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Alışveriş Yolculuklarında Temas Edilen Kanalların Kişiselleştirilmiş Müşteri Deneyimlerine Etkisi
Teknolojinin hızla gelişimini sürdürmesi ile alışveriş deneyimleri gelenekselden dijitale evirilmiştir. Dijital kanalların çeşitlenmesi sonucunda dijital ve fiziksel kanalların bir arada kullanımıyla temas noktası sayısındaki artış müşterilere kendi satın alma yolculuklarını tasarlama imkanı sunmaktadır. Müşteri yolculuğu satın alma öncesi, satın alma ve satın alma sonrası aşamaları barındıran bir süreçtir. Günümüz müşterileri her aşamada kanallar arasında akıcı deneyimler yaşamayı tercih etmektedirler. Bu sebeple firmaların kullanılan kanalları, temas noktalarını genel anlamıyla müşteri yolculuklarını iyi analiz etmesi gerekmektedir. Bu araştırma ile müşterilerin gözünden alışveriş yolculuklarını nasıl tasarladıkları ve bu süreçte yaşadıkları deneyimler incelenerek birbirlerinden farklılaştıkları yönlerini analiz etmeyi hedeflemektedir. Araştırmada sıralı karma yöntem kullanılmış, veri toplama aracı olarak ilk bölümde iki aşamadan oluşan bir çevrim içi anket çalışmasından yararlanılmış, anket 385 katılımcıya uygulanmıştır. Anket sonucunda gönüllü olarak katılım sağlayacak 30 kişi belirlenerek yarı yapılandırılmış görüşmeler ve müşteri yolculuğu haritası kullanılarak bilgi toplanmıştır. Toplanan verilerin sonucunda elde edilen müşteri yolculukları sektörlere göre sınıflandırılarak temas noktası, kanal ve etkileyici faktörler ışığında karşılaştırılmışlardır. Katılımcıların büyük çoğunluğunun alışveriş yolculuklarında bütünleşik kanal anlayışının sunduğu imkanlara ihtiyaç duyduğu gözlenmiştir. Müşteri yolculukları fiziksel ve dijital bağlamlarda temas ettikleri kanallar, sosyal deneyimleri ve sağladıkları faydalara göre benzerlik göstermektedirler. İncelemeler sonucunda müşteri yolculuklarının birebir aynı olmadığı gözlemlenmiştir, kanal geçişleri, ulaşılan sonuç ürün, satın almaya etki eden faktörler ile her müşteri yolculuğunun özgün olduğu görülmektedir.As technology continues to evolve rapidly, shopping experiences have evolved from traditional to digital. As a result of the diversification of digital channels, the increase in the number of contact points with the use of digital and physical channels together offers customers the opportunity to design their purchasing journeys. The customer journey is a process that includes pre-purchase, purchase, and post-purchase stages. Today's customers prefer to have smooth experiences across channels at every stage. For this reason, companies need to analyze the channels used, contact points, and customer journeys in general terms. This research aims to analyze how they design their shopping journey from the eyes of customers and their experiences in this process and analyze the aspects in which they differ from each other. The sequential mixed method was used in the research, an online questionnaire consisting of two stages was used as a data collection tool in the first part, and the questionnaire was applied to 385 participants. As a result of the survey, 30 people who will participate voluntarily were determined and information was gathered using semi-structured interviews and a customer journey map. The customer journeys obtained because of the collected data were classified according to sectors and compared in the light of contact points, channels, and influencing factors. It was observed that most of the participants needed the opportunities offered by the integrated channel understanding in their shopping journeys. Customer journeys are similar in physical and digital contexts according to the channels they contact with, their social experiences, and the benefits they provide. As a result of the examinations, it has been observed that the customer journeys are not the same, it is seen that each customer journey is unique with the channel transitions, the resulting product, and the factors affecting the purchase
Platelet to Lymphocyte Ratıo in Respıratory Syncytıal Vırus Infectıon
