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Language and Sleep interactions in Infancy
Day and night patterns of sleep and vocabulary development in 5-24months-old infant
Dataset of the Doctoral Dissertation “The Energy to Come: Promises, Imaginaries and Ecology of Nuclear Fusion”
Dataset of the Doctoral Dissertation “The Energy to Come: Promises, Imaginaries and Ecology of Nuclear Fusion” by Alessio Giacometti, PhD in Social Sciences [37th Cycle, 2021/2024] at the University of Padova (Italy
Meso–Cenozoic geodynamic evolution of the Patagonian foreland: insights from low-temperature thermochronology in the Deseado Massif
Thermal modelling input data and results on Meso–Cenozoic geodynamic evolution of the Patagonian forelan
Prevalence of metabolic-associated fatty liver disease in patients with primary aldosteronism
Objective: to assess the prevalence of metabolic associated fatty liver disease (MAFLD) in patients with primary aldosteronism (PA) compared to other benign adrenal nodules, and evaluate the impact of hormonal excess in inducing MAFLD.
Design: a monocentric retrospective study at Padova Hospital.
Methods: a cohort of 175 patients was analyzed: 41 with PA (20 surgically treated, PAsurgery , and 21 treated with mineralcorticoid receptor antagonist, PAMRA), 50 nonfunctioning adrenal incidentalomas (NF-AI), 48 adenomas with mild autonomous cortisol secretion (MACS), 10 adrenal Cushing Syndrome (CS) and 26 healthy controls. We proposed a new definition of MAFLDendocrine, including hormonal excess as a diagnostic criteria, to assess the impact of endocrine excess in the pathogenetic process.
Results: MAFLD prevalence was higher in PA compared to MACS (49% vs 25%, p<0.05) and NF-AI (49% vs 14%, p<0.001), but similar to CS (49% vs 45%, p=0.61). PAsurgery patients had higher prevalence of both MAFLDclassical and MAFLDendocrine compared to PAMRA group (70% vs 29% MAFLDclassical and 75% vs 28% MAFLDendocrine). Within patients with hormone excess, 5/63 (8%) patients negative for MAFLDclassical fulfilled diagnostic criteria for MAFLDendocrine. L/S ratio differed between PA and NF-AI (mean L/S ratio 1.10 vs 1.25, p < 0.001), MACS (mean L/S ratio 1.10 vs 1.21, p 0.007), and controls (mean L/S ratio 1.10 vs 1.35, p < 0.001), but was comparable with adrenal CS (mean L/S 1.10 vs =1.15, p = 0.147).
Conclusions: we reported a considerable prevalence of MAFLD in PA, higher in PAsurgey compared to PAMRA, and similar to adrenal CS. MAFLDendocrine identified patients at high risk of MAFLD who do not fulfill classical diagnostic criteria
Questset
The rapid development of Virtual Reality (VR) technology has led the industry and research community to look at its major challenges with increased interest. The main challenge in ensuring a high Quality of Experience (QoE) for users is represented by cybersickness, a phenomenon similar to motion sickness experienced by many VR users, while at the same time, the high data rates needed by VR require the definition of traffic models for network optimization. These two problems are intertwined, but have never been studied jointly before due to the lack of suitable datasets. In this paper, we present Questset, the first dataset designed for this purpose. Questset contains over 40 hours of VR traces from 70 users playing commercially available video games, and includes both traffic data for network optimization, and movement and user experience data for cybersickness and QoE analysis. Therefore, Questset represents an enabler to jointly address the main VR challenges in the near future
Spatial patterns of Organic Matter content in the surface soil of the salt marshes of the Venice Lagoon (Italy)
Dataset for spatial pattern analysis of Organic Matter content in the surface soil of the salt marshes of the Venice Lagoon, Ital
Prevalence of metabolic-associated fatty liver disease in patients with primary aldosteronism
Objective: to assess the prevalence of metabolic associated fatty liver disease (MAFLD) in patients with primary aldosteronism (PA) compared to other benign adrenal nodules, and evaluate the impact of hormonal excess in inducing MAFLD.
Design: a monocentric retrospective study at Padova Hospital.
