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Poly(N-isopropylacrylamide-co-allylamine) (PNIPAM-co-ALA) nanospheres for the thermally triggered release of Bacteriophage K
Due to the increased prevalence of resistant bacterial isolates which are no longer susceptible to antibiotic treatment, recent emphasis has been placed on finding alternative modes of treatment of wound infections. Bacteriophage have long been investigated for their antimicrobial properties, yet the utilization of phage therapy for the treatment of wound infections relies on a suitable delivery system. Poly(N-isopropylacrylamide) (PNIPAM) is a thermally responsive polymer which undergoes a temperature dependent phase transition at a critical solution temperature. Bacteriophage K has been successfully formulated with PNIPAM nanospheres copolymerized with allylamine (PNIPAM-co-ALA). By utilizing a temperature responsive polymer it has been possible to engineer the nanospheres to collapse at an elevated temperature associated with a bacterial skin infection. The nanogels were reacted with surface deposited maleic anhydride in order to anchor the nanogels to non-woven fabric. Bacteriophage incorporated PNIPAM-co-ALA nanospheres demonstrated successful bacterial lysis of a clinically relevant bacterial isolate - Staphylococcus aureus ST228 at 37°C, whilst bacterial growth was unaffected at 25°C, thus providing a thermally triggered release of bacteriophage.Dynamic Light Scattering
IR Spectroscopy
Zeta Potential MeasurementsGraphs created in Origi
Dataset for Optimization of Drilling Resistance Measurement (DRM) user-controlled variables
This data set contains the raw data used to plot Figures 4, 5, 6, 7 and 8 from the paper. These are clearly identified in the spreadsheet alongside the relevant data. A more detailed description is provided below.
The dataset provide the raw data used to produce a plot of average drilling resistance versus hole number in an artificial reference stone which was used for wear-correction purposes. (see figure 4) Data used to produce a summary of drilling the data processing methodology used is also provided. This consists of drilling resistance against depth for three representative trials performed on Bath stone at 10 mm/min penetration rate and 600 RPM. The depth specific average resulting from averaging each of the three trials at each particular depth is shown. (see figure 5) Data showing the variation of average drilling resistance with penetration rate and rotational speed on a Bath stone and artificial reference stone is provided. (see figure 6) Data showing the linear relationship between radius-independent average drilling resistance and different PR/RPM settings on Bath stone and artificial reference stone is provided (see figure 7) The coefficient of variation at different PR/RPM settings on Bath stone and artificial reference stone is given.The measurements were made using a SINT Technology cordless Drilling Resistance Measurement System (DRMS), using a polycrystalline diamond-coated, flat-tipped drill bit of 5 mm diameter with back rake angle of 0°. For further details of the methodology, please refer to the associated paper.Calculations were performed using Microsoft Excel 2016
Dataset for "Bend-strength of novel filament wound shear reinforcement"
This dataset contains the results of tensile tests reported in the paper "Bend-strength of novel filament wound shear reinforcement". The tests were conducted according to the standards ISO 527-1 and ISO 527-5 on beam specimens manufactured using filament wound fibre reinforced polymers (W-FRP), except that a 500mm specimen length was used instead of the prescribed 250mm. The mid-section of each specimen was instrumented with a uniaxial strain gauge having 6 mm gauge length. The tests were performed in displacement control at 1.0 mm/min. The results were used to calculate the 25% and the 50% of the failure load and corresponding values of strains for each tested samples, along with the modulus of elasticity.Full details of the methodology can be found in the "Test methodology" section of the associated paper
Regenerated Cellulose Hydrogels as Bioaffinity Attachment Supports for Carbohydrate-Binding Module 1
Modification of cellulose hydrogels by choice of cellulose and regeneration solvent influences the surface area accessible to a family 1 carbohydrate-binding module, its affinity to the cellulose material and rate of migration through the hydrogel. The hydrogels may be used as support materials in bioaffinity applications but a compromise between accessible surface area and affinity, or migration rate, must be made.Fitted pXRD data may be viewed with Fityk 0.9.8 (free download)
NMR relaxometry data may be viewed using Origin, or Origin Viewer (free download)
Original confocal images may be viewed using ZEN (blue edition) (free download
Data supporting: "Microwave-assisted deep eutectic-solvothermal preparation of iron oxide nanoparticles for photoelectrochemical solar water splitting"
This dataset contains freely-available raw data in support of the named article (10.1039/C7TA02078C), including data from powder X-Ray diffraction, magnetometry measurements, Raman spectroscopy, wide-angle X-Ray scattering performed at the I22 beamline of Diamond Light Source, and photoelectrochemical measurements.WAXS: Data were collected on pure, and heat-treated DES samples, using the wide-angle detector at the I22 instrument of Diamond Light Source, UK. Samples were measured in glass capillaries at 30 C.
