Niigata University Medical and Dental Hospital
Niigata University Academic RepositoryNot a member yet
33813 research outputs found
Sort by
成人期の愛着スタイルが、周産期を通じてうつ病と不安を介して絆形成に与える影響
Get PDF新潟大学博士（医学）Background
Few studies have investigated relationships among adult attachment style, depression, anxiety, and prenatal mother-to-fetus/postnatal mother-to-infant bonding in perinatal women, with varied findings. We examined the direct effects of adult attachment style on bonding as well as indirect effects via depression and anxiety.
Methods
In this prospective observational, longitudinal cohort study, 1897 Japanese perinatal women were recruited from 34 obstetric institutions in Niigata Prefecture. Adult attachment was assessed at T1 (early pregnancy), with depression/anxiety and bonding assessed at T1, T2 (late pregnancy), and T3 (postpartum). We used parallel process latent growth curve modeling to examine direct effects of the T1 adult attachment style on bonding across the perinatal period, as well as the mediating roles of depression and anxiety over three time points.
Results
No significant direct effects of adult attachment on bonding trajectories were observed. However, significant indirect effects were found, suggesting that adult attachment style influenced both the initial levels and change in bonding via its impact on the developmental trajectories of both depression and anxiety, with distinct roles for each mediator. The model fit was good to acceptable.
Limitations
This study was limited by reliance on self-report measures, geographically restricted samples, and the absence of long-term follow-up.
Conclusion
We found that the impact of adult attachment style on bonding was mediated by depression and anxiety across the perinatal period. Early screening and intervention for depressive and anxiety symptoms related to the mother's attachment toward her romantic partner is essential to prevent bonding difficulties.Muhammad Dwi Wahyu, Ekachaeryanti Zain, Yuichiro Watanabe, Naoki Fukui, Koyo Hashijiri, Takaharu Motegi, Maki Ogawa, Jun Egawa, Koji Nishijima, Toshiyuki Someya,
Impact of adult attachment style on bonding mediated by depression and anxiety across the perinatal period,
Journal of Affective Disorders,
Volume 388,
2025,
119763,
ISSN 0165-0327,
https://doi.org/10.1016/j.jad.2025.119763.
(https://www.sciencedirect.com/science/article/pii/S0165032725012054)新大院博（医）第1281
急性肺塞栓症患者における治療前のCT所見と治療後の肺灌流血液量の持続的低下との関連性
Get PDF新潟大学Niigata University博士（医学）The purpose of this study was to evaluate pre-treatment CT findings in patients with acute pulmonary embolism (PE) and determine the imaging findings associated with residual hypoperfused segments in post-treatment lung perfused blood volume (LPBV). We evaluated 91 patients with acute PE who underwent dual-energy CT before and after treatment. The location of thrombi (proximal or distal) and patency of the pulmonary artery (occlusive or non-occlusive) were recorded using pre-treatment computed tomography pulmonary angiography (CTPA). Residual hypoperfusion was defined as a perfusion-decreased area seen in both the pre- and post-treatment LPBVs. The association of the location of the thrombus and vascular patency of pre-treatment CTPA with residual hypoperfusion on a segmental and patient basis was examined. In the segment-based analysis, the proportion of residual hypoperfusion in the proximal group was significantly higher than that in the peripheral group (33/125 [26.4%] vs. 9/87 [10.3%], P = 0.004). Patient-based analysis also showed that the proportion of residual hypoperfusion in patients with pre-treatment proximal thrombus was significantly higher than those without (16/42 [38.1%] vs. 3/25 (12.0%); P = 0.022). Pre-treatment vascular patency was not significantly associated with residual hypoperfusion (P > 0.05). Therefore, careful follow-up is necessary, especially in patients with proximal thrombi.Hirata T, Yoshimura N, Yagi T, Yamazaki M, Horii Y, Ishikawa H. Association between pre-treatment computed tomography findings and post-treatment persistent decrease in lung perfusion blood volume. Sci Rep. 2024 May 24;14(1):11919. doi: 10.1038/s41598-024-62890-7.新大院博(医)第1251
ニードリングを併用した眼内法によるエクスプレス抜去術
Get PDF新潟大学博士（医学）Purpose
We present an ab interno removal technique combined with a needling procedure for a malpositioned Ex-PRESS glaucoma shunt.
Study design
Retrospective case series.
Methods
This study examined four cases of malpositioned Ex-PRESS shunts. Needle bleb revision was performed to expand the space under the scleral flap and bleb area. Clinical data, including corneal endothelial cell density (ECD), intraocular pressure (IOP), and anterior segment optical coherence tomography images (AS-OCT), were retrieved from clinical records.
Results
All four cases underwent ab interno shunt removal combined with needle bleb revision without any serious complications. In three cases of anterior shunt malposition, a reduction in ECD was apparent before surgery but remained relatively stable after surgery. In one patient with posterior shunt malposition, shunt occlusion was suspected before surgery, but bleb formation and IOP improved after surgery. IOP was 8 mmHg to 21 mmHg (median, 10.5 mmHg) before surgery and 5 mmHg to 17 mmHg (median, 10 mmHg) 12 months after surgery. No additional glaucoma surgery was required within the first 12 months; however, after 12 months, two patients required additional glaucoma surgery.
Conclusion
Ab interno Ex-PRESS device removal combined with bleb needling is an important procedure in patients with malpositioned Ex-PRESS devices.Kobayashi, D., Akagi, T., Togano, T. et al. Ab interno removal of malpositioned ex-press glaucoma device combined with bleb needling. Jpn J Ophthalmol 69, 577–582 (2025). https://doi.org/10.1007/s10384-025-01203-5新大院博（医）第1273