Archivio istituzionale della ricerca - Università degli Studi di Venezia Ca' Foscari
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    In dialogo con Bruna Bianchi. Note a margine di «Non resistere al male con il male». Obiezione di coscienza e pacifismo nel pensiero di Tolstoj

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    In Dialogue with Bruna Bianchi. Marginal Notes on «Not Resisting Evil with Evil»: Conscientious Objection and Pacifism in Tolstoy’s Thought. The article examines Tolstoy’s radical pacifism in dialogue with Bruna Bianchi’s book on the same subject. Tolstoy advocated for disarmament and nonviolence as the sole path to peace. His ethical Christianity, based solely on the precept «Love your neighbour as yourself», aimed at the individual’s inner transformation. This led to his call for conscientious objection and his interest in the Doukhobors, a persecuted non-violent religious community in Russia, whom the writer helped to emigrate. The article concludes by comparing Tolstoy with his «eternal rival» Dostoevsky: despite their opposing views on humanity, they shared a common belief in the «ridiculous dream» of universal brotherhood, attainable through different paths

    Surface radiation budget data in a bipolar perspective: observations, comparison and exploiting for products

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    Clouds modulate the net radiative flux interacting with both shortwave and longwave radiation, but the uncertainties regarding their effect in polar regions are especially high, because ground observations are lacking and evaluation through satellites is made difficult by the high surface reflectance. In this work, the radiative regimes and sky conditions for five different stations, two in the Arctic (Ny-Ålesund, 78.92°N, 11.93°E, Barrow, 71.32°N, 156.61° W) and four in Antarctica (Neumayer, 70.68°S, 8.27°W; Syowa, 69.01°S, 39.58°E; South Pole, 90°S, 0°E ; DomeC, 75.01°S, 123.33°E) will be presented, considering the decade between 2010 and 2020. Measurements of broadband shortwave and longwave radiation components (both downwelling and upwelling) are collected within the frame of the Baseline Surface Radiation Network (BSRN) (Driemel et al. 2018). Observations, together with identification of the clear sky and overcast conditions will be compared with ERA5 reanalysis (Herschbach et al., 2023). Furthermore, the identified conditions based on estimated cloud fraction will serve as labels for a machine learning classification task, leveraging algorithms such as Random Forest and Long Short-Term Memory (LSTM) networks (i.e. Zeng et al., 2021; Sedlar et al., 2021). These models incorporate features including global and diffuse shortwave radiation, downward longwave radiation, solar zenith angle, surface air temperature, relative humidity, and the ratio of water vapor pressure to surface temperature. The Random Forest model will also compute feature importance, identifying the most influential variables in predicting sky conditions and providing insights into the relationships between these meteorological factors

    Ritratto di Lei - Intervista a Rachele Bastreghi

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    Rachele Bastreghi Musicista, chanteuse e anima femminile dei Baustelle, Rachele Bastreghi è una delle icone più riconosciute e ammalianti della scena pop-rock italiana. Con i Baustelle (insieme a Francesco Bianconi e Claudio Brasini), Rachele ha pubblicato tra il 2000 e il 2023 nove album di studio, una colonna sonora e un disco live. Il suo contributo ai Baustelle si è dimostrato essenziale per l’affermazione della band come uno dei più interessanti esempi di alternative pop italiano. Nel 2015, Rachele ha iniziato una nuova avventura come autrice, offrendo una sua canzone, Ci rivedremo poi a Patty Pravo, per l’album Eccomi. La richiesta di partecipazione con un cameo a una serie tv ha poi dato vita nel 2015 a un EP intitolato Marie, una raccolta di canzoni e cover ispirata al suono, alla musica e alle forti personalità artistiche degli anni Settanta. Nel 2021 ha pubblicato Psychodonna (Warner Music Italy), il suo primo ‘vero’ album da solista prodotto da Mario Conte (Colapesce, Meg). Il titolo esprime la personalità sfaccettata e apparentemente contrastante della cantautrice, messa in musica in una raccolta di canzoni che mescolano sonorità anni Ottanta e Novanta, elettronica, echi retrò e french pop. Dal 2021 si affianca nell’attività live di Rachele la collaborazione con il disegnatore Alessandro Baronciani, prima per il progetto Quando tutto diventò blu e a seguire per il singolo/ video di Storia, il brano apripista contenuto nel nuovo progetto di Baronciani, RagazzaCD. Nel 2024 va in scena per la prima volta a Firenze, Milano e Roma il concerto Un giorno da Psychodonna – Concerto disegnato

