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経口摂取した寒天由来アガロオリゴ糖の血中移行に関する研究
Get PDF信州大学(Shinshu university)博士（農学）この博士論文は、次の学術雑誌論文を一部に使用しています。 / Frontiers in Nutrition 9 :996607(2022); doi:10.3389/fnut.2022.996607 © 2022 Shirai, Karasawa, Kodaira, Iwasaki, Shigemura, Makabe and Katayama. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms./ Frontiers in Nutrition 10 :1273328(2023); doi:10.3389/fnut.2023.1273328 © 2023 Shirai, Iwasaki, Karasawa, Shigemura and Katayama. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.Thesis白井 郁也. 経口摂取した寒天由来アガロオリゴ糖の血中移行に関する研究. 信州大学, 2024, 博士論文. 博士（農学）, 甲第105号, 令和06年03月20日授与.doctoral thesi
新卒社会人のリアリティ・ショックが職業性ストレスへ及ぼす影響
Get PDF新卒社会人のストレス反応にリアリティ・ショック(RS)が与える影響および個人の過剰適応度と切り替え能力との関連を明らかにすることを目的とした。新卒3年目までの社会人122名を対象にWebにて質問紙調査を実施した。その結果，対象者の半数が離職を検討したことがあること，RSは職場ストレッサーから心理的ストレスへの影響を媒介・促進すること，個人要因としての切り替え能力が職場ストレッサーから心理的ストレスへの直接効果を弱める可能性が示唆された。Article信州心理臨床紀要 23 : 50-62, (2024)departmental bulletin pape
Ecoenzymatic stoichiometry as a temporally integrated indicator of nutrient availability in soils
Get PDFThe extent to which soil enzyme activity in assessing soil nutrient availability is useful has been controversial. In this review, we discuss the utility of ecoenzymatic stoichiometry (i.e. the ratio of nutrient- to carbon (C)-acquiring enzyme activities) on the basis of the resource allocation model for ecoenzyme synthesis. Both the selection of appropriate enzymes and the balance between relative amounts of substrates and enzymes in the soil are decisive factors in utilizing the ecoenzymatic stoichiometry. Ecoenzymatic stoichiometry can evaluate the availability of nitrogen (N), phosphorus, and sulfur in many soils in which the enzyme catalytic reactions are substrate-limited but not enzyme-limited. However, the ecoenzymatic stoichiometry approach does not seem to be applicable in soils where microbes are limited by factors other than nutrient availability, such as low temperature, where the enzyme catalytic reactions are enzyme-limited. Certain enzymes, such as N-acetyl-β-glucosaminidase and protease, appear to be insensitive to soil N availability, because they release compounds containing both N and C which serve as sources for both N and C/energy. We propose the use of enzymes such as L-asparaginase and urease as N-acquiring enzymes that release a compound containing N but not C (i.e. NH4+) as the hydrolysis product. Ecoenzymatic stoichiometry can be considered as an indicator of long-term (weeks) temporally integrated soil nutrient availability, rather than instantaneous availability, for plants as well as microbes, because of (i) the long-term persistence of extracellular enzymes in soils; (ii) a significant correlation between ecoenzymatic stoichiometry and the measurements reflecting the quantity of long-term available nutrients in soil; and (iii) a significant correlation between ecoenzymatic stoichiometry and plant nutrient uptake. This review also identifies challenges in assessing microbial nutrient limitation using ecoenzymatic stoichiometry. With a comprehensive understanding of underlying mechanisms and limitations, ecoenzymatic stoichiometry can be used as a biologically relevant indicator of nutrient availability in combination with other approaches such as conventional chemical extraction methods and the nutrient addition approach.Ecoenzymatic stoichiometry as a temporally integrated indicator of nutrient availability in soils. Soil Science and Plant Nutrition, 70(4), 246–269. (2024)journal articl
Increased mitochondria are responsible for the acquisition of gemcitabine resistance in pancreatic cancer cell lines（膵癌細胞株におけるミトコンドリア増加はゲムシタビン耐性獲得に寄与する）
Get PDF信州大学(Shinshu university)博士（医学）次の雑誌に発表。 /Cancer Science 114(11) :4388-4400(2023); doi:10.1111/cas.15962 © 2023 The Authors. Cancer Science published by John Wiley & Sons Australia, Ltd on behalf of Japanese Cancer Association.Thesis増尾 仁志. Increased mitochondria are responsible for the acquisition of gemcitabine resistance in pancreatic cancer cell lines（膵癌細胞株におけるミトコンドリア増加はゲムシタビン耐性獲得に寄与する）. 信州大学, 2024, 博士論文. 博士（医学）, 甲第1368号, 令和06年03月31日授与.doctoral thesi
Symptom-based portopulmonary hypertension screening questionnaire in Japanese patients with chronic liver disease(日本人慢性肝疾患患者における症状ベースの門脈圧亢進症性肺高血圧症のスクリーニング)
Get PDF信州大学(Shinshu university)博士（医学）次の雑誌に発表。 /JGH Open 7(8) :527-536(2023); doi:10.1002/jgh3.12939 © 2023 The Authors. JGH Open published by Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd.Thesis若林 俊一. Symptom-based portopulmonary hypertension screening questionnaire in Japanese patients with chronic liver disease(日本人慢性肝疾患患者における症状ベースの門脈圧亢進症性肺高血圧症のスクリーニング). 信州大学, 2024, 博士論文. 博士（医学）, 甲第1375号, 令和06年03月31日授与.doctoral thesi
An optimal skeletal element for DNA testing: Evalution of DNA quantity and quality from various bone types in routine forensic practice （DNA鑑定のための最適な骨組織の部位の探索：法医実務において採取した、複数の種類の骨組織から抽出したDNAの質および量に基づいた検証）
Get PDF信州大学(Shinshu university)博士（医学）次の雑誌に発表。 /Legal Medicine 68 :102415(2024); doi:10.1016/j.legalmed.2024.102415 © 2024 The Author(s). Published by Elsevier B.V. All rights reserved.Thesis小田切 智海. An optimal skeletal element for DNA testing: Evalution of DNA quantity and quality from various bone types in routine forensic practice （DNA鑑定のための最適な骨組織の部位の探索：法医実務において採取した、複数の種類の骨組織から抽出したDNAの質および量に基づいた検証）. 信州大学, 2024, 博士論文. 博士（医学）, 甲第1376号, 令和06年03月31日授与.doctoral thesi
A preliminary study of IgG4 expression and its prognostic significance in oral squamous cell carcinoma(口腔扁平上皮癌におけるIgG4発現の予後的意義に関する予備的研究)
Get PDF信州大学(Shinshu university)博士（医学）次の雑誌に発表。 /BMC Cancer 24(1) :294(2024); doi:10.1186/s12885-024-12048-5 © 2024. The Author(s).Thesis福田 浩信. A preliminary study of IgG4 expression and its prognostic significance in oral squamous cell carcinoma(口腔扁平上皮癌におけるIgG4発現の予後的意義に関する予備的研究). 信州大学, 2024, 博士論文. 博士（医学）, 甲第1383号, 令和06年03月31日授与.doctoral thesi
Involvement of polycomb group genes in transition of differentiation state of pluripotent stem cells
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