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Beta-oksidacija u modelu kvasca Barthovog sindroma
Barth syndrome is a complicated and life-threatening systemic disease. It is characterized by a wide range of conditions, mostly affecting the heart and skeletal muscles. Symptoms include cardiomyopathy, skeletal myopathy, neutropenia, increased urinary excretion of 3-methylglutaconic acid and weaker motor skills. Being a genetic disease, it is currently uncurable and is managed through medications that decrease symptom severity. The syndrome is caused by mutations in the TAZ gene which encodes the tafazzin enzyme. Tafazzin has an important role in the cardiolipin synthesis and remodeling pathway. Cardiolipin is a unique phospholipid that makes up a significant portion of the inner mitochondrial membrane. It goes through a complex and highly conserved synthesis and remodeling pathway which is altered in patients with Barth syndrome. Unlike other phospholipids, cardiolipin has a specific structure that differs from other phospholipids and enables it to interact with various membrane proteins and complexes, playing a crucial role in maintaining mitochondrial energy metabolism. By gaining a deeper understanding of the molecular mechanisms and the significance of cardiolipin synthesis and remodeling, new treatment strategies could be developed. These strategies would target the underlying cause of the disease, unlike currently available therapeutic approaches. One potential target is beta-oxidation. Trimetazidine, a drug commonly used to treat heart conditions, inhibits beta-oxidation and has been shown in previous studies to affect mitochondrial phospholipid turnover. However, its impact on cardiolipin synthesis and turnover remains unknown. In this research, we are interested in investigating if inhibition of beta-oxidation enhances mitochondrial phospholipid turnover and increases the levels of functional cardiolipin in cells with TAZ deficiencies. Saccharomyces cerevisiae serves as an excellent model organism for studying Barth syndrome because all the enzymatic steps involved in cardiolipin synthesis and remodeling are conserved between yeast and humans.Barthov sindrom je složena, po život opasna bolest koja zahvaća cijeli organizam. Karakteriziran je širokim spektrom simptoma, koji uglavnom zahvaćaju srce i tjelesne mišiće. Simptomi uključuju kardiomiopatiju, skeletnu miopatiju, neutropeniju, povećano izlučivanje 3-metilglutakonske kiseline putem urina te slabije motoričke sposobnosti. Kao genetska bolest je neizlječiva, a pacijenti se tretiraju lijekovima koji ublažavaju prisutne simptome. Bolest je uzrokovana mutacijama u TAZ genu koji kodira enzim tafazzin. Tafazzin ima važnu ulogu u sintezi i remodeliranju kardolipina. Kardolipin je specifičan fosfolipid koji čini značajan udio unutarnje membrane mitohondrija. Prilikom sinteze i remodeliranja, kardiolipin prolazi složen i evolucijski očuvan put koji je izmijenjen kod pacijenata s Barthovim sindromom. Za razliku od većine fosfolipida, kardolipin ima specifičnu strukturu koja mu omogućuje interakciju s raznim proteinskim kompleksima u mitohondriju. Ovo svojstvo omogućava ključnu ulogu kardiolipina u održavanju mitohondrijskog energetskog metabolizma. Boljim razumjevnjem značaja i molekularnog mehanizma sinteze kardiolipina, mogle bi se razviti nove strategije u liječenju Barthovog sindroma. Jedna potencijalna strategija je inhibicija beta-oksidacije. Trimetazidin, lijek koji se koristi za liječenje srčanih oboljenja, inhibira beta-oksidaciju te prema prethodnim istraživanjima, utječe na promjenu sastava mitohondrijskih fosfolipida. Međutim, utjecaj trimetazidina na kardiolipin je nepoznat. U ovom istraživanju nastojimo ispitati može li inhibicija beta-oksidacije povećati promjenu mitohondrijskih fosfolipida i povećati razine funkcionalnog kardolipina u stanicama s TAZ mutacijama. Saccharomyces cerevisiae je izvrstan modelni organizam za proučavanje Barthovog sindroma jer su svi enzimski koraci uključeni u sintezu i remodeliranje kardolipina evolucijski očuvani između kvasca i ljudi
Društveni ugled pravne profesije u Hrvatskoj - pogled iznutra
Republika Hrvatska 2023. godine obilježila je deset godina članstva u Europskoj uniji. Ipak, put Hrvatske u samostalnost i Europsku uniju te transformacija hrvatskog društva i njegovih (pod)sustava, koji su se u tim kontekstima odvijali obilježeni su brojnim izazovima i problemima. lako su, općenito gledano, iskustva većine postsocijalističkih zemalja koje su krenule u tranziciju u zadnjem desetljeću dvadesetog stoljeća, pokazala da je demokratska tranzicija razmjerno dugotrajan i tegoban proces. Hrvatska je u tom procesu imala i svoje specifičnosti
CAUSAL VARIANTS OF THALASSEMIA SYNDROMES IN THE POPULATION OF THE CROATIAN LITTORAL AND ISTRIA
Cilj istraživanja: Istražiti uzročne varijante talasemijskih sindroma u populaciji Hrvatskog
primorja i Istre te ih usporediti s uzročnim varijantama u drugim populacijama. Specifični
ciljevi su ispitati hematološke, biokemijske i kliničke značajke u pojedinaca s talasemijskim
sindromima, utvrditi korelaciju genotipa i fenotipa te izraditi algoritam za molekularno
genetičku dijagnostiku talasemija.
