency for Iñupiaq American poet and interdisciplinary cultural worker Joan Naviyuk Kane, which is sponsored by the Hurford Center for the Arts and Humanities at Haverford College
Genetic and Structural Characterization of Novel Decision-Making Genes in Zebrafish
No full textDecision-making is a crucial element of life for many organisms, but its genetic and neural basis is not very well understood. Many studies have focused on elucidating the genes and neural pathways behind decision-making, with zebrafish becoming an increasingly popular model organism to use for this research. Zebrafish are a vertebrate model and have many genetic and physiological similarities to humans, but they also reproduce quickly and in large numbers, making them a good model organism for large-scale genetic screens. The acoustic startle response is a well-characterized zebrafish behavior, and previous genetic screens isolated mutants with decision-making defects related to this behavior. I attempted to find the causative mutations for the decision-making mutants procrastinator and fashionably late. I was not able to find any genes or chromosome regions that looked linked to the mutations, but the process I used should continue to be utilized in future experiments. I also examined the brain structure and circuitry of ignorance is bliss fish, another strain of decision-making mutants, to try to determine if differences in neuronal structure could help influence behavior. I compared the brains of mutant fish to those of their wild-type siblings, and found that the ventral dendrites in mutants appear to be structurally different compared to the siblings. These differences may inform how the mutant phenotype comes about
Characterization of Distribution of Aggregation States of ⍺-Synuclein in Drosophila melanogaster
No full textParkinson’s disease (PD) is the most common neurodegenerative disease and is characterized by the loss of dopaminergic neurons in the substantia nigra and the formation Lewy bodies. ⍺-Synuclein is a major structural component of Lewy bodies. It is well established from in vitro and in vivo experiments that ⍺-Syn forms aggregates and may contribute to toxicity. The overarching goal of this project was to characterize the distribution of aggregation states of ⍺-Synuclein associated with PD. Human ⍺-Synuclein was successfully expressed in Drosophila melanogaster using the Da-Gal-4 system and protein expression was confirmed by a Western blot. SDD-AGE was used to qualitatively measure aggregation states and it was found that ⍺-Syn does from aggregates in adult flies but not in the 3rd instar larval developmental stage