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    Single Layer Dual Circularly Polarized Series-fed Gap Waveguide Based Slot Array for 77 GHz Automotive Radar

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    A series-fed single layer dual circularly polarized slot array antenna fed by stepped ridge gap waveguide is proposed at the 77 GHz band. The antenna generates dual circularly polarized waves, which shows potential to be used in next-generation polarimetric radar for automotive applications. The antenna contains 8 columns of linear arrays and two feeding ports for exciting the columns of the slots. The design process and measured results are described in this paper. The measured results show that the realized gain of the proposed antenna is above 27.3 dBi and the axial ratio is about 2 dB over the proposed 76-79 GHz with dual CP patterns. The measured S11 and S22 for the proposed antenna is below -10 dB and the measured port isolation is above 17.5 dB

    Near-infrared Polarimetry and H2 Emission toward Massive Young Stars: Discovery of a Bipolar Outflow Associated to S235 e2s3

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    We present a near-infrared H-band polarimetric study toward the S235 e2s3 protostar, obtained using the POLICAN instrument on the 2.1 m OAGH telescope. The images reveal a bipolar outflow with a total length of about 0.5 pc. The outflow nebulosity presents a high degree of linear polarization (∼80%) and reveals a centrosymmetric pattern with the polarization position angles. The polarization characteristics suggest their origin to be single scattering associated with dust in the outflow. Using multiwavelength archival data, we performed spectral energy distribution (SED) fitting based on radiative transfer models of turbulent core accretion theory. The best-fit SED model indicated that the protostar has a mass of 6.8 \ub1 1.2 M ⊙, with a disk accretion rate of 3.6 \ub1 1.2 7 10−4 M ⊙ yr−1 and a total bolometric luminosity of 9.63 \ub1 2.1 7 103 L ⊙. Narrowband H2 (2.12 μm) observations show shocked emission along the bipolar lobes tracing the jet’s interaction with the surrounding medium. The estimated H2 luminosity of the outflow is 2.3 − 1.3 + 3.5 L ⊙ , which matched the known power-law correlation with the source bolometric luminosity, similar to other high-mass outflows. The orientation of the bipolar outflow was found to be parallel to the local magnetic field direction. The overall results assert the fact that the S235 e2s3 source is a massive young star driving a highly collimated bipolar outflow through disk accretion

    A Corrugated Planar-Goubau-Line Termination for Terahertz Waves

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    The planar Goubau line is a promising low-loss metal waveguide for terahertz applications. To enable advanced circuits and multi-port measurements based on planar Goubau lines, there is a strong need for broadband impedance-matched loads, which can be used to absorb the energy and minimize standing waves in a system. In this work, we propose a termination for planar Goubau lines based on an exponentially-tapered corrugated line, gradually increasing conductor losses while maintaining small reflections. The corrugation density is high enough to increase conductor losses without requiring an auxiliary low-conductivity material. A 400-\ub5m long planar Goubau line load was fabricated on a 10-\ub5m thick silicon substrate suspended in the air. Simulations of the load show excellent agreement with calibrated reflection measurements in the frequency range 0.5 THz – 1.1 THz. Above the cut-off frequency of around 580 GHz, the measured reflections are less than -19 dB, below the noise floor of the characterization setup

    The Dark side of Obesity: Multi-omics analysis of the dysmetabolic morbidities spectrum