Materijal i metode: U presječno istraživanje je uključeno 112 ispitanika iz 65 obitelji koje nisu
u međusobnom krvnom srodstvu sa sumnjom na talasemiju. Analizirani su hematološki i
biokemijski parametri. Molekularno-genetička analiza globinskih gena provedena je metodama
lančane reakcije polimerazom i sekvenciranja po Sangeru. Procjena težine talasemijskog
fenotipa je učinjena Mahidol sustavom bodovanja. U statističkoj obradi podataka korišten je
Mann-Whitney U-test.
Rezultati: Heterozigotni β-talasemijski sindrom je otkriven u 30 ispitanika i njihovih 16 prvih
srodnika u 24 obitelji iz Hrvatskog primorja i Istre koje nisu u međusobnom krvnom srodstvu.
U svih ispitanika utvrđena je mikrocitoza i hipokromija, a u 60,0% i blaga anemija. Hemoglobin
(Hb) F je bio povišen u 75,0%, a HbA2 u 60,7% ispitanika. Specifični genotipski profil u
populaciji Hrvatskog primorja i Istre čini devet uzročnih varijanti, od kojih na pet varijanti
otpada 83,2%: Hb Lepore Boston-Washington (BW), β+ IVS-I-110, β0 IVS-II-1, β0 IVS-I-1 i β+
IVS-I-6. Najčešće uzročne varijante su pretežito mediteranskog podrijetla i većinom se
podudaraju s varijantama opisanim u susjednim populacijama Mediterana i Balkana. Nisu
otkrivene nove varijante. Svi ispitanici su imali blagi oblik talasemije. Postoji dobra korelacija
genotipa i fenotipa. U ispitanika s istim genotipom i varijabilnim biokemijskim fenotipom (HbF
>5%) otkrivena je prisutnost XmnI polimorfizma, kao potencijalnog sekundarnog
modifikatora. Niti jedan ispitanik nije bio nositelj α-talasemijske varijante.
Zaključak: Molekularno-genetičko testiranje ima sve veći značaj u postavljanju precizne
dijagnoze talasemijskih sindroma, otkrivanju statusa nositelja, genetičkom savjetovanju, izradi
preventivnih programa, definiranju terapijskih ciljeva i razvoju javnozdravstvenih mjera.
Vrijedno je nastaviti istraživanja na molekularnoj karakterizaciji uzročnih varijanti β
talasemijskih sindroma na području cijele Hrvatske.Objectives: To investigate the causal variants of thalassemia syndromes in the population of the
Croatian Littoral and Istria, and compare the findings with other populations. The specific aims
are to analyze the hematological, biochemical, and clinical features in individuals with
thalassemia syndromes, to determine the correlation between genotype and phenotype, and to
design the algorithm for molecular-genetic diagnosis of thalassemia.
Material and Methods: The cross-sectional study included 112 participants from 65 unrelated
families with suspected thalassemia. Hematological and biochemical parameters were
analyzed. Molecular-genetic analysis of the globin genes was performed using polymerase
chain reaction and Sanger sequencing. The assessment of thalassemic phenotype was performed
according to Mahidol scoring system. The Mann-Whitney U-test was used for statistical data
processing.
Results: Heterozygous β-thalassemia syndrome was identified in 30 participants and their 16
first-degree relatives from 24 unrelated families from the Croatian Littoral and Istria.
