36057 research outputs found
Sort by
A multimodal machine learning framework for diagnosis of otitis media with effusion using 3D wideband acoustic immittance
Get PDFEnvironmental consequences of interacting effects of changes in stratospheric ozone, ultraviolet radiation, and climate : UNEP Environmental Effects Assessment Panel, update 2024
Get PDFThis Assessment Update by the Environmental Effects Assessment Panel (EEAP) of the United Nations Environment Programme (UNEP) addresses the interacting effects of changes in stratospheric ozone, solar ultraviolet (UV) radiation, and climate on the environment and human health. These include new modelling studies that confirm the benefits of the Montreal Protocol in protecting the stratospheric ozone layer and its role in maintaining a stable climate, both at low and high latitudes. We also provide an update on projected levels of solar UV-radiation during the twenty-first century. Potential environmental consequences of climate intervention scenarios are also briefly discussed, illustrating the large uncertainties of, for example, Stratospheric Aerosol Injection (SAI). Modelling studies predict that, although SAI would cool the Earth’s surface, other climate factors would be affected, including stratospheric ozone depletion and precipitation patterns. The contribution to global warming of replacements for ozone-depleting substances (ODS) are assessed. With respect to the breakdown products of chemicals under the purview of the Montreal Protocol, the risks to ecosystem and human health from the formation of trifluoroacetic acid (TFA) as a degradation product of ODS replacements are currently de minimis. UV-radiation and climate change continue to have complex interactive effects on the environment due largely to human activities. UV-radiation, other weathering factors, and microbial action contribute significantly to the breakdown of plastic waste in the environment, and in affecting transport, fate, and toxicity of the plastics in terrestrial and aquatic ecosystems, and the atmosphere. Sustainability demands continue to drive industry innovations to mitigate environmental consequences of the use and disposal of plastic and plastic-containing materials. Terrestrial ecosystems in alpine and polar environments are increasingly being exposed to enhanced UV-radiation due to earlier seasonal snow and ice melt because of climate warming and extended periods of ozone depletion. Solar radiation, including UV-radiation, also contributes to the decomposition of dead plant material, which affects nutrient cycling, carbon storage, emission of greenhouse gases, and soil fertility. In aquatic ecosystems, loss of ice cover is increasing the area of polar oceans exposed to UV-radiation with possible negative effects on phytoplankton productivity. However, modelling studies of Arctic Ocean circulation suggests that phytoplankton are circulating to progressively deeper ocean layers with less UV irradiation. Human health is also modified by climate change and behaviour patterns, resulting in changes in exposure to UV-radiation with harmful or beneficial effects depending on conditions and skin type. For example, incidence of melanoma has been associated with increased air temperature, which affects time spent outdoors and thus exposure to UV-radiation. Overall, implementation of the Montreal Protocol and its Amendments has mitigated the deleterious effects of high levels of UV-radiation and global warming for both environmental and human health
New vegetation stress assessment approach via WorldView-3 imagery, validated with UAV thermal imaging
No full textSecret museums, occult archaeology, and the counter-public sphere : the British Museum’s Secretum 1865-1938
No full textThe mediating role of digital innovation capability on the relationship between organisational agility and performance : the case of the UK arts and culture sector
Get PDFUnderstanding student engagement in the post-COVID-19 environment to create more inclusive support, equitable engagement and success : a collaborative study
No full text
A novel fluorescent sensing platform for glutathione based on Förster resonance energy transfer and aggregation-induced emission
No full textGlutathione (GSH) plays essential roles in anti-oxidation and detoxification within the human body. An imbalance in its concentration can lead to serious health conditions. Therefore, accurate monitoring of GSH is critical for maintaining human health. In this study, we present a novel GSH detection method that enhances the fluorescence of α-lipoic acid-functionalized gold nanoclusters (LA@Au NCs) through aggregation induced by zinc and nitrogen co-doped carbon dots (Zn@N-CDs). Additionally, the fluorescence of Zn@N-CDs (donor) decreases upon adding LA@Au NCs (acceptor), indicating Förster resonance energy transfer (FRET) between them. In the presence of GSH, complexation with Zn2+ on the N-CD surface disrupts both the aggregation induced emission (AIE) and FRET mechanisms. This disruption leads to the restoration of N-CD fluorescence while simultaneously quenching the fluorescence of LA@Au NCs. Under optimized conditions, the fluorescence response ratio (F465/F670) is directly proportional to the concentration of GSH within a linear dynamic range of 0.1–90 µM, with a detection limit (S/N = 3) of 0.03 µM. This novel combination paves the way for the development of fluorescent probes for detecting various molecules and biomolecules