Methods: a cohort of 175 patients was analyzed: 41 with PA (20 surgically treated, PAsurgery , and 21 treated with mineralcorticoid receptor antagonist, PAMRA), 50 nonfunctioning adrenal incidentalomas (NF-AI), 48 adenomas with mild autonomous cortisol secretion (MACS), 10 adrenal Cushing Syndrome (CS) and 26 healthy controls. We proposed a new definition of MAFLDendocrine, including hormonal excess as a diagnostic criteria, to assess the impact of endocrine excess in the pathogenetic process.
Results: MAFLD prevalence was higher in PA compared to MACS (49% vs 25%, p<0.05) and NF-AI (49% vs 14%, p<0.001), but similar to CS (49% vs 45%, p=0.61). PAsurgery patients had higher prevalence of both MAFLDclassical and MAFLDendocrine compared to PAMRA group (70% vs 29% MAFLDclassical and 75% vs 28% MAFLDendocrine). Within patients with hormone excess, 5/63 (8%) patients negative for MAFLDclassical fulfilled diagnostic criteria for MAFLDendocrine. L/S ratio differed between PA and NF-AI (mean L/S ratio 1.10 vs 1.25, p < 0.001), MACS (mean L/S ratio 1.10 vs 1.21, p 0.007), and controls (mean L/S ratio 1.10 vs 1.35, p < 0.001), but was comparable with adrenal CS (mean L/S 1.10 vs =1.15, p = 0.147).
Conclusions: we reported a considerable prevalence of MAFLD in PA, higher in PAsurgey compared to PAMRA, and similar to adrenal CS. MAFLDendocrine identified patients at high risk of MAFLD who do not fulfill classical diagnostic criteria
Exo placebo order picking experimental campaign
Collection of motion capture data of an experimental campaign carried out at DTG (Department of Management and Engineering, University of Padua) for exoskeleton utilization in order picking. 53 subjects did order picking tasks with and without exoskeleton following a single blinded placebo controlled protoco
Trait emotional intelligence and endurance performance in running
Endurance running performance is influenced by several variables (e.g., physiology, anthropometric factors, biomechanics, and environmental conditions). Psychological research has shown that the management of mental fatigue can play an important role in endurance running, too (e.g., brain endurance training). Previous work has also shown that trait emotional intelligence (EI) can influence running time in a half marathon. Here, we present two studies that lend further support for the role of EI while extending the findings to a more controlled situation (the 20mSRT, a test used to assess athletes VO2max). Results showed that participants with higher (vs. lower) trait EI covered a longer distance in the test even when controlling for their height, weight, sex, and whether they do sport regularly or not. Furthermore, we showed that the effect of trait EI is mediated by participants’ subjective perception of readiness to perform. Finally, in Study 2, we replicated the findings even when participants were already tired from a previous workout and when, unbeknown to them, the test was made harder than in the baseline. These findings support the important role of psychology in endurance performance and are discussed in relation to the existing work on the variables impacting running performance
PANOMEN-3 grading score is reliable in predicting a pituitary adenoma behavior and prognosis: a single center cohort validation study
Background: Pituitary adenomas comprise a heterogeneous group of diseases, with highly variable clinical manifestations, therapies and prognosis. A validated unified scoring system to guide prognosis and therapy early on is still missing for these patients.
Methods: We prospectively assessed a retrospective large single center cohort of patients with pituitary adenomas followed at our center over the last 24 years using a newly developed Pituitary Society grading system, PANOMEN-3.
Results: In our cohort, with a long follow-up (median>8 yrs), a high initial grade predicted a worse long-term outcome despite multimodal treatments (grade 3, remission OR 0.5, 95%CI [0.24; 0.98], p=0.047). Moreover, grade could predict tumor behaviour following surgery: a higher grade at baseline predicted relapse in cured cases (p=0.014) and a higher postoperative grade predicted the need for additional treatments in case of persisting disease (p=0.04). Interestingly, a score downgrade following failed surgery also prevented further long-term interventions (p=0.01). Moreover, a score downgrade early on for patients treated with primary medical treatment predicted lack of second-tier additional interventions and medically-induced remission.
Conclusion: Our data suggest for the first time that PANOMEN-3 grade system could be useful in everyday clinical practice, aiding physicians in both improving follow-up strategies of cured patients and in the management of persisting disease for all pituitary adenomas. Further multicenter validation studies with prospective design are needed to corroborate our findings, as well as studies evaluating other important patient outcomes such as comorbidities, quality of life and survival