Microcytosis and hypochromia were observed in all subjects, with mild anemia present in 60%.
Hemoglobin (Hb) F was elevated in 75,0%, and HbA2 in 60,7% of subjects. The specific
genotype profile in the population of the Croatian Littoral and Istria consists of nine causal
variants, five of which account for 83.2%: Hb Lepore Boston-Washington (BW), β+ IVS-I-110,
β0 IVS-II-1, β0 IVS-I-1, and β+ IVS-I-6. The most frequent causal variants are predominantly
of Mediterranean origin and largely overlap with variants reported in neighboring
Mediterranean and Balkan populations. No new variants were detected. All participants had a
mild type of disease. There is a good correlation between genotype and phenotype. In subjects
with the same genotype and a variable biochemical phenotype (HbF >5%), the presence of the
XmnI polymorphism was detected as a potential secondary modifier. None α-thalassemia
carrier was identified.
Conclusion: Molecular-genetic testing is increasingly important for the precise diagnosis of
thalassemia syndromes, detection of carriers, genetic counseling, the development of preventive
strategies, setting therapeutic goals, and the implementation of public health programs. It is
worth to continue research on the molecular characterization of causal variants of β-thalassemia
syndromes in the Croatian population
Challenges of Employer Branding in the Health Sector
Zdravstveni sektor suočava se s jedinstvenim izazovima kada je u pitanju privlačenje i
zadržavanje stručnjaka, kao što su medicinsko osoblje, liječnici, medicinske sestre, tehničari i
ostali zdravstveni i nezdravstveni radnici. S obzirom na sve veći nedostatak kvalificiranog
osoblja u ovom sektoru, ključno je razumjeti kako poslodavci mogu iskoristiti strategije
brendiranja kako bi se istaknuli kao poželjni poslodavci. Zdravstveni sektor prolazi kroz brze
promjene, uključujući tehnološke inovacije, demografske promjene i promjene u očekivanjima
pacijenata. Ove promjene zahtijevaju nove pristupe u upravljanju ljudskim resursima,
uključujući brendiranje poslodavaca kako bi privukli i zadržali visoko kvalificirane
zdravstvene stručnjake. Stoga je istraživanje izazova brendiranja poslodavaca u zdravstvenom
sektoru relevantno i važno za razumijevanje strategija koje poslodavci mogu primijeniti kako
bi ostali konkurentni i privukli najbolje talente u industriji. Predmet istraživanja proizlazi iz
sve veće važnosti koju ima brendiranje u privlačenju i zadržavanju kvalitetnih kadrova u
zdravstvenoj industriji. Uspješno brendiranje može imati značajan utjecaj na privlačenje
talentiranih stručnjaka, izgradnju povjerenja pacijenata i postizanje konkurentske prednosti u
dinamičnom okruženju zdravstvene industrije. Stoga je važno da zdravstvene ustanove
prepoznaju ove izazove i posvete se razvoju snažnog i autentičnog brenda koji odražava
njihove vrijednosti, kvalitetu i posvećenost pacijentima i stručnjacima.The healthcare sector faces unique challenges when it comes to attracting and retaining
professionals, such as medical staff, doctors, nurses, technicians and other healthcare and nonhealthcare professionals. Given the increasing shortage of skilled personnel in this sector, it is
crucial to understand how employers can leverage branding strategies to stand out as preferred
employers. The healthcare sector is undergoing rapid changes, including technological
innovation, demographic changes and changes in patient expectations. These changes require
new approaches to human resource management, including employer branding to attract and
retain highly qualified healthcare professionals. Therefore, research into employer branding
challenges in the healthcare sector is relevant and important to understanding the strategies
employers can employ to remain competitive and attract the best talent in the industry. The
subject of the research stems from the increasing importance of branding in attracting and
retaining quality staff in the healthcare industry. Successful branding can have a significant
impact on attracting talented professionals, building patient trust and achieving competitive
advantage in the dynamic environment of the healthcare industry. It is therefore important that
healthcare institutions recognize these challenges and commit to developing a strong and
authentic brand that reflects their values, quality and commitment to patients and
professionals
Business models and firm performance in food service industry