XRD: Diffraction data of the prepared powders were collected using a Bruker D8-ADVANCE instrument provided by the University of Bath CCAF.
Magnetometry: M(H) and M(T) measurements of the prepared solids were made using either a Quantum Design PPMS Vibrating Sample Magnetometer, or a Quantum Design MPMS-XL SQUID Magnetometer.
Photoelectrochemistry: PEC measurements were made of the prepared photoanodes using an in-house solar simulator and a three-electrode cell.
Full details of data collection methodology are given in the article.WAXS data were treated using the DAWN software suite, with the following processing steps performed:
- Detector calibration
- Masking
- Calculation of errors
- Azimuthal reduction (I vs q reduction)
- Division by I(t) (Transmitted intensity)
- Multiplication by I(0) (Primary beam intensity)
- Background subtraction
No significant processing steps can be reported for the other data givenhere, other than basic background subtraction (XRD), and normalisation to either the sample mass (magnetometry measurements) or the sample area (PEC measurements)Where possible, all data has been provided as tab-delimited text files. Due to the large volume of data, the magnetometry data has been provided as a collection of Microsoft Excel sheets
Dataset for ''Tetrabutyl ammonium cation for moisture-resistant and semitransparent perovskite solar cells''
This dataset consists of spreadsheets containing JV curves, UV-Vis spectra and XRD patterns of halide perovskite based films and solar cells. The dataset contains also top-view AFM and SEM images of halide perovskite films and photos of contact angles and profilometer measurements of the surface. These data were taken between February 2017 and July 2017 and they have been used to support the results of the manuscript titled: ''Tetrabutyl ammonium cation for moisture-resistant and semitransparent perovskite solar cells''. The purpose was to collect the data necessary to show the fabrication of halide perovskite solar cells with good photovoltaic performance, higher moisture stability and better morphology than standard perovskite devices. All the data used to support the conclusion of the manuscript are included in the dataset.JV curves and Stability data were measured using a Keithley 2601A potentiostat under 1 sun intensity and AM 1.5. Devices were sweeped at 100 mV/sec from 1.2V to 0V. Data consist of excel spreadsheets with Voltage Vs current.
SEM images were taken on a JEOL SEM 6480LV
AFM images were taken on a Nanosurf easyscan 2 FlexAFM
XRD patterns were measured using a Bruker Adv D8 x-ray diffractometer between 5 and 80 degrees. Data consist of excel spreadsheets with 2theta angle vs intensity peaks
UV-Vis spectra were taken on a Perkin Elmer Lambda 750S spectrometer. Data consist of excel spreadsheet with lambda vs reflectance and transmittance intensityAll data have been collected at University of Bath in the Chemistry department and the Microscopy and Analysis Suite (MAS)
Dataset for "An endlessly adiabatic fibre with a logarithmic refractive index distribution"
This dataset contains the data underlying the results reported in K. Harrington et al., "An endlessly adiabatic fibre with a logarithmic refractive index distribution". The data includes the results of calculations and measurements of a fibre with a novel refractive index distribution. This includes calculated mode field diameters for various outer diameters of the fibre. Also included are optical micrographs and near-field images recorded by digital sensors and stress distributions for fibres made with different drawing conditions.The methodology used to obtain the data is described in the paper K. Harrington et al., "An endlessly adiabatic fibre with a logarithmic refractive index distribution".The tabular data files (*.txt) are presented as tab-separated values
Dataset for resource-efficient fibre-integrated temporal multiplexing of heralded single photons
