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    1056 research outputs found

    Dataset for "All-fibre wavefront sensor"

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    We have developed a tip-tilt wavefront sensor based on a tapered three-core optical fibre. In this device, a coupled region at the sensing tip of the fibre converts phase information from an incoming wavefront into intensity information within each of the cores. The sensor uses minimal information to infer tip-tilt and is compatible with remote detector arrays, making it highly relevant for use in ground-based astronomical telescopes. This repository contains three sets of 49 near-field images, which capture the response of our all-fibre wavefront sensor to incoming wavefronts of changing tip/tilt. We have included an analysis/plotting script (in Matlab) to evaluate the centroid positions from the acquired images and plot these alongside analytical values. These files comprise the complete set of experimental results presented in "All-fibre wavefront sensor".Full details of the methodology may be found in the associated manuscript

    TIEGCM Halloween Experiments – Halloween thermosphere (b & g)

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    This dataset contains the model run for the period between 15 and 16 October 2003, with all thermospheric fields replaced with the corresponding fields from the storm time run (29 to 30 October 2003) at 6 a.m. on 15 October.Full details of the methodology may be found in the 'Method' section of the associated paper.Details about this dataset are available from the main record: https://doi.org/10.15125/BATH-0057

    Framework Index for "Tobacco Control Legislation in Small Island Nations: Adoption of WHO FCTC Article 13 in the Federated States of Micronesia"

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    Framework index of the current tobacco advertising, promotion and sponsorship policy (TAPS) environment in the Federated States of Micronesia (FSM). Three research questions underpinned this study: What is the context surrounding the current TAPS policy in FSM? What circumstances led to the development of the current legislative text? And, What is the involvement of the different actors in developing and monitoring the TAPS legislation? A health policy triangle model was used as a conceptual approach on publicly available documents. The thematic framework approach informed the analysis of thirty nine documents. Four themes generated from the analysis: 1) the adoption of TAPS provisions due to international commitments, 2) the limited involvement of sub-national actors, 3) the problematic tobacco control program’s funding and administration and 4) the incomplete documentation of TAPS. This file provides the coded text used for the generated findings, stratified per theme, sub-theme and category. Links to original material are provided in the reference list.We employed the health policy triangle model as a conceptual approach and the READ technique to inform the study procedure. We collected 308 documents from publicly available resources (see online supplementary appendix 1 in the associated paper) with the combination of the keywords “Micronesia” (or “Federated States of Micronesia” or “FSM”) and “tobacco advertising” (or “tobacco marketing” or “tobacco promotion”). We excluded (269 total) documents as irrelevant or with repeat information. We collected data between November-December of 2020 (except the Global Youth Tobacco Survey, 2019 collected in 2022), and no retrospective chronological limitation was set. Thirthy nine documents included for analysis.No changes occured before the analysis. We drew on the thematic framework approach, to inform the study analysis. Categories, themes and sub-themes created based on the available data.All data was coded using NVivo 12.0 software, but the file presented here is in Rich Text Format (RTF)

    Dataset for article entitled "An empirical evaluation of methodologies used for emotion recognition via EEG signals"

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    The data is split into two parts according to the two experiments described within the article. The dataset includes movies and python codes for classifying emotions from experiment 1, and EEG and ERP measurements from experiment 2 along with associated code for analyzing those data. Experiment 1 tests the validity of the SEED dataset collated by Zheng, Dong, & Lu (2014) and, subsequently, our own stimuli. The objective was to test whether previous literature using such datasets as the aformentioned dataset by Zheng et al. is purportedly classifying between emotions based on emotion-related signals of interest and/or non-emotional ‘noise’. Experiment 2 used stimuli that have been well-validated within the psychological literature as reliably evoking specific embodiments of emotions within the viewer, namely the NimStim face and ADFES-BIV datasets with the objective of classifying a person's emotional status using EEG. All data was processed and analyses run in MATLAB or Python. All datasets used are included within the folders accompanied by the MATLAB or Python scripts for collating separable matrices and running the action.Running the scripts requires MATLAB and Python 3 (with packages imageio, matplotlib, myknn, NumPy, pylab, SciPy, sklearn)

    Supplementary materials for "Understanding University Student Priorities for Mental Health and Well-being Support: A Mixed-Methods Exploration using the Person-Based Approach"