Pojam poslovni model u ekonomskoj, posebice menadžerskoj literaturi sve se češće spominje, a u zadnjih 20-tak godina istraživanja na tom području prilično su intenzivirana. Autori kontinuirano analiziraju značenje poslovnih modela za poslovanje, povezanost strategije poslovanja s poslovnim modelima i nastoje identificirati ključne elemente poslovnih modela primjerima iz različitih gospodarskih djelatnosti. Interes za istraživanja na temu poslovnih modela prilično je velik, no još uvijek nema dovoljno istraživanja koja se odnose na turistički sektor i ugostiteljsku djelatnost, a pogotovo radova koji povezuju poslovni model i uspješnost poslovanja. U doktorskom radu prikazan je teorijski pregled razvoja poslovnih modela i njegovih elemenata, kako općenito tako i u kontekstu turizma i ugostiteljstva. Osim navedenoga, utvrdile su se karakteristike poslovnih modela poduzeća koja posluju u djelatnosti pružanja usluga pripreme i usluživanja hrane i pića te je istražena veza između poslovnoga modela i uspješnosti poslovanja poduzeća u djelatnostima pripreme i usluživanja hrane i pića. Empirijsko istraživanje provedeno je korištenjem primarnih podataka dobivenih analizom anketnih upitnika upućenih vlasnicima poduzeća u djelatnosti pružanja usluga hrane i pića u hrvatskom ugostiteljstvu te analizom dostupnih sekundarnih podataka. Rezultati su istraživanja pokazali da je u hrvatskom ugostiteljstvu moguće izdvojiti više različitih poslovnih modela. Identificirani poslovni modeli jesu: restorani sa širokom ponudom jela koji rade cijele godine, sezonski restorani sa širokom ponudom jela, restorani sa širokom ponudom jela i dodatnom uslugom koji rade cijelu godinu, restorani s uskom ponudom jela i dodatnim takeaway uslugama i uslugama dostave koji rade cijelu godinu i restorani s širokom ponudom jela, dodatnom uslugom cateringa koji rade cijelu godinu. Uz identificirane poslovne modele, dobiveni su i rezultati koji impliciraju kako su poslovni modeli s izuzetno izraženom komponentom dodatne usluge dostave i takeaway usluge uspješniji od ostalih. Nadalje, rezultati istraživanja impliciraju da poslovni modeli s implementiranim elementima poslovnoga modela limitirane ponude, dodatne usluge dostave i usluge takeaway ostvaruju bolje financijske rezultate. Originalnost rada prepoznaje se u činjenici da se istraživanja poslovnih modela s fokusom na ugostiteljstvo i segment pružanja hrane i pića ne provode dovoljno u Republici Hrvatskoj, a ni u svijetu. Teorijski doprinos istraživanja proizlazi iz teorijske analize karakteristika poslovnih modela u turizmu i ugostiteljstvu s naglaskom na djelatnost pripreme i usluživanja hrane i pića. U kontekstu ugostiteljskoga poslovanja nema dovoljno istraživanja koja definiraju elemente poslovnih modela poduzeća, koja djeluju u ugostiteljstvu u djelatnosti pripreme i usluživanja hrane i pića. Isto tako, nema dovoljno istraživanja u kojima se stavlja u odnos dizajn poslovnoga modela ugostiteljskoga poduzeća s rezultatima njegova financijskog poslovanja. U ovom radu identificirani su elementi poslovnih modela ugostiteljskih poduzeća, prikazani su različiti poslovni modeli poduzeća u ugostiteljskoj djelatnosti te su identificirane specifičnosti poslovnih modela u segmentu poduzeća koja djeluju u ugostiteljstvu. Empirijski doprinos istraživanja proizlazi iz identificiranja različitih poslovnih modela poduzeća koja djeluju u djelatnosti pripreme i usluživanja hrane i pića te utvrđivanja veze između poslovnoga modela te uspješnosti poslovanja poduzeća u djelatnosti pripreme i usluživanja hrane i pića. Sličan pristup istraživanju identificiran je samo u jednom radu i to na području Rusije, koja obuhvaća prilično veliko tržište u odnosu na hrvatsko tržište te samim time na takvom tržištu moguće su, velike različitosti u poslovanju poduzeća. Također, Rusija nije toliko turistički orijentirana u smislu sezonskoga načina rada, kao što su zemlje poput Hrvatske, Španjolske, Turske, Grčke i drugih sličnih zemalja, pa ovaj rad sa zaključcima koji su proizašli iz empirijskog dijela istraživanja, značajan za zemlje sličnih gospodarskih prilika. Empirijski doprinos vidljiv je i u metodološkom pristupu kroz upotrebu klaster analize u svrhu identificiranja različitih poslovnih modela poduzeća u ugostiteljstvu, koji se može primijeniti i u budućim istraživanjima sličnoga tipa u sklopu neke druge djelatnosti te korištenjem drugih nezavisnih i zavisnih varijabli. Aplikativni doprinos istraživanja proizašao je iz identificiranja poslovnih modela i elemenata poslovnih modela za koje se utvrdilo da omogućuju bolji financijski rezultat. Rezultati istraživanja mogu se direktno primijeniti u poslovnim sustavima koji provode ugostiteljsku djelatnost pružanja usluga hrane i pića.When doing business, entrepreneurs are aware of numerous opportunities to achieve additional value by implementing various ideas in different business segments. Despite this, in practice, it has been shown that more than good ideas are needed to break through and compete in the market to achieve the desired goals. New participants are constantly entering the market whose business is based on different methods, new approaches, and new products, in other words, new business models to achieve the highest possible profit and sustainability on the market. Each company has its own business model and, depending on the design of the business model, achieves a particular position in the market and specific financial results.