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    Obesity is one of the most prevalent clinical conditions worldwide and is associated with a wide spectrum of dysmetabolic comorbidities. Complex cardio-metabolic disease cohorts, such as obesity cohorts are characterised by population heterogeneity, multiple underlying diseases status and different comorbidities’ treatment regiments. The systematic collection of multiple types of clinical and biological data from such cohorts and the data-analysis in an integrative manner is a challenging task due to the variables’ dimensionality and the lack of standardised know-how of post-processing.The main resource of this thesis has been the BARIA cohort, a detailed collection over time of multiple omics and demographic data from participants in bariatric surgery. BARIA datasets included plasma metabolites, RNA from hepatic, jejunal, mesenteric and subcutaneous adipose tissues and gut microbial metagenome, besides biometric data. The work presented in this thesis included the development of a systems biology integrative framework based on BARIA that (i) utilised unsupervised machine learning algorithms, self-organizing maps in particular, and multi-omics integrative frameworks, the DIABLO library, in order to stratify the BARIA heterogeneous obesity cohort and predict the bariatric surgery’s outcome. The thesis covered how BARIA can be the onset for (ii) studying molecular mechanisms related to type 2 diabetes (T2D) and G-protein coupled receptors (GPCRs) and for identifying a minimal set of biomarkers for obesity’s comorbidities such as (iii) non-alcoholic fatty liver disease (NAFL) and (iv) gallstones formation after bariatric surgery.The results indicated that the metabotypes comprising a bariatric surgery cohort exhibited a concrete metabolic status and different responses over time after the bariatric surgery. It has been demonstrated how obesity and T2D associated metabolites, such as 3-hydroxydecanoate, can increase inflammatory responses via GPCRs molecular activation and signalling. Last but not least, minimal sets of both evasive and non-evasive multi-omic discriminatory biomarkers for obesity’s dysmetabolic morbidities (NAFLD and gallstones after bariatric surgery) were obtained. Taking into consideration all the findings, this thesis presented how data-driven approaches can be used for studying in-depth heterogeneous cohorts, hereby facilitating early diagnosis and enabling potential preventive actions

    Effects of adsorbed molecular ordering to the superconductivity of a two-dimensional atomic layer crystal

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    The effect of 3,4,9,10-perylenetetracarboxylic dianhydride (PTCDA) adsorption on the physical properties of the two-dimensional (2D) atomic layer superconductor (ALSC) In/Si(111)-(7 73) has been studied by angle-resolved photoelectron spectroscopy, transport measurements, and scanning tunneling microscopy. Hole doping from the adsorbed molecules has been reported to increase the superconducting transition temperature Tc of this ALSC, and the molecular spin tends to decrease it. Owing to its large electron affinity and its nonexistent spin state, the adsorption of PTCDA was expected to increase Tc. However, the PTCDA adsorption dopes only a small number of holes in the In layers and causes a suppression of Tc with a sharp increase in the normal-state sheet resistance followed by an insulating transition. Taking the disordering of the arrangement of PTCDA into account, we conclude that the increase in resistance is due to the localization effect originating from the random potential that is induced by the disordered PTCDA molecules. The present result also indicates the importance of the crystallinity of a 2D molecular film adsorbed on ALSCs

    Improved computations for relationship inference using low-coverage sequencing data

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    Pedigree inference, for example determining whether two persons are second cousins or unrelated, can be done by comparing their genotypes at a selection of genetic markers. When the data for one or more of the persons is from low-coverage next generation sequencing (lcNGS), currently available computational methods either ignore genetic linkage or do not take advantage of the probabilistic nature of lcNGS data, relying instead on first estimating the genotype. We provide a method and software (see familias.name/lcNGS) bridging the above gap. Simulations indicate how our results are considerably more accurate compared to some previously available alternatives. Our method, utilizing a version of the Lander-Green algorithm, uses a group of symmetries to speed up calculations. This group may be of further interest in other calculations involving linked loci

    PKS 1413+135: OH and H i at z = 0.247 with MeerKAT

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    The BL Lac object PKS 1413+135 was observed by the Large Survey Project MeerKAT Absorption Line Survey (MALS) in the L-band, at 1139 MHz and 12931379 MHz, targeting the HI and OH lines in absorption at z=0.24671. The radio continuum might come from the nucleus of the absorbing galaxy or from a background object at redshift lower than 0.5, as suggested by the absence of gravitational images. The HI absorption line is detected at a high signal-To-noise ratio, with a narrow central component, and with a red wing, confirming previous results. The OH 1720 MHz line is clearly detected in (maser) emission, peaking at a velocity shifted by-10 to-15 km s-1 with respect to the HI peak. The 1612 MHz line is lost due to radio frequency interference. The OH 1667 MHz main line is tentatively detected in absorption, but not the 1665 MHz line. Over 30 years a high variability is observed in optical depths, due to the rapid changes of the line of sight caused by the superluminal motions of the radio knots. The HI line has varied by 20% in depth, while the OH-1720 MHz depth has varied by a factor of ∼3. The position of the central velocity and the widths also varied. The absorbing galaxy is an early-Type spiral (maybe S0) seen edge-on, with a prominent dust lane, covering the whole disk. Given the measured mass concentration and the radio continuum size at centimeter wavelengths (100 mas corresponding to 400 pc at z=0.25), the width of the absorption lines from the nuclear regions are expected up to 250 km s-1. The narrowness of the observed lines (< 15 km s-1) suggests that the absorption comes from an outer gas ring, as frequently observed in S0 galaxies. The millimetric lines are even narrower (< 1 km s-1), which corresponds to the continuum size restricted to the core. The radio core is covered by individual 1 pc molecular clouds, whose column density is a few 1022 cm-2, which is compatible with the gas screen detected in X-rays

