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    It takes a village: co-creation and co-design for social media health promotion

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    Health promotion campaigns using Social Media have emerged as a potential way to change behaviour in a large, diverse group of people. However, successfully connecting with and engaging the target audience is still a key challenge faced by health professionals and social marketers. This chapter examines the use of co-creation and co-design processes as ways to engage young people in Social Media interventions. This method involves a ‘Wicked Problems’ studio (five-day workshop), where young adults (university students) across multidisciplinary areas and a variety of stakeholders (e.g. health organisations, government bodies, academics, etc.) collaborate to problem-solve. Using this method, we were able to understand what works and what does not work when it comes to co-creation with young adults. Towards a broader outlook, the results from this study will translate into practice through the development of a how-to guide on co-creation and co-design as a procedure for key stakeholders such as government bodies and health organisations

    School reform in an era of standardization: authentic accountabilities

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    Visualising Korea: the politics of the statue of peace

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    In 2015, the Japanese imperial army's system of military sexual servitude/military prostitution once again became central to relations between South Korea and Japan. After the signing of a 2015 agreement meant to resolve disputes between the two countries, the Statue of Peace, an effigy of a young Korean woman, was reproduced in both physical form and through digital media, expanding its visual presence in both the material and virtual worlds. This study examines events between 2015 and 2018 through the lens of visual politics and argues that, to fully understand the political impact of the Statue of Peace, we need to assess it not only as a physical effigy, but also as a form of digital reproduction. In doing so, it highlights that the mechanical reproduction of the Statue of Peace freed it from the limitations of being a physical representation, and allowed it to interact in more diverse contexts as a tool of resistance against the Japanese government's proposal and the Korean government's complicity with the 2015 agreement. This study adds to the analytical toolbox of visualising Korea with the aim of providing greater insight on an important issue facing South Korea and its relationship with Japan

    Resilience achieved via multiple compensating subsystems: The immediate impacts of COVID-19 control measures on the agri-food systems of Australia and New Zealand

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    ContextSince COVID-19 (SARS-CoV-2) was first identified in the human population, it has had immediate and significant effects on peoples' health and the worldwide economy. In the absence of a vaccine, control of the virus involved limiting its spread through restrictions in the movement of people, goods and services. This has led to unprecedented impacts on labour availability, provision of goods and services, value chains, and markets.ObjectiveAgainst the backdrop of COVID-19 control measures, this article summarises quantitative and qualitative assessments of the impacts, adaptations, and opportunities to increase the resilience of the agricultural systems in Australia and New Zealand.MethodsUsing both survey and interview methodologies, we describe the various agri-food systems and the impacts of the COVID-19 control measures across different industries, and discuss the results applying a resilience framework.ResultsAs essential services, all agricultural activities except for fibre production have been permitted to continue during quarantine periods but have been exposed to the major flow-on effects of movement control. We found that, to June 2020, the impacts of the COVID-19 control measures on the agri-food sectors in both Australia and New Zealand have been relatively small and that this has been due to the high levels of resilience in the agricultural systems and the people running them.ConclusionsWe consider agri-food systems to be comprised of multiple subsystems with varying vulnerability to external influences. Agri-food systems were resilient to June 2020 at least, and that resilience was achieved via one or more subsystems that were able to compensate for the more vulnerable subsystems. We contrast the resilience of industries that have high plasticity (that can have a flow of material that can safely vary in time) to more rigid industries that are dependent on a steady flow of material with little or no storage. Ultimately both types of industries were resilient, but they achieved that resilience via compensating subsystems. High plasticity industries relied on their production and processing subsystem; rigid industries engaged their institutional subsystem to achieve the same end. The social and cultural subsystem was important across all industries.SignificanceIt is not yet clear if the current resilience mechanisms can persist under the continued onslaught of the virus. We indicate the need to capture longer term effects and analysis during the more sustained effects of the virus and through a recovery period. We anticipate a follow-up study in 2022