The term business model is frequently used, especially in management literature, and in the last 20 years, the publication of papers in this field has intensified. The term itself has been perceived and defined in various ways, so there needs to be more consistency in its definition and interpretation. Also, the term has been defined and understood differently in various economic areas and thought history has been considered an essential construct in several research fields. The most frequently mentioned and used elements in research are value proposition, value creation, customers, resources, and revenues. Consistency in naming and using these terms is noticed only in the concept of the value achieved through the various activities of the company. In almost all research papers, the term value proposition is mentioned as a foundational and essential element of every business model. The authors continually analyse the significance of business models related to company performance and the relationship of business strategy and business models. They try to identify the key elements of business models by using examples from different economic activities. Although the interest in business model research is extensive, and numerous papers have already been published on this topic, not enough research is being done on the tourism or hospitality industry.
The purpose of this research was to determine various business model designs implemented by companies in the food and beverage industry and to find and identify correlations between different business models and the company´s financial performance. By analyzing business models and comparing a larger sample of firms operating in the hospitality industry, specifically in food and beverage service activities, the relationship between business model design and business performance in the hospitality industry is explored. This thesis presents a theoretical review of the development of business models and their elements, both in general and in the context of the tourism and hospitality industry.
The business model in the hospitality industry includes three key components: the operating model, which represents the way in which value is created for the company; the economic model, which includes income drivers and an approach to creating sales prices; and the strategic model, which defines the market and how to approach a company’s growth. Essential elements, with specific items singled out for companies dealing with preparing and serving food and drinks, are products, value creation and growth, and profit realization. The products that enter the operational dimension of the business refer to the breadth of the range of dishes in all categories of the offer. Value creation, also an operational component, refers to how the service is offered, whether ready or semi-ready meals are used or if meals are created on the spot; whether a full table service is provided or the guest serves themselves; and the possibility of delivering additional services such as the possibility of taking food outside the restaurant (take away), preparing food in the facility and serving services at another location (catering), and the possibility of delivering food (home delivery) to another location. Utilizing a model that contributes to achieving company growth and profit realization, the economic and strategic components of business determine whether the company will operate through one catering facility or several catering facilities, separately or in a chain, and from a geographical point of view, whether the facilities are local, regional or nationally oriented, and whether the company operates according to its own strategic framework or bases its business on a franchise agreement.
The analysis was performed on a sample of 147 companies in the Republic of Croatia operating within the food and beverage service industry. A cluster analysis was conducted to define specific groups of food and beverage companies with specific business elements and characteristics. The parametric t-test and the ANOVA method of linear modelling were used to explore the mutual relationship between a company’s business model and performance measures. The findings reveal statistically significant relationships between the variables used in the research based on the selected sample and the obtained clusters of companies. In addition, the characteristics of companies´ business models in the food service industry were determined, and the impact of individual business model designs on company performance was tested. Empirical research was carried out using primary data obtained by analyzing survey questionnaires addressed to the owners of the company providing food and beverage service activities and by analyzing available secondary data.