    A mutational hotspot in TUBB2A associated with impaired heterodimer formation and severe brain developmental disorders

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    Introduction: Microtubules are essential components of the neuronal cytoskeleton. The α- and β-tubulins, variably expressed in the central nervous system, play key roles in neurogenesis and brain development. Pathogenic variants in TUBB2A have recently been identified as an ultra-rare cause of pediatric neurodevelopmental disorders (NDDs). However, the neurological and behavioral manifestations, genotype–phenotype correlations, and underlying disease mechanisms remain poorly understood due to the limited number of reported families. Methods: We describe a cohort of families presenting with microcephaly, global developmental delay, speech impairment, seizures and/or EEG abnormalities, movement disorders and severe behavioral disorders. Clinical assessments and brain imaging studies were conducted over a 10-year follow-up period. Genetic analysis was performed via whole-exome sequencing (WES), and structural modeling was used to investigate the functional impact of the identified variants. Results: WES revealed a novel recurrent heterozygous pathogenic variant in TUBB2A (NM_001069.3:c.1172G > A; NP_001060.1:p.Arg391His), identified as the cause of disease in multiple affected individuals from unrelated families. Comparative analysis with previously reported TUBB2A de novo variants confirmed that this novel recurrent mutation affects a highly conserved Arg391 residue within the longitudinal E-site heterodimer interface. Computational modeling demonstrated that the variant disrupts α/β-tubulin heterodimer formation, impairing binding stability at this critical interaction site. Discussion: Our findings expand the phenotypic and genotypic spectrum of TUBB2A-related disorders and identify Arg391 as a mutational hotspot linked to severe brain developmental disorders due to aberrant tubulin dynamics, highlighting the disruption of the α/β-tubulin heterodimer formation as the disease mechanism associated to this novel hotspot variant. These results provide new insights into disease mechanisms and offer a foundation for potential future therapeutic approaches aimed at stabilizing α/β-tubulin interactions

    The truth of fairy tale in Simone Weil

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    In this article, the dialogue between philosophy and literature unfolds through the prism of Simone Weil’s meditation on fairy tales. With their distinctive narrative structures and evocative language, fairy tales transport us into a realm of suspension – one that transcends the coordinates of ordinary space and time, embodying a symbolic and spiritual dimension. Although they recount fantastic events that never happened, fairy tales do not deceive; rather, they convey spiritual truths through symbolic figures and allegorical tableaux. A lover of Grimm’s fairy tales, Simone Weil never considered them works of pure fantasy. In her view, fairy tales held a profound mystical resonance. Far from being simple entertainment for children, they unveil an inner dimension capable of opening the soul to the Good and to God

    Writing and Religious Traditions in Roman Venetia. Connections and Changes in Two Sanctuaries at Ateste and Lagole

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    This article explores the complex and multifaceted relationship between writing and religious traditions in ancient Roman Venetia , with particular attention to two prominent cult sites: the Reitia sanctuary at Este (ancient Ateste ) and the alpine sanctuary at Lagole di Calalzo di Cadore. Through a close analysis of the extant epigraphic record, the study identifies patterns of continuity and transformation that shaped the historical trajectories of these sanctuaries as Roman influence progressively took hold in the region. The primary aim is to reconstruct the timing and dynamics of the linguistic, religious and social processes of acculturation that informed the integration of both centres into the Roman world.Cet article explore la relation complexe et multiforme entre l’écriture et les traditions religieuses dans l’ancienne Vénétie romaine, en accordant une attention particulière à deux sites de culte importants : le sanctuaire de la Reitia à Este (ancien Ateste) et le sanctuaire alpin de Lagole di Calalzo di Cadore. Grâce à une analyse minutieuse des documents épigraphiques existants, l’étude identifie les modèles de continuité et de transformation qui ont façonné les trajectoires historiques de ces sanctuaires au fur et à mesure que l’influence romaine s’est progressivement imposée dans la région. L’objectif principal est de reconstruire le calendrier et la dynamique des processus d’acculturation linguistique, religieuse et sociale qui ont contribué à l’intégration des deux centres dans le monde romain

    The glass assemblage from San Pietro in Castello: tracing glass technology and innovations in the Venetian lagoon