Respiratory syncytial virus (RSV) is a viral pathogen that causes respiratory system infections in childhood. In this study, we aim to examine the role of Platelet to lymphocyte ratio (PLR) and Platelet to Lymphocyte and monocyte ratio (PLT/LY+MO) values in the prediction of RSV infection and in the differentiation of upper and lower respiratory tract RSV infections. Complete blood counts and RSV Antigen test results of 76 patients, between the age of 0 and 12 were investigated retrospectively. PLR values are calculated using Platelet Count/Lymphocyte Count formula, whereas PLMR values are calculated using Platelet Count/Lymphocyte Count+Monocyte Count. Out of 76, 32 patients were diagnosed as having RSV infection due to RSV antigen test. The percentage lymphocyte and monocyte as well as the platelet count were significantly higher in RSV positive group. Monocyte percentage in lower respiratory tract RSV infection was significantly lower compared to upper respiratory tract RSV infection. Our study revealed that blood parameters like lymphocyte and monocyte percentage and platelet count may be an important clue for the clinician for RSV infection and also, play a role as a guide before advanced techniques. In addition, percentage of monocyte can be useful to detect the lower respiratory tract involvement in RSV infection.Respiratuar sinsityal virüs (RSV), çocukluk çağında solunum sistemi enfeksiyonlarına neden olan viral bir patojendir. Bu çalışmada Trombosit/lenfosit oranı (PLR) ve Platelet/Lenfosit oranının (PLT/LY+MO) RSV enfeksiyonunun ön tanısında ve üst-alt solunum yolu RSV indfeksiyonlarının ayrımındaki rolünü incelemeyi amaçladık. 0-12 yaş arası 76 hastanın tam kan sayımı ve RSV Antijen test sonuçları geriye dönük olarak incelenmiştir. PLR değerleri Trombosit Sayısı/Lenfosit Sayısı formülü kullanılarak hesaplanırken, PLMR değerleri Trombosit Sayısı/Lenfosit Sayısı+Monosit Sayısı kullanılarak hesaplanmıştır. RSV antijen test sonuçlarına göre 76 hastanın 32'sine RSV enfeksiyonu teşhisi konmuştur. RSV pozitif grupta lenfosit ve monosit yüzdesi ile trombosit sayısı anlamlı derecede yüksek bulunmuştur. Alt solunum yolu RSV enfeksiyonunda monosit yüzdesinin ise üst solunum yolu RSV enfeksiyonuna göre anlamlı derecede düşük olduğu saptanmıştır. Çalışmamız lenfosit ve monosit yüzdesi ile trombosit sayısı gibi kan parametrelerinin RSV enfeksiyonu için klinisyene bir ipucu verebileceğini ve ayrıca ileri teknikler öncesinde yol gösterici rol oynayabileceğini ortaya koymuştur. Ek olarak, monosit yüzdesinin, RSV enfeksiyonunda alt solunum yolu tutulumunu saptamak için faydalı olabileceği sonucuna varılmıştır
Measurements of the Suppression and Correlations of Dijets in Pb Plus Pb Collisions at √snn=5.02 Tev
Studies of the correlations of the two highest transverse momentum (leading) jets in individual Pb+Pb colli-sion events can provide information about the mechanism of jet quenching by the hot and dense matter created in such collisions. In Pb+Pb and pp collisions at root NN = 5.02 TeV, measurements of the leading dijet transverse momentum (pT) correlations are presented. Additionally, measurements in Pb+Pb collisions of the dijet pair nuclear modification factors projected along leading and subleading jet pT are made. The measurements are per-formed using the ATLAS detector at the LHC with 260 pb(-1) of pp data collected in 2017 and 2.2 nb(-1) of Pb+Pb data collected in 2015 and 2018. An unfolding procedure is applied to the two-dimensional leading and sublead-ing jet pT distributions to account for experimental effects in the measurement of both jets. Results are provided for dijets with leading jet pT greater than 100 GeV. Measurements of the dijet-yield-normalized xJ distributions in Pb+Pb collisions show an increased fraction of imbalanced jets compared to pp collisions; these measurements are in agreement with previous measurements of the same quantity at 2.76 TeV in the overlapping kinematic range. Measurements of the absolutely normalized dijet rate in Pb+Pb and pp collisions are also presented, and show