The findings proved that, in the Croatian hospitality industry, there is a possibility of singling out several different business models. The identified designs of business models include: “Restaurants with a wide range of dishes that operate all year round,” “Seasonal restaurants with a wide range of dishes,” “Restaurants with a wide range of dishes and additional services that operate all year round,” “Restaurants with a narrow range of dishes, additional services take away and food delivery, that operate the whole year,” and “Restaurants with a wide range of dishes, with an additional catering service that works all year round.” It was also found that there is a difference between individual elements of business models and financial business performance. Accordingly, companies with a business model that includes additional services for food delivery, takeaway, or limited offers of food and beverages achieve better financial performance.
The theoretical contribution of this research is observed through the theoretical analysis of the characteristics and business model designs in the tourism and hospitality industry with an emphasis on food and beverage services. Authors who previously researched this field state in their conclusions that it would be desirable to conduct additional research and consider companies that are more similar in their business model and are operating in the same field to gain a better understanding of the topic. Only when this is achieved could better conclusions be drawn about the impact of business models on company operations because the results obtained so far are too generalized. The theoretical contribution is also visible in the methodological approach. The use of cluster analysis for the purpose of identifying different designs of business models of companies in the hospitality industry can be replicated in future research of a similar type within another industry and by using other independent and dependent variables.
The contribution of empirical research results from the determination of different business models of companies that operate in the food and beverage service industry and identifying the correlation between the design of the business model and the financial performance of the company.
The applicable contribution of the research is reflected in the identified business models and elements of business models that have been found to enable better financial performance. Companies that can identify the key elements of their business in time, implement their business model, and find new ways in which they can continuously innovate will be able to understand better and utilize the possibilities for adapting as quickly as possible to a dynamic and challenging market.
The originality of this thesis is recognizable in the fact that research on business models focused on providing food and beverage service activities has not been explored to a sufficient extent, neither in the Republic of Croatia nor internationally
Informatizacija i administracija u primaljstvu : priručnik za studente/ice sveučilišnog prijediplomskog studija Primaljstvo
Razvoj informacijsko-komunikacijske tehnologije (IKT) ima sve značajniju ulogu u različitim segmentima zdravstvene skrbi, uključujući i primaljstvo (1). Primjena IKT-a utječe na transformaciju kliničke i administrativne prakse, čime se poboljšava kvaliteta zdravstvene skrbi (2). Uvođenje zdravstvenih informacijskih sustava (ZIS) u primaljstvo ima brojne prednosti, a vodeća je brzi pristup zdravstvenim podatcima. Središnji dio informatizacije u primaljstvu predstavlja upravljanje elektroničkim zdravstvenim zapisom (EZZ) u kojem su zabilježeni svi podatci vezani za trudnoću, porod i postnatalnu skrb (3). Primalje, kao ključni akteri u skrbi za žene i novorođenčad, sve više preuzimaju aktivnu ulogu u upravljanju ZIS-om, a njihova osposobljenost za rad s digitalnim alatima postaje ključna kompetencija (4). Korištenje specijaliziranih programskih rješenja olakšava im vođenje registra poroda, praćenje i izdavanje medicinske dokumentacije, te izvještavanje o ishodima liječenja, dok automatizacija ovih procesa smanjuje mogućnost pogrešaka (5). Informatizacija također omogućava praćenje ishoda trudnoće i poroda, sistematizirajući podatke o majčinskoj i neonatalnoj skrbi, što može poslužiti kao temelj za unaprjeđenje zdravstvene politike i prakse. Osim toga, ZIS poboljšava kontrolu kvalitete usluga i identifikaciju potencijalnih problema, omogućujući prilagodbu procedura za bolju zdravstvenu skrb. S obzirom na sve veći utjecaj digitalizacije, kontinuirano usavršavanje i edukacija primalja postaju neophodni za unapređenje digitalnih kompetencija (6). Stoga, primjena IKT-a ne samo da optimizira kliničku praksu, nego značajno doprinosi sigurnijoj, bržoj i personaliziranoj skrbi za majke i novorođenčad. Primalje osim što stječu nove kompetencije i preuzimaju aktivnu ulogu u upravljanju informacijama, također postaju i važni dionici u procesu digitalne transformacije zdravstva i zdravstvene skrbi (7)
Exploiting the Potential of Social Networks by Family Farms in Croatia
Family farms account for more than half of all registered agricultural entities in Croatia,
making them essential not only for rural development but also for the economy. However,
there is no unified, free platform for family farms to market their products and connect with
consumers, leading to a market gap that social networks can help bridge. This chapter
analyzes the Facebook pages of family farms across Croatia to determine the interrelation of
the number of social networks the farm is active on and the diversity of posts on Facebook
with the number of "likes" and follower engagement (reactions, comments, and shares on the
last ten posts). The results indicate that the number of social networks brings about only an
increase in the number of "likes", while the diversity in Facebook posts attracts both more
"likes" and greater follower engagement. The findings also point to the family farms’
underutilization of the social network potential in relation to sharing essential information
(location, main activity), brand development and promotion of family farms from specific
regions and trades. Family farms should thus put more effort into social networking. They
should offer delivery through these channels, increase posting frequency, and collaborate with
social media influencers
PATERNITY AND MATERNITY DISPUTES: PECULIARITIES IN RELATION TO REGULAR CIVIL PROCEEDINGS
Redovan parnični postupak je osnovan način na koji osoba može zaštititi svoja građanska prava. Njegova osnovna načela čine okosnicu svih vrsta parničnih sporova.
