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Radioprotective effects of Dragon's blood and its extract against gamma irradiation in mouse bone marrow cells
Purpose: The radioprotective effects of Dragon's blood ( DB) and its extracts (DBE) were investigated using the chromosomal aberrant test, micronucleus and oxidative stress assay for anti-clastogenic and anti-oxidative activity. Materials and methods: Adult BALB/C mice were exposed to the whole body irradiation with 4 Gy Co-60 gamma rays. DB and DBE were administered orally once a day from 5 days prior to irradiation treatment to 1 day after irradiation. The mice were sacrificed on 24 h after irradiation. The cells of bone marrow were measured by counting different types of chromosomal aberrations and the frequency of micronuclei. Oxidative stress response was carried out by analysis of serum from blood. Results: DB and DBE significantly decreased the number of bone marrow cells with chromosome aberrations after irradiation with respect to irradiated alone group. The administration of DB and DBE also significantly reduced the frequencies of micronucleated polychromatic erythrocytes ( MPCE) and micronucleated normochromatic erythrocytes ( MNCE). In addition, DB and DBE markedly increased the activity of antioxidant enzymes and the level of antioxidant molecular. Malondialdehyde ( MDA) and nitric oxide ( NO) levels in serum were significantly reduced by DB and DBE treatment. Conclusions: Our data suggested that DB and DBE have potential radioprotective properties in mouse bone marrow after Co-60 gamma-ray exposure, which support their candidature as a potential radioprotective agent. (c) 2013 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved
电子-离子对撞机上开展核子及其激发态研究的建议
<span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);">核子及其激发态性质研究一直是中高能核物理的一个重要研究领域。然而,到目前为止,对核子及其激发态内部结构的了解还处在初级阶段。首先介绍了核子及其激发态研究现状,指出了三夸克模型在描述核子特别是核子激发态内部结构方面存在很大的缺陷。为解决传统三夸克模型的不足,有一种新的观点认为虽然独立的五夸克态不存在,但是核子及其共振态中存在可观的五夸克激发。这种五夸克图像提供了一个描述核子内部结构的新见解,给出了与经典三夸克图像相当不同的核子激发态谱预言,还有待实验检验。目前国内外正在论证的电子-离子对撞机(EIC)将是研究核子结构下一代最重要的加速器装置,被视为超级电子显微镜。由于EIC有较高的能量和亮度,特别是低本底等优势,可以开展核子及其激发态性质的研究以及新强子态研究。</span><span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);">The study of the properties of the nucleon and nucleon resonances is an important field in the high and intermediate energy nuclear physics, however, until now, our understanding about the structure of the nucleon and nucleon resonances is still in its infancy. We give a brief review on the current researches of the nucleon and nucleon resonances, and point out that the classical quark model can not successfully describe the structure of the nucleon and nucleon resonances. For doing this, a new idea claims that although the five-quark state does not exist, but, there could be significant five-quark components in the nucleon and nucleon resonances. This five-quark configure gives different predictions for the nucleon resonances which will be tested by the future experiments. Now, the proposed Electron-Ion Collider (EIC) will be the most important accelerator installation for studying the nucleon structure, and it is called super-electronic-microscope. Because of the high energy and luminosity, and also low background, we can study the properties of the nucleon and nucleon resonances and new hadron states on EIC.</span
Progress of superconducting electron cyclotron resonance ion sources at Institute of Modern Physics (IMP)
<span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);">Superconducting ECR ion sources can produce intense highly charged ion beams for the application in heavy ion accelerators. Superconducting Electron Resonance ion source with Advanced Design (SECRAL) is one of the few fully superconducting ECR ion sources that has been successfully built and put into routine operation for years. With enormous efforts and R&D work, promising results have been achieved with the ion source. Heated by the microwave power from a 7 kW/24 GHz gyrotron microwave generator, very intense highly charged gaseous ion beams have been produced, such as 455 e mu A Xe27+, 236 e mu A Xe30+, and 64 e mu A Xe35+. Since heavy metallic ion beams are being more and more attractive and important for many accelerator projects globally, intensive studies have been made to produce highly charged heavy metal ion beams, such as those from bismuth and uranium. Recently, 420 e mu A Bi30+ and 202 e mu A U33+ have been produced with SECRAL source. This paper will present the latest results with SECRAL, and the operation status will be discussed as well. An introduction of recently started SECRAL II project will also be given in the presentation. (C) 2013 AIP Publishing LLC.</span
A 2.45 GHz intense proton source and low energy beam transport system for China Initiative Accelerator Driven Sub-Critical reactor system
Discharge characteristics of the DUHOCAMIS with a high magnetic bottle-shaped field
<span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);">For the purpose of producing high intensity, multiply charged metal ion beams, the dual hollow cathode ion source for metal ions (DUHOCAMIS) was derived from the hot cathode Penning ion source combined with the hollow cathode sputtering experiments in 2007. To investigate the behavior of this discharge geometry in a stronger magnetic bottle-shaped field, a new test bench for DUHOCAMIS with a high magnetic bottle-shaped field up to 0.6 T has been set up at the Peking University. The experiments with magnetic fields from 0.13 T to 0.52 T have indicated that the discharge behavior is very sensitive to the magnetic flux densities. The slope of discharge curves in a very wide range can be controlled by changing the magnetic field as well as regulated by adjusting the cathode heating power; the production of metallic ions would be much greater than gas ions with the increased magnetic flux density; and the magnetic field has a much higher influence on the DHCD mode than on the PIG mode.</span
Study of Borromean halo nuclei by the neutron wall with simulation
<span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);">The model of three-body Borromean halo nuclei breakup was described by using standard phase space distributions and the Monte Carlo simulation method was established to resolve the detection problem of two neutrons produced from breakup reaction on the neutron wall detector. For He-6 case, overall resolution sigma(Ek) for the Gaussian part of the detector response and the detection efficiency including solid angle acceptance with regard to the excitation energy E-k are obtained by the simulation of two neutrons from He-6 breakup into the neutron wall. The effects of the algorithm on the angular and energy correlations of the fragments are briefly discussed.</span
X-ray spectrum emitted by the impact of 152Eu20+ of near Bohn velocity on Au surface
