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    Governance for Forests and Stakes of National Park Creation In Gabon– Case of the Lopé National Park

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    Les forêts de la Lopé au centre du Gabon sont au coeur d’enjeux multiples. À la logique de type ressourciste qui a prévalu dans les milieux naturels qui la composent, l’impératif de la protection des ressources naturelles imposent aux divers acteurs de faire évoluer leurs pratiques et la valeur octroyée à cet ensemble. Cette démarche est d’autant plus nécessaire qu’elle s’inscrit dans un contexte international promouvant la conservation des systèmes socioécologiques par la mise en place d’aires protégées. L’établissement du parc national de la Lopé en août 2002 répond à cette vision parfois aux dépens des actifs de l’industrie forestière. La mise en place de cet outil de la conservation s’inscrit dans un processus d’élaboration de texte de loi et d’institutions visant à sanctuariser des portions de territoire à fort potentiel écologique et riche de son patrimoine culturel. Le parc national de la Lopé représente d’ailleurs le cas le plus concret et avancé de gouvernance forestière au Gabon. Cet article s’appuie sur les travaux de terrain réalisés par ses auteurs entre 2018 et 2019 pour expliciter les ressorts la gouvernance des forêts à travers l’étude d’acteurs et d’enjeux autour du parc national de la Lopé.The forests of Lopé in central Gabon lie at the heart of multiple stakes. Supplanting the resourcist rationale that prevailed in the treatment of the natural environments that these forests comprise, the imperative of protecting natural resources requires that the various players adapt their practices and the value they attribute to this entity. This approach is particularly necessary since it is placed in an international context that promotes the conservation of socio-ecological systems through the establishment of protected areas. The Lopé National Park was established in August 2002 and conforms to this vision, sometimes at the expense of forest industry workers. Implementing this conservation tool has required legislation to be passed and bodies set up to safeguard portions of the territory that have high ecological potential and a rich cultural heritage. The Lopé National Park is indeed the most advanced, concrete case of forest governance in Gabon. This article relies on field work conducted by its authors between 2018 and 2019 to pinpoint the mechanisms of forest governance through the study of the actors and the stakes connected with the Lopé National Park

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    Table of contents 2019

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    Uteria naghanensis n. sp. (Dasycladale) du Maastrichtien supérieur d' Iran

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    A new dasycladalean alga is described as Uteria naghanensis n. sp. from the late Maastrichtian Tarbur Formation of the Zagros Zone, SW Iran. It is a small to medium-sized, rather well calcified species with small articles each bearing one fertile ampulla, alternating with close-set verticils of numerous sterile laterals. Another characteristic is its comparably wide main axis. The genus Uteria Michelin was so far only known from the Paleogene (Danian-Lutetian). The discovery of U. naghanensis n. sp. in inner platform wackestone of the Tarbur Fm. documents the origination of the genus already in the uppermost Cretaceous within an area belonging to the Arabian Plate.Une algue dasycladale nouvelle est décrite comme Uteria naghanensis n. sp. du Maastrichtien supérieur de la Formation de Tarbur, Zone de Zagros, sud-ouest de l'Iran. Il s'agit d'une espèce de taille petite à moyenne, assez bien calcifiée, avec des petits articles portant chacun une ampoule fertile, disposés en alternance avec des verticiles serrés de nombreuses latérales stériles. Elle est aussi caractérisée par son axe principal assez large. Le genre Uteria Michelin n'était jusqu'à présent connu que dans le Paléogène (Danien-Lutétien). La découverte d'U. naghanensis n. sp. dans des boues bioclasiques de plate-forme interne de la Formation de Tarbur atteste de l'apparition du genre dès la partie terminale du Crétacé dans un domaine relevant de la Plaque Arabe

    XRCC2 (X-ray repair cross complementing 2)

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    XRCC2 is one of five somatic RAD51 paralogs, all of which have Walker A and B ATPase motifs. Each of the paralogs, including XRCC2, has a function in DNA double-strand break repair by homologous recombination (HR). However, their individual roles are not as well understood as that of RAD51 itself. The XRCC2 protein forms a complex (BCDX2) with three other RAD51 paralogs, RAD51B, RAD51C and RAD51D. It is believed that the BCDX2 complex mediates HR downstream of BRCA2 but upstream of RAD51, as XRCC2 is involved in the assembly of RAD51 into DNA damage foci. XRCC2 can bind DNA and, along with RAD51D, can promote homologous pairing in vitro. Consistent with its role in HR, XRCC2-deficient cells have increased levels of spontaneous chromosome instability, and exhibit hypersensitivity to DNA interstrand crosslinking agents such as mitomycin C and cisplatin as well as ionizing radiation, alkylating agents and aldehydes. XRCC2 also functions in promoting DNA replication and chromosome segregation. Biallelic mutation of XRCC2 (FANCU) causes the FA-U subtype of FA, while heterozygosity for deleterious mutations in XRCC2 may be associated with an increased breast cancer risk. XRCC2 appears to function 'downstream' in the FA pathway, since it is not required for FANCD2 monoubiquitination, which is the central step in the FA pathway. Clinically, the only known FA-U patient in the world exhibits severe congenital abnormalities, but had not developed, by seven years of age, the bone marrow failure and cancer that are often seen in patients from other FA complementation groups

    t(1;11)(q24;p15) NUP98/PRRX1

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    NUP98 is considered as one of the most promiscuous genes in hematologic malignancies due to its participation in chromosomal translocations with up to 30 different partner genes, including homeodomain transcription factors

    der(20)t(1;20)(q12-21;p13) in hematological malignances

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    Review on der(20)t(1;20)(q12-21;p13), with data on clinics, and the genes involved

    Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2019, n°1 - Full issue

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    t(2;11)(p21;q24) MIR125B1/?

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    Review on t(2;11)(p21;q24), with data on clinics, and the genes involved

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