Paternitetski i maternitetski sporovi, u kojima se odlučuje o utvrđivanju ili osporavanju očinstva odnosno majčinstva, obiluju mnogim posebnostima u odnosu na redovan parnični postupak. Posebnosti paternitetskih i maternitetskih sporova proizlaze prije svega iz potrebe zaštite djece i osoba koje nisu u stanju same se brinuti za svoja prava i interese.Razlike se pritom očituju u načelima poput načela javnosti i načela hitnosti, ograničenju dispozicije stranaka itd.
U pravilu se u mnogim elementima paternitetskog i maternitetskog postupka mogu uočiti veće ili manje razlike u odnosu na redovan parnični postupak.General civil procedure is an established way for a person to protect his civil rights. It`s main principles form the basis of all types of civil disputes. Paternity and maternity disputes, in which it is decided to establish or dispute paternity or maternity, have many peculiarities compared to regular civil proceedings.
The peculiarities of paternity and maternity disputes stem primarily from the need to protect children and persons who are unable to take care of their rights and interests on their own. The differences are manifested in principles such as the principle of publicity and the principle of urgency, courts have greater control in some questions etc.
In many elements of paternity and maternity disputes differences can be noticed compared to general civil procedure
Green Shipping Corridors: A Bibliometric Analysis of Policy, Technology, and Stakeholder Collaboration
This study provides a bibliometric review of 238 studies on the concept of green shipping corridors in the maritime industry, published in 93 academic outlets and authored by 654 scholars. Bibliographical data were extracted from the Web of Science database and analyzed using the bibliometrix package in R software (version 4.3.3) alongside VOSviewer (version 1.6.20). Based on citation analysis metrics, the most influential articles, journals, authors, institutions, and countries within the field were identified. Utilizing the bibliographic coupling methodology in VOSviewer, the following four underlying research clusters were distinguished: (1) Sustainable Green Shipping Practices and Research, (2) Alternative Fuels and Low-Carbon Strategies for Maritime Transport, (3) Green and Low-Carbon Maritime Development, and (4) Environmental Sustainability in Maritime Shipping. Content analysis results highlighted crucial policy recommendations, technological adaptation strategies, and collaborative stakeholder practices, providing robust insights for academia and industry practitioners seeking strategic guidance for effective maritime decarbonization via integrated green shipping corridor initiatives
Information and Communication Technology, and Supply Chains as Economic Drivers in the European Union
Background: The adoption of information and communication technology (ICT) is transforming supply chains in the European Union, affecting logistical performance, economic integration and sustainability. This study examines the extent to which ICT adoption affects logistics efficiency in the 27 EU Member States. Methods: Using panel data from the World Bank and UNCTAD (2008–2018), the analysis applies the Arellano–Bond Generalized Method of Moments estimator to assess the impact of ICT indicators, broadband penetration, mobile connectivity and digital skills on logistics performance. GDP per capita and trade openness are included as control variables. Results: The results show that a 1% increase in ICT usage correlates with a 0.12-point increase in the Logistics Performance Index. Higher ICT usage leads to more efficient supply chains, lower costs and higher customer satisfaction. However, there are still differences in digitalization: the ICT usage rate of SMEs is 28% in Bulgaria and 27% in Romania, compared to the EU average of 59%. Conclusions: Bridging the digital divide requires targeted investments in ICT infrastructure, harmonized regulatory frameworks and stronger public–private cooperation to foster regional economic cohesion. This study provides policy recommendations to drive digital transformation, strengthen the resilience of logistics and improve the sustainability of supply chains in the EU