HAL - Normandie Université
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    The Complexity of Pure Maxmin Strategies in Two-Player Extensive-Form Games

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    International audienceExtensive-form games model strategic interaction between players, with an emphasis on the sequential aspect of decision-making: players take turns to move until an ending is reached, and receive a reward according to which ending is reached. We study the complexity of computing the pure maxmin value for such games, i.e. the maximum reward that a player can guarantee by playing a pure strategy, whatever their opponents play. We focus on two-player and two-team games and perform a systematic study depending on the degree of imperfect information of each player or team: perfect information, perfect recall, or perfect recall for each agent in a team (which we call multi-agent perfect recall). For each combination, we settle the complexity of deciding whether the maxmin value is at least as high as a given threshold. We give a complete complexity picture for three orthogonal settings: games represented explicitly by their game tree; games represented compactly by game rules, for which we propose two new formalisms; games in which the set of strategies of the opponents is restricted to a known set of opponent models

    When thinking you’re good makes you dumber: An investigation of consumers’ earned dogmatism

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    International audienceWhile dogmatism has been regarded as a personality trait in consumer research, this study delves into earned dogmatism, specifically dogmatism acquired by consumers through the accumulation of knowledge on a particular subject, leading to closed-minded cognition. Through a series of experiments, we demonstrate that subjective knowledge correlates with closed-mindedness. The data also indicate that objective knowledge moderates the relationship between subjective knowledge and closed-minded cognition, such that individuals exhibiting the highest degree of closed-mindedness are those with a significant miscalibration of their knowledge, characterized by low objective knowledge and high subjective knowledge. Finally, our findings underscore the paradox in which dogmatic individuals engage in word-of-mouth about a subject despite their closed-mindedness toward it. While previous research has demonstrated that consumer knowledge can have negative consequences for individuals, we suggest that these detrimental effects may also extend to the brands themselves, potentially leading to the dissemination of outdated or misleading information

    Évaluation de la dégénérescence graisseuse des muscles périarticulaires dans l'arthrose de hanche

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    Introduction : L’abord chirurgical optimal pour l’arthroplastie totale de hanche reste débattu. Identifier les muscles périarticulaires les moins touches par la dégénérescence graisseuse (DG) dans la coxarthrose pourrait orienter les stratégies de préservation musculaire. L’objectif de cette était de comparer la dégénérescence graisseuse des muscles périarticulaires entre des patients atteints de coxarthrose programmes pour une prothèse totale de hanche et des sujets témoins.Matériel et méthode : Nous avons analysé rétrospectivement 66 patients atteints de coxarthrose candidats a une PTH, ainsi que 56 sujets témoins (108 hanches). La dégénérescence graisseuse a été évaluée de manière indépendante par deux chirurgiens orthopédistes sur des IRM, à l’aide de la classification de Goutallier.Résultats : Les groupes étaient comparables en termes d’IMC (p = 0,92) et de sexe (p = 0,37), mais les témoins étaient significativement plus jeunes (p < 0,0001). La DG globale moyenne était plus élevée dans le groupe coxarthrose (1,31 + 0,45) que chez les témoins (1,12 + 0,44). Le groupe coxarthrose présentait une DG significativement plus élevée dans les tiers antérieur (p = 0,02) et intermédiaire (p = 0,007) du moyen glutéal, ainsi que dans le petit glutéal (p < 0,0001), l’obturateur externe (p = 0,03) et le carré fémoral (p = 0,02). Après ajustement sur l’âge, l’IMC et le sexe, seul le petit glutéal présentait une DG significativement plus élevée dans le groupe coxarthrose (p = 0,01).Conclusion : Les patients atteints de coxarthrose présentent une dégénérescence graisseuse plus marquée du petit glutéal. Néanmoins, les scores de Goutallier restent faibles dans cette population. Nos résultats ne soutiennent pas l’utilisation de la dégénérescence graisseuse comme critère déterminant dans le choix de l’abord chirurgical pour une PTH, mais renforcent l’intérêt des techniques de préservation musculaire, quelle que soit l’approche

    Enseigner la langue des signes en Bretagne :Parcours d’une enseignante en classe bilingue

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    Perquisitions : qu’importe l’occupant, pourvu qu’il soit présent: Crim. 6 mai 2025, FS-B, n° 24-85.007

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    International audienceLa Cour de cassation affirme que la perquisition réalisée au domicile d'un suspect qui n'a pas la qualité de mis en examen peut valablement avoir lieu en son absence, dès lors qu'un autre occupant est présent. En outre, elle revient dans cet arrêt sur le régime des réquisitoires introductifs et de nombreux actes d'enquête et d'instruction

    Fine-tuning the N-glycosylation of recombinant human EPO using Chlamydomonas reinhardtii mutants

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    International audienceMicroalgae are considered as attractive expression systems for the production of biologics. As photosynthetic unicellular organisms, they do not require costly and complex media for growing, and are able to secrete proteins and perform protein glycosylation (1). Some biologics have been successfully produced in the green microalgae Chlamydomonas reinhardtii. However, post-translational modifications like glycosylation of these Chlamydomonas-made biologics have poorly been investigated so far. Therefore, we reported on the first structural investigation of glycans linked to human erythropoietin (hEPO) expressed in a wild-type C. reinhardtii strain and in mutants impaired in key Golgi glycosyltransferases (2). The glycoproteomic analysis of recombinant hEPO (rhEPO) expressed in the wild-type strain demonstrated that the three N-glycosylation sites are 100% glycosylated with mature N-glycans containing four to five mannose residues and carrying core-xylose, core-fucose and O-methyl groups (Figure 1). Moreover, expression in C. reinhardtii insertional mutants defective in XYLOSYLTRANSFERASES A and B and FUCOSYLTRANSFERASE resulted in drastic decreases of core-xylosylation and core-fucosylation of glycans N-linked to the rhEPOs, thus demonstrating that this strategy offers perspectives for humanizing the N-glycosylation of the Chlamydomonas-made biologics

    Growth and characterization of strontium vanadate films deposited by reactive magnetron sputtering

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    International audienceIndium-tin oxide (ITO) is the most commonly used transparent conducting oxide (TCO) but suffers from resource depletion. Among all the alternatives to replace it, SrVO3_3 is a promising candidate which has been highly studied in recent years. In this study, structural, electrical and optical properties of 30 nm-thick films grown on low-cost substrates by reactive sputtering of a SrVO3_3 target are presented. The structural, electrical and optical properties of the obtained films have been compared with those of our previous study in which thin films were grown using a Sr2_2V2_2O7_7 target, illustrating that the use of an SrVO3_3 target allows us to obtain layers with lower roughness and better opto-electronic properties. Moreover, it was observed that the layers are non-stoichiometric compared to SrVO3_3 which can explain their semiconducting properties instead of the expected metallic behaviour

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