Research data for manuscript "Resource-efficient fibre-integrated temporal multiplexing of heralded single photons". The raw data were collected using home-built single photon coincidence counting electronics programmed in a field-programmable gate array. The number of photon pairs detected were measured as a function of laser pump power, with and without the loop multiplexing protocol active.Photon counting data collected using a home-built field-programmable gate array based counting system; the raw and analysed data are stored in Matlab workspace variables. Datasets are included for coincidence counting experiments, with and without the loop multiplexing protocol active.The data were processed in MATLAB R2016b according to the included .m script. The data are stored as a .mat file. Variable names are detailed as commented in the accompanying .m script. Variable names ending in 'n' refer to data collected without the multiplexing protocol active indicating "no loop present". Variable names ending in 'l' refer to data collected with the multiplexing protocol active indicating "loop present".MATLAB is required to read data files.Full details of the methodology are provided in the associated paper. A post-print of this paper is available from https://arxiv.org/abs/1706.01838
Dataset for application of expanded perlite encapsulated bacteria and growth media for self-healing concrete
The dataset contains the data used to prepare the research paper "Application of expanded perlite encapsulated bacteria and growth media for self-healing concrete". This research investigated the self-healing performance of concrete in terms of the number of bacterial spores required and the concentration and composition of nutrients and precursors. The dataset contains:
1. The particle size distribution of the perlite used.
2. Calculations of the number of bacterial cells to calcium acetate.
3. The optical density of bacteria growth in three media.
4. Calcite productivity in the three media in relation to number of bacteria cells.
5. Details of the mortar mix designs.
6. The mean initial surface absorption of mortars from 10 to 120 minutes
Data for 'Fast Matrix Operations in Computer Algebra'
This data package contains Maple worksheets with code executing algorithms pertaining to fraction-free Bunch-Hopcroft matrix inversion. The worksheets also include timing procedures used to obtain a log-log plot to describe the experimental asymptotic behaviour of the run time of the new fraction free algorithm. The plot and corresponding raw data are also included in the package. More information about these algorithms is available from the corresponding papers, 'Fast Matrix Operations in Computer Algebra' and 'On Fast Matrix Inversion'.The code was written at the University of Bath by Zak Tonks. "Fraction-Free Bunch-Hopcroft" is an adaptation of Bunch-Hopcroft matrix inversion as per references. The other algorithms used are as per references. Such code was written in Maple courtesy of Maplesoft.
The experimental timing data was obtained using code from the worksheets by Zak Tonks, in Maple 2016. The CodeTools package in Maple was used to obtain CPU times for computations.The timing data were formatted in a log-log plot in Maple by Zak Tonks.The experimentation was originally performed in Maple 2016, using the version of CodeTools packaged with it. The current worksheets were saved in Maple 2017. The specification of the computer used for experimentation is as follows:
- Intel Micro ATX DQ67SW
- Intel Core I5 -2500 3.33GHz
- 16GB RAM'On Fast Matrix Inversion' is an extension paper detailing further developments on 'Fast Matrix Operations in Computer Algebra'. 'On Fast Matrix Inversion'...mw and 'Fast Matrix Operations...'...mw detail algorithms as per each paper respectively. In particular, a newer fraction-free Bunch-Hopcroft algorithm is presented in the former worksheet.
Original algorithm for "Strassen-Winograd" (referred to as Strassen in worksheets and Winograd in 'Fast-Matrix Operations in Computer Algebra') can be found at [3]. Original algorithm for "Bunch-Hopcroft" can be found at [2]. Original Strassen's algorithm at [1]. "Fraction-Free Bunch-Hopcroft" an adaptation of [2].
References:
[1] V. Strassen, “Gaussian Elimination is not Optimal,” Numer. Math., vol. 13, pp. 354–356, 1969.
[2] J. Bunch and J. Hopcroft, “Triangular factorization and inversion by fast matrix multiplication,” Mathematics of Computation, vol. 28, pp. 231–236, 1974.
[3] S. Winograd, “On multiplication of 2 x 2 matrices,” Linearalgebra and its applications, vol. 4, pp. 381–388, 1971