that balanced dijets are significantly more suppressed than imbalanced dijets in Pb+Pb collisions. It is observed in the measurements of the pair nuclear modification factors that the subleading jets are significantly suppressed relative to leading jets with pT between 100 and 316 GeV for all centralities in Pb+Pb collisions.ANPCyT, Argentina; YerPhI, Armenia; ARC, Australia; BMWFW, Austria; FWF, Austria; ANAS, Azerbaijan; CNPq, Brazil; FAPESP, Brazil; NSERC, Canada; NRC, Canada; CFI, Canada; CERN; ANID, Chile; CAS, China; MOST, China; NSFC, China; Minciencias, Colombia; MEYS CR, Czech Republic; DNRF, Denmark; DNSRC, Denmark; IN2P3-CNRS, France; CEA-DRF/IRFU, France; SRNSFG, Georgia; BMBF, Germany; HGF, Germany; MPG, Germany; GSRI, Greece; RGC, China; Hong Kong SAR, China; ISF, Israel; Benoziyo Center, Israel; INFN, Italy; MEXT, Japan; JSPS, Japan; CNRST, Morocco; NWO, Netherlands; RCN, Norway; MEiN, Poland; FCT, Portugal; MNE/IFA, Romania; MESTD, Serbia; MSSR, Slovakia; ARRS, Slovenia; MIZS, Slovenia; DSI/NRF, South Africa; MICINN, Spain; SRC, Sweden; Wallenberg Foundation, Sweden; SERI, Switzerland; SNSF, Switzerland; Canton of Bern, Switzerland; Canton of Geneva, Switzerland; MOST, Taiwan; TENMAK, Turkiye; STFC, United Kingdom; DOE, United States of America; NSF, United States of America; BCKDF, Canada; CANARIE, Canada; Compute Canada, Canada; CRC, Canada; PRIMUS, Czech Republic [21/SCI/017]; UNCE, Czech Republic [SCI/013]; COST, European Union; ERC, European Union; ERDF, European Union; Horizon 2020, European Union; Marie Sklodowska-Curie Actions, European Union; Investissements d'Avenir Labex, France; Investissements d'Avenir Idex, France; ANR, France; DFG, Germany; AvH Foundation, Germany; Herakleitos program - EU-ESF, Greece; Thales program - EU-ESF, Greece; Aristeia program - EU-ESF, Greece; Greek NSRF, Greece; BSF-NSF, Israel; MINERVA, Israel; Norwegian Financial Mechanism 2014-2021, Norway; NCN, Poland; NAWA, Poland; La Caixa Banking Foundation, Spain; CERCA Programme Generalitat de Catalunya, Spain; PROMETEO Programme Generalitat Valenciana, Spain; GenT Programme Generalitat Valenciana, Spain; Goran Gustafssons Stiftelse, Sweden; Royal Society, United Kingdom; Leverhulme Trust, United KingdomWe thank CERN for the very successful operation of the LHC, as well as the support staff from our institutions without whom ATLAS could not be operated efficiently. We acknowledge the support of ANPCyT, Argentina; YerPhI, Armenia; ARC, Australia; BMWFW and FWF, Austria; ANAS, Azerbaijan; CNPq and FAPESP, Brazil; NSERC, NRC, and CFI, Canada; CERN; ANID, Chile; CAS, MOST, and NSFC, China; Minciencias, Colombia; MEYS CR, Czech Republic; DNRF and DNSRC, Denmark; IN2P3-CNRS and CEA-DRF/IRFU, France; SRNSFG, Georgia; BMBF, HGF, and MPG, Germany; GSRI, Greece; RGC and Hong Kong SAR, China; ISF and Benoziyo Center, Israel; INFN, Italy; MEXT and JSPS, Japan; CNRST, Morocco; NWO, Netherlands; RCN, Norway; MEiN, Poland; FCT, Portugal; MNE/IFA, Romania; MESTD, Serbia; MSSR, Slovakia; ARRS and MIZS, Slovenia; DSI/NRF, South Africa; MICINN, Spain; SRC and Wallenberg Foundation, Sweden; SERI, SNSF, and Cantons of Bern and Geneva, Switzerland; MOST, Taiwan; TENMAK, Turkiye; STFC, United Kingdom; DOE and NSF, United States of America. In addition, individual groups and members have received support from BCKDF, CANARIE, Compute Canada, and CRC, Canada; PRIMUS 21/SCI/017 and UNCE SCI/013, Czech Republic; COST, ERC, ERDF, Horizon 2020, and Marie Sklodowska-Curie Actions, European Union; Investissements d'Avenir Labex, Investissements d'Avenir Idex, and ANR, France; DFG and AvH Foundation, Germany; Herakleitos, Thales, and Aristeia programs co-financed by EU-ESF and the Greek NSRF, Greece; BSF-NSF and MINERVA, Israel; Norwegian Financial Mechanism 2014-2021, Norway; NCN and NAWA, Poland; La Caixa Banking Foundation, CERCA Programme Generalitat de Catalunya, and PROMETEO and GenT Programmes Generalitat Valenciana, Spain; Goran Gustafssons Stiftelse, Sweden; The Royal Society and Leverhulme Trust, United Kingdom. The crucial computing support from all WLCG partners is acknowledged gratefully, in particular from CERN, the ATLAS Tier-1 facilities at TRIUMF (Canada), NDGF (Denmark, Norway, Sweden), CC-IN2P3 (France), KIT/GridKA (Germany), INFN-CNAF (Italy), NL-T1 (Netherlands), PIC (Spain), ASGC (Taiwan), RAL (UK), and BNL (USA), the Tier-2 facilities worldwide, and large non-WLCG resource providers. Major contributors of computing resources are listed in Ref. [45]
