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Tongue and jaw movement measured by 3D motion capture during mastication
新潟大学Niigata University博士(歯学)新大院博(歯)第563
障害者福祉施設通所知的障害者を対象とした歯磨きの実行機能支援として視覚支援媒体を用いた歯科衛生士による歯磨き指導の効果
新潟大学Niigata University博士(口腔保健福祉学)新大院博(口)第29
人工股関節全置換術後鎮痛法としてのアセトアミノフェン経静脈投与と経静脈的患者管理鎮痛法との比較 : 多施設ランダム化比較試験
新潟大学Niigata University博士(医学)Background: Opioids often need to be discontinued because they cause nausea, whereas the administration of intravenous acetaminophen (APAP) causes less nausea and vomiting. This study aimed to compare the effects of fentanyl-based intravenous patient-controlled analgesia (IV-PCA) and intravenous APAP on pain and nausea after total hip arthroplasty (THA). Methods: We prospectively investigated primary THA patients who underwent the anterolateral supine approach at four centers between October 2021 and October 2022. The patients (n = 178) were divided randomly into IV-PCA (n = 88) and APAP groups (n = 90). Rest pain, motion pain, and nausea were assessed using NRS scores. Results: Compared with the APAP group, the IV-PCA group experienced significantly greater resting pain and nausea on postoperative day 1. A correlation was found between preoperative and postoperative pain. Postoperative nausea at 8 h was significantly correlated with pain at rest at 4 h (r = 0.193), 8 h (r = 0.194), day 1 (r = 0.245), and day 2 (r = 0.188) after surgery. Early postoperative pain and nausea correlated with subsequent pain and nausea. Conclusions: Intravenous APAP is associated with less pain and nausea and is superior to IV-PCA.Sakai, Y.; Imai, N.; Miyasaka, D.; Suzuki, H.; Horigome, Y.; Takahashi, Y.; Kawashima, H. Comparison of Intravenous Acetaminophen and Intravenous Patient-Controlled Analgesia Fentanyl after Total Hip Arthroplasty: A Multicenter Randomized Controlled Trial. J. Clin. Med. 2023, 12, 7445. https://doi.org/10.3390/jcm12237445新大院博(医)第1230
リンパ節転移陽性非小細胞肺癌の外科治療成績
新潟大学Niigata University博士(医学)Abstract: This study aimed to investigate the appropriate subgroups for surgery and adjuvant chemotherapy in patients with non-small-cell lung cancer (NSCLC) and nodal metastases. We retrospectively reviewed 210 patients with NSCLC and nodal metastases who underwent surgery and examined the risk factors for poor overall survival (OS) and recurrence-free probability (RFP) using multivariate Cox proportional hazards analysis. Pathological N1 and N2 were observed in 114 (52.4%) and 96 (47.6%) patients, respectively. A single positive node was identified in 102 patients (48.6%), and multiple nodes were identified in 108 (51.4%). Multivariate analysis revealed that vital capacity 4.0 cm (HR: 1.534, 95% CI: 1.035-2.133), and multiple-node metastases (HR: 2.283, 95% CI: 1.517-3.955) were significant independent risk factors for poor OS. Tumor size > 4.0 cm (HR: 1.780, 95% CI: 1.237-2.562), lymphatic permeation (HR: 1.525, 95% CI: 1.053-2.207), and multiple lymph node metastases (HR: 2.858, 95% CI: 1.933-4.226) were significant independent risk factors for recurrence. In patients with squamous cell carcinoma (n = 93), there were no significant differences in OS or RFP between those who received platinum-based adjuvant chemotherapy (n = 25) and those who did not (n = 68), at p = 0.690 and p = 0.292, respectively. Multiple-node metastases were independent predictors of poor OS and recurrence. Patients with NSCLC and single-node metastases should be considered for surgery despite N2 disease. Additional treatment with platinum-based adjuvant chemotherapy may be expected, especially in patients with squamous cell carcinoma.Shimizu, Y.; Koike, T.; Hasebe, T.; Nakamura, M.; Goto, T.; Toyabe, S.-i.; Tsuchida, M. Surgical Treatment Outcomes of Patients with Non-Small Cell Lung Cancer and Lymph Node Metastases. Cancers 2023, 15, 3098. https://doi.org/10.3390/cancers15123098新大博(医)第1832
外洋海水中超微量Te(IV)・Te(VI)化学種の定量分析法確立および東部インド洋におけるTe化学種の南北断面分布と海洋学的特徴の関係
新潟大学Niigata University博士(理学)新大院博(理)第499
イネのサイトカイニン情報伝達経路における非生物ストレスへの適応と耐性に関与する制御遺伝子のゲノムワイド解析および機能解析
新潟大学Niigata University博士(農学)新大院博(農)第250