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    Kapila Baideu: Hearing student questions

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    Can getting thought-provoking responses from a fictional character encourage students to ask more questions in science

    The PhD rollercoaster: highs, lows, and the moments that mattered

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    Dr. Sukanya recently finished her PhD. Here she reflects on the completed journey, and what is next

    The Role of the human microbiome in neurodegenerative diseases: A Perspective.

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    Advances in diagnostics, therapeutics, and large-scale clinical studies have significantly expanded our understanding how human health is shaped by the microorganisms that colonize the body since birth. This article explores the rapidly evolving field of human microbiome research, focusing upon how microbial communities influence neurological health and contribute to the development of neurodegenerative diseases (NDs). Multiple factors, including age, lifestyle, and immunological memory, are recognized as major determinants of an individual’s microbiome composition, which in turn can influence the onset and the progression of disorders such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and amyotrophic lateral sclerosis. These conditions have been linked to mechanisms including the aggregation of pathogenic proteins (e.g., amyloid-β and α-synuclein), inflammation driven by activation of the Toll-like receptor (TLR) signaling pathway, the NLRP3 inflammasome, as well as the modulatory effect of microbial metabolites such as short-chain fatty acids (SCFAs) and lipopolysaccharides (LPS). The article also highlights ongoing research and emerging strategies aimed at leveraging the human microbiome for better diagnosis, and management of NDs. © 2025 Elsevier B.V., All rights reserved

    Call for articles!

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    Case Comment - Dharam Singh v. State of Uttar Pradesh (2025)

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    The Supreme Court has reaffirmed that the State cannot treat essential public functions as temporary. Longstanding workers performing perennial duties deserve stability, security, and lawful recognition even in the face of financial constraints

    Submission guidelines for authors

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    Why are antivenoms not easily accessible in India?

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    A landmark 2020 study by researchers from Canada, India, and the U.K. estimated that between 2001 and 2014, a staggering 1.2 million snakebite deaths and three-times as many cases of disability occurred in Indi

    Crafting questions for diverse learning goals

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    Many children find mathematics tests ‘scary’ because they perceive them as high-stake assessments of their capacity to handle complex methods and formulas. Usually, tests and exams include questions designed to assess a student's understanding of a specific topic. But are questions only for testing and evaluation? A closer look reveals that questions have the potential to accomplish much more. For example, Socrates used questions to explore complex ideas, challenge assumptions, and pursue wisdom

    Montessori approach: An introduction to selected materials and how to re-create them (part 2)

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    Ever wondered how simple, hands-on materials can unlock a child's potential? Discover cost-effective ways to bring Montessori magic into your home while reaping the benefits of a method that fosters independence, creativity, and a lifelong love of learning

    India’s consensus on school education makes space for optimism

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    A remarkable convergence of views on this elementary matter of the country’s social and economic well-being offers us the common ground needed to do what must be done for education. Here’s what all parties largely agree on

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