Archivio Istituzionale della Ricerca- Università del Salento
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A Case of marinistic Poetry in Latin: Girolamo Cicala's "Carmina".
No full textGirolamo Cicala’s collection was printed posthumously in Lecce in 1649. While it
might initially seem to be the product of an out-of-season humanism, it actually serves
as a significant case study. Seventeenth-century Latin poetry is often considered, at
least in Italy, to be a counterbalance to the experimentalism found in the works of
Giovan Battista Marino and his followers, or as a field of literature largely dominated
by the Jesuits for didactic purposes. However, Girolamo Cicala’s Latin poems demonstrate
that there was indeed a strand of Marinist poetry in Latin, characterized by the
same novelty and experimentalism that defined poetry in Italian. Cicala reinterprets
the metres and themes of the classical tradition, aligning them with the new poetic
orientation, in harmony with southern Baroque lyricism, and as a testament to his
belonging to the same geo-literary context
Diritto, digital humanities e conservazione del patrimonio culturale. Crome e cabinet: due esperienze transdisciplinari
No full textil presente contributo, che intende riflettere su una serie di esperienze di ricerca e innovazione didattica nate all’intersezione tra diritto, sociologia e conservazione del patrimonio culturale, con l’obiettivo di mostrare come queste discipline possano dialogare proprio a partire da un approccio conversazionale alla conoscenza. Al centro della riflessione si pongono due progetti – CroMe (Culture as a Good
and as a Medium) e Cabinet – che, pur partendo da ambiti diversi, convergono in una comune attenzione alla valorizzazione della ricerca scientifica come patrimonio culturale immateriale, nonché alla sperimentazione di forme innovative di comunicazione, partecipazione e apprendimento
The Role of Vitamin D in Inflammatory Bowel Diseases: From Deficiency to Targeted Therapeutics and Precise Nutrition Strategies
No full textBackground: Vitamin D plays a crucial role in immune modulation, gut barrier integrity, and inflammation regulation, making it highly relevant in inflammatory bowel disease (IBD). IBD patients often exhibit vitamin D deficiency, which has been linked to increased disease activity, impaired mucosal healing, and a higher risk of complications, including infections and osteoporosis. Methods: This review examines the biological functions of vitamin D in maintaining intestinal homeostasis, particularly in the context of IBD. It discusses the prevalence and consequences of vitamin D deficiency in IBD, including its potential to exacerbate disease progression, impair treatment efficacy, and negatively impact long-term health outcomes. Furthermore, therapeutic strategies to address vitamin D deficiency are explored, including supplementation approaches, dosing strategies, and precision nutrition interventions that aim to personalize vitamin D management based on individual patient needs and disease characteristics. Results: By synthesizing the latest evidence, this review highlights the critical role of vitamin D in IBD management, underlining how optimal vitamin D levels may not only improve disease control but also enhance patient quality of life and reduce the risk of long-term complications associated with the disease. Conclusions: Understanding the importance of vitamin D in IBD could help refine treatment strategies and promote better health outcomes for affected individuals
The Spatial Distribution of Biodiversity
No full textThe chapter introduces the spatial distribution of biodiversity in landscapes. This distribution is strongly interconnected and depends on the spatial structure and characteristics of the territory elements of the landscape that have always hosted living species and communities and with which they have coevolved over time in close interrelation, highlighting the importance of landscape structure and habitat layout patches in determining species distribution patterns. A new approach to analyze the cross-scale spatial distribution of biodiversity is introduced in this perspective
Impact of polyethylene terephthalate nanoplastics (PET) on fibroblasts: a study on NIH-3T3 cells
No full textPlastic pollution has become a major environmental and public health issue due to rising global production. Nanoplastics (NPs) are especially concerning due to their widespread presence and potential health risks. This study aims to determine the impact of the exposure to polyethylene terephthalate (PET) NPs on fibroblast cells using the murine NIH-3T3 cells as experimental model. This is a relevant cellular model for several biological fields of application, including cell migration in wound healing and tissue regeneration. The PET NPs used represented an environmentally realistic PET NPs model since they were produced by a fast top down approach in a process close to the mechanical abrasion of microplastics occurring in the environment. They were characterized by an intrinsic autofluorescence which enables their use in studies of NPs interactions with biological systems without the need for additional fluorescent dyes. Additionally, the Hansen solubility parameters (HSP) of the PET NPs and the culture medium were determined to better understand their interaction. PET NPs were internalized by fibroblasts in a dose-dependent manner, localizing in the cytoplasm. While they caused only a slight reduction in cell viability (within 20% inhibition at 10–100 μg/mL) after 24 h exposure, they significantly impaired fibroblast migration, as demonstrated by the scratch assay, indicating possible interference in tissue repair. The exposure of the cells to PET NPs induced a significant dose-dependent ROS increase suggesting the induction of intracellular oxidative stress as possible mechanisms underlying the observed migration impairment. These findings highlight the potential risks of PET NPs to fibroblasts, emphasizing the need for further research into their impact on cellular functions and mechanisms
The dual impact of digital lending on European banks. How do Fintech platforms affect bank stability and loan portfolio quality?
No full textThis chapter, focusing on digital lending, examines this impact on bank stability and loan portfolio quality. Digital lending poses a challenge to the stability of traditional banks but does improve the quality of loan portfolios by reducing non-performing loans. The chapter emphasizes the necessity for collaborative models and balanced regulations that can enable the provision of the benefits and risks of digital lending to harmonize
Insight into the Regulation of NDRG1 Expression
Full text linkThe N-Myc Downstream Regulated Gene 1 (NDRG1) protein, a member of a family of four, has emerged as a key regulator of various physiological and pathological processes. Extensive knowledge has been gained on the modulation of NDRG1 expression during endoplasmic reticulum stress, autophagy, and hypoxia. Moreover, new functions have emerged in recent years. Notably, NDRG1 regulates cell differentiation, metabolism, autophagy and vesicular transport. This has raised interest in the molecular mechanisms that control the cellular levels and activity of NDRG1. A series of studies have shown that NDRG1 can be finely regulated at the transcriptional, post-transcriptional, and translational levels. In addition, processes that mediate protein degradation and clearance also play key roles. Furthermore, three different NDRG1 proteoforms with distinct functions have been identified. An important question is the extent to which these proteoforms contribute to the regulation of cellular functions. Given the growing clinical interest in NDRG1, this review provides an overview of the regulatory mechanisms that control NDRG1 abundance, helping to deepen our understanding of the complex mechanisms underlying protein regulation
Artificial intelligence and IoT for water saving in agriculture: A systematic review
Full text linkSmart irrigation and fertigation offer three key benefits: sustainability through water conservation, increased productivity via targeted fertigation that activates only when necessary, and enhanced efficiency through remote control and high-precision sensors. This document presents a comprehensive review of the most significant innovations in this field over the past five years. The main components analyzed include sensors for monitoring and data acquisition, protocols and Internet of Things architectures for network management, and Artificial Intelligence models for decision-making and predictions. This study followed the PRISMA 2020 protocol and made use of data from Scopus and Web of Science. A total of 130 articles were identified as relevant and examined in detail. Alongside summarizing the collected articles, the review also includes an analysis of proposed future developments to inspire new research and drive innovation in this domain