1923 research outputs found

    Theology, religion, and dystopia

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    Chapter 8, Katniss, Christos: Sacrifice and Salvation in Scripture and Young Adult Dystopian Novels Shayna Sheinfeldhttps://idun.augsburg.edu/monographs/1085/thumbnail.jp

    Myosin 8 Recombinant Plasmid within Tetrahymena Thermophilla

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    https://idun.augsburg.edu/zyzzogeton/1025/thumbnail.jp

    Mindfulness Meditation: Stress Management for Black Maternal Patients

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    Pregnant Black women are at risk of suffering from stress related illnesses. The maternal Black population faces a unique set of challenges that increase their risk to preventable conditions. Lack of effective stress management skills can make them even more susceptible to deteriorating health outcomes. An extensive review of the literature highlighted that the use of holistic healing modalities such as mindfulness meditation leads to reduced stress levels. Therefore, family nurse practitioners in primary care will need to be well informed on non-pharmacological ways to help their patients gain effective coping skills for positive health outcomes. The purpose of this scholarly project was to educate pregnant Black women about health risk factors and the effects of stress. Furthermore, the implementation of this project focused on applying mindfulness meditation practices and examining the impact mindfulness meditation had on their stress levels. A one-hour long virtual class directed towards educating Black pregnant women on health risks and stress management through mindfulness meditation was provided. There were a total of 10 volunteers, all of whom shared a positive correlation with stress reduction and meditative techniques. Implications for advanced nursing practice includes sharing knowledge about integrative therapies that will benefit the health of pregnant Black women and working to form collaborations between community members and providers to ensure high quality care

    What Alternative Models are Effective in Improving Health Outcomes in Children With Obesity in the United States?

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    Background: Obesity in children has increased at an alarming rate in the past three decades and has been associated with multiple comorbidities. This literature review has been focused on pediatric obesity management research utilizing Family-Based Therapy, community-centered interventions, behavioral modifications, and implementations for management within the Primary Care setting. Purpose: There has not been an established standard of care for children suffering from obesity. This investigation was focused on the question; What alternative models are effective in improving health outcomes in children with obesity in the United States? Methods: A comprehensive literature review was conducted using Pub Med advanced search engine. Search terms included pediatric, childhood, adolescent, overweight, obesity, BMI, management, prevention, and treatment. Exclusion criteria terms were endocrine, pregnancy, and adulthood. Conclusion: Research designs that have shown success with BMI reduction include social and family support, education, limiting screen time, reduced caloric intake, and increased activity levels. The most successful programs for management include multiple factors from this list and are interventions for more than three months. When looking at long-term sustainability treatment duration should extend longer than six months. Treatment that is specific to a patient’s unique circumstances has shown the greatest success in meeting treatment goals. Family-Behavioral Therapy has been shown to be the most effective in lifestyle changes that are sustainable long-term for pedantic patients of any age and their families. Further research does need to be conducted regarding the long-term sustainability of treatment that is cost-effective

    How Might Ultrasound Guided Regional Anesthesia (UGRA) Provide Better Analgesic Care Compared to Opioids in Both Hospital, And Remote Environments

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    As medical technology continues to evolve and becomes more portable, frontline austere medical practitioners can more safely diagnose, identify, and treat life-threatening emergencies more accurately. Point of care ultrasound (POCUS) has rapidly become an adjunct of care in prehospital, emergency department, intensive care, and primary care settings and with a general understanding of sonoanatomy, clinicians can identify, safely diagnose medical emergencies, and conduct an array of procedures with ultrasound devices now small enough to fit inside a pocket.1 One of such procedures, is the use of ultrasound-guided regional anesthesia (UGRA) to manage acute pain. With near instantaneous pain relief and taught to providers in a relatively short amount of time; traumatic injuries, surgical procedures, and even some chronic issues can be treated without impeding a patient’s level of consciousness. What was once considered a rather esoteric procedure can have a significant impact with hospital and international medical providers where access to opioids may be difficult to obtain and the risk of their effects can be too unpredictable. Unfortunately, lack of intra-departmental collaboration, standardized training, and peer reviewed literature remain significant issues for the future of UGRA and more research remains needed

    Dual Antiplatelet Therapy With Ticagrelor vs Clopidogrel in Patients With Acute Coronary Syndrome

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    Background: Dual antiplatelet therapy (DAPT) is an effective secondary prevention and an essential component of treatment after patients suffering from acute coronary syndrome (ACS). Recently, clinicians rapidly switched to DAPT with ticagrelor as the preferred treatment option after it was introduced in 2011. Compared to clopidogrel, ticagrelor is not a prodrug and does not require metabolic activation to inhibit the platelet P2Y12 receptor. It is the first reversible oral P2Y12 receptor antagonist; and its effect on platelet inhibition is more pronounced compared to clopidogrel. Purpose: The purpose of this comprehensive review was to evaluate the efficacy and safety data of ticagrelor when compared with clopidogrel in ACS patients. Methods: A comprehensive literature review was conducted using Tripdatabases and Pubmed search engines was searched through June 2022 using the terms: “dual antiplatelet therapy,” “antiplatelet monotherapy,” “ticagrelor vs clopidogrel,” “reduce recurrent atherothrombotic events,” “cardiovascular adverse events,” “coronary heart disease,” “acute coronary syndrome,” “myocardial infarction.” Inclusion criteria were recently published studies (at least 15 studies within the last five years from the day this review was performed) comparing the efficacy of ticagrelor with clopidogrel or placebo. The type of trials could be retrospective studies or prospective randomized controlled studies with complete data and reportable clinical outcomes. Exclusion criteria were case reports, repeated publications, animal experiments, and studies that were poorly designed with errors, incomplete data, or without clinical outcomes. Conclusions: Through the literature review from many blinded, randomized controlled trials and studies, ticagrelor has successfully shown its superior efficacy in reducing the rate of cardiovascular adverse events in ACS patients and shown no significant difference in the rate of major bleeding between ticagrelor and clopidogrel

