Archivio istituzionale della Ricerca - Università degli Studi di Parma
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Correction to: Characterisation of Fault-Related Mn-Fe Striae on the Timpa Della Manca Fault (Mercure Basin, Southern Apennines, Italy) (Geosciences, (2024), 14, 11, (299), 10.3390/geosciences14110299)
No full textWhere Are All the Clinical Trials for Chronic Rejection?
No full text: Chronic rejection is arguably the main obstacle to long-term graft survival. Yet, clinical trials focusing on this condition are disappointingly scarce. Significant advances in treating chronic rejection cannot happen if there is no conduit for testing novel therapies. Here, we identified the main hurdles holding back clinical trials for chronic rejection and outlined a series of actions to address these roadblocks. We suggest that a new strategic plan combining expertise in basic and clinical research and leveraging complementary resources be launched to specifically target chronic rejection and achieve long-awaited progress. We only need the will
Il romanzo cattolico dopo Manzoni. Strategie editoriali e narrative del secondo Ottocento
No full textDifferential Expression of miR-223-3p and miR-26-5p According 2 to Different Stages of Mastitis in Dairy Cows
No full textMastitis is the leading cause of economic losses in dairy farming, significantly impairing 14
animal welfare and the quality and quantity of milk production. MicroRNAs are increasingly gain- 15
ing attention, in both human and veterinary medicine, as biomarkers for various diseases. This 16
study evaluated the diagnostic potential of four circulating microRNAs (miR-26-5p, miR-142-5p, 17
miR-146a, and miR-223-3p) by examining changes in their expression in milk samples from dairy 18
cows at different immune cells subpopulations correlated to different stage of mastitis in validated 19
method. Additionally, the study has analysed the possible source of these circulating microRNA by 20
the measurement of their secretion from activated immune cells (lymphocytes, monocytes, and neu- 21
trophils). miR-223-3p has been significantly expressed in acute stage of mastitis (p<0.01) but not in 22
the chronic or susceptible stages. Conversely, mir-26-5p has been significantly reduced in acute, 23
chronic and susceptible groups of animals. In immune cell cultures miR-26 has been shown to 24
downregulated in Lypopolysaccharide (LPS)-stimulated neutrophils while miR-223 has been 25
shown to be upregulated in Phytohaemagglutinin (PHA)-stimulated lymphocytes. The differential 26
expression of miR-223-3p and miR-26-5p, combined with differential and total somatic cell count, 27
could serve as a useful tool for identifying the evolutionary stage of mastitis-related inflammatory 28
patholog
A Novel Modular Data Acquisition System for Distributed Monitoring of Partial Discharge in Industrial Drives
No full textInsulation fault detection in rotating machinery using Partial Discharge (PD) has been a hot research topic over the last decades. In recent years, attention has also been paid to low voltage machines, following the advent of wide bandgap semiconductor devices. However, most of the solutions currently available are based on analog technology, which entails high costs, bulky wiring, and long installation times, making them unattractive for the market. This paper presents a low-cost, modular, and full-digital PD monitoring device, which implements a Capacitive Coupling (CC) front end for PD conditioning and an innovative, digital monitoring network, based on the Automotive Audio Bus (A2B), particularly suitable for deployment in large industrial plants, ensuring complete coverage and continuous monitoring of critical machinery without suffering of electromagnetic disturbances. The proposed system has been simulated in PSpice, then built and tested against a reference, consisting of a laboratory grade oscilloscope, using two different PD interfaces: CC and High Frequency Current transformer (HF-C). The comparison was carried out by subjecting a low voltage induction motor to a standard PD test to evaluate PD inception voltage detection with the different methods. The digital oscilloscope demonstrated a slightly better sensitivity concerning the onset PD voltage threshold, 1.3 - 1.35 kV. The proposed monitoring device on the other hand exhibits a greater robustness at transition voltages, being less prone to false positives. The two systems are equivalent at 1.4 kV while the proposed solution performs significantly better at higher voltages, with 6 PD events per cycle detected at 1.5 kV in place of 3. The HF-C transducer demonstrated even greater sensitivity at these voltage levels, with 7.6 PD detections per cycle at 1.5 kV. The results show that the proposed PD CC sensor has satisfactory sensitivity towards detecting onset of PD activity and appears less susceptible to noise than the digital oscilloscope CC sensor
A discrete fiber dispersion model with octahedral symmetry quadrature for mechanical analyses of skin corrective surgeries