Track While Scan Radar Design and Simulation
13th International Symposium on Advanced Topics in Electrical Engineering, ATEE 2023 -- 23 March 2023 through 25 March 2023 -- 188327Track While Scan (TWS) radars are generally used in military systems, constantly monitoring the positions of the target and generating data about it. They measure a target's coordinates, determine its trajectory, and predict its next location. They can usually track a single target but do so with very high sensitivity. "TWS Radar"is often used as a "Fire Control Radar"in the armed forces. This study addresses the design of a TWS radar with MATLAB programming language. The operation of this radar was simulated, and targets were detected using matched filter in MATLAB. Transmitted and received signal parameters are explained. A MATLAB algorithm which generates the transmitted and the received pulses for single Pulse Repetition Interval (PRI) was written in the first step. Match filtering was implemented for detecting targets. A fixed threshold value is defined, and position of the targets are reported with MATLAB algorithm. A white Gaussian noise was added to the output of the matched filter and targets are reported for the same threshold value. Radar was tested under the different Signal to Noise Ratio (SNR) rates. The scope view of the TWS Radar was plotted for 2 degrees antenna beam width for different SNR values. © 2023 IEEE
Relapsing-remitting Multipl Sklerozda Clusterin Genetik Polimorfizmleri ve Dolaşımdaki Mikrorna'ların Plazma Clusterin Seviyesi ve Bilişsel Performans Üzerine Etkilerinin İncelenmesi
Multipl Skleroz (MS), merkezi sinir sisteminin demiyelinizan, otoimmün ve nörodejeneratif kronik bir hastalığıdır. Etiyolojisinde genetik ve çevresel faktörlerin kompleks etkileşimlerinin rol oynadığı MS'in en yaygın klinik formu RRMS'tir. MS'te, progresyonun bir göstergesi olan bilişsel bozukluğun prevelansı %40-70 arasındadır. Clusterin, hücresel yaşam ve ölüm yolaklarında aktif rol oynamaktadır. Bu proteini kodlayan CLU geninde bulunan tek nükleotit polimorfizmleri (SNP) birçok hastalıkla ilişkili bulunmuş olup clusterinin dolaşımdaki seviyelerinin bilişsel performansla ilişkili olduğuna dair bulgular literatürde mevcuttur. Gen ifadesinin düzenlenmesinde rol alan mikroRNA'lar (miRNA) birçok hastalığın teşhisi ve seyri ile ilişkilendirilmiş olup biyobelirteç keşif çalışmalarının önemli odaklarındandır. Bu tez çalışması kapsamında RRMS riski ile CLU rs11136000 C/T, rs3087554 T/C, rs2279590 C/T ve rs1532278 C/T SNP'lerinin ilişkilerinin incelenmesi ve plazma clusterin konsantrasyonu ile CLU ekspresyon seviyesine etki ettiği bilinen miR-21-5p ve miR-195-5p'nin plazma rölatif ekspresyon seviyelerinin hastalık riski ve bilişsel bozukluk ile ilişkilerinin belirlenmesi amaçlanmıştır. Bu amaç doğrultusunda iki çalışma grubu oluşturulmuştur. Grup-1, 310 RRMS hastası ve 310 kontrol bireyden oluşurken Grup-2, 30 naif RRMS hastası, 30 tedavi alan RRMS hastası ve 30 kontrol bireyden oluşmaktadır. Grup-1'deki RRMS hastalarının genotiplemeleri PCR-RFLP ve RT-PCR ile gerçekleştirilmiştir. Grup-2'deki katılımcıların bilişsel değerlendirilmeleri BICAMS bataryası ile gerçekleştirilmiştir. Grup-2 katılımcılarının plazma miR-21-5p ve miR-195-5p ekspresyon seviyeleri qRT-PCR ile; plazma clusterin konsantrasyonu ise ELISA ile belirlenmiştir. Tüm örnekler Ankara Şehir Hastanesi Nöroloji Polikliniği'nden alınmıştır. Bu tez çalışmasında rs3087554 T/C SNP'sinin C alelinin hem RRMS riski hem RRMS progresyonu ile ilişkili olduğu görülmüştür. RRMS ile ilişkileri incelenen miR-21-5p ve miR-195-5p'nin