    Discrete element and finite element methods provide similar estimations for hip joint contact mechanics during walking gait

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    Finite element analysis (FEA) provides a powerful approach for estimating the\ua0in-vivo\ua0loading characteristics of the hip joint during various locomotory and functional activities. However, time-consuming procedures, such as the generation of high-quality FE meshes and setup of FE simulation, typically make the method impractical for rapid applications which could be used in clinical routine. Alternatively, discrete element analysis (DEA) has been developed to quantify mechanical conditions of the hip joint in a fraction of time compared to FEA. Although DEA has proven effective in the estimation of contact stresses and areas in various complex applications, it has not yet been well characterised by its ability to evaluate contact mechanics for the hip joint during gait cycle loading using data from several individuals. The objective of this work was to compare DEA modelling against well-established FEA for analysing contact mechanics of the hip joint during walking gait. Subject-specific models were generated from magnetic resonance images of the hip joints in five asymptomatic subjects. The DEA and FEA models were then simulated for 13 loading time-points extracted from a full gait cycle. Computationally, DEA was substantially more efficient compared to FEA (simulation times of seconds vs. hours). The DEA and FEA methods had similar predictions for contact pressure distribution for the hip joint during normal walking. In all 13 simulated loading time-points across five subjects, the maximum difference in average contact pressures between DEA and FEA was within ±0.06\ua0MPa. Furthermore, the difference in contact area ratio computed using DEA and FEA was less than ±6%

    Identification of monoclonal antibodies suitable for blocking IGF-1 receptors in the horse

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    Prolonged hyperinsulinemia is thought to be the cause of equine endocrinopathic laminitis, a common and crippling disease of the foot, for which there are no pharmacologic treatments other than pain relief. It has been suggested that insulin causes its effects on the lamellae by activating IGF-1 receptors (IGF-1R), as insulin receptors (InsR) are scarce in this tissue, whereas IGF-1R are abundant and become downregulated after prolonged insulin infusion. As a first step toward confirming this mechanism and beginning to develop a therapeutic anti–IGF-1R monoclonal antibody (mAb) for horses, it was necessary to identify available human IGF-1R mAbs that would recognize equine receptors. Four IGF-1R mAbs were tested using soluble equine IGF-1R, with ELISA and flow cytometry. Frozen equine lamellar and liver tissue was also used in radioligand binding assays. The results demonstrated that only one of the mAbs tested (mAb1) was able to compete effectively with IGF-1 for binding to its receptors in equine lamellar tissue, with an IC of 5 to 159 ng/mL. None of the 4 mAbs were able to bind to equine hepatic InsR. This study has generated valuable structure-activity information and has identified a prototype anti–IGF-1R mAb suitable for further development

    In-situ surface self-reconstruction in ternary transition metal dichalcogenide nanorod arrays enables efficient electrocatalytic oxygen evolution

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    Water splitting has received more and more attention because of its huge potential to generate clean and renewable energy. The highly active and durable oxygen evolution reaction (OER) catalysts play a decisive factor in achieving efficient water splitting. The identification of authentic active origin under the service conditions can prompt a more reasonable design of catalysts together with well-confined micro-/nano-structures to boost the efficiency of water splitting. Herein, Fe, Co, and Ni ternary transition metal dichalcogenide (FCND) nanorod arrays on Ni foam are purposely designed as an active and stable low-cost OER pre-catalyst for the electrolysis of water in alkaline media. The optimized FCND catalyst demonstrated a lower overpotential than the binary and unary counterparts, and a 27-fold rise in kinetic current density at the overpotential of 300 mV compared to the nickel dichalcogenide counterpart. Raman spectra and other structural characterizations at different potentials reveal that the in-situ surface self-reconstruction from FCND to ternary transition metal oxyhydroxides (FCNOH) on catalyst surfaces initiated at about 1.5 V, which is identified as the origin of OER activity. The surface self-reconstruction towards FCNOH also enables excellent stability, without fading upon the test for 50 h

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