No full textAdvanced simulations of the mechanical behavior of soft tissues frequently rely on structure- based constitutive models, including smeared descriptions of collagen fibers. Among them, the so-called Discrete Fiber Dispersion (DFD) modeling approach is based on a discrete integration of the fiber-strain energy over all the fiber directions. In this paper, we review the theoretical framework of the DFD model, including a derivation of the stress and stiffness tensors required for the finite element implementation. Specifically, their expressions for incompressible plane stress problems are obtained. The use of a Lebedev quadrature, built exploiting the octahedral symmetry, is then proposed, illustrating the particular choice adopted for the orientation of the integration points. Next, the convergence of this quadrature scheme is assessed by means of three numerical benchmark tests, highlighting the advantages with respect to other angular integration methods available in the literature. Finally, using the implemented model, we analyze the mechanical properties of the Z-plasty, a technique commonly used in reconstructive skin surgery, considering multiple geometrical configurations, orientations of the fibers, and levels of skin prestress. The results are presented in the form of mechanical quantities relevant to surgical practice
Anisotropic superconductivity in the quasi-one-dimensional superconductor V2Ga5
No full text: The intermetallic quasi-one-dimensional binary superconductor V2Ga5 was recently found to exhibit a topologically nontrivial normal state, making it a natural candidate for a topological superconductor. By combining dc-magnetization, nuclear magnetic resonance, and muon-spin rotation ([Formula: see text]SR) measurements on high-quality V2Ga5 single crystals, we investigate the electronic properties of its normal- and superconducting ground states. NMR measurements in the normal state indicate a strong anisotropy in both the line shifts and the relaxation rates. Such anisotropy persists also in the superconducting state, as shown by the magnetization- and [Formula: see text]SR-spectroscopy results. In the latter case, data collected at different temperatures, pressures, and directions of the magnetic field evidence a fully-gapped, strongly anisotropic superconductivity. At the same time, hydrostatic pressure is shown to only lower the [Formula: see text] value, but not to change the superfluid density nor its temperature dependence. Lastly, we discuss the search for topological signatures in the normal state of V2Ga5, as well as a peak splitting in the FFT of the [Formula: see text]SR spectrum, possibly related to an unconventional vortex lattice. Our results suggest that V2Ga5 is a novel system, whose anisotropy plays a key role in determining its unusual electronic properties
Corrigendum to “Clinical efficacy of inhaled corticosteroids in equine asthma: A meta-analysis and number needed to treat” [Pulm. Pharmacol. Therapeut. (88), March 2025, 102342] (Pulmonary Pharmacology & Therapeutics (2025) 88, (S1094553924000580), (10.1016/j.pupt.2024.102342))
No full textThe authors regret that the previously published Fig. 1 contained an error in the section “Identification of studies via other methods.” The incorrect Figure indicated n = 1 report not retrieved, whereas the correct amended Figure indicates that n = 0 reports were not retrieved. The correct Fig. 1 is shown below. The authors would like to apologise for any inconvenience caused.[Figure presented
Improving the Raman Model for Dravite and Schorl Tourmalines by μXANES Analysis of Iron Oxidation States
No full textTourmalines, a complex borosilicate mineral supergroup, are significant in geological studies due to their chemical and mechanical stability across various temperature and pressure conditions, making them useful as source rock indicators. A major issue in the characterization of tourmaline composition is the consideration of the iron oxidation state, which can significantly influence the distribution of elements at each site. This study reports the enhancement of a previous model that correlates Raman spectral parameters of dravite-schorl tourmalines with their composition, taking into account the Fe valence state in Y and Z sites measured through micro-x-ray absorption near edge structure (mu XANES) spectroscopy. Raman spectroscopy was employed in a prior study on these two tourmaline species by correlating peak positions and intensities with differences in the magnesium-iron ratio. However, it was assumed that all iron was in the ferrous oxidation state (Fe2+), which led to a misrepresentation of the Fe3+ content in certain samples. The model has been thus implemented in this work by using mu XANES, enabling the accurate quantification of Fe2+ and Fe3+ in dravite-schorl minerals, hence refining Mg/(Mg + Fe2+) ratios for Raman spectral analysis. Results demonstrate the validity of the correlation between Raman peaks in both the fingerprint and OH stretching regions and the magnesium-ferrous iron ratio. Our research confirms that Raman spectrum analysis is an effective method for recognizing tourmalines from the dravite-schorl series and evaluating their composition, including now the evaluation of the Fe2+ and Fe3+ occupancy. By integrating mu Raman and mu XANES techniques, one can acquire insights into the oxidation state of iron in tourmalines from the dravite-schorl series, thereby enhancing the accuracy of the Mg/(Mg + Fe2+) ratio. The observed linear correlations for P2 peak position, P1/P2 relative intensities, and WOH(3) peak position in the Raman spectrum enable the rapid identification of dravite and schorl tourmalines, as well as the retrieval of relative Mg and Fe2+ contents