plazma rölatif ekspresyon seviyelerinin RRMS teşhisi için biyobelirteç olabilecekleri görülmüştür. Ayrıca, miR-21-5p'nin potansiyel bir terapötik biyobelirteç olabileceğine dair bulgulara ulaşılmıştır. Buna ilave olarak, hem miR-21-5p'nin hem de miR-195-5p'nin MS'te kullanılan enjektabl immünomodülatör tedavilerin terapötik hedefi olabileceği düşünülmektedir. Bu tez çalışmasıyla birlikte clusterinin MS'teki rolü genotip, fenotip ve bilişsel seviyede değerlendirilmiştir. CLU rs11136000 C/T, rs3087554 T/C, rs2279590 C/T ve rs1532278 C/T SNP'leri ile RRMS riski arasındaki ilişki ilk defa bu tezde çalışılmıştır. Ayrıca, bu çalışmada ilk defa RRMS hastalarının plazma clusterin seviyesi, plazma miR-21-5p ve miR-195-5p rölatif ekspresyon seviyesi ile bilişsel performansları arasındaki ilişkiler incelenmiştir. RRMS'in teşhisi ve prognozunun takibi için plazmadaki potansiyel biyobelirteç adaylarını ortaya koyan bu çalışmanın geliştirilecek biyosensörlere, tedavi ajanlarına ve tanı kitlerine yol göstereceği öngörülmektedir. Multidisipliner bir yaklaşımın ürünü olan bu tez, bahsi geçen yönleriyle Biyomedikal Mühendisliği alanına katkı sağlayan bir çalışma niteliğindedir.Multiple Sclerosis (MS) is a demyelinating, autoimmune, and neurodegenerative chronic disease of the central nervous system. Complex interactions of genetic and environmental factors play an important role in the etiology of MS, the most common clinical form of which is relapsing-remitting MS (RRMS). The prevalence of cognitive impairment, an indicator of progression in MS, ranges from 40% to 70%. Clusterin plays a major role in cell survival and cell death pathways. Single nucleotide polymorphisms (SNP's) in the CLU gene, which encodes clusterin protein, have been associated with many diseases, and there is evidence in the literature suggesting an association between clusterin level in circulation and cognitive performance. MicroRNAs involved in the regulation of gene expression have been associated with the diagnosis and progression of many diseases and they are important foci of biomarker discovery studies. In this thesis, the aim was to investigate the relationships between RRMS risk and the CLU rs11136000 C/T, rs3087554 T/C, rs2279590 C/T, and rs1532278 C/T SNPs, as well as to determine the associations between plasma levels of clusterin and plasma relative expression levels of miR-21-5p and miR-195-5p, which are known to target CLU gene, with disease risk and cognitive impairment. For this purpose, there are two study groups: Group-1 consisted of 310 RRMS patients and 310 healthy controls, while Group-2 consisted of 30 treatment-naïve RRMS patients, 30 injectable disease modifying therapy (DMT)-receiving RRMS patients, and 30 healthy controls. Genotypes of RRMS patients in Group-1 were determined by PCR-RFLP and RT-PCR. Cognitive evaluations of participants in Group-2 were carried out by applying the BICAMS test battery. Plasma relative expressions levels of miR-21-5p and miR-195-5p were determined by qRT-PCR, and plasma clusterin concentrations were analyzed with ELISA. The samples were collected from Ankara City Hospital Neurology Clinic. In this thesis, it was observed that the C allele of the rs3087554 T/C is associated with both RRMS risk and progression. The plasma relative expression levels of miR-21-5p and miR-195-5p were found to have the potential to be biomarkers for the diagnosis of RRMS. Moreover, the findings suggested that miR-21-5p could be a potential therapeutic biomarker. In addition, both miR-21-5p and miR-195-5p are thought to be therapeutic targets of injectable DMT's used in MS. With this thesis, the role of clusterin in MS was evaluated at genotype, phenotype, and cognitive level. The relationship between rs11136000 C/T, rs3087554 T/C, rs2279590 C/T, rs1532278 C/T SNP's, and RRMS risk was investigated for the first time in this thesis. In addition, for the first time in this study, the relationships between plasma clusterin levels, plasma miR-21-5p and miR-195-5p relative expression levels, and cognitive performance of RRMS patients were investigated. With this study, which identifies potential biomarker candidates in plasma for the diagnosis and prognosis of RRMS, will guide the development of biosensors, therapeutic agents, and diagnostic kits. This thesis, which is a product of a multidisciplinary approach, is a study contributing to the field of Biomedical Engineering in the aforementioned aspects