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    This study presents the results of a comprehensive archaeometric investigation of a glass assemblage from the early medieval levels of San Pietro in Castello (Olivolo, Venice), a site of strategic importance during the formative stages of the city. A total of 45 samples, including finished vessels, architectural glass, production waste and a crucible, were analysed using SEM-EDS, EMPA, and LA-ICP-MS. As for glassmaking technology, the results reveal various colouring and opacification strategies, including the use of metallurgical by-products such as cobalt-bearing slag and the co-occurrence of calcium antimonates and lead stannates for the realization of decorative threads. Furthermore, the analysis of the steatite crucible and adhering glass provides insight into contamination processes and their implications for provenance studies. As for glass provenance, the chemical composition shows a near-equal distribution of Levantine and Egyptian natron glass, though differently distributed from a chronological standpoint (Levantine only in later phases). Of particular interest is also the finding of two plant-ash based glass samples, with the earliest one dating to the 8th century and attributed to Syro-Levantine production. Overall, the findings highlight Venice’s early involvement in the technological transition from natron- to plant ash-based glass and suggest that the San Pietro in Castello site may have played a pivotal role in the distribution and reworking of imported raw materials

    Exploring the advantages of automated stations to retrieve continuous weather and snow-related data in high-elevation sites (Monte Rosa massif - Western Italian Alps)

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    Anthropogenic climate change is strongly impacting mountain regions. The warming rate observed for the Alpine Region is well above the global average. Moreover, crucial water reservoirs such as glacier ice and seasonal snowpack are extremely susceptible to changes due to their inherent dependence both on the persistence of below 0 °C temperatures and the amount of solid precipitation. In recent years, the European Alps have experienced multiple seasons of intense deficit of snow precipitation compared to historical records. Given that the hydrological assets of the Western Italian Alps have a crucial role in the economic activities of Northern Italy, it is necessary to enhance the monitoring and the studies performed on the region. One of the most pressing criticalities that arise dealing with the study of the Alps is the growing need of direct measurements of meteorological and snow-related variables at high-elevation sites. To address this gap, a network of automated stations (ASs) has been established on the Monte Rosa massif in Western Alps, on the border between the Italian regions of Piedmont and Aosta Valley. The network’s responsibility falls under the Laboratory of Alpine Climatology, LabClima, of the University of Turin. Firstly, we present the data collected by the AS installed in the LTER site - Mosso Institute (45°52’30’’ N; 7°52’18’’ E; 2900 m a.s.l.), which is also equipped with sensors for Snow Water Equivalent (SWE) measurement based respectively on Cosmic Rays Sensors (CRS) and Global Navigation Satellite System (GNSS) technologies. The daily SWE datasets are compared with field data collected during measurement campaigns to investigate their potential to increase the temporal density and availability of data for remote and harsh mountain environments. We also present the data acquired by another AS (45°53'46.53"N; 7°50'56.96"E; 3500 m a.s.l.) established in September 2024 near the Garstelet Glacier. The sensors installed retrieve continuous data regarding the main meteorological variables (e.g., air temperature, atmospheric pressure, wind speed and direction, relative humidity, solar radiation, precipitation, and snow height) as well as the temperature of the snowpack layers (measured at 50 cm intervals from the ground level up to 2 m height) and the type of precipitation thanks to the presence of a disdrometer. The variety of data collected by this AS is unprecedented at such elevation in the Italian Alps and could help to address the present gaps of information for end users and future scientific research

    From emergency to longer-term assistance? The EU support for displaced Ukrainians.

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    The activation of the Temporary Protection Directive (TPD) in 2022 was a landmark moment of EU solidarity, providing essential support to over five million displaced Ukrainians. While the Directive’s continuous extension demonstrates the EU’s strong commitment, it also underlines the pressing need to shift the focus to a long‐term assistance strategy. This analysis explores various long-term options, highlighting Ukraine’s EU accession as the most promising path forward. The accession process offers a durable and comprehensive solution, ultimately providing permanent rights and stability for Ukrainians while reinforcing the EU’s broader commitment to regional security and integration

    Electrochemical Chemo‐ and Regioselective Heterofunctionalization of Tropones via C(sp2)-H Derivatization

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    A general electrochemical synthetic procedure for the site-selective heterofunctionalization of activated tropones is documented. Detailed voltametric analysis and quantum chemistry calculations enabled the development of a predictive model for the process efficiency, accounting for both reactivity and regioselectivity. Monoand poly-halogenation, nitration, sulfonation, and thiocyanation protocols are successfully executed starting from inexpensive sodium salts under oxidative electrolytic conditions (35 examples, isolated yields up to 95%, faradaic efficiencies up to 95%). The implementation of an iterative electrochemical/metal-catalyzed cross-coupling synthetic strategy, along with the adaptation of the protocol for the preparation of biologically relevant tropolone derivatives, underscores the generality and robustness of the methodology

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