<span class="hitHilite" style="margin: 0px; list-style: none; padding: 0px; color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(255, 255, 0);">The</span><span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);"> characteristic </span><span class="hitHilite" style="margin: 0px; list-style: none; padding: 0px; color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(255, 255, 0);">X-ray</span><span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);"> spectra produced </span><span class="hitHilite" style="margin: 0px; list-style: none; padding: 0px; color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(255, 255, 0);">by</span><span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);"> </span><span class="hitHilite" style="margin: 0px; list-style: none; padding: 0px; color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(255, 255, 0);">the</span><span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);"> </span><span class="hitHilite" style="margin: 0px; list-style: none; padding: 0px; color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(255, 255, 0);">impact</span><span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);"> </span><span class="hitHilite" style="margin: 0px; list-style: none; padding: 0px; color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(255, 255, 0);">of</span><span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);"> highly charged ions </span><span class="hitHilite" style="margin: 0px; list-style: none; padding: 0px; color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(255, 255, 0);">of</span><span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);"> Eu-152(20+) with energies from 2.0 to 6.0 MeV </span><span class="hitHilite" style="margin: 0px; list-style: none; padding: 0px; color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(255, 255, 0);">on</span><span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);"> </span><span class="hitHilite" style="margin: 0px; list-style: none; padding: 0px; color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(255, 255, 0);">Au</span><span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);"> </span><span class="hitHilite" style="margin: 0px; list-style: none; padding: 0px; color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(255, 255, 0);">surface</span><span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);"> are measured. It is found that highly charged ions could excite both </span><span class="hitHilite" style="margin: 0px; list-style: none; padding: 0px; color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(255, 255, 0);">the</span><span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);"> characteristic </span><span class="hitHilite" style="margin: 0px; list-style: none; padding: 0px; color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(255, 255, 0);">X-ray</span><span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);"> spectra </span><span class="hitHilite" style="margin: 0px; list-style: none; padding: 0px; color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(255, 255, 0);">of</span><span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);"> M-zeta, M-alpha and M-delta </span><span class="hitHilite" style="margin: 0px; list-style: none; padding: 0px; color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(255, 255, 0);">of</span><span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);"> </span><span class="hitHilite" style="margin: 0px; list-style: none; padding: 0px; color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(255, 255, 0);">Au</span><span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);"> and </span><span class="hitHilite" style="margin: 0px; list-style: none; padding: 0px; color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(255, 255, 0);">the</span><span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);"> characteristic </span><span class="hitHilite" style="margin: 0px; list-style: none; padding: 0px; color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(255, 255, 0);">X-ray</span><span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);"> spectra </span><span class="hitHilite" style="margin: 0px; list-style: none; padding: 0px; color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(255, 255, 0);">of</span><span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);"> M-alpha </span><span class="hitHilite" style="margin: 0px; list-style: none; padding: 0px; color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(255, 255, 0);">of</span><span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);">Eu. </span><span class="hitHilite" style="margin: 0px; list-style: none; padding: 0px; color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(255, 255, 0);">The</span><span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);"> total </span><span class="hitHilite" style="margin: 0px; list-style: none; padding: 0px; color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(255, 255, 0);">X-ray</span><span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);"> yield increases with </span><span class="hitHilite" style="margin: 0px; list-style: none; padding: 0px; color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(255, 255, 0);">the</span><span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);"> ion kinetic energy increasing. </span><span class="hitHilite" style="margin: 0px; list-style: none; padding: 0px; color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(255, 255, 0);">The</span><span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);"> total production cross section </span><span class="hitHilite" style="margin: 0px; list-style: none; padding: 0px; color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(255, 255, 0);">of</span><span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);"> </span><span class="hitHilite" style="margin: 0px; list-style: none; padding: 0px; color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(255, 255, 0);">Au</span><span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);"> induced </span><span class="hitHilite" style="margin: 0px; list-style: none; padding: 0px; color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(255, 255, 0);">by</span><span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);"> Eu20+ is measured and compared with those obtained from </span><span class="hitHilite" style="margin: 0px; list-style: none; padding: 0px; color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(255, 255, 0);">the</span><span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);"> binary encounter approximation, plane-wave-Born approximation, and </span><span class="hitHilite" style="margin: 0px; list-style: none; padding: 0px; color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(255, 255, 0);">the</span><span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);"> energy-loss Coulomb deflection perturbed stationary state </span
Design of the extraction system of heavy ion medical cyclotron
<span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);">A compact cyclotron as the injector of a synchrotron which forms the heavy ion medical machine is being designed and constructed at Institute of Modern Physics, China. The required high intensity and high beam quality of the extraction beam make it difficult to design the extraction system. The magnetic field used in the design is calculated from TOSCA model. The single particle orbit is calculated to determine component types and basic parameters of the extraction system. The multi-particle tracking is done to determine the final component parameters and beam parameters. In order to improve the efficiency and beam quality of the extraction system, a C-type magnet is placed at the location, where the magnetic field gradient is very large. A pair of coil is used to eliminate the effect of the C-type magnet on the main magnetic field. Detailed calculations show the extraction beam intensity and beam quality can meet the requirement of the synchrotron.</span