Investigation the Ergodic Distribution of a Semi-Markovian Inventory Model of Type (s,s) With Intuitive Approximation Approach
This paper concerns a stochastic process expressing (s,S) type inventory system with intuitive approximation approach. The stock level in the system is modeled as a semi-Markovian renewal reward process X(t). Therefore, the ergodic distributions of this process can be analyzed with the help of the renewal function. Obtaining explicit formula for renewal function U(x) is difficult from a practical standpoint. Mitov and Omey recently present some intuitive approximations in literature for renewal function which cover a large number of existing results. Using their approach we were able to establish asymptotic approximations for ergodic distribution of a stochastic process X(t). Obtained results can be used in many situations where demand random variables have different distributions from different classes such as Γ(g) class
Osmanlı Rumelisinde Türkçenin Gelişimine Katkı Sağlayan Eşraf Aileleri
Osmanlı sanatı ve himaye ilişkisi bir arada değerlendirildiğinde bu ilişkiyi üst düzeyde temsil etme, yönetme, yönlendirme vb. hususlarda sarayın desteği ve etkisinin ilk sırada anılması yanında önemli devlet görevlerinde bulunan isimlerin de zikredildiği görülür. Bu isimlerin büyük bölümü Osmanlı’nın önemli ailelerine mensuptur. Bu bildiride Osmanlıda benzer konumda bir ailenin parçası olarak himaye faaliyetleri içerisinde yer alan önemli Arnavut ailelerine mensup isimler hami vasıflarıyla ele alınacak, bu isimlerin çok görünür olmasa da bulundukları coğrafyalarda Osmanlı kültür ve sanatına ne ölçüde katkı sağladıkları değerlendirilecektir. Yapılacak değerlendirme ile aynı zamanda şair ve hami olan bazı Osmanlı ailelerinin şiir piyasasında ne ölçüde gündemde oldukları da ortaya konmuş olacaktır. Bununla birlikte Osmanlı coğrafyasında saray ve devlet erkânı eliyle toplumun entelektüel kesiminin Türkçe şiire ilgisi de ortaya konmuş olacaktır.When the relationship between Ottoman art and patronage is evaluated together, it is necessary to represent, direct, direct, etc. this relationship at a high level. In addition to mentioning the support and influence of the palace in the first place, it is seen that the names who held important state duties are also mentioned. Most of these names belong to important families of the Ottoman Empire. In this paper, the names of important Albanian families, who are part of a family in a similar position in the Ottoman Empire, will be discussed with their patron qualities, and it will be evaluated to what extent these names contribute to the Ottoman culture and art in their geographies, even if they are not very visible. With the evaluation to be made, it will also be revealed to what extent some Ottoman families, who were poets and patrons, were on the agenda in the poetry market. In addition, the interest of the intellectual part of the society in Turkish poetry will be revealed by the court and state officials in the Ottoman geography
Search for Doubly Charged Higgs Boson Production in Multi-Lepton Final States Using 139 Fb-1 of Proton-Proton Collisions at √s=13 Tev With the Atlas Detector