    In individuals aged 9-26, will increasing provider and parent education about the human papillomavirus (HPV) vaccine increase the rate of HPV Vaccination

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    Background: HPV is the most common sexually transmitted infection (STI) affecting millions of individuals in the United States (US). Since the introduction of the HPV vaccine, infections have declined. Yet, many adolescents remain unvaccinated.1 This review analyses the vital role of provider and patient education in increasing the rate of HPV vaccination, and what strategies can be implemented to improve HPV vaccine coverage. Purpose: The purpose of this review is to describe the factors that affect HPV vaccination numbers and how to increase HPV vaccination rates. In individuals aged 9-26, will increasing provider and parent education about the HPV vaccine, compared to current practice, increase the rate of HPV vaccination? Methods: Search engines included PubMed, Jamanetwork, and the CDC using the search terms: human papillomavirus, HPV, HPV vaccination, HPV epidemiology, HPV provider education, HPV patient education, HPV trends, and increasing HPV vaccination. Inclusion criteria were studies that were published in 2017 or later, original research, and free full text. Exclusion criteria were studies that were published before 2017 and systemic reviews. Conclusions: Increasing both provider and patient knowledge about the HPV vaccine will increase the vaccination rate. Strategies include HPV continuing education for providers, HPV health campaigns, and increasing access to Vaccine for Children (VFC) providers. More studies are needed to target the lower vaccination rates in non-Hispanic Whites and in adolescents with mothers with higher education

    What Are Barriers and Contributing Factors Limiting Healthcare Access in Southern Africa?

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    Introduction: Equitable access to timely and basic health care is an intrinsic component of overall equity in health and lack of it may be both an indicator and “contributory cause” of a population’s health inequalities, especially in developing countries.1 Therefore it is important to find the root causes that are causing the barriers and those contributing to people not being able to access healthcare when they need it and in a timely manner. Purpose: The purpose of the study is to review barriers and contributing factors that are limiting access to healthcare in Southern Africa. Methods: A comprehensive literature review was conducted using MEDLINE, Google Scholar, PubMed, and the Lindell Library using the search terms healthcare access in southern Africa/Africa, barriers to healthcare in Southern Africa/Africa. Inclusion criteria were studies from 2015 to present and exclusion criteria were studies that were older than 2015. Conclusions: In Southern Africa, socioeconomic factors, stigma, disabilities and transport, all pose barriers to timely access of healthcare

    Can Exercise be an Alternative Treatment Option for Depression

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    As most people know, exercise has always been beneficial for our overall health. No matter which exercise program it is, they all provide some sort of benefit. A growing problem has been depression as more and more people are being diagnosed. Since normally, most people would be prescribed SSRIs, I wanted to find out if there were alternative options. I sought to determine if exercise can be an alternative treatment option for depression. A comprehensive literature review was conducted using the websites PubMed, NCBI, Science Direct, & Academic Search Premier and using the search terms depression, anxiety, exercise, yoga, resistance training, cardiovascular training, and males vs females. Inclusion criteria were studies that had specific exercise programs for different groups and measured their depression or depressive symptoms. Exclusion criteria were studies that did not have a specific exercise program to their study or if the study was not measuring depressive symptoms. Specific exercise programs are a beneficial treatment option for depression. Cardiovascular exercise is the most useful in the treatment of depression. Other forms of exercise include yoga and aquatic exercise which also improve depression symptoms. Resistance training has been contradicting and cannot be proven as an alternative treatment option at this time. An implication for further work will be determining how these different forms of exercise work long-term in a younger population of individuals

    A Role for COX Inhibition in the Prevention of Progression of Barrett’s Esophagus To Esophageal Adenocarcinoma

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    Background: Barrett’s esophagus is the most significant predictor of the development of esophageal adenocarcinoma. The current treatment recommendation is a proton pump inhibitor to control acid reflux, yet there remains a significant number of individuals who progress to cancer. More can be done to prevent this progression. Purpose: To this end, this paper seeks to answer the following PICO question: P: Patients with Barrett’s esophagus not yet esophageal adenocarcinoma; I: Standard PPI treatment with the addition of Aspirin; C: Standard PPI treatment only; O: Prevention of progression of Barrett’s esophagus to esophageal adenocarcinoma. Methods: A comprehensive literature review was conducted using PubMed, Sage Journals, and Science Direct using the search terms Barrett’s esophagus treatment, Barrett’s esophagus aspirin, esophageal cancer prevention aspirin, cancer prevention aspirin, and prostaglandin cancer. Inclusion criteria were peer-reviewed, scholarly journals and studies published during or after 2017. Excluded from the search were meta-analyses and reviews. Conclusions: Aspirin shows promise as a possible adjunctive treatment to proton pump inhibitors. A long-term study is needed to specifically assess if adding aspirin will reduce progression to adenocarcinoma while also assessing safety. Several biomarkers and tissue pathologies are already available to risk stratify who could benefit from this add-on treatment

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