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Corrigendum to “Understanding the barriers to plant-based dietary change: The role of meat-centric meal perception among adults in Australia and Denmark” [Appetite Volume 215 (2025) 108240]
No full textCorrigendum to “Understanding the barriers to plant-based dietary change: The role of meat-centric meal perception among adults in Australia and Denmark” [Appetite Volume 215 (2025) 108240
The Role of Adaptive and Innovative Trial Designs in Diabetes Research: A Scoping Review
No full textBACKGROUND
Adaptive and master protocol clinical trials offer significant advantages for diabetes research, including enhanced efficiency and personalized treatment strategies.
PURPOSE
This scoping review aimed to systematically map the use of adaptive and master protocol designs in interventional trials for type 1 and type 2 diabetes, identify research gaps, and highlight opportunities for broader implementation.
DATA SOURCES
A systematic literature search was performed using MEDLINE, Embase, CENTRAL, Emcare, Global Health, Web of Science, and clinical trial registries. Gray literature searches complemented database findings.
STUDY SELECTION
Studies using adaptive, platform, basket, or umbrella trial designs in people with type 1 or type 2 diabetes were included.
DATA EXTRACTION
Data were charted using a standardized form. Extracted variables included diabetes type, trial design, adaptive features, interventions, end points, and key findings.
DATA SYNTHESIS
Of 396 articles screened, 6 published adaptive trials met the inclusion criteria: 3 in type 1 diabetes, 1 in type 2 diabetes, and 2 in diabetes-related neuropathy. Most used adaptive features for dose finding, response-adaptive randomization, and sample size reestimation. No published platform, basket, or umbrella trials were identified. Six ongoing adaptive trials in type 1 diabetes were identified through registry searches, four under an adaptive platform master protocol.
LIMITATIONS
Despite a comprehensive search, some gray literature and unpublished studies may have been missed. Risk of bias was not assessed, consistent with scoping review methodology.
CONCLUSIONS
Adaptive and master protocol trials remain rare in diabetes. Overcoming barriers through targeted training and awareness, robust regulatory frameworks, and strategic incentives could support broader adoption
Learning from the omicron BA.4/5 dominance: Strategies for future vaccination preparedness
No full textLearning from the omicron BA.4/5 dominance: Strategies for future vaccination preparedness</p
Collecting protest event data using natural language processing models
No full textCollecting protest event data using natural language processing models</p
Additive Manufacturing Teaching and Training Case Studies: Education Strategies for Additive Manufacturing
No full textAdditive Manufacturing Teaching and Training Case Studies: Education Strategies for Additive Manufacturing</p
Experimental Evidence of Changing Habitat Use and Activity of Native Prey During Invasive Mesopredator Population Control
No full textABSTRACT
Predators can alter the habitat use and temporal activity patterns of prey, impacting their vital rates. Such dynamics between species are critical to understand in relation to invasive predators, which are among the greatest threats to biodiversity. In response to invasive predator impacts, predator‐free “safe havens” are increasingly being used to prevent the loss of threatened wildlife species. Few studies have experimentally tested how prey behavior may change in relation to invasive predator population control programs and habitat variation. We investigated changes in the foraging behavior and activity of two ground‐dwelling, threatened marsupial species during a feral cat eradication program and in relation to more open versus more closed vegetation. We used giving‐up density stations and motion‐triggered cameras to record foraging behavior and the perceived risk of prey before and during a feral cat eradication program, and across a gradient of low to high vegetation density on French Island, south‐eastern Australia. After feral cat population reduction, each species used both open and closed vegetation more frequently, with foraging behavior (lower giving‐up densities) and activity increasing over time. Our results suggest bandicoots and potoroos recognize feral cats as a threat, and that they modify their spatial and temporal activity accordingly. More broadly, this suggests that substantial benefits of cat eradication programs—including native prey being able to occupy and use more habitat—can be realized relatively quickly and before the ultimate, longer‐term goal of cat eradication is achieved.</p
Gender and Protest: What Do ‘Nasty Women’ Want? Human Rights, Then and Now!
No full textGender and Protest: What Do ‘Nasty Women’ Want? Human Rights, Then and Now
Beta-Band Modulation Reveals the Cortical Dynamics of Auditory Statistical Learning in Children
No full textBeta-Band Modulation Reveals the Cortical Dynamics of Auditory Statistical Learning in Childre
Mechanistic insights into cellulose dissolution in deep eutectic solvents from classical MD simulations
No full textMechanistic insights into cellulose dissolution in deep eutectic solvents from classical MD simulation