A search for pair production of doubly charged Higgs bosons (H-+/-+/-), each decaying into a pair of prompt, isolated, and highly energetic leptons with the same electric charge, is presented. The search uses a proton-proton collision data sample at a centre-of-mass energy of 13 TeV corresponding to an integrated luminosity of 139 fb(-1) recorded by the ATLAS detector during Run 2 of the Large Hadron Collider (LHC). This analysis focuses on same-charge leptonic decays, H-+/-+/- -> l(+/-)l'(+/-) where l, l' = e, mu, tau, in two-, three-, and four-lepton channels, but only considers final states which include electrons or muons. No evidence of a signal is observed. Corresponding upper limits on the production cross-section of a doubly charged Higgs boson are derived, as a function of its mass m(H-+/-+/-), at 95% confidence level. Assuming that the branching ratios to each of the possible leptonic final states are equal, B(H-+/-+/- -> e(+/-)e(+/-)) = B(H-+/-+/- -> e(+/-)mu(+/-)) = B(H-+/-+/- -> mu(+/-)mu(+/-)) = B(H-+/-+/- -> e(+/-)tau(+/-)) = B(H-+/-+/- -> mu(+/-)tau(+/-)) = B(H-+/-+/- -> tau(+/-)tau(+/-)) = 1/6, the observed (expected) lower limit on the mass of a doubly charged Higgs boson is 1080GeV(1065 GeV) within the left-right symmetric type-II seesaw model, which is the strongest limit to date produced by the ATLAS Collaboration. Additionally, this paper provides the first direct test of the Zee-Babu neutrino mass model at the LHC, yielding an observed (expected) lower limit of m(H-+/-+/-) = 900 GeV (880 GeV).ANPCyT, Argentina; YerPhI, Armenia; ARC, Australia; BMWFW, Austria; FWF, Austria; ANAS, Azerbaijan; CNPq, Brazil; FAPESP, Brazil; NSERC, Canada; CFI, Canada; NSFC, China; MEYS CR, Czech Republic; DNRF, Denmark; DNSRC, Denmark; IN2P3-CNRS, France; CEA-DRF/IRFU, France; BMBF, Germany; MPG, Germany; Hong Kong SAR, China; ISF, Israel; INFN, Italy; MEXT, Japan; JSPS, Japan; CNRST, Morocco; RCN, Norway; MEiN, Poland; FCT, Portugal; MNE/IFA, Romania; MESTD, Serbia; MSSR, Slovakia; ARRS, Slovenia; MIZS, Slovenia; MICINN, Spain; Wallenberg Foundation, Sweden; SERI, Switzerland; MOST, Taiwan; DOE, United States of America; NSF, United States of America; BCKDF, Canada; CANARIE, Canada; Compute Canada, Canada; Czech Republic [PRIMUS 21/SCI/017, UNCE SCI/013]; COST, European Union; ERC, European Union; ERDF, European Union; Horizon 2020, European Union; Marie Skodowska-Curie Actions, European Union; Investissements d'Avenir Labex, France; Investissements d'Avenir Idex , France; ANR, France; DFG , Germany; AvH Foundation, Germany; Herakleitos programme - EU-ESF, Greece; Thales programme - EU-ESF, Greece; Aristeia programme - EU-ESF, Greece; Greek NSRF, Greece; BSF-NSF, Israel; MINERVA, Israel; Norwegian Financial Mechanism 2014-2021, Norway; NCN, Poland; NAWA, Poland; La Caixa Banking Foundation, Spain; CERCA Programme Generalitat de Catalunya, Spain; PROMETEO Programme Generalitat Valenciana, Spain; GenT Programme Generalitat Valenciana, Spain; Goran Gustafssons Stiftelse, Sweden; Royal Society, United Kingdom; Leverhulme Trust, United Kingdom; STFC, United Kingdom; TENMAK, Turkiye; Canton of Geneva, Switzerland; Canton of Bern, Switzerland; SNSF, Switzerland; SRC, Sweden; DSI/NRF, South Africa; NWO, Netherlands; Benoziyo Center, Israel; RGC, China; GSRI, Greece; HGF, Germany; SRNSFG, Georgia; Minciencias, Colombia; MOST, China; CAS, China; ANID, Chile; CERN; NRC, CanadaWe thank CERN for the very successful operation of the LHC, as well as the support staff from our institutions without whom ATLAS could not be operated efficiently. We acknowledge the support of ANPCyT, Argentina; YerPhI, Armenia; ARC, Australia; BMWFW and FWF, Austria; ANAS, Azerbaijan; CNPq and FAPESP, Brazil; NSERC, NRC and CFI, Canada; CERN; ANID, Chile; CAS, MOST and NSFC, China; Minciencias, Colombia; MEYS CR, Czech Republic; DNRF and DNSRC, Denmark; IN2P3-CNRS and CEA-DRF/IRFU, France; SRNSFG, Georgia; BMBF, HGF and MPG, Germany; GSRI, Greece; RGC and Hong Kong SAR, China; ISF and Benoziyo Center, Israel; INFN, Italy; MEXT and JSPS, Japan; CNRST, Morocco; NWO, Netherlands; RCN, Norway; MEiN, Poland; FCT, Portugal; MNE/IFA, Romania; MESTD, Serbia; MSSR, Slovakia; ARRS and MIZS, Slovenia; DSI/NRF, South Africa; MICINN, Spain; SRC and Wallenberg Foundation, Sweden; SERI, SNSF and Cantons of Bern and Geneva, Switzerland; MOST, Taiwan; TENMAK, Turkiye; STFC, United Kingdom; DOE and NSF, United States of America. In addition, individual groups and members have received support from