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    461 research outputs found

    Architecture of active extensional faults in carbonates: Campo Felice and Monte D’Ocre Faults, Italian Apennines

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    Structural field data relative to the fault/fracture network distribution collected in the footwall of the Campo Felice and Mt. D'Ocre damage zone

    EVs from hypoxic NB cells stimulate migration and invasion of target cells via miR-210-3p

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    Tumor hypoxia stimulates release of extracellular vesicles (EVs) that facilitate short- and long-range intercellular communication and metastatization. Albeit hypoxia and EVs release are known features of Neuroblastoma (NB), a metastasis-prone childhood malignancy of the sympathetic nervous system, whether hypoxic EVs can facilitate NB dissemination is unclear. Here we show that EVs from hypoxic NB cells promote pro-metastasis features in vitro and in an in vivo model. EVs from NB cells cultured at different oxygen tensions did not differ for type and abundance of surface markers and for biophysical properties. However, EVs derived from hypoxic NB cells were more potent than their normoxic counterpart in inducing NB cells migration and colony formation. We characterized and compared the microRNA (miRNA) cargo of EVs from NB cells cultured at different oxygen tensions and found that miR-210-3p was the most upregulated. Mechanistically, we identified that the pro-metastatic features of EVs from hypoxic NB cells derived from a miR-210-3p enrichment in their cargo. Indeed, overexpression of miR-210-3p in normoxic EVs conferred them pro-metastatic features, whereas miR-210-3p silencing suppressed the metastatic ability of hypoxic EVs both in vitro and in in vivo zebrafish model. Our data identify a role for hypoxic EVs in the cellular and microenvironmental changes favoring NB dissemination

    Full-mechanized CTL production data in Scots pine forest in Poland

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    Dataset related to two harvesters and two forwarders machine working in Scots pine forest in Poland. the dataset consider a period of 18 months including machine engine parameters, STANFORD data and forest stand information. Data were acquired in the frame of CARE4C - Carbon smart forestry under climate change - H2020-MSCA-RISE-2017 Grant Agreement Number 778322

    Perfluoroalkyl Acids are Common Environmental Pollutants That Potently Stimulate Aldosterone Biosynthesis

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    Supplemental data (Perfluoroalkyl Acids are Common Environmental Pollutants That Potently Stimulate Aldosterone Biosynthesis

    Aldosterone Biosynthesis is Potently Stimulated by the Common Environmental Pollutants Perfluoroalkyl Acids

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    Supplemental data (Aldosterone Biosynthesis is Potently Stimulated by the Common Environmental Pollutants Perfluoroalkyl Acids

    Data from: Lung vascular-epithelial changes in patients undergoing tumour resection after SARS-CoV-2 infection: a retrospective comparative study

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    Data from: Lung vascular-epithelial changes in patients undergoing tumour resection after SARS-CoV-2 infection: a retrospective comparative stud

    Piante (stato fatto e ricostruzione) - Scavo archeologico Fondi Cossar Aquileia - 2009-2015 - Unipd

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    Il dataset raccoglie tutte le piante (stato di fatto delle evidenze stratigrafiche e ricostruzioni) relative allo scavo condotto presso i fondi Cossar di Aquileia dall'Università di Padova, la Soprintendenza del Friuli Venezia-Giulia e la Fondazione Aquilei

    Tabelle crono-tipologiche dei contesti - Scavo archeologico Fondi Cossar - Aquileia - 2009-2015 - Unipd

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    Il dataset raccoglie tutte le tabelle crono-tipologiche dei reperti recuperati nei contesti stratigrafici dello scavo condotto presso i fondi Cossar di Aquileia dall'Università di Padova, la Soprintendenza del Friuli Venezia-Giulia e la Fondazione Aquilei

    Analysis of Organic Matter Decomposition in the Salt Marshes of the Venice Lagoon (Italy) Using Standard Litter Bags

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    Dataset for the Analysis of Organic Matter Decomposition in the Salt Marshes of the Venice Lagoon (Italy) Using Standard Litter Bag

    Elastic parameters of kyanite

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    The file contains elastic parameters of kyanite. (Article title: Toward a Robust Elastic Geobarometry of Kyanite Inclusions in Eclogitic Diamonds

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