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    These supplementary materials comprise some of the study materials used in a mixed-methods exploration of student engagement with and priorities for well-being and mental health support at university. They include the content of an online survey instrument (part 1, quantitative), the focus group discussion schedule (part 2, qualitative), and anonymised data from the survey and focus groups. Research took place in the summer of 2020; the participants were students of the University of Bath at that time.Full details of the methodology may be found in the associated paper. The survey instrument and focus group schedule are included in the dataset.The data archived here has been anonymised in line with the nature of informed consent obtained from participants.Transcripts and descriptively analysed survey data are in MS Word (docx) format. Anonymised and pre-processed survey data are in MS Excel (xlsx) format. The qualitative analysis was conducted in NVivo.The online survey was open between 25th June and 5th August 2020. The three focus groups took place in July 2020

    Data sets for "Structure of molten NaCl and the decay of the pair-correlations"

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    Data sets used to prepare Figure 1 -14 in the Journal of Chemical Physics article entitled "Structure of molten NaCl and the decay of the pair-correlations." The data sets refer to the measured and simulated structure and thermodynamic properties of molten NaCl.The data sets were collected using the methods described in the published paper.The data sets were analysed using the methods described in the published paper.The figures were prepared using QtGrace (https://sourceforge.net/projects/qtgrace/). The data set corresponding to a plotted curve within an QtGrace file can be identified by clicking on that curve.The files are labelled according to the corresponding figure numbers. The units for each axis are identified on the plots

    Dataset for "Tri-mode optical biopsy probe with fluorescence endomicroscopy, Raman spectroscopy, and time resolved fluorescence spectroscopy"

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    Data supporting "Tri-mode optical biopsy probe with fluorescence endomicroscopy, Raman spectroscopy, and time resolved fluorescence spectroscopy", including figures from the article, supplementary figures and diagrams of the experimental setups used, bend loss data from the fibre used for Time Resolved Fluorescence Spectroscopy (TRFS), and the raw Optical EndoMicroscopy (OEM) video files used to produce figure 5. This body of work characterises the performance of an optical fibre probe that was designed and built to provide three complimentary optical methods of endoscopically interrogating human tissue: Optical EndoMicroscopy (OEM), Time Resolved Fluorescence Spectroscopy (TRFS), and Raman spectroscopy. Its ability to characterise standard targets was evaluated, both when subjected to a sequence of bends, and then within a model of a human lung. Ex-vivo human lung tissue was also used as a target to explore its tissue characterisation capabilities. These data sets form part of the pre-clinical testing and validation required for progression to its intended application in pulmonology.Full details of the methodology can be found in the associated paper

    Dataset for "Effect of fibre loading on the microstructural, electrical, and mechanical properties of carbon fibre incorporated smart cement-based composites"

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    The data "Dataset_Frontiers" is pertinent to the study in the paper "Effect of carbon fibre loading on the microstructural, electrical, and mechanical properties of cement-based sensors" published under the research topic "Smart Concrete to Deliver Sustainable Infrastructures" in the Journal: Frontiers in materials The purpose of collecting the data was to understand the transitional behaviours of microstructural, electrical, and mechanical properties of cement-based sensors, which occur while increasing the amount of the carbon fibre from lower to higher dosages. This will facilitate the understanding on the improvement of self-sensing performance of cement-based sensors by improving the manufacturing process and mixing design, and the use of multi-functional in-situ self-sensing. The data contains information of the electrical and mechanical properties of cement-based sensors containing carbon fibres from zero to 2.4% by volume (vol.%). Two excel spread sheets are included in the zip file. In the "Electrical properties.xlsx": the column of "Sensor (S/m)" contains data for the bulk conductivity of cement-based sensors, the column of "Solution mixture (S/m)" contains data for the bulk conductivity of diluted calcium hydroxide (CH) solution incorporating carbon fibres. In the "Mechanical properties.xlsx": the column of "Rf (MPa) " contains data for the flexural strength of cement-based sensors, the column of "Rc (MPa) " contains data for the compressive strength of cement-based sensors.The bulk conductivity was obtained via the impedance measurement under the voltage of 707.107 mV, and the frequency range was 1 Hz – 10 MHz. The compressive and flexural strengths were obtained via uniaxial compression and three-point bending.The impedance response was collected with a Newtons4th PSM 3750 frequency analyser (Newtons4th Ltd., Leicester, UK) interfaced with an impedance analyser. The Impedance analysis software was Zview (Scribner Associates Inc, North Carolina, USA). The compression and three-point bending machines were from CONTROLS Ltd, Hertfordshire, UK, as well as Instron, Buckinghamshire, UK, respectively