BCKDF, CANARIE, Compute Canada and CRC, Canada; PRIMUS 21/SCI/017 and UNCE SCI/013, Czech Republic; COST, ERC, ERDF, Horizon 2020 and Marie Skodowska-Curie Actions, European Union; Investissements d'Avenir Labex, Investissements d'Avenir Idex and ANR, France; DFG and AvH Foundation, Germany; Herakleitos, Thales and Aristeia programmes co-financed by EU-ESF and the Greek NSRF, Greece; BSF-NSF and MINERVA, Israel; Norwegian Financial Mechanism 2014-2021, Norway; NCN and NAWA, Poland; La Caixa Banking Foundation, CERCA Programme Generalitat de Catalunya and PROMETEO and GenT Programmes Generalitat Valenciana, Spain; Goran Gustafssons Stiftelse, Sweden; The Royal Society and Leverhulme Trust, United Kingdom. The crucial computing support from all WLCG partners is acknowledged gratefully, in particular from CERN, the ATLAS Tier-1 facilities at TRIUMF (Canada), NDGF (Denmark, Norway, Sweden), CC-IN2P3 (France), KIT/GridKA (Germany), INFN-CNAF (Italy), NL-T1 (Netherlands), PIC (Spain), ASGC (Taiwan), RAL (UK) and BNL (USA), the Tier-2 facilities worldwide and large non-WLCG resource providers. Major contributors of computing resources are listed in Ref. [96
Measurement of the Sensitivity of Two-Particle Correlations in Pp Collisions To the Presence of Hard Scatterings
A key open question in the study of multiparticle production in high-energy pp collisions is the relationship between the "ridge"-i.e., the observed azimuthal correlations between particles in the underlying event that extend over all rapidities-and hard or semihard scattering processes. In particular, it is not known whether jets or their soft fragments are correlated with particles in the underlying event. To address this question, two-particle correlations are measured in pp collisions at sqrt[s]=13 TeV using data collected by the ATLAS experiment at the LHC, with an integrated luminosity of 15.8 pb^{-1}, in two different configurations. In the first case, charged particles associated with jets are excluded from the correlation analysis, while in the second case, correlations are measured between particles within jets and charged particles from the underlying event. Second-order flow coefficients, v_{2}, are presented as a function of event multiplicity and transverse momentum. These measurements show that excluding particles associated with jets does not affect the measured correlations. Moreover, particles associated with jets do not exhibit any significant azimuthal correlations with the underlying event, ruling out hard processes contributing to the ridge
A Unique Case of Isolated Thoracic Spinal Rosai-Dorfman Disease Related To Igg4
Rosai-Dorfman disease (RDD) is a rare benign histiocytosis usually characterized by massive cervical lymphadenopathy and systemic manifestations. Extranodal, especially spinal involvement, is extremely rare. Our case was deemed worthy of presentation because it was the first reported isolated case of spinal RDD related to IgG4 and mimicked meningioma clinically and radiologically. A case with an intradural extramedullary mass causing neurological compression findings in the thoracic spinal region and radiologically mimicking meningioma is presented. In the histomorphological examination of the resection material, polymorphonuclear leukocytes in the dura, histiocytes showing emperipolesis, an increase in collagenized fibrous connective tissue, and intense lymphoplasmacytic cell infiltration accompanied by obliterative phlebitis were observed. Immunohistochemically, the histiocytic cells were found to be S-100 protein, CD68, and CD163 positive and CD1a and langerin negative, and more than half of the plasma cells were immunoglobulin-G4 (IgG4) positive. Although rare, RDD or IgG4-related meningeal disease should be considered in the differential diagnosis of dural-based spinal masses that radiologically suggest meningioma. The pathologist should be aware that these two histopathological entities may coexist. To our knowledge, this is the first case of isolated spinal RDD related to IgG4 reported in the literature