    Experimental evidence of the effect of nuclear shells on fission dissipation and time

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    Nuclear fission is still one of the most complex physical processes we can observe in nature due to the interplay of macroscopic and microscopic nuclear properties that decide the result. An example of this coupling is the presence of nuclear dissipation as an important ingredient that contributes to drive the dynamics and has a clear impact on the time of the process. However, different theoretical interpretations, and scarce experimental data make it poorly understood. In this Letter, we present the first experimental determination of the dissipation energy in fission as a function of the fragment split, for three different fissioning systems. The amount of dissipation was obtained through the measurement of the relative production of fragments with even and odd atomic numbers with respect to different initial fission energies. The results reveal a clear effect of particular nuclear shells on the dissipation and fission dynamics. In addition, the relative production of fragments with even and odd atomic numbers appears as a potential contributor to the long-standing problem of the time scale in fission

    Validation of PANS and effects of ground and wheel motion on the aerodynamic behaviours of a square-back van

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    This paper presents a numerical investigation of the effects of the moving ground and rotating wheels on the turbulent flow around a 1/10 scaled square-back van model. A comprehensive comparison among the partially averaged Navier-Stokes (PANS), large eddy simulation (LES) and particle image velocimetry (PIV) involving the aerodynamic drag, the wake topology, the velocity and the Reynolds stress profiles in the wake region is conducted. The proper orthogonal decomposition (POD) and fast Fourier transform (FFT) are applied to the shear layers shedding from the trailing edges to comment on the coherent structures and their frequency content. The Reynolds number for both simulations and experiments is set to Re = 2.5 7 105 based on the inlet velocity and the width of the model W = 0.17 m. The results show that PANS accurately predicts the flow field measured in experiments and predicted by a resolved LES, even with a low-resolution grid. The superiority of the PANS approach could provide good guidance for industrial research in predicting the turbulent flow around the square-back van model with affordable computational grids. The ground and wheel motion mechanism on the aerodynamic forces has been revealed by analysing the surface pressure distribution, the wheels\u27 surrounding flow, the underbody flow characteristics and the turbulent wake structures. The effects of the ground and wheel motion on the frequency, evolution and development characteristics of the wake shear layers are analysed, thus providing relevant insights for future experimental investigations of square-back van models

    Fluorescence excitation enhancement by waveguiding nanowires

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    The optical properties of vertical semiconductor nanowires can allow an enhancement of fluorescence from surface-bound fluorophores, a feature proven useful in biosensing. One of the contributing factors to the fluorescence enhancement is thought to be the local increase of the incident excitation light intensity in the vicinity of the nanowire surface, where fluorophores are located. However, this effect has not been experimentally studied in detail to date. Here, we quantify the excitation enhancement of fluorophores bound to a semiconductor nanowire surface by combining modelling with measurements of fluorescence photobleaching rate, indicative of the excitation light intensity, using epitaxially grown GaP nanowires. We study the excitation enhancement for nanowires with a diameter of 50-250 nm and show that excitation enhancement reaches a maximum for certain diameters, depending on the excitation wavelength. Furthermore, we find that the excitation enhancement decreases rapidly within tens of nanometers from the nanowire sidewall. The results can be used to design nanowire-based optical systems with exceptional sensitivities for bioanalytical applications

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