    Project PXD035503: "The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis"

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    Mechanistic studies of how protein ubiquitylation regulates the cell cycle, in particular during mitosis, have provided unique insights which have contributed to the emergence of the ‘Ubiquitin code’. In contrast to RING E3 ubiquitin ligases such as the APC/c ligase complex, the contribution of other E3 ligase families during cell cycle progression remains less well understood. Similarly, the roles of ubiquitin chain types beyond homotypic K48 chains in S-phase or branched K11/K48 chains during mitosis, also remains to be fully determined. Our recent findings that HECTD1 ubiquitin ligase activity assembles branched K29/K48 ubiquitin linkages prompted us to evaluate its function during the cell cycle. We used transient knockdown and genetic knockout to show that HECTD1 depletion in HEK293T and HeLa cells decreases cell number and we established that this is mediated through loss of ubiquitin ligase activity. Interestingly, we found that HECTD1 depletion increases the proportion of cells with aligned chromosomes (Prometa/Metaphase) and we confirmed this molecularly using phospho-Histone H3 (Ser28) as a marker of mitosis. Time-lapse microscopy of NEBD to anaphase onset established that HECTD1-depleted cells take on average longer to go through mitosis. To explore the underlying mechanisms, we used proteomics and identified the interactome of endogenous HECTD1 in cells synchronized in mitosis and validated the Mitosis Checkpoint Complex protein BUB3 as a novel HECTD1 interactor. In line with this, we found that HECTD1 depletion reduces the activity of the Spindle Assembly Checkpoint. Overall, our data suggests a novel role for HECTD1 ubiquitin ligase activity during mitosis.HEK293T cells were synchronised in late G2 and mitosis as described above. Four μg of IgG or of a HECTD1 antibody (Ab101992) were coated onto Dynabead magnetic beads and incubated with either lysates from G2 or M-phase synchronised cells for 1 hr at RT prior to washes, and denaturation in 2xLDS sample buffer/100 mM DTT at 95°C for 5 min. Samples were then loaded onto a 4-12% Bis-Tris SDS polyacrylamide gel which was then stained with Imperial Protein Stain (ThermoFisher Scientific). Gel lanes were sliced into of 1-2 mm2 pieces and processed by in-gel trypsin digestion. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) using an LTQ Orbitrap Velos (ThermoFisher Scientific) mass spectrometer coupled to an Ultimate 3000 nano-ultra performance liquid chromatography (UPLC) system (Dionex, Sunnyvale, CA, USA). The mass spectrometer was operated in data-dependent acquisition mode using a Top10 method and a 32-minute liquid chromatography gradient. The MS1 survey scans were acquired in the Orbitrap at a resolution of 30,000 and an m/z range of 300-2,000. MS2 data were acquired in the Ion Trap and precursor ion isolation was performed with an isolation width of 2.0 Da and CID activation with a normalised collision energy of 35.The LC-MS/MS data were searched with the MASCOT search algorithm [1]. Mascot distiller was used to produce Mascot compatible (.mgf) files from the raw LC-MS/MS data. Mascot (Matrix Science, algorithm version 2.2.04) was used to perform database searches of the Uniprot database without taxonomy restriction (14,423,061 entries). Variables were set to: 2+ and 3+ ions, peptide mass tolerance 10 ppm, fragment mass tolerance 0.8 Da, number of missed cleavages: one, instrument type: ESI-TRAP, variable modifications: Carbamidomethylation (Cys), Oxidation (Met). N-terminal pyroglutamate (Gln->pyroGly), phosphorylation (Ser, Thr, Tyr). MS/MS data were further validated using Scaffold (http://www.proteomesoftware.com). [1] Perkins, D. N., Pappin, D. J., Creasy, D. M. & Cottrell, J. S. (1999) Probability-based protein identification by searching sequence databases using mass spectrometry data., Electrophoresis. 20, 3551-3567

    TIEGCM November Experiment – November background run (truth)

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    This dataset contains the model run for the period between 20 and 21 November 2003, representing a storm period. This represents the truth against which the forecasts were compared.Full details of the methodology may be found in the 'Method' section of the associated paper.Details about this dataset are available from the main record: https://doi.